The Journal of Immunology: 166 (10)

May 15, 2001; Volume 166,Issue 10

CUTTING EDGE

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Cutting Edge: FISP (IL-4-Induced Secreted Protein), a Novel Cytokine-Like Molecule Secreted by Th2 Cells
Gabriele Schaefer, Chandrasekar Venkataraman and Ulrike Schindler

J Immunol May 15, 2001, 166 (10) 5859-5863; DOI: https://doi.org/10.4049/jimmunol.166.10.5859
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Cutting Edge: Antigen-Independent CD8 T Cell Proliferation
Phillip Wong and Eric G. Pamer

J Immunol May 15, 2001, 166 (10) 5864-5868; DOI: https://doi.org/10.4049/jimmunol.166.10.5864
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Cutting Edge: A NK Complex-Linked Locus Governs Acute Versus Latent Herpes Simplex Virus Infection of Neurons
Rosemarie A. Pereira, Anthony Scalzo and Anthony Simmons

J Immunol May 15, 2001, 166 (10) 5869-5873; DOI: https://doi.org/10.4049/jimmunol.166.10.5869
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Cutting Edge: A Single MHC Anchor Residue Alters the Conformation of a Peptide-MHC Complex Inducing T Cells That Survive Negative Selection
Daniel A. Peterson, Richard J. DiPaolo, Osami Kanagawa and Emil R. Unanue

J Immunol May 15, 2001, 166 (10) 5874-5877; DOI: https://doi.org/10.4049/jimmunol.166.10.5874
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Cutting Edge: Systemic Inhibition of Angiogenesis Underlies Resistance to Tumors During Acute Toxoplasmosis
Christopher A. Hunter, Duonan Yu, Michael Gee, Cam V. Ngo, Cinzia Sevignani, Michael Goldschmidt, Tatyana V. Golovkina, Sydney Evans, William F. Lee and Andrei Thomas-Tikhonenko

J Immunol May 15, 2001, 166 (10) 5878-5881; DOI: https://doi.org/10.4049/jimmunol.166.10.5878

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Mycobacterium leprae-Specific, HLA Class II-Restricted Killing of Human Schwann Cells by CD4⁺ Th1 Cells: A Novel Immunopathogenic Mechanism of Nerve Damage in Leprosy
Eric Spierings, Tjitske de Boer, Brigitte Wieles, Linda B. Adams, Enrico Marani and Tom H. M. Ottenhoff

J Immunol May 15, 2001, 166 (10) 5883-5888; DOI: https://doi.org/10.4049/jimmunol.166.10.5883
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CD44-Deficient Mice Exhibit Enhanced Hepatitis After Concanavalin A Injection: Evidence for Involvement of CD44 in Activation-Induced Cell Death
Dawei Chen, Robert J. McKallip, Ahmet Zeytun, Yoonkyung Do, Catherine Lombard, John L. Robertson, Tak W. Mak, Prakash S. Nagarkatti and Mitzi Nagarkatti

J Immunol May 15, 2001, 166 (10) 5889-5897; DOI: https://doi.org/10.4049/jimmunol.166.10.5889
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Distinct Mechanisms Contribute to Generate and Change the CD4:CD8 Cell Ratio During Thymus Development: A Role for the Notch Ligand, Jagged1
Eva Jiménez, Angeles Vicente, Rosa Sacedón, Juan J. Muñoz, Gerry Weinmaster, Agustín G. Zapata and Alberto Varas

J Immunol May 15, 2001, 166 (10) 5898-5908; DOI: https://doi.org/10.4049/jimmunol.166.10.5898
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Requirement for Leptin in the Induction and Progression of Autoimmune Encephalomyelitis
Giuseppe Matarese, Antonio Di Giacomo, Veronica Sanna, Graham M. Lord, Jane K. Howard, Antonino Di Tuoro, Stephen R. Bloom, Robert I. Lechler, Serafino Zappacosta and Silvia Fontana

