The Journal of Immunology: 161 (9)

November 1, 1998; Volume 161,Issue 9

CUTTING EDGE

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Cutting Edge: CpG DNA Is a Potent Enhancer of Systemic and Mucosal Immune Responses Against Hepatitis B Surface Antigen with Intranasal Administration to Mice
Michael J. McCluskie and Heather L. Davis

J Immunol November 1, 1998, 161 (9) 4463-4466;
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Cutting Edge: Bystander Apoptosis Triggers Dendritic Cell Maturation and Antigen-Presenting Function
Patrizia Rovere, Cristina Vallinoto, Attilio Bondanza, Maria Cristina Crosti, Maria Rescigno, Paola Ricciardi-Castagnoli, Claudio Rugarli and Angelo A. Manfredi

J Immunol November 1, 1998, 161 (9) 4467-4471;
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Cutting Edge: Senescent BALB/c Mice Exhibit Decreased Expression of λ5 Surrogate Light Chains and Reduced Development Within the Pre-B Cell Compartment
Erin M. Sherwood, Bonnie B. Blomberg, Wei Xu, Cynthia A. Warner and Richard L. Riley

J Immunol November 1, 1998, 161 (9) 4472-4475;
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Cutting Edge: Antigen-Specific T Lymphocytes Regulate Lipopolysaccharide-Induced Apoptosis of Dendritic Cells In Vivo
Thibaut De Smedt, Bernard Pajak, Gerry G. B. Klaus, Randolph J. Noelle, Jacques Urbain, Oberdan Leo and Muriel Moser

J Immunol November 1, 1998, 161 (9) 4476-4479;
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Cutting Edge: B Cell-Deficient Mice Develop Experimental Allergic Encephalomyelitis with Demyelination After Myelin Oligodendrocyte Glycoprotein Sensitization
Peter Hjelmström, Amy E. Juedes, Jenny Fjell and Nancy H. Ruddle

J Immunol November 1, 1998, 161 (9) 4480-4483;
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Cutting Edge: Chemotactic Activity of Soluble Fas Ligand Against Phagocytes
Ken-ichiro Seino, Kazuhisa Iwabuchi, Nobuhiko Kayagaki, Ryukou Miyata, Isao Nagaoka, Akio Matsuzawa, Katashi Fukao, Hideo Yagita and Ko Okumura

J Immunol November 1, 1998, 161 (9) 4484-4488;
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Cutting Edge: Thymic Positive Selection and Peripheral Activation of Islet Antigen-Specific T Cells: Separation of Two Diabetogenic Steps by an I-A^g7 Class II MHC β-Chain Mutant
Osami Kanagawa, Barbara A. Vaupel, Guan Xu, Emil R. Unanue and Jonathan D. Katz

J Immunol November 1, 1998, 161 (9) 4489-4492;
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Cutting Edge: Rapid Induction of Mitogen-Activated Protein Kinases by Immune Stimulatory CpG DNA
Ae-Kyung Yi and Arthur M. Krieg

J Immunol November 1, 1998, 161 (9) 4493-4497;

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Immunodominance in the CTL Response Against Minor Histocompatibility Antigens: Interference Between Responding T Cells, Rather than with Presentation of Epitopes
Elisabeth Z. Wolpert, Per Grufman, Johan K. Sandberg, Anna Tegnesjö and Klas Kärre

J Immunol November 1, 1998, 161 (9) 4499-4505;
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Uncoupling Activation-Dependent HS1 Phosphorylation from Nuclear Factor of Activated T Cells Transcriptional Activation in Jurkat T Cells: Differential Signaling Through CD3 and the Costimulatory Receptors CD2 and CD28
Jill E. Hutchcroft, Jacqueline M. Slavik, Huamao Lin, Takeshi Watanabe and Barbara E. Bierer

J Immunol November 1, 1998, 161 (9) 4506-4512;
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Self-Restricted Dual Receptor Memory T Cells
William T. Lee, Vaibhavi Shiledar-Baxi, Gary M. Winslow, Denise Mix and Donal B. Murphy

J Immunol November 1, 1998, 161 (9) 4513-4519;
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Dendritic Cell Immunization Breaks Cytotoxic T Lymphocyte Tolerance in Hepatitis B Virus Transgenic Mice
Yukihiro Shimizu, Luca G. Guidotti, Patricia Fowler and Francis V. Chisari

