Cutting Edge: IL-4-Independent Induction of Airway Hyperresponsiveness by Th2, But Not Th1, Cells

Lauren Cohn; Jeffrey S. Tepper; Kim Bottomly

Article Information

vol. 161 no. 8 3813-3816

PubMed

9780144

Published By

The American Association of Immunologists, Inc.

Print ISSN

0022-1767

Online ISSN

1550-6606

History

Received June 24, 1998
Accepted August 12, 1998
Published online October 15, 1998.

Author Information

Lauren Cohn²,^*,^†,
Jeffrey S. Tepper^‡ and
Kim Bottomly^*,^§

Sections of
^*Immunobiology and
^†Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, CT 06520;
^‡Immunology Research, Genentech, Inc., South San Francisco, CA 94080; and
^§Howard Hughes Medical Institute, New Haven, CT 06536

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Article usage: September 2000 to July 2022

	Abstract	Full	Pdf
Sep 2000	0	6	3
Oct 2000	2	10	12
Nov 2000	10	16	8
Dec 2000	2	9	5
Total 2000	14	41	28
Jan 2001	3	10	11
Feb 2001	5	13	10
Mar 2001	5	17	15
Apr 2001	2	5	6
May 2001	9	15	13
Jun 2001	4	17	15
Jul 2001	4	12	17
Aug 2001	3	14	15
Sep 2001	2	13	15
Oct 2001	3	12	10
Nov 2001	2	14	13
Dec 2001	2	10	8
Total 2001	44	152	148
Jan 2002	4	24	19
Feb 2002	2	7	11
Mar 2002	10	14	18
Apr 2002	9	20	13
May 2002	5	12	20
Jun 2002	3	8	9
Jul 2002	3	14	8
Aug 2002	1	10	16
Sep 2002	3	15	14
Oct 2002	4	10	12
Nov 2002	5	5	8
Dec 2002	7	15	17
Total 2002	56	154	165
Jan 2003	8	11	16
Feb 2003	1	9	10
Mar 2003	3	5	10
Apr 2003	2	11	10
May 2003	2	15	11
Jun 2003	5	19	11
Jul 2003	4	15	10
Aug 2003	5	11	6
Sep 2003	11	25	11
Oct 2003	14	21	16
Nov 2003	10	27	8
Dec 2003	13	15	6
Total 2003	78	184	125
Jan 2004	14	23	12
Feb 2004	4	22	8
Mar 2004	6	22	9
Apr 2004	12	30	19
May 2004	10	21	13
Jun 2004	14	19	10
Jul 2004	10	38	15
Aug 2004	20	21	10
Sep 2004	14	32	5
Oct 2004	12	30	3
Nov 2004	6	29	10
Dec 2004	11	28	10
Total 2004	133	315	124
Jan 2005	2	35	8
Feb 2005	8	22	12
Mar 2005	20	20	7
Apr 2005	8	17	12
May 2005	8	12	15
Jun 2005	6	27	11
Jul 2005	8	13	6
Aug 2005	4	10	5
Sep 2005	3	12	4
Oct 2005	9	11	8
Nov 2005	13	16	6
Dec 2005	7	7	3
Total 2005	96	202	97
Jan 2006	2	18	6
Feb 2006	9	16	9
Mar 2006	3	14	4
Apr 2006	5	14	8
May 2006	7	6	6
Jun 2006	5	12	10
Jul 2006	2	7	6
Aug 2006	14	5	10
Sep 2006	3	15	8
Oct 2006	5	11	3
Nov 2006	10	23	9
Dec 2006	10	19	3
Total 2006	75	160	82
Jan 2007	5	18	11
Feb 2007	3	11	5
Mar 2007	5	16	8
Apr 2007	10	19	6
May 2007	6	15	9
Jun 2007	0	8	6
Jul 2007	3	7	6
Aug 2007	7	25	13
Sep 2007	1	11	7
Oct 2007	3	13	7
Nov 2007	1	8	6
Dec 2007	3	15	9
Total 2007	47	166	93
Jan 2008	3	9	7
Feb 2008	6	6	6
Mar 2008	7	16	16
Apr 2008	10	12	9
May 2008	6	5	3
Jun 2008	7	13	3
Jul 2008	6	8	3
Aug 2008	10	11	11
Sep 2008	3	5	5
Oct 2008	4	4	7
Nov 2008	7	7	9
Dec 2008	5	5	25
Total 2008	74	101	104
Jan 2009	5	8	21
Feb 2009	5	8	10
Mar 2009	2	2	1
Apr 2009	5	12	10
May 2009	10	8	8