J Immunol May 15, 2001, 166 (10) 5909-5916; DOI: https://doi.org/10.4049/jimmunol.166.10.5909
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Human Dendritic Cells Are Activated by Chimeric Human Papillomavirus Type-16 Virus-Like Particles and Induce Epitope-Specific Human T Cell Responses In Vitro
Michael P. Rudolf, Steven C. Fausch, Diane M. Da Silva and W. Martin Kast

J Immunol May 15, 2001, 166 (10) 5917-5924; DOI: https://doi.org/10.4049/jimmunol.166.10.5917
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Distinct BMI-1 and EZH2 Expression Patterns in Thymocytes and Mature T Cells Suggest a Role for Polycomb Genes in Human T Cell Differentiation
Frank M. Raaphorst, Arie P. Otte, Folkert J. van Kemenade, Tjasso Blokzijl, Elly Fieret, Karien M. Hamer, David P. E. Satijn and Chris J. L. M. Meijer

J Immunol May 15, 2001, 166 (10) 5925-5934; DOI: https://doi.org/10.4049/jimmunol.166.10.5925
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Definition of a Novel Cellular Constituent of the Bone Marrow That Regulates the Response of Immature B Cells to B Cell Antigen Receptor Engagement
Peter C. Sandel, Mariya Gendelman, Garnett Kelsoe and John G. Monroe

J Immunol May 15, 2001, 166 (10) 5935-5944; DOI: https://doi.org/10.4049/jimmunol.166.10.5935
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A Requirement for IL-2/IL-2 Receptor Signaling in Intrathymic Negative Selection
Hamid Bassiri and Simon R. Carding

J Immunol May 15, 2001, 166 (10) 5945-5954; DOI: https://doi.org/10.4049/jimmunol.166.10.5945
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Protein Kinase C-θ Mediates a Selective T Cell Survival Signal Via Phosphorylation of BAD
Martin Villalba, Paul Bushway and Amnon Altman

J Immunol May 15, 2001, 166 (10) 5955-5963; DOI: https://doi.org/10.4049/jimmunol.166.10.5955
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Generation of Macrophages from Early T Progenitors In Vitro
Chong-Kil Lee, Jeong Ki Kim, Youngsoo Kim, Myung-Koo Lee, Kyungjae Kim, Jong-Koo Kang, Robert Hofmeister, Scott K. Durum and Seong Sun Han

J Immunol May 15, 2001, 166 (10) 5964-5969; DOI: https://doi.org/10.4049/jimmunol.166.10.5964
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Murine IL-10 Gene Transfer Inhibits Established Collagen-Induced Arthritis and Reduces Adenovirus-Mediated Inflammatory Responses in Mouse Liver
Emilia Quattrocchi, Margaret J. Dallman, Amar P. Dhillon, Alberto Quaglia, Gianfilippo Bagnato and Marc Feldmann

J Immunol May 15, 2001, 166 (10) 5970-5978; DOI: https://doi.org/10.4049/jimmunol.166.10.5970
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Inhibition of Antigen-Induced Mediator Release from IgE-Sensitized Cells by a Monoclonal Anti-FcεRI α-Chain Receptor Antibody: Implications for the Involvement of the Membrane-Proximal α-Chain Region in FcεRI-Mediated Cell Activation
Andreas Nechansky, Michael W. Robertson, Bettina A. Albrecht, John R. Apgar and Franz Kricek

J Immunol May 15, 2001, 166 (10) 5979-5990; DOI: https://doi.org/10.4049/jimmunol.166.10.5979
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Early Intestinal Th1 Inflammation and Mucosal T Cell Recruitment During Acute Graft-Versus-Host Reaction
Denis Snider and Hong Liang

J Immunol May 15, 2001, 166 (10) 5991-5999; DOI: https://doi.org/10.4049/jimmunol.166.10.5991
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Histamine Induces CD86 Expression and Chemokine Production by Human Immature Dendritic Cells
Gersende Caron, Yves Delneste, Edith Roelandts, Catherine Duez, Nathalie Herbault, Giovanni Magistrelli, Jean-Yves Bonnefoy, Joel Pestel and Pascale Jeannin