J Immunol November 1, 1998, 161 (9) 4520-4529;
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Longitudinal Analysis of the Acute Sendai Virus-Specific CD4⁺ T Cell Response and Memory
David J. Topham and Peter C. Doherty

J Immunol November 1, 1998, 161 (9) 4530-4535;
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Expression and Function of Fas on Cells Damaged by γ-Irradiation in B6 and B6/lpr Mice
Jessica K. Booker, Elizabeth A. Reap and Philip L. Cohen

J Immunol November 1, 1998, 161 (9) 4536-4541;
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The Rate of Dissociation Between Antibody and Antigen Determines the Efficiency of Antibody-Mediated Antigen Presentation to T Cells
Pierre Guermonprez, Patrick England, Hugues Bedouelle and Claude Leclerc

J Immunol November 1, 1998, 161 (9) 4542-4548;
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Evidence for an Important Interaction Between a Complement-Derived CD21 Ligand on Follicular Dendritic Cells and CD21 on B Cells in the Initiation of IgG Responses
Dahui Qin, Jiuhua Wu, Michael C. Carroll, Gregory F. Burton, Andras K. Szakal and John G. Tew

J Immunol November 1, 1998, 161 (9) 4549-4554;
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Autoimmunity Develops in Lupus-Prone NZB Mice Despite Normal T Cell Tolerance
Joan Wither and Brian Vukusic

J Immunol November 1, 1998, 161 (9) 4555-4562;
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CD40 Ligand/Trimer DNA Enhances Both Humoral and Cellular Immune Responses and Induces Protective Immunity to Infectious and Tumor Challenge
Sanjay Gurunathan, Kari R. Irvine, Chang-You Wu, Jeffrey I. Cohen, Elaine Thomas, Calman Prussin, Nicholas P. Restifo and Robert A. Seder

J Immunol November 1, 1998, 161 (9) 4563-4571;
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Adenovirus-Mediated Expression of a Dominant Negative Mutant of p65/RelA Inhibits Proinflammatory Gene Expression in Endothelial Cells Without Sensitizing to Apoptosis
Miguel P. Soares, Ashok Muniappan, Elzbieta Kaczmarek, Katarzyna Koziak, Christopher J. Wrighton, Florence Steinhäuslin, Christiane Ferran, Hans Winkler, Fritz H. Bach and Josef Anrather

J Immunol November 1, 1998, 161 (9) 4572-4582;
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CD40 Ligand Is Pivotal to Efficient Control of Virus Replication in Mice Infected with Lymphocytic Choriomeningitis Virus
A. Randrup Thomsen, A. Nansen, J. Pravsgaard Christensen, S. Ørding Andreasen and O. Marker

J Immunol November 1, 1998, 161 (9) 4583-4590;
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A Mouse Carrying Genetic Defect in the Choice Between T and B Lymphocytes
Yayoi Tokoro, Takehiko Sugawara, Hiroyuki Yaginuma, Hiromitsu Nakauchi, Cox Terhorst, Baoping Wang and Yousuke Takahama

J Immunol November 1, 1998, 161 (9) 4591-4598;
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Recombinant Rat Surfactant-Associated Protein D Inhibits Human T Lymphocyte Proliferation and IL-2 Production
Paul J. Borron, Erika C. Crouch, James F. Lewis, Jo Rae Wright, Fred Possmayer and Laurence J. Fraher

J Immunol November 1, 1998, 161 (9) 4599-4603;
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Characterization of C3dg Binding to a Recess Formed Between Short Consensus Repeats 1 and 2 of Complement Receptor Type 2 (CR2; CD21)
Wolfgang M. Prodinger, Michael G. Schwendinger, Jürgen Schoch, Maria Köchle, Clara Larcher and Manfred P. Dierich

J Immunol November 1, 1998, 161 (9) 4604-4610;
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IL-7 Reconstitutes Multiple Aspects of v-Abl-Mediated Signaling
Arnob Banerjee and Paul Rothman

J Immunol November 1, 1998, 161 (9) 4611-4617;
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Evidence for a Critical Role for IL-2 in CD40-Mediated Activation of Naive B Cells by Primary CD4 T Cells
Caroline Johnson-Léger, Jillian R. Christenson, Mary Holman and Gerry G. B. Klaus

