Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

^*Immunology Division, Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, and
^†Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia; and
^‡Cooperative Research Center for Vaccine Technology, Queensland Institute of Medical Research, Royal Brisbane Hospital, Herston, Queensland, Australia

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Article usage: January 2002 to July 2022

	Abstract	Full	Pdf
Jan 2002	448	405	608
Feb 2002	90	145	200
Mar 2002	23	61	119
Apr 2002	10	52	53
May 2002	5	38	34
Jun 2002	8	31	28
Jul 2002	6	19	26
Aug 2002	5	18	24
Sep 2002	6	29	35
Oct 2002	2	52	50
Nov 2002	3	38	25
Dec 2002	3	19	29
Total 2002	609	907	1231
Jan 2003	2	38	41
Feb 2003	2	29	38
Mar 2003	2	42	77
Apr 2003	3	20	38
May 2003	4	23	29
Jun 2003	4	23	33
Jul 2003	4	20	28
Aug 2003	7	20	18
Sep 2003	14	30	24
Oct 2003	9	25	18
Nov 2003	13	41	28
Dec 2003	12	25	22
Total 2003	76	336	394
Jan 2004	9	27	19
Feb 2004	4	13	22
Mar 2004	9	28	22
Apr 2004	11	31	15
May 2004	11	21	23
Jun 2004	8	27	24
Jul 2004	5	15	20
Aug 2004	9	29	11
Sep 2004	6	20	15
Oct 2004	5	12	19
Nov 2004	4	21	17
Dec 2004	5	16	8
Total 2004	86	260	215
Jan 2005	7	15	9
Feb 2005	3	19	19
Mar 2005	10	32	24
Apr 2005	1	8	8
May 2005	4	8	33
Jun 2005	6	24	10
Jul 2005	2	16	10
Aug 2005	6	26	17
Sep 2005	4	12	12
Oct 2005	5	23	12
Nov 2005	5	12	8
Dec 2005	7	29	4
Total 2005	60	224	166
Jan 2006	2	7	6
Feb 2006	2	7	7
Mar 2006	3	9	3
Apr 2006	4	15	17
May 2006	4	9	7
Jun 2006	1	11	11
Jul 2006	2	6	6
Aug 2006	4	19	6
Sep 2006	2	9	14
Oct 2006	2	12	6
Nov 2006	1	9	6
Dec 2006	7	11	6
Total 2006	34	124	95
Jan 2007	4	10	4
Feb 2007	4	18	14
Mar 2007	2	14	10
Apr 2007	6	27	15
May 2007	4	34	24
Jun 2007	10	16	20
Jul 2007	5	27	18
Aug 2007	2	7	16
Sep 2007	3	11	18
Oct 2007	0	8	26
Nov 2007	12	17	19
Dec 2007	1	7	16
Total 2007	53	196	200
Jan 2008	4	11	9
Feb 2008	6	10	7
Mar 2008	13	16	10
Apr 2008	2	9	8
May 2008	6	10	11
Jun 2008	6	7	4
Jul 2008	4	4	6
Aug 2008	16	13	6
Sep 2008	25	6	7
Oct 2008	13	5	5
Nov 2008	7	14	7
Dec 2008	0	4	1
Total 2008	102	109	81
Jan 2009	6	9	8
Feb 2009	4	7	4
Mar 2009	6	6	6
Apr 2009	5	4	4
May 2009	2	5	8
Jun 2009	6	9	4
Jul 2009	5	13	6
Aug 2009	2	2	4
Sep 2009	6	5	7
Oct 2009	7	10	7
Nov 2009	3	3	8
Dec 2009	3	1	3
Total 2009	55	74	69
Jan 2010	0	6	6
Feb 2010	0	4	4
Mar 2010	4	8	8
Apr 2010	3	11	7
May 2010	2	9	5
Jun 2010	2	2	2
Jul 2010	3	5	3
Aug 2010	0	9	6
Sep 2010	0	3	3
Oct 2010	0	3	3
Nov 2010	2	1	3