J Immunol May 15, 2001, 166 (10) 6000-6006; DOI: https://doi.org/10.4049/jimmunol.166.10.6000
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An IFN-γ-Dependent Pathway Controls Stimulation of Memory Phenotype CD8⁺ T Cell Turnover In Vivo by IL-12, IL-18, and IFN-γ
David F. Tough, Xiaohong Zhang and Jonathan Sprent

J Immunol May 15, 2001, 166 (10) 6007-6011; DOI: https://doi.org/10.4049/jimmunol.166.10.6007
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Differential Regulation of Th1 and Th2 Functions of NKT Cells by CD28 and CD40 Costimulatory Pathways
Yoshihiro Hayakawa, Kazuyoshi Takeda, Hideo Yagita, Luc Van Kaer, Ikuo Saiki and Ko Okumura

J Immunol May 15, 2001, 166 (10) 6012-6018; DOI: https://doi.org/10.4049/jimmunol.166.10.6012
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Signaling Through MHC Class II Molecules Blocks CD95-Induced Apoptosis
Ian M. Catlett, Ping Xie, Bruce S. Hostager and Gail A. Bishop

J Immunol May 15, 2001, 166 (10) 6019-6024; DOI: https://doi.org/10.4049/jimmunol.166.10.6019
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Involvement of Bik, a Proapoptotic Member of the Bcl-2 Family, in Surface IgM-Mediated B Cell Apoptosis
Aimin Jiang and Edward A. Clark

J Immunol May 15, 2001, 166 (10) 6025-6033; DOI: https://doi.org/10.4049/jimmunol.166.10.6025
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CD45 Tyrosine Phosphatase Controls Common γ-Chain Cytokine-Mediated STAT and Extracellular Signal-Related Kinase Phosphorylation in Activated Human Lymphoblasts: Inhibition of Proliferation Without Induction of Apoptosis
Norbert Blank, Martin Kriegel, Thomas Hieronymus, Thomas Geiler, Silke Winkler, Joachim R. Kalden and Hanns-Martin Lorenz

J Immunol May 15, 2001, 166 (10) 6034-6040; DOI: https://doi.org/10.4049/jimmunol.166.10.6034
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B Cell Immunodeficiency Fails to Develop in CD4-Deficient Mice Infected with BM5: Murine AIDS as a Multistep Disease
David P. Harris, Susanne Koch, Lina M. Mullen and Susan L. Swain

J Immunol May 15, 2001, 166 (10) 6041-6049; DOI: https://doi.org/10.4049/jimmunol.166.10.6041
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Requirement for a Complex Array of Costimulators in the Negative Selection of Autoreactive Thymocytes In Vivo
Ruixia Li and Dawne M. Page

J Immunol May 15, 2001, 166 (10) 6050-6056; DOI: https://doi.org/10.4049/jimmunol.166.10.6050
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Recombinant Allergens with Reduced Allergenicity but Retaining Immunogenicity of the Natural Allergens: Hybrids of Yellow Jacket and Paper Wasp Venom Allergen Antigen 5s
Te Piao King, Sui Y. Jim, Rafael I. Monsalve, Anne Kagey-Sobotka, Lawrence M. Lichtenstein and Michael D. Spangfort

J Immunol May 15, 2001, 166 (10) 6057-6065; DOI: https://doi.org/10.4049/jimmunol.166.10.6057
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Development of Intestinal Intraepithelial Lymphocytes, NK Cells, and NK 1.1⁺ T Cells in CD45-Deficient Mice
Steven M. Martin, Indira K. Mehta, Wayne M. Yokoyama, Matthew L. Thomas and Robin G. Lorenz