J Immunol November 1, 1998, 161 (9) 4618-4626;
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The IL-2 Receptor Promotes Proliferation, bcl-2 and bcl-x Induction, But Not Cell Viability Through the Adapter Molecule Shc
James D. Lord, Bryan C. McIntosh, Philip D. Greenberg and Brad H. Nelson

J Immunol November 1, 1998, 161 (9) 4627-4633;
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B Cell Deletion, Anergy, and Receptor Editing in “Knock In” Mice Targeted with a Germline-Encoded or Somatically Mutated Anti-DNA Heavy Chain
Yael Pewzner-Jung, Dinorah Friedmann, Eiichiro Sonoda, Steffen Jung, Klaus Rajewsky and Dan Eilat

J Immunol November 1, 1998, 161 (9) 4634-4645;
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Role of T Cells and Germinal Center Formation in the Generation of Immune Responses to the Thymus-Independent Carbohydrate Dextran B512
Eva Sverremark and Carmen Fernandez

J Immunol November 1, 1998, 161 (9) 4646-4651;
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Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice
Kiyoshi Takeda, Tsuneyasu Kaisho, Nobuaki Yoshida, Junji Takeda, Tadamitsu Kishimoto and Shizuo Akira

J Immunol November 1, 1998, 161 (9) 4652-4660;
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B Cell Responses to a Peptide Epitope. VI. The Kinetics of Antigen Recognition Modulates B Cell-Mediated Recruitment of T Helper Subsets
Lalitha Vijayakrishnan, Venkatasamy Manivel and Kanury V. S. Rao

J Immunol November 1, 1998, 161 (9) 4661-4670;
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CD99 Engagement on Human Peripheral Blood T Cells Results in TCR/CD3-Dependent Cellular Activation and Allows for Th1-Restricted Cytokine Production
Martina Waclavicek, Otto Majdic, Thomas Stulnig, Markus Berger, Raute Sunder-Plassmann, Gerhard J. Zlabinger, Thomas Baumruker, Johannes Stöckl, Christof Ebner, Walter Knapp and Winfried F. Pickl

J Immunol November 1, 1998, 161 (9) 4671-4678;
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Human Endothelial Cells Induce and Regulate Cytolytic T Cell Differentiation
Barbara C. Biedermann and Jordan S. Pober

J Immunol November 1, 1998, 161 (9) 4679-4687;
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Differential Requirements for ZAP-70 in TCR Signaling and T Cell Development
Theresa A. Kadlecek, Nicolai S. C. van Oers, Leo Lefrancois, Sara Olson, Deborah Finlay, David H. Chu, Kari Connolly, Nigel Killeen and Arthur Weiss

J Immunol November 1, 1998, 161 (9) 4688-4694;
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The Fas/Fas Ligand System Is Involved in the Pathogenesis of Autoimmune Myocarditis in Rats
Shigeru Ishiyama, Michiaki Hiroe, Toshio Nishikawa, Takashi Shimojo, Shinji Abe, Hiroyuki Fujisaki, Hiroshi Ito, Katsutoshi Yamakawa, Nobuyuki Kobayashi, Takeshi Kasajima and Fumiaki Marumo

J Immunol November 1, 1998, 161 (9) 4695-4701;
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Ligation of Cell Surface CD38 Protein with Agonistic Monoclonal Antibody Induces a Cell Growth Signal in Myeloid Leukemia Cells
Marina Konopleva, Zeev Estrov, Shourong Zhao, Michael Andreeff and Kapil Mehta

J Immunol November 1, 1998, 161 (9) 4702-4708;
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IL-4 in Combination with TGF-β Favors an Alternative Pathway of Th1 Development Independent of IL-12
Karen Lingnau, Petra Hoehn, Saadia Kerdine, Stephan Koelsch, Christine Neudoerfl, Norbert Palm, Erwin Ruede and Edgar Schmitt

J Immunol November 1, 1998, 161 (9) 4709-4718;

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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A Molecular Basis for How a Single TCR Interfaces Multiple Ligands
Alina Boesteanu, Michael Brehm, Lawrence M. Mylin, Gregory J. Christianson, Satvir S. Tevethia, Derry C. Roopenian and Sebastian Joyce

