Table of Contents

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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  A Dual Role for TNF-α in Type 1 Diabetes: Islet-Specific Expression Abrogates the Ongoing Autoimmune Process When Induced Late but Not Early During Pathogenesis

  Urs Christen, Tom Wolfe, Ursula Möhrle, Anna C. Hughes, Evelyn Rodrigo, E. Allison Green, Richard A. Flavell and Matthias G. von Herrath

  J Immunol June 15, 2001, 166 (12) 7023-7032; DOI: https://doi.org/10.4049/jimmunol.166.12.7023
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  Infection of Human Macrophages and Dendritic Cells with Mycobacterium tuberculosis Induces a Differential Cytokine Gene Expression That Modulates T Cell Response

  Elena Giacomini, Elisabetta Iona, Lucietta Ferroni, Minja Miettinen, Lanfranco Fattorini, Graziella Orefici, Ilkka Julkunen and Eliana M. Coccia

  J Immunol June 15, 2001, 166 (12) 7033-7041; DOI: https://doi.org/10.4049/jimmunol.166.12.7033
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  Liver-Derived DEC205⁺B220⁺CD19⁻ Dendritic Cells Regulate T Cell Responses

  Lina Lu, C. Andrew Bonham, Xiaoyan Liang, Zongyou Chen, Wei Li, Liangfu Wang, Simon C. Watkins, Michael A. Nalesnik, Mark S. Schlissel, Anthony J. Demestris, John J. Fung and Shiguang Qian

  J Immunol June 15, 2001, 166 (12) 7042-7052; DOI: https://doi.org/10.4049/jimmunol.166.12.7042
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  Aspirin Inhibits In Vitro Maturation and In Vivo Immunostimulatory Function of Murine Myeloid Dendritic Cells

  Holger Hackstein, Adrian E. Morelli, Adriana T. Larregina, Raymond W. Ganster, Glenn D. Papworth, Alison J. Logar, Simon C. Watkins, Louis D. Falo and Angus W. Thomson

  J Immunol June 15, 2001, 166 (12) 7053-7062; DOI: https://doi.org/10.4049/jimmunol.166.12.7053
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  TAP-Independent Presentation of CTL Epitopes by Trojan Antigens

  Jun Lu, Peter J. Wettstein, Yuichiro Higashimoto, Ettore Appella and Esteban Celis

  J Immunol June 15, 2001, 166 (12) 7063-7071; DOI: https://doi.org/10.4049/jimmunol.166.12.7063
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  IFN-γ Alters the Pathology of Graft Rejection: Protection from Early Necrosis

  Philip F. Halloran, Leslie W. Miller, Joan Urmson, Vido Ramassar, Lin-Fu Zhu, Norman M. Kneteman, Kim Solez and Marjan Afrouzian

  J Immunol June 15, 2001, 166 (12) 7072-7081; DOI: https://doi.org/10.4049/jimmunol.166.12.7072
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  Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs

  Alexander H. Dalpke, Sandra Opper, Stefan Zimmermann and Klaus Heeg

  J Immunol June 15, 2001, 166 (12) 7082-7089; DOI: https://doi.org/10.4049/jimmunol.166.12.7082
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  Cloning and Characterization of IL-22 Binding Protein, a Natural Antagonist of IL-10-Related T Cell-Derived Inducible Factor/IL-22

  Laure Dumoutier, Diane Lejeune, Didier Colau and Jean-Christophe Renauld

  J Immunol June 15, 2001, 166 (12) 7090-7095; DOI: https://doi.org/10.4049/jimmunol.166.12.7090
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  Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity

  Sergei V. Kotenko, Lara S. Izotova, Olga V. Mirochnitchenko, Elena Esterova, Harold Dickensheets, Raymond P. Donnelly and Sidney Pestka

  J Immunol June 15, 2001, 166 (12) 7096-7103; DOI: https://doi.org/10.4049/jimmunol.166.12.7096
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  Differential Regulation of Chemokine Gene Expression by 15-Deoxy-Δ^12,1412,14 Prostaglandin J₂

  Xia Zhang, Ji Ming Wang, Wang Hua Gong, Naofumi Mukaida and Howard A. Young

  J Immunol June 15, 2001, 166 (12) 7104-7111; DOI: https://doi.org/10.4049/jimmunol.166.12.7104
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  Opposite Regulation of Tissue Factor Expression by Calcineurin in Monocytes and Endothelial Cells

  Hans Hölschermann, Christine Rascher, Christian Oelschläger, Gerald Stapfer, Andreas Langenstein, Anne Staubitz, Ulrich Maus, Harald Tillmanns, Holger Bang and Werner Haberbosch