J Immunol May 15, 2001, 166 (10) 6066-6073; DOI: https://doi.org/10.4049/jimmunol.166.10.6066
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CD8⁺ Tumor-Infiltrating Lymphocytes Are Primed for Fas-Mediated Activation-Induced Cell Death But Are Not Apoptotic In Situ
Sasa Radoja, Masanao Saio and Alan B. Frey

J Immunol May 15, 2001, 166 (10) 6074-6083; DOI: https://doi.org/10.4049/jimmunol.166.10.6074
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p27^kif Protein Levels and E2F Activity Are Targets of Cot Kinase During G₁ Phase Progression in T Cells
Ana Velasco-Sampayo and Susana Alemany

J Immunol May 15, 2001, 166 (10) 6084-6090; DOI: https://doi.org/10.4049/jimmunol.166.10.6084
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Role for Transcription Pax5A Factor in Maintaining Commitment to the B Cell Lineage by Selective Inhibition of Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression
Mark Y. Chiang and John G. Monroe

J Immunol May 15, 2001, 166 (10) 6091-6098; DOI: https://doi.org/10.4049/jimmunol.166.10.6091
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Cell-Associated Ovalbumin Is Cross-Presented Much More Efficiently than Soluble Ovalbumin In Vivo
Ming Li, Gayle M. Davey, Robyn M. Sutherland, Christian Kurts, Andrew M. Lew, Claire Hirst, Francis R. Carbone and William R. Heath

J Immunol May 15, 2001, 166 (10) 6099-6103; DOI: https://doi.org/10.4049/jimmunol.166.10.6099

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Stage-Specific Modulation of IFN-Regulatory Factor 4 Function by Krüppel-Type Zinc Finger Proteins
Sanjay Gupta, Alissa Anthony and Alessandra B. Pernis

J Immunol May 15, 2001, 166 (10) 6104-6111; DOI: https://doi.org/10.4049/jimmunol.166.10.6104
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Increasing the Affinity for Tumor Antigen Enhances Bispecific Antibody Cytotoxicity
Adrian M. McCall, Lillian Shahied, Anne R. Amoroso, Eva M. Horak, Heidi H. Simmons, Ulrick Nielson, Gregory P. Adams, Robert Schier, James D. Marks and Louis M. Weiner

J Immunol May 15, 2001, 166 (10) 6112-6117; DOI: https://doi.org/10.4049/jimmunol.166.10.6112
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Lupus Antibody Bivalency Is Required to Enhance Prothrombin Binding to Phospholipid
Susan L. Field, Colin N. Chesterman, Yan-Ping Dai and Philip J. Hogg

J Immunol May 15, 2001, 166 (10) 6118-6125; DOI: https://doi.org/10.4049/jimmunol.166.10.6118
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Fundamental Ca²⁺ Signaling Mechanisms in Mouse Dendritic Cells: CRAC Is the Major Ca²⁺ Entry Pathway
Shyue-fang Hsu, Peta J. O’Connell, Vitaly A. Klyachko, Michael N. Badminton, Angus W. Thomson, Meyer B. Jackson, David E. Clapham and Gerard P. Ahern

J Immunol May 15, 2001, 166 (10) 6126-6133; DOI: https://doi.org/10.4049/jimmunol.166.10.6126
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Transcriptional Regulation of CD28 Expression by CD28GR, a Novel Promoter Element Located in Exon 1 of the CD28 Gene
Catherine J. Lin and Robert C. Tam

J Immunol May 15, 2001, 166 (10) 6134-6143; DOI: https://doi.org/10.4049/jimmunol.166.10.6134
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The Exon A (C77G) Mutation Is a Common Cause of Abnormal CD45 Splicing in Humans
Elma Z. Tchilian, Diana L. Wallace, Nesrina Imami, Hua-Xin Liao, Catherine Burton, Frances Gotch, Jeremy Martinson, Barton F. Haynes and Peter C. L. Beverley

J Immunol May 15, 2001, 166 (10) 6144-6148; DOI: https://doi.org/10.4049/jimmunol.166.10.6144
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Transcriptional Regulation of Intracellular IL-1 Receptor Antagonist Gene by IL-1α in Primary Mouse Keratinocytes
Eunhye La and Susan M. Fischer