J Immunol November 1, 1998, 161 (9) 4719-4727;
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The Importance of Pairwise Interactions Between Peptide Residues in the Delineation of TCR Specificity
Graham R. Leggatt, Anne Hosmalin, C. David Pendleton, Anita Kumar, Stephen Hoffman and Jay A. Berzofsky

J Immunol November 1, 1998, 161 (9) 4728-4735;
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p48/STAT-1α-Containing Complexes Play a Predominant Role in Induction of IFN-γ-Inducible Protein, 10 kDa (IP-10) by IFN-γ Alone or in Synergy with TNF-α
Sarmila Majumder, Lucy Z.-H. Zhou, Priya Chaturvedi, Gerald Babcock, Sumer Aras and Richard M. Ransohoff

J Immunol November 1, 1998, 161 (9) 4736-4744;
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Structural Aspects of the Interaction Between Heterogeneic Human Papillomavirus Type 1 E4-Specific T Cell Receptors and the Same Peptide/HLA-DQ8 Complex
Jane C. Steele, Stephen P. Young, Jane C. Goodall and Phillip H. Gallimore

J Immunol November 1, 1998, 161 (9) 4745-4752;
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NF-κB Activation in CD27 Signaling: Involvement of TNF Receptor-Associated Factors in Its Signaling and Identification of Functional Region of CD27
Hiroyasu Yamamoto, Tadamitsu Kishimoto and Seijiro Minamoto

J Immunol November 1, 1998, 161 (9) 4753-4759;
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Regulation of Mouse CD72 Gene Expression During B Lymphocyte Development
Han Ying, James I. Healy, Christopher C. Goodnow and Jane R. Parnes

J Immunol November 1, 1998, 161 (9) 4760-4767;
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FcεRI-Mediated Induction of TNF-α Gene Expression in the RBL-2H3 Mast Cell Line: Regulation by a Novel NF-κB-Like Nuclear Binding Complex
Claire Pelletier, Nadine Varin-Blank, Juan Rivera, Bruno Iannascoli, Françoise Marchand, Bernard David, Anne Weyer and Ulrich Blank

J Immunol November 1, 1998, 161 (9) 4768-4776;
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Invariant Chain Can Bind MHC Class II at a Site Other Than the Peptide Binding Groove
Nancy A. Wilson, Paula Wolf, Hidde Ploegh, Leszek Ignatowicz, John Kappler and Philippa Marrack

J Immunol November 1, 1998, 161 (9) 4777-4784;
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Active Sites in Complement Component C3 Mapped by Mutations at Indels
Ronald T. Ogata, Rong Ai and Pamela J. Low

J Immunol November 1, 1998, 161 (9) 4785-4794;
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Mef2 Proteins, Required for Muscle Differentiation, Bind an Essential Site in the Ig λ Enhancer
Ebenezer Satyaraj and Ursula Storb

J Immunol November 1, 1998, 161 (9) 4795-4802;
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Autocrine/Paracrine IFN-αβ Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1α in Mouse Macrophages: Pivotal Role of Stat1α in Induction of the Inducible Nitric Oxide Synthase Gene
Jian Jun Gao, Michael B. Filla, Marion J. Fultz, Stefanie N. Vogel, Stephen W. Russell and William J. Murphy

J Immunol November 1, 1998, 161 (9) 4803-4810;
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Two Diverged Complement Factor B/C2-Like cDNA Sequences from a Teleost, the Common Carp (Cyprinus carpio)^{1, 2}
Miki Nakao, Yuko Fushitani, Kazuhiro Fujiki, Masaru Nonaka and Tomoki Yano

J Immunol November 1, 1998, 161 (9) 4811-4818;
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The Role of Protein Kinase C Signaling in Activated DRA Transcription
Niclas Setterblad, Isaac Onyango, Ulla Pihlgren, Lars Rask and Göran Andersson

J Immunol November 1, 1998, 161 (9) 4819-4824;
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Mechanism of Catecholamine-Mediated Destabilization of Messenger RNA Encoding Thy-1 Protein in T-Lineage Cells
Sophie A. Wajeman-Chao, Susan A. Lancaster, Lloyd H. Graf Jr. and Donald A. Chambers

