Persistent Decreases in Blood Plasmacytoid Dendritic Cell Number and Function Despite Effective Highly Active Antiretroviral Therapy and Increased Blood Myeloid Dendritic Cells in HIV-Infected Individuals

^*HIV Immunopathogenesis Laboratory, Wistar Institute, and
^†Children’s Hospital of Philadelphia, Division of Immunologic and Infectious Diseases, Philadelphia, PA 19104;
^‡Philadelphia Field Initiation Group for HIV Trials, Philadelphia, PA 19103; and
^§Laboratory for Immunological Research, Schering-Plough, Dardilly, France

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Article usage

Article usage: April 2002 to January 2021

	Abstract	Full	Pdf
Apr 2002	109	114	189
May 2002	38	183	198
Jun 2002	7	101	89
Jul 2002	7	81	82
Aug 2002	4	47	41
Sep 2002	0	47	44
Oct 2002	5	53	43
Nov 2002	3	60	41
Dec 2002	8	26	27
Total 2002	181	712	754
Jan 2003	3	29	29
Feb 2003	2	22	21
Mar 2003	2	25	19
Apr 2003	4	25	14
May 2003	2	44	45
Jun 2003	4	22	28
Jul 2003	5	30	31
Aug 2003	6	45	27
Sep 2003	13	23	16
Oct 2003	10	23	18
Nov 2003	9	33	21
Dec 2003	14	42	27
Total 2003	74	363	296
Jan 2004	12	32	31
Feb 2004	10	49	31
Mar 2004	8	48	36
Apr 2004	12	41	37
May 2004	8	30	24
Jun 2004	11	34	17
Jul 2004	12	28	23
Aug 2004	12	30	22
Sep 2004	9	39	24
Oct 2004	6	38	23
Nov 2004	8	34	21
Dec 2004	7	32	15
Total 2004	115	435	304
Jan 2005	5	42	24
Feb 2005	6	40	16
Mar 2005	10	42	27
Apr 2005	9	29	39
May 2005	4	25	22
Jun 2005	4	32	16
Jul 2005	4	28	13
Aug 2005	7	26	20
Sep 2005	6	22	21
Oct 2005	9	31	42
Nov 2005	8	40	30
Dec 2005	9	38	34
Total 2005	81	395	304
Jan 2006	4	40	15
Feb 2006	2	23	8
Mar 2006	5	28	11
Apr 2006	7	28	13
May 2006	8	24	17
Jun 2006	5	15	9
Jul 2006	5	21	13
Aug 2006	9	20	19
Sep 2006	10	38	16
Oct 2006	4	28	18
Nov 2006	14	26	15
Dec 2006	9	33	12
Total 2006	82	324	166
Jan 2007	14	35	895
Feb 2007	14	17	16
Mar 2007	18	24	14
Apr 2007	12	13	11
May 2007	9	18	9
Jun 2007	5	23	11
Jul 2007	14	35	15
Aug 2007	2	19	8
Sep 2007	6	24	13
Oct 2007	7	15	7
Nov 2007	9	14	15
Dec 2007	5	9	4
Total 2007	115	246	1018
Jan 2008	2	15	6
Feb 2008	6	13	9
Mar 2008	13	15	12
Apr 2008	6	18	14
May 2008	9	15	13
Jun 2008	22	22	16
Jul 2008	6	11	12
Aug 2008	15	14	11
Sep 2008	21	14	11
Oct 2008	19	24	12
Nov 2008	13	9	4
Dec 2008	8	9	11
Total 2008	140	179	131
Jan 2009	7	14	14
Feb 2009	18	12	13
Mar 2009	15	9	2
Apr 2009	7	11	13
May 2009	12	14	18
Jun 2009	5	9	11
Jul 2009	12	13	13
Aug 2009	9	13	15
Sep 2009	12	18	18
Oct 2009	13	19	12
Nov 2009	9	15	12
Dec 2009	7	13	12
Total 2009	126	160	153