J Immunol May 15, 2001, 166 (10) 6149-6155; DOI: https://doi.org/10.4049/jimmunol.166.10.6149
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Multiple Transcription Factors Regulate the Inducible Expression of the Human Complement Receptor 2 Promoter
Lyudmila A. Vereshchagina, Mate Tolnay and George C. Tsokos

J Immunol May 15, 2001, 166 (10) 6156-6163; DOI: https://doi.org/10.4049/jimmunol.166.10.6156
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Characteristics of HIV-1 Nef Regions Containing Multiple CD8⁺ T Cell Epitopes: Wealth of HLA-Binding Motifs and Sensitivity to Proteasome Degradation
Jeannine Choppin, William Cohen, Alberto Bianco, Jean-Paul Briand, Francine Connan, Marc Dalod and Jean-Gérard Guillet

J Immunol May 15, 2001, 166 (10) 6164-6169; DOI: https://doi.org/10.4049/jimmunol.166.10.6164
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RNA-Dependent Protein Kinase PKR Is Required for Activation of NF-κB by IFN-γ in a STAT1-Independent Pathway
Amitabha Deb, S. Jaharul Haque, Trine Mogensen, Robert H. Silverman and Bryan R. G. Williams

J Immunol May 15, 2001, 166 (10) 6170-6180; DOI: https://doi.org/10.4049/jimmunol.166.10.6170
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Positive and Negative Roles of the Trans-Acting T Cell Factor-1 for the Acquisition of Distinct Ly-49 MHC Class I Receptors by NK Cells
Béatrice Kunz and Werner Held

J Immunol May 15, 2001, 166 (10) 6181-6187; DOI: https://doi.org/10.4049/jimmunol.166.10.6181
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A Prominent Role for Activator Protein-1 in the Transcription of the Human 2B4 (CD244) Gene in NK Cells
Samuel S. Chuang, Hoang-Tuan K. Pham, Pappanaicken R. Kumaresan and Porunelloor A. Mathew

J Immunol May 15, 2001, 166 (10) 6188-6195; DOI: https://doi.org/10.4049/jimmunol.166.10.6188
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Characterization of Mouse Carboxypeptidase N Small Active Subunit Gene Structure
Kirstin W. Matthews and Rick A. Wetsel

J Immunol May 15, 2001, 166 (10) 6196-6202; DOI: https://doi.org/10.4049/jimmunol.166.10.6196

HOST DEFENSE

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Culture at High Density Improves the Ability of Human Macrophages to Control Mycobacterial Growth
Neio Boechat, Francine Bouchonnet, Marcel Bonay, Alain Grodet, Vladimir Pelicic, Brigitte Gicquel and Allan J. Hance

J Immunol May 15, 2001, 166 (10) 6203-6211; DOI: https://doi.org/10.4049/jimmunol.166.10.6203
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Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy
Steve Gyorffy, Kay Palmer, Thomas J. Podor, Mary Hitt and Jack Gauldie

J Immunol May 15, 2001, 166 (10) 6212-6217; DOI: https://doi.org/10.4049/jimmunol.166.10.6212
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Enhancement of Sindbis Virus Self-Replicating RNA Vaccine Potency by Linkage of Mycobacterium tuberculosis Heat Shock Protein 70 Gene to an Antigen Gene
Wen-Fang Cheng, Chien-Fu Hung, Chee-Yin Chai, Keng-Fu Hsu, Liangmai He, Charles M. Rice, Morris Ling and T.-C. Wu

J Immunol May 15, 2001, 166 (10) 6218-6226; DOI: https://doi.org/10.4049/jimmunol.166.10.6218
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Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with Mycobacterium tuberculosis
Rhea N. Coler, Antonio Campos-Neto, Pamela Ovendale, Fiona H. Day, Steven P. Fling, Liqing Zhu, Natalya Serbina, JoAnne L. Flynn, Steven G. Reed and Mark R. Alderson