J Immunol November 1, 1998, 161 (9) 4825-4833;

HOST DEFENSE

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Mycobacterium avium-intracellulare complex Activates Nuclear Transcription Factor-κB in Different Cell Types Through Reactive Oxygen Intermediates
Dipak K. Giri, Reeta T. Mehta, Rita G. Kansal and Bharat B. Aggarwal

J Immunol November 1, 1998, 161 (9) 4834-4841;
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Defective Function of Langerhans Cells in Tumor-Bearing Animals Is the Result of Defective Maturation from Hemopoietic Progenitors
Tadao Ishida, Tsunehiro Oyama, David P. Carbone and Dmitry I. Gabrilovich

J Immunol November 1, 1998, 161 (9) 4842-4851;
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Rapid and Delayed p42/p44 Mitogen-Activated Protein Kinase Activation by Nitric Oxide: The Role of Cyclic GMP and Tyrosine Phosphatase Inhibition
Dagmar Callsen, Josef Pfeilschifter and Bernhard Brüne

J Immunol November 1, 1998, 161 (9) 4852-4858;
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Astrocyte-Targeted Expression of IFN-α1 Protects Mice from Acute Ocular Herpes Simplex Virus Type 1 Infection
Daniel J. J. Carr, Livia A. Veress, Sansanee Noisakran and Iain L. Campbell

J Immunol November 1, 1998, 161 (9) 4859-4865;
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The IL-1 Receptor-Related T1 Antigen Is Expressed on Immature and Mature Mast Cells and on Fetal Blood Mast Cell Progenitors
Dirk R. Moritz, Hans-Reimer Rodewald, Jacqueline Gheyselinck and Roman Klemenz

J Immunol November 1, 1998, 161 (9) 4866-4874;
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Recognition of Two Overlapping CTL Epitopes in HIV-1 p17 by CTL from a Long-Term Nonprogressing HIV-1-Infected Individual
Thomas Harrer, Ellen Harrer, Peter Barbosa, Friedemann Kaufmann, Ralf Wagner, Susanne Brüggemann, Joachim R. Kalden, Mark Feinberg, R. Paul Johnson, Susan Buchbinder and Bruce D. Walker

J Immunol November 1, 1998, 161 (9) 4875-4881;
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Attenuation of HLA-DR Expression by Mononuclear Phagocytes Infected with Mycobacterium tuberculosis Is Related to Intracellular Sequestration of Immature Class II Heterodimers
Zakaria Hmama, Reinhard Gabathuler, Wilfred A. Jefferies, Gary de Jong and Neil E. Reiner

J Immunol November 1, 1998, 161 (9) 4882-4893;
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Role of the Hypervariable Region in Streptococcal M Proteins: Binding of a Human Complement Inhibitor
Eskil Johnsson, Karin Berggård, Heike Kotarsky, Jens Hellwage, Peter F. Zipfel, Ulf Sjöbring and Gunnar Lindahl

J Immunol November 1, 1998, 161 (9) 4894-4901;
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Gut-Derived Intraepithelial Lymphocytes Induce Long Term Immunity Against Toxoplasma gondii
Anne C. Lepage, Dominique Buzoni-Gatel, Daniel T. Bout and Lloyd H. Kasper

J Immunol November 1, 1998, 161 (9) 4902-4908;
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Proapoptotic Activity of a Trypanosoma cruzi Ceramide-Containing Glycolipid Turned on in Host Macrophages by IFN-γ
Célio G. Freire-de-Lima, Marise P. Nunes, Suzana Corte-Real, Milena P. Soares, José O. Previato, Lúcia Mendonça-Previato and George A. DosReis

J Immunol November 1, 1998, 161 (9) 4909-4916;
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Genetic Immunization Generates Cellular and Humoral Immune Responses Against the Nonstructural Proteins of the Hepatitis C Virus in a Murine Model
Jens Encke, Jasper zu Putlitz, Michael Geissler and Jack R. Wands

J Immunol November 1, 1998, 161 (9) 4917-4923;

INFLAMMATION

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Two Lineages of Mannose-Binding Lectin-Associated Serine Protease (MASP) in Vertebrates
Yuichi Endo, Minoru Takahashi, Miki Nakao, Hidetoshi Saiga, Hideharu Sekine, Misao Matsushita, Masaru Nonaka and Teizo Fujita