  J Immunol June 15, 2001, 166 (12) 7112-7120; DOI: https://doi.org/10.4049/jimmunol.166.12.7112
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  Augmentation of RANTES-Induced Extracellular Signal-Regulated Kinase Mediated Signaling and T Cell Adhesion by Elastase-Treated Fibronectin

  Alexander Brill, Rami Hershkoviz, Gayle G. Vaday, Yehuda Chowers and Ofer Lider

  J Immunol June 15, 2001, 166 (12) 7121-7127; DOI: https://doi.org/10.4049/jimmunol.166.12.7121
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  An Essential Role of the NF-κB/Toll-Like Receptor Pathway in Induction of Inflammatory and Tissue-Repair Gene Expression by Necrotic Cells

  Ming Li, David F. Carpio, Ye Zheng, Peter Bruzzo, Veena Singh, Fateh Ouaaz, Ruslan M. Medzhitov and Amer A. Beg

  J Immunol June 15, 2001, 166 (12) 7128-7135; DOI: https://doi.org/10.4049/jimmunol.166.12.7128
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  Mammalian and Viral IL-10 Enhance C-C Chemokine Receptor 5 but Down-Regulate C-C Chemokine Receptor 7 Expression by Myeloid Dendritic Cells: Impact on Chemotactic Responses and In Vivo Homing Ability

  Takuya Takayama, Adrian E. Morelli, Nobuyuki Onai, Motohiro Hirao, Kouji Matsushima, Hideaki Tahara and Angus W. Thomson

  J Immunol June 15, 2001, 166 (12) 7136-7143; DOI: https://doi.org/10.4049/jimmunol.166.12.7136
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  The Frequency of High Avidity T Cells Determines the Hierarchy of Determinant Spreading

  Jide Tian, Silvia Gregori, Luciano Adorini and Daniel L. Kaufman

  J Immunol June 15, 2001, 166 (12) 7144-7150; DOI: https://doi.org/10.4049/jimmunol.166.12.7144
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  Pharmacokinetic Differences Between a T Cell-Tolerizing and a T Cell-Activating Peptide

  Sanne Weijzen, Stephen C. Meredith, Markwin P. Velders, Amira G. Elmishad, Hans Schreiber and W. Martin Kast

  J Immunol June 15, 2001, 166 (12) 7151-7157; DOI: https://doi.org/10.4049/jimmunol.166.12.7151
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  Tolerance to Cyclosporin A-Induced Autologous Graft-Versus-Host Disease Is Mediated by a CD4⁺CD25⁺ Subset of Recent Thymic Emigrants

  Dianna Y. Wu and Irving Goldschneider

  J Immunol June 15, 2001, 166 (12) 7158-7164; DOI: https://doi.org/10.4049/jimmunol.166.12.7158
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  Sanglifehrin A, a Novel Cyclophilin-Binding Compound Showing Immunosuppressive Activity with a New Mechanism of Action

  Gerhard Zenke, Ulrike Strittmatter, Serge Fuchs, Valerie F. J. Quesniaux, Volker Brinkmann, Walter Schuler, Mauro Zurini, Albert Enz, Andreas Billich, Jean-Jacques Sanglier and Theo Fehr

  J Immunol June 15, 2001, 166 (12) 7165-7171; DOI: https://doi.org/10.4049/jimmunol.166.12.7165
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  The P2Y₁₁ Receptor Mediates the ATP-Induced Maturation of Human Monocyte-Derived Dendritic Cells

  Françoise Wilkin, Xavier Duhant, Catherine Bruyns, Nathalie Suarez-Huerta, Jean-Marie Boeynaems and Bernard Robaye

  J Immunol June 15, 2001, 166 (12) 7172-7177; DOI: https://doi.org/10.4049/jimmunol.166.12.7172
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  In Vivo-Matured Langerhans Cells Continue to Take Up and Process Native Proteins Unlike In Vitro-Matured Counterparts

  Christiane Ruedl, Pascale Koebel and Klaus Karjalainen

  J Immunol June 15, 2001, 166 (12) 7178-7182; DOI: https://doi.org/10.4049/jimmunol.166.12.7178
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  Progesterone Up-Regulates Anandamide Hydrolase in Human Lymphocytes: Role of Cytokines and Implications for Fertility

  Mauro Maccarrone, Herbert Valensise, Monica Bari, Natalia Lazzarin, Carlo Romanini and Alessandro Finazzi-Agrò

  J Immunol June 15, 2001, 166 (12) 7183-7189; DOI: https://doi.org/10.4049/jimmunol.166.12.7183
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  Production of TNF-α by Human Vγ9Vδ2 T Cells Via Engagement of FcγRIIIA, the Low Affinity Type 3 Receptor for the Fc Portion of IgG, Expressed upon TCR Activation by Nonpeptidic Antigen