Jan 2010	10	7	9
Feb 2010	3	11	8
Mar 2010	8	15	11
Apr 2010	6	25	8
May 2010	7	27	13
Jun 2010	10	18	10
Jul 2010	11	10	10
Aug 2010	6	21	5
Sep 2010	6	245	4
Oct 2010	10	15	13
Nov 2010	4	14	9
Dec 2010	12	7	8
Total 2010	93	415	108
Jan 2011	4	31	26
Feb 2011	7	10	26
Mar 2011	11	15	14
Apr 2011	8	16	11
May 2011	10	13	12
Jun 2011	3	43	18
Jul 2011	16	7	6
Aug 2011	13	9	12
Sep 2011	28	16	13
Oct 2011	24	14	8
Nov 2011	19	12	13
Dec 2011	13	11	16
Total 2011	156	197	175
Jan 2012	15	9	12
Feb 2012	21	10	10
Mar 2012	20	20	8
Apr 2012	16	10	6
May 2012	10	12	13
Jun 2012	11	15	10
Jul 2012	8	8	8
Aug 2012	14	12	8
Sep 2012	15	8	9
Oct 2012	15	17	9
Nov 2012	16	12	11
Dec 2012	11	19	12
Total 2012	172	152	116
Jan 2013	13	15	13
Feb 2013	14	8	7
Mar 2013	28	10	7
Apr 2013	15	17	12
May 2013	21	8	9
Jun 2013	22	7	7
Jul 2013	19	4	7
Aug 2013	14	5	7
Sep 2013	17	6	11
Oct 2013	10	10	6
Nov 2013	14	9	6
Dec 2013	15	4	5
Total 2013	202	103	97
Jan 2014	30	10	9
Feb 2014	7	9	8
Mar 2014	18	15	16
Apr 2014	8	6	11
May 2014	20	7	34
Jun 2014	19	5	6
Jul 2014	34	14	17
Aug 2014	3	7	7
Sep 2014	13	5	7
Oct 2014	13	5	12
Nov 2014	21	7	7
Dec 2014	11	2	5
Total 2014	197	92	139
Jan 2015	23	13	105
Feb 2015	8	3	160
Mar 2015	19	11	94
Apr 2015	27	6	54
May 2015	6	19	64
Jun 2015	14	5	51
Jul 2015	8	4	9
Aug 2015	9	7	6
Sep 2015	17	7	7
Oct 2015	49	7	3
Nov 2015	10	9	7
Dec 2015	11	5	10
Total 2015	201	96	570
Jan 2016	14	15	7
Feb 2016	6	8	9
Mar 2016	2	24	11
Apr 2016	9	4	3
May 2016	4	14	9
Jun 2016	12	5	4
Jul 2016	1	5	3
Aug 2016	6	11	6
Sep 2016	10	19	7
Oct 2016	7	6	6
Nov 2016	13	4	3
Dec 2016	90	5	4
Total 2016	174	120	72
Jan 2017	18	7	2
Feb 2017	5	12	8
Mar 2017	5	7	9
Apr 2017	9	16	5
May 2017	9	19	16
Jun 2017	4	9	0
Jul 2017	9	17	7
Aug 2017	0	1	4
Sep 2017	2	4	1
Oct 2017	9	12	11
Nov 2017	12	4	6
Dec 2017	5	9	4
Total 2017	87	117	73
Jan 2018	5	9	4
Feb 2018	5	12	7
Mar 2018	4	10	5
Apr 2018	3	8	4
May 2018	3	32	2
Jun 2018	3	19	2
Jul 2018	4	11	3
Aug 2018	3	8	2
Sep 2018	1	15	5
Oct 2018	6	16	8
Nov 2018	4	11	4
Dec 2018	2	12	10
Total 2018	43	163	56
Jan 2019	1	9	3
Feb 2019	3	9	0
Mar 2019	4	17	10
Apr 2019	4	9	10
May 2019	8	6	13
Jun 2019	2	11	2
Jul 2019	4	15	15
Aug 2019	2	6	3
Sep 2019	2	43	21
Oct 2019	3	79	12
Nov 2019	2	4	5
Dec 2019	5	14	9
Total 2019	40	222	103
Jan 2020	4	109	4
Feb 2020	1	11	8
Mar 2020	10	39	11
Apr 2020	3	14	3
May 2020	2	12	4
Jun 2020	2	18	6
Jul 2020	1	7	2
Aug 2020	0	32	5
Sep 2020	3	20	7
Oct 2020	0	19	13
Nov 2020	5	14	9
Dec 2020	6	7	8
Total 2020	37	302	80
Jan 2021	2	4	9
Total 2021	2	4	9
Total	2318	4797	4724