J Immunol November 1, 1998, 161 (9) 4924-4930;
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Soluble VCAM-1 Induces Chemotaxis of Jurkat and Synovial Fluid T Cells Bearing High Affinity Very Late Antigen-4
Atsushi Kitani, Noriko Nakashima, Tomomaro Izumihara, Masaki Inagaki, Xu Baoui, Su Yu, Takemasa Matsuda and Takami Matsuyama

J Immunol November 1, 1998, 161 (9) 4931-4938;
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Inhibition by Dexamethasone of Antigen-Induced c-Jun N-Terminal Kinase Activation in Rat Basophilic Leukemia Cells
Noriyasu Hirasawa, Yukako Sato, Yuhko Fujita, Suetsugu Mue and Kazuo Ohuchi

J Immunol November 1, 1998, 161 (9) 4939-4943;
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A His₁₉ to Ala Mutant of Melanoma Growth-Stimulating Activity Is a Partial Antagonist of the CXCR2 Receptor
Deborah L. Baly, Richard Horuk, Daniel G. Yansura, Laura C. Simmons, Wayne J. Fairbrother, Claire Kotts, Cindy M. Wirth, Beth L. Gillece-Castro, Karen Toy, Joseph Hesselgesser and David E. Allison

J Immunol November 1, 1998, 161 (9) 4944-4949;
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Activation of the RON Receptor Tyrosine Kinase Inhibits Inducible Nitric Oxide Synthase (iNOS) Expression by Murine Peritoneal Exudate Macrophages: Phosphatidylinositol-3 Kinase Is Required for RON-Mediated Inhibition of iNOS Expression
Yi-Qing Chen, James H. Fisher and Ming-Hai Wang

J Immunol November 1, 1998, 161 (9) 4950-4959;
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Dexamethasone But Not Indomethacin Inhibits Human Phagocyte Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity by Down-Regulating Expression of Genes Encoding Oxidase Components
Antonio Condino-Neto, Constance Whitney and Peter E. Newburger

J Immunol November 1, 1998, 161 (9) 4960-4967;
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Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Assembly and Activation in EBV-Transformed B Lymphoblastoid Cell Lines of Normal and Chronic Granulomatous Disease Patients
Stefano Dusi, Katyuscia A. Nadalini, Marta Donini, Lorena Zentilin, Frans B. Wientjes, Dirk Roos, Mauro Giacca and Filippo Rossi

J Immunol November 1, 1998, 161 (9) 4968-4974;
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Novel C-Terminally Truncated Isoforms of the CXC Chemokine β-Thromboglobulin and Their Impact on Neutrophil Functions
Jan Erik Ehlert, Johannes Gerdes, Hans-Dieter Flad and Ernst Brandt

J Immunol November 1, 1998, 161 (9) 4975-4982;
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Fusion of Azurophil Granules with Phagosomes and Activation of the Tyrosine Kinase Hck Are Specifically Inhibited During Phagocytosis of Mycobacteria by Human Neutrophils
Elsa-Noah N’Diaye, Xavier Darzacq, Catherine Astarie-Dequeker, Mamadou Daffé, Jero Calafat and Isabelle Maridonneau-Parini

J Immunol November 1, 1998, 161 (9) 4983-4991;
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Role of IL-6 and the Soluble IL-6 Receptor in Inhibition of VCAM-1 Gene Expression
Jae-Wook Oh, Nicholas J. Van Wagoner, Stefan Rose-John and Etty N. Benveniste

J Immunol November 1, 1998, 161 (9) 4992-4999;
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Oncostatin M Up-Regulates Tissue Inhibitor of Metalloproteinases-3 Gene Expression in Articular Chondrocytes via De Novo Transcription, Protein Synthesis, and Tyrosine Kinase- and Mitogen-Activated Protein Kinase-Dependent Mechanisms
Wen Qing Liand and Muhammad Zafarullah

J Immunol November 1, 1998, 161 (9) 5000-5007;
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Induction of Cyclooxygenase-2 by Secretory Phospholipases A₂ in Nerve Growth Factor-Stimulated Rat Serosal Mast Cells Is Facilitated by Interaction with Fibroblasts and Mediated by a Mechanism Independent of Their Enzymatic Functions
Kinji Tada, Makoto Murakami, Terumi Kambe and Ichiro Kudo