J Immunol May 15, 2001, 166 (10) 6227-6235; DOI: https://doi.org/10.4049/jimmunol.166.10.6227
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A Critical Role of Fc Receptor-Mediated Antibody-Dependent Phagocytosis in the Host Resistance to Blood-Stage Plasmodium berghei XAT Infection
Toshihiko Yoneto, Seiji Waki, Toshihiro Takai, Yoh-ichi Tagawa, Yoichiro Iwakura, Junichiro Mizuguchi, Hideo Nariuchi and Takayuki Yoshimoto

J Immunol May 15, 2001, 166 (10) 6236-6241; DOI: https://doi.org/10.4049/jimmunol.166.10.6236
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Herpes Simplex Inhibits the Capacity of Lymphoblastoid B Cell Lines to Stimulate CD4⁺ T Cells
Serge Barcy and Lawrence Corey

J Immunol May 15, 2001, 166 (10) 6242-6249; DOI: https://doi.org/10.4049/jimmunol.166.10.6242
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Activity of Human IgG and IgA Subclasses in Immune Defense Against Neisseria meningitidis Serogroup B
Gestur Vidarsson, W.-Ludo van der Pol, Jean M. H. van den Elsen, Henriëtte Vilé, Marc Jansen, Jacques Duijs, H. Craig Morton, Edwin Boel, Mohamed R. Daha, Blaise Corthésy and Jan G. J. van de Winkel

J Immunol May 15, 2001, 166 (10) 6250-6256; DOI: https://doi.org/10.4049/jimmunol.166.10.6250
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Secretory IgA Specific for a Conserved Epitope on gp41 Envelope Glycoprotein Inhibits Epithelial Transcytosis of HIV-1
Annette Alfsen, Pierre Iniguez, Edwige Bouguyon and Morgane Bomsel

J Immunol May 15, 2001, 166 (10) 6257-6265; DOI: https://doi.org/10.4049/jimmunol.166.10.6257
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Extrafollicular Plasmablast B Cells Play a Key Role in Carrying Retroviral Infection to Peripheral Organs
Daniela Finke, Frédéric Baribaud, Heidi Diggelmann and Hans Acha-Orbea

J Immunol May 15, 2001, 166 (10) 6266-6275; DOI: https://doi.org/10.4049/jimmunol.166.10.6266
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ATP-Mediated Killing of Mycobacterium bovis Bacille Calmette-Guérin Within Human Macrophages Is Calcium Dependent and Associated with the Acidification of Mycobacteria-Containing Phagosomes
Carmel B. Stober, David A. Lammas, Cheuk M. Li, Dinikantha S. Kumararatne, Stafford L. Lightman and Craig A. McArdle

J Immunol May 15, 2001, 166 (10) 6276-6286; DOI: https://doi.org/10.4049/jimmunol.166.10.6276

INFLAMMATION

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Cell Density Regulates Neutrophil IL-8 Synthesis: Role of IL-1 Receptor Antagonist and Soluble TNF Receptors
Katja Hattar, Ludger Fink, Karin Fietzner, Barbara Himmel, Friedrich Grimminger, Werner Seeger and Ulf Sibelius

J Immunol May 15, 2001, 166 (10) 6287-6293; DOI: https://doi.org/10.4049/jimmunol.166.10.6287
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A Potential Role for Annexin 1 as a Physiologic Mediator of Glucocorticoid-Induced L-Selectin Shedding from Myeloid Cells
Holly J. Strausbaugh and Steven D. Rosen

J Immunol May 15, 2001, 166 (10) 6294-6300; DOI: https://doi.org/10.4049/jimmunol.166.10.6294
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Reactive Nitrogen Species Inhibit Alveolar Epithelial Fluid Transport After Hemorrhagic Shock in Rats
Jean-François Pittet, Le N. Lu, David G. Morris, Kathrin Modelska, William J. Welch, Hannah V. Carey, Jeremie Roux and Michael A. Matthay

