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About the Cover

April 1, 2002; Volume 168,Issue 7

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On the Cover: Tie2-tmTNF-transgenic mice are protected from Con A-induced DNA damage in the liver. Confocal laser imaging of double-immunofluorescent TUNEL (green)- and PECAM-1 (red)-stained liver sections of Con A-treated (20 mg/kg) wild-type mice (B) and tie2-tmTNF-transgenic mice (C). A, DNase I treatment (positive control). Arrows point to TUNEL-positive endothelial cells (yellow). Quantification of TUNEL-positive endothelial cells revealed (±SD): wild-type, untreated, 1.8 ± 1.2 cells/mm2; wild-type, 8 h Con A, 17.1 ± 8.2 cells/mm2; tie2-tmTNF, untreated, 1.0 ± 1.0 cells/mm2; and tie2-tmTNF, 8 h Con A, 8.2 ± 4.1 cells/mm2. (Figure 6 from Willuweit, A., G. Sass, A. Schöneberg, U. Eisel, G. Tiegs, and M. Clauss. Chronic Inflammation and Protection from Acute Hepatitis in Transgenic Mice Expressing TNF in Endothelial Cells. 3944)

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This Issue

The Journal of Immunology: 168 (7)
The Journal of Immunology
Vol. 168, Issue 7
1 Apr 2002
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  • CUTTING EDGE
  • CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • HOST DEFENSE
  • INFLAMMATION
  • CLINICAL IMMUNOLOGY
  • CORRECTIONS
  • Highlights
  • Most Cited
  • Most Read
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606