J Immunol November 1, 1998, 161 (9) 5008-5015;
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Transgenic Expression of IFN-α in the Central Nervous System of Mice Protects Against Lethal Neurotropic Viral Infection but Induces Inflammation and Neurodegeneration
Yvette Akwa, Daniel E. Hassett, Maija-Leena Eloranta, Kristian Sandberg, Eliezer Masliah, Henry Powell, J. Lindsay Whitton, Floyd E. Bloom and Iain L. Campbell

J Immunol November 1, 1998, 161 (9) 5016-5026;
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STCP-1 (MDC) CC Chemokine Acts Specifically on Chronically Activated Th2 Lymphocytes and Is Produced by Monocytes on Stimulation with Th2 Cytokines IL-4 and IL-13
David P. Andrew, Ming-shi Chang, Jennifer McNinch, Scott T. Wathen, Marynette Rihanek, Julia Tseng, Jason P. Spellberg and Chester G. Elias III

J Immunol November 1, 1998, 161 (9) 5027-5038;
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Thrombin Receptor Activation Inhibits Monocyte Spreading by Induction of ET_B Receptor-Coupled Nitric Oxide Release
Kamal D. Srivastava and Harold I. Magazine

J Immunol November 1, 1998, 161 (9) 5039-5044;

CLINICAL IMMUNOLOGY

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HLA-DQ6/8 Double Transgenic Mice Develop Auricular Chondritis Following Type II Collagen Immunization: A Model for Human Relapsing Polychondritis
David S. Bradley, Pritam Das, Marie M. Griffiths, Harvinder S. Luthra and Chella S. David

J Immunol November 1, 1998, 161 (9) 5046-5053;
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Prevention of Th2-Like Cell Responses by Coadministration of IL-12 and IL-18 Is Associated with Inhibition of Antigen-Induced Airway Hyperresponsiveness, Eosinophilia, and Serum IgE Levels
Claudia L. Hofstra, Ingrid Van Ark, Gerard Hofman, Mirjam Kool, Frans P. Nijkamp and Antoon J. M. Van Oosterhout

J Immunol November 1, 1998, 161 (9) 5054-5060;
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Accessibility of SSA/Ro and SSB/La Antigens to Maternal Autoantibodies in Apoptotic Human Fetal Cardiac Myocytes
M. Eugenia Miranda, Chung-E Tseng, William Rashbaum, Robert L. Ochs, Carlos A. Casiano, Francis Di Donato, Edward K. L. Chan and Jill P. Buyon

J Immunol November 1, 1998, 161 (9) 5061-5069;
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Antibody Repertoire Development in Fetal and Neonatal Piglets. I. Four V_H Genes Account for 80 Percent of V_H Usage During 84 Days of Fetal Life
J. Sun, C. Hayward, R. Shinde, R. Christenson, S. P. Ford and J. E. Butler

J Immunol November 1, 1998, 161 (9) 5070-5078;
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Identification of Basophilic Cells that Express Mast Cell Granule Proteases in the Peripheral Blood of Asthma, Allergy, and Drug-Reactive Patients
Lixin Li, Yong Li, Stephen W. Reddel, Maya Cherrian, Daniel S. Friend, Richard L. Stevens and Steven A. Krilis

J Immunol November 1, 1998, 161 (9) 5079-5086;
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In Vivo Treatment with a MHC Class I-Restricted Blocking Peptide Can Prevent Virus-Induced Autoimmune Diabetes
Matthias G. von Herrath, Bryan Coon, Hanna Lewicki, Honore Mazarguil, Jean Edouard Gairin and Michael B. A. Oldstone

J Immunol November 1, 1998, 161 (9) 5087-5096;
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Antibodies Against IL-12 Prevent Superantigen-Induced and Spontaneous Relapses of Experimental Autoimmune Encephalomyelitis
Cris S. Constantinescu, Maria Wysocka, Brendan Hilliard, Elvira S. Ventura, Ehud Lavi, Giorgio Trinchieri and Abdolmohamad Rostami

J Immunol November 1, 1998, 161 (9) 5097-5104;

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Table of Contents

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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