J Immunol May 15, 2001, 166 (10) 6301-6310; DOI: https://doi.org/10.4049/jimmunol.166.10.6301
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Role of p190RhoGAP in β₂ Integrin Regulation of RhoA in Human Neutrophils
Karim Dib, Fredrik Melander and Tommy Andersson

J Immunol May 15, 2001, 166 (10) 6311-6322; DOI: https://doi.org/10.4049/jimmunol.166.10.6311
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IL-10-Deficient Mice Demonstrate Multiple Organ Failure and Increased Mortality During Escherichia coli Peritonitis Despite an Accelerated Bacterial Clearance
Miguel E. Sewnath, Dariusz P. Olszyna, Rakesh Birjmohun, Fiebo J. W. ten Kate, Dirk J. Gouma and Tom van der Poll

J Immunol May 15, 2001, 166 (10) 6323-6331; DOI: https://doi.org/10.4049/jimmunol.166.10.6323
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Antioxidants Inhibit Indoleamine 2,3-Dioxygenase in IFN-γ-Activated Human Macrophages: Posttranslational Regulation by Pyrrolidine Dithiocarbamate
Shane R. Thomas, Houta Salahifar, Ryuichi Mashima, Nicholas H. Hunt, Des R. Richardson and Roland Stocker

J Immunol May 15, 2001, 166 (10) 6332-6340; DOI: https://doi.org/10.4049/jimmunol.166.10.6332
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Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models
Robert S. Ames, Dennis Lee, James J. Foley, Anthony J. Jurewicz, Mark A. Tornetta, Wilfried Bautsch, Britta Settmacher, Andreas Klos, Karl F. Erhard, Russell D. Cousins, Anthony C. Sulpizio, J. Paul Hieble, Gerald McCafferty, Keith W. Ward, Jerry L. Adams, William E. Bondinell, David C. Underwood, Ruth R. Osborn, Alison M. Badger and Henry M. Sarau

J Immunol May 15, 2001, 166 (10) 6341-6348; DOI: https://doi.org/10.4049/jimmunol.166.10.6341
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Phosphorylation of the Activation Loop of γ p21-Activated Kinase (γ-Pak) and Related Kinases (MSTs) in Normal and Stressed Neutrophils
Jian P. Lian, Alex Toker and John A. Badwey

J Immunol May 15, 2001, 166 (10) 6349-6357; DOI: https://doi.org/10.4049/jimmunol.166.10.6349
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IL-10 Up-Regulates Macrophage Expression of the S100 Protein S100A8
Ken Xu, Tina Yen and Carolyn L. Geczy

J Immunol May 15, 2001, 166 (10) 6358-6366; DOI: https://doi.org/10.4049/jimmunol.166.10.6358
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Mycobacterium bovis Strain Bacillus Calmette-Guérin-Induced Liver Granulomas Contain a Diverse TCR Repertoire, but a Monoclonal T Cell Population Is Sufficient for Protective Granuloma Formation
Laura H. Hogan, Khen Macvilay, Brittany Barger, Dominic Co, Irena Malkovska, Glenn Fennelly and Matyas Sandor

J Immunol May 15, 2001, 166 (10) 6367-6375; DOI: https://doi.org/10.4049/jimmunol.166.10.6367
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Surfactant Protein A Suppresses Lipopolysaccharide-Induced IL-10 Production by Murine Macrophages
Laurent Salez, Viviane Balloy, Nico van Rooijen, Mai Lebastard, Lhousseine Touqui, Francis X. McCormack and Michel Chignard

J Immunol May 15, 2001, 166 (10) 6376-6382; DOI: https://doi.org/10.4049/jimmunol.166.10.6376
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ATP Mediates Calcium Signaling Between Astrocytes and Microglial Cells: Modulation by IFN-γ
Claudia Verderio and Michela Matteoli