  Virginie Lafont, Janny Liautard, Jean Pierre Liautard and Jean Favero

  J Immunol June 15, 2001, 166 (12) 7190-7199; DOI: https://doi.org/10.4049/jimmunol.166.12.7190
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  Differential Survival of Transferred CD8 T Cells and Host Reconstitution Depending on TCR Avidity for Host-Expressed Alloantigen

  Nathalie Auphan-Anezin and Anne-Marie Schmitt-Verhulst

  J Immunol June 15, 2001, 166 (12) 7200-7207; DOI: https://doi.org/10.4049/jimmunol.166.12.7200
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  CD45 Function Is Regulated by an Acidic 19-Amino Acid Insert in Domain II That Serves as a Binding and Phosphoacceptor Site for Casein Kinase 2

  Susanna F. Greer, Yan-ni Wang, Chander Raman and Louis B. Justement

  J Immunol June 15, 2001, 166 (12) 7208-7218; DOI: https://doi.org/10.4049/jimmunol.166.12.7208
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  Regulation of NK Cell-Mediated Cytotoxicity by the Adaptor Protein 3BP2

  Dragan Jevremovic, Daniel D. Billadeau, Renee A. Schoon, Christopher J. Dick and Paul J. Leibson

  J Immunol June 15, 2001, 166 (12) 7219-7228; DOI: https://doi.org/10.4049/jimmunol.166.12.7219
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  Quantitative Relationship Between MHC Class II-Superantigen Complexes and the Balance of T Cell Activation Versus Death

  Pascal M. Lavoie, Helen McGrath, Naglaa H. Shoukry, Pierre-André Cazenave, Rafick-Pierre Sékaly and Jacques Thibodeau

  J Immunol June 15, 2001, 166 (12) 7229-7237; DOI: https://doi.org/10.4049/jimmunol.166.12.7229
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  Processing of Immunosuppressive Pro-TGF-β1,2 by Human Glioblastoma Cells Involves Cytoplasmic and Secreted Furin-Like Proteases

  Jens Leitlein, Steffen Aulwurm, Robert Waltereit, Ulrike Naumann, Bettina Wagenknecht, Wolfgang Garten, Michael Weller and Michael Platten

  J Immunol June 15, 2001, 166 (12) 7238-7243; DOI: https://doi.org/10.4049/jimmunol.166.12.7238
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  Extrathymic Development of Vα11 T Cells in Placenta During Pregnancy and Their Possible Physiological Role

  Masahiko Yamasaki, Takahisa Sasho, Hideshige Moriya, Masamoto Kanno, Michishige Harada, Noriaki Kamada, Eiko Shimizu, Toshinori Nakayama and Masaru Taniguchi

  J Immunol June 15, 2001, 166 (12) 7244-7249; DOI: https://doi.org/10.4049/jimmunol.166.12.7244
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  Novel G Protein-Coupled Responses in Leukocytes Elicited by a Chemotactic Bacteriophage Displaying a Cell Type-Selective Binding Peptide

  David L. Jaye, Heather A. Edens, Luca Mazzucchelli and Charles A. Parkos

  J Immunol June 15, 2001, 166 (12) 7250-7259; DOI: https://doi.org/10.4049/jimmunol.166.12.7250
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  Recognition of HLA-Cw4 but Not HLA-Cw6 by the NK Cell Receptor Killer Cell Ig-Like Receptor Two-Domain Short Tail Number 4

  Gil Katz, Gal Markel, Sa’ar Mizrahi, Tal I. Arnon and Ofer Mandelboim

  J Immunol June 15, 2001, 166 (12) 7260-7267; DOI: https://doi.org/10.4049/jimmunol.166.12.7260
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  Factors Affecting the Efficiency of CD8⁺ T Cell Cross-Priming with Exogenous Antigens

  Holden T. Maecker, Smita A. Ghanekar, Maria A. Suni, Xiao-Song He, Louis J. Picker and Vernon C. Maino

  J Immunol June 15, 2001, 166 (12) 7268-7275; DOI: https://doi.org/10.4049/jimmunol.166.12.7268
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  Stat6 Is Necessary and Sufficient for IL-4’s Role in Th2 Differentiation and Cell Expansion

  Jinfang Zhu, Liying Guo, Cynthia J. Watson, Jane Hu-Li and William E. Paul

  J Immunol June 15, 2001, 166 (12) 7276-7281; DOI: https://doi.org/10.4049/jimmunol.166.12.7276
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  A Role for TGF-β in the Generation and Expansion of CD4⁺CD25⁺ Regulatory T Cells from Human Peripheral Blood

  Satoshi Yamagiwa, J. Dixon Gray, Shigeo Hashimoto and David A. Horwitz

  J Immunol June 15, 2001, 166 (12) 7282-7289; DOI: https://doi.org/10.4049/jimmunol.166.12.7282