Jun 2009	6	15	9
Jul 2009	7	10	5
Aug 2009	5	8	11
Sep 2009	5	7	8
Oct 2009	5	3	6
Nov 2009	6	4	11
Dec 2009	4	10	17
Total 2009	65	95	117
Jan 2010	4	8	10
Feb 2010	5	6	8
Mar 2010	9	12	8
Apr 2010	4	9	9
May 2010	5	10	4
Jun 2010	5	6	8
Jul 2010	2	3	4
Aug 2010	9	10	12
Sep 2010	6	6	10
Oct 2010	2	5	5
Nov 2010	5	10	6
Dec 2010	6	12	1
Total 2010	62	97	85
Jan 2011	3	5	9
Feb 2011	3	5	4
Mar 2011	8	9	21
Apr 2011	8	14	8
May 2011	7	10	10
Jun 2011	12	8	13
Jul 2011	7	5	8
Aug 2011	5	2	8
Sep 2011	14	9	5
Oct 2011	7	7	6
Nov 2011	8	4	4
Dec 2011	13	3	15
Total 2011	95	81	111
Jan 2012	4	9	5
Feb 2012	10	10	11
Mar 2012	13	2	7
Apr 2012	5	2	5
May 2012	10	7	6
Jun 2012	15	4	5
Jul 2012	17	7	6
Aug 2012	12	7	6
Sep 2012	9	4	3
Oct 2012	7	10	7
Nov 2012	3	4	3
Dec 2012	5	4	3
Total 2012	110	70	67
Jan 2013	3	8	9
Feb 2013	1	2	2
Mar 2013	12	10	12
Apr 2013	6	6	6
May 2013	8	5	8
Jun 2013	6	2	4
Jul 2013	4	1	1
Aug 2013	4	9	4
Sep 2013	7	2	2
Oct 2013	12	14	6
Nov 2013	5	0	1
Dec 2013	4	2	3
Total 2013	72	61	58
Jan 2014	2	7	1
Feb 2014	6	3	2
Mar 2014	4	4	4
Apr 2014	8	7	10
May 2014	7	2	1
Jun 2014	8	0	2
Jul 2014	8	5	3
Aug 2014	8	7	8
Sep 2014	4	1	3
Oct 2014	4	8	8
Nov 2014	1	2	2
Dec 2014	0	3	4
Total 2014	60	49	48
Jan 2015	4	2	4
Feb 2015	8	6	7
Mar 2015	5	4	2
Apr 2015	4	1	3
May 2015	9	5	7
Jun 2015	1	8	5
Jul 2015	1	10	4
Aug 2015	8	8	11
Sep 2015	8	4	4
Oct 2015	6	2	1
Nov 2015	6	1	2
Dec 2015	3	2	4
Total 2015	63	53	54
Jan 2016	3	1	4
Feb 2016	6	1	4
Mar 2016	3	5	15
Apr 2016	3	5	3
May 2016	4	0	1
Jun 2016	6	4	3
Jul 2016	7	7	5
Aug 2016	8	1	5
Sep 2016	7	3	4
Oct 2016	5	4	3
Nov 2016	5	3	5
Dec 2016	10	3	5
Total 2016	67	37	57
Jan 2017	0	4	5
Feb 2017	1	8	4
Mar 2017	2	6	6
Apr 2017	1	9	3
May 2017	1	9	11
Jun 2017	4	8	5
Jul 2017	4	7	4
Aug 2017	2	11	0
Sep 2017	0	17	5
Oct 2017	1	15	0
Nov 2017	1	13	2
Dec 2017	3	24	3
Total 2017	20	131	48
Jan 2018	4	17	3
Feb 2018	15	11	5
Mar 2018	25	10	4
Apr 2018	35	14	4
May 2018	1	12	6
Jun 2018	2	15	5
Jul 2018	0	14	4
Aug 2018	0	9	1
Sep 2018	1	11	3
Oct 2018	0	17	5
Nov 2018	1	13	1
Dec 2018	2	16	5
Total 2018	86	159	46
Jan 2019	1	12	1
Feb 2019	0	8	3
Mar 2019	1	2	3
Apr 2019	4	6	4
May 2019	0	4	3
Jun 2019	1	6	3
Jul 2019	1	8	2
Aug 2019	2	14	3
Sep 2019	0	60	6
Oct 2019	5	103	1
Nov 2019	2	72	2
Dec 2019	1	15	9
Total 2019	18	310	40
Jan 2020	1	29	2
Feb 2020	1	14	3
Mar 2020	4	13	4
Apr 2020	1	17	4
May 2020	1	9	1
Jun 2020	1	6	0
Jul 2020	1	5	0
Aug 2020	2	6	0
Sep 2020	3	33	0
Oct 2020	14	35	5
Nov 2020	3	5	2
Dec 2020	3	27	5
Total 2020	35	199	26
Jan 2021	3	4	7
Feb 2021	1	5	6
Mar 2021	1	8	4
Apr 2021	2	8	3
May 2021	0	7	0
Jun 2021	2	6	3
Jul 2021	2	1	5
Aug 2021	0	3	1
Sep 2021	2	0	1
Oct 2021	0	7	8
Nov 2021	6	3	4
Dec 2021	4	4	6
Total 2021	23	56	48
Jan 2022	0	2	2
Feb 2022	3	7	1
Mar 2022	0	2	3
Apr 2022	0	1	0
May 2022	1	7	1
Jun 2022	2	1	2
Jul 2022	0	2	1
Total 2022	6	22	10
Total	1399	2895	1781