J Immunol May 15, 2001, 166 (10) 6383-6391; DOI: https://doi.org/10.4049/jimmunol.166.10.6383
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IL-18 Gene Transfer by Adenovirus Prevents the Development of and Reverses Established Allergen-Induced Airway Hyperreactivity
David M. Walter, Carmen P. Wong, Rosemarie H. DeKruyff, Gerald J. Berry, Shoshana Levy and Dale T. Umetsu

J Immunol May 15, 2001, 166 (10) 6392-6398; DOI: https://doi.org/10.4049/jimmunol.166.10.6392

CLINICAL IMMUNOLOGY

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Apoptosis: One of the Mechanisms That Maintains Unresponsiveness of the Intestinal Mucosal Immune System
Ping Bu, Ali Keshavarzian, David D. Stone, Jianzhong Liu, Phong T. Le, Susan Fisher and Liang Qiao

J Immunol May 15, 2001, 166 (10) 6399-6403; DOI: https://doi.org/10.4049/jimmunol.166.10.6399
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A Novel Serum Protein That Is Selectively Produced by Cytotoxic Lymphocytes
Kazuyuki Ogawa, Kazuya Tanaka, Akira Ishii, Yoshiko Nakamura, Shigemi Kondo, Kazuo Sugamura, Shoichi Takano, Masataka Nakamura and Kinya Nagata

J Immunol May 15, 2001, 166 (10) 6404-6412; DOI: https://doi.org/10.4049/jimmunol.166.10.6404
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Genetic Regulation of Autoimmune Disease: BALB/c Background TGF-β1-Deficient Mice Develop Necroinflammatory IFN-γ-Dependent Hepatitis
James D. Gorham, Jack T. Lin, James L. Sung, Lynnie A. Rudner and Margaret A. French

J Immunol May 15, 2001, 166 (10) 6413-6422; DOI: https://doi.org/10.4049/jimmunol.166.10.6413
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Calreticulin, a Potential Cell Surface Receptor Involved in Cell Penetration of Anti-DNA Antibodies
Nabila Seddiki, Farida Nato, Pierre Lafaye, Zahir Amoura, Jean Charles Piette and Jean Claude Mazié

J Immunol May 15, 2001, 166 (10) 6423-6429; DOI: https://doi.org/10.4049/jimmunol.166.10.6423
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Anti-CTLA-4 Antibody Treatment Triggers Determinant Spreading and Enhances Murine Myasthenia Gravis
Hua-Bing Wang, Fu-Dong Shi, Hulun Li, Benedict J. Chambers, Hans Link and Hans-Gustaf Ljunggren

J Immunol May 15, 2001, 166 (10) 6430-6436; DOI: https://doi.org/10.4049/jimmunol.166.10.6430
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Nonproliferating Bystander CD4⁺ T Cells Lacking Activation Markers Support HIV Replication During Immune Activation
David Scales, Houping Ni, Farida Shaheen, John Capodici, Georgetta Cannon and Drew Weissman

J Immunol May 15, 2001, 166 (10) 6437-6443; DOI: https://doi.org/10.4049/jimmunol.166.10.6437
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Complement Component C3 Is Not Required for Full Expression of Immune Complex Glomerulonephritis in MRL/lpr Mice
Hideharu Sekine, Christopher M. Reilly, Ivan D. Molano, Gérard Garnier, Antonella Circolo, Philip Ruiz, V. Michael Holers, Susan A. Boackle and Gary S. Gilkeson

J Immunol May 15, 2001, 166 (10) 6444-6451; DOI: https://doi.org/10.4049/jimmunol.166.10.6444
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Impairment of CD8⁺ T Suppressor Cell Function in Patients with Active Systemic Lupus Erythematosus
Gilberto Filaci, Sabrina Bacilieri, Marco Fravega, Monia Monetti, Paola Contini, Massimo Ghio, Maurizio Setti, Francesco Puppo and Francesco Indiveri

J Immunol May 15, 2001, 166 (10) 6452-6457; DOI: https://doi.org/10.4049/jimmunol.166.10.6452

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Table of Contents

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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