Urs Karrer, Sophie Sierro, Markus Wagner, Annette Oxenius, Hartmut Hengel, Ulrich H. Koszinowski, Rodney E. Phillips, and Paul Klenerman. Memory Inflation: Continous Accumulation of Antiviral CD8+ T Cells Over Time. The Journal of Immunology 2003; 170:2022-2029.
To draw attention to additional relevant research by Holtappels et al., the authors wish to add the following as the fourth sentence in the third paragraph of the Discussion.
Enrichment of pp89- and m164-specific but not m3-, m04-, or M84-specific CD62Llo effector memory CD8+ T cells in the latent phase of MCMV infection has been recently observed by Holtappels et al. using a model of MCMV-induced interstitial pneumonia after immunosuppression by irradiation and syngeneic bone marrow transplantation, and a role for such cells in control of viral latency proposed (12, 54).
The authors also wish to add the following reference.
54. Holtappels, R., M. F. Palh-Seibert, D. Thomas, and M. J. Reddehase. 2000. Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62Llo memory-effector cell pool during latent murine cytomegalovirus infectin of the lungs. J. Virol. 74:11495.
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