Dec 2010	14	2	3
Total 2010	30	63	53
Jan 2011	6	2	1
Feb 2011	9	9	6
Mar 2011	7	6	8
Apr 2011	8	5	5
May 2011	8	3	6
Jun 2011	13	2	2
Jul 2011	3	1	5
Aug 2011	3	5	5
Sep 2011	8	2	3
Oct 2011	13	3	6
Nov 2011	4	5	5
Dec 2011	7	7	16
Total 2011	89	50	68
Jan 2012	5	2	1
Feb 2012	6	6	1
Mar 2012	15	6	5
Apr 2012	3	1	1
May 2012	2	1	1
Jun 2012	6	7	5
Jul 2012	31	14	2
Aug 2012	9	7	1
Sep 2012	5	1	4
Oct 2012	6	6	5
Nov 2012	8	3	4
Dec 2012	5	3	4
Total 2012	101	57	34
Jan 2013	8	2	1
Feb 2013	4	3	2
Mar 2013	9	6	6
Apr 2013	6	7	4
May 2013	6	5	5
Jun 2013	4	4	5
Jul 2013	5	2	1
Aug 2013	3	6	5
Sep 2013	3	4	4
Oct 2013	16	8	6
Nov 2013	5	1	3
Dec 2013	9	0	0
Total 2013	78	48	42
Jan 2014	11	3	2
Feb 2014	2	1	0
Mar 2014	2	2	1
Apr 2014	7	2	7
May 2014	10	5	3
Jun 2014	2	3	1
Jul 2014	18	8	6
Aug 2014	6	2	14
Sep 2014	3	4	1
Oct 2014	8	4	1
Nov 2014	4	1	0
Dec 2014	7	8	6
Total 2014	80	43	42
Jan 2015	6	3	1
Feb 2015	1	1	0
Mar 2015	4	2	5
Apr 2015	0	2	3
May 2015	1	0	1
Jul 2015	2	7	11
Aug 2015	2	2	3
Sep 2015	14	7	6
Oct 2015	6	4	1
Nov 2015	2	5	0
Dec 2015	4	2	4
Total 2015	42	35	35
Jan 2016	7	5	6
Feb 2016	2	2	6
Mar 2016	5	2	6
Apr 2016	2	8	3
May 2016	3	1	1
Jun 2016	3	2	4
Jul 2016	2	1	3
Aug 2016	0	0	1
Sep 2016	1	4	1
Oct 2016	6	2	5
Nov 2016	3	0	1
Dec 2016	1	1	0
Total 2016	35	28	37
Jan 2017	3	5	6
Feb 2017	0	3	1
Mar 2017	0	9	2
Apr 2017	1	1	0
May 2017	0	1	5
Jun 2017	0	2	0
Jul 2017	0	2	0
Aug 2017	0	6	1
Sep 2017	0	10	2
Oct 2017	1	2	1
Nov 2017	0	2	0
Dec 2017	2	3	3
Total 2017	7	46	21
Jan 2018	0	8	2
Feb 2018	1	4	3
Mar 2018	0	9	0
Apr 2018	0	10	3
May 2018	2	11	0
Jun 2018	1	5	0
Jul 2018	0	5	1
Aug 2018	0	9	0
Sep 2018	1	17	1
Oct 2018	0	71	0
Nov 2018	1	104	3
Dec 2018	0	11	4
Total 2018	6	264	17
Jan 2019	0	12	0
Feb 2019	4	51	10
Mar 2019	1	5	10
Apr 2019	4	8	5
May 2019	2	6	5
Jun 2019	0	7	1
Jul 2019	0	8	5
Aug 2019	2	14	8
Sep 2019	0	3	1
Oct 2019	1	26	2
Nov 2019	2	6	4
Dec 2019	1	16	7
Total 2019	17	162	58
Jan 2020	1	28	0
Feb 2020	2	12	2
Mar 2020	0	14	2
Apr 2020	1	7	2
May 2020	3	8	8
Jun 2020	0	4	3
Jul 2020	1	3	5
Aug 2020	1	16	0
Sep 2020	10	28	10
Oct 2020	1	47	9
Nov 2020	1	11	3
Dec 2020	3	7	1
Total 2020	24	185	45
Jan 2021	0	7	2
Feb 2021	1	13	7
Mar 2021	0	7	7
Apr 2021	0	13	7
May 2021	1	15	4
Jun 2021	2	86	4
Jul 2021	0	4	1
Aug 2021	3	4	4
Sep 2021	1	7	7
Oct 2021	0	9	16
Nov 2021	0	7	10
Dec 2021	0	11	4
Total 2021	8	183	73
Jan 2022	4	7	7
Feb 2022	1	3	1
Mar 2022	0	3	3
Apr 2022	1	0	2
May 2022	0	5	12
Jun 2022	0	6	7
Jul 2022	0	9	3
Total 2022	6	33	35
Total	1598	3427	3011