The Journal of Immunology: 161 (8)

October 15, 1998; Volume 161,Issue 8

CUTTING EDGE

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Cutting Edge: Presence of Progenitors Restricted to T, B, or Myeloid Lineage, but Absence of Multipotent Stem Cells, in the Murine Fetal Thymus
Hiroshi Kawamoto, Koichiro Ohmura and Yoshimoto Katsura

J Immunol October 15, 1998, 161 (8) 3799-3802;
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Cutting Edge: Negative Regulation of Human T Cell Activation by the Receptor-Type Protein Tyrosine Phosphatase CD148
Stuart G. Tangye, Jun Wu, Gregorio Aversa, Jan E. de Vries, Lewis L. Lanier and Joseph H. Phillips

J Immunol October 15, 1998, 161 (8) 3803-3807;
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Cutting Edge: Cross-Priming of CTL Responses In Vivo Does Not Require Antigenic Peptides in the Endoplasmic Reticulum of Immunizing Cells
Stephen P. Schoenberger, Ellen I. H. van der Voort, G. Menno Krietemeijer, Rienk Offringa, Cornelis J. M. Melief and Rene E. M. Toes

J Immunol October 15, 1998, 161 (8) 3808-3812;
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Cutting Edge: IL-4-Independent Induction of Airway Hyperresponsiveness by Th2, But Not Th1, Cells
Lauren Cohn, Jeffrey S. Tepper and Kim Bottomly

J Immunol October 15, 1998, 161 (8) 3813-3816;
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Cutting Edge: Differential Responsiveness of the IL-5 and IL-4 Genes to Transcription Factor GATA-3
Dong-Hong Zhang, Liyan Yang and Anuradha Ray

J Immunol October 15, 1998, 161 (8) 3817-3821;
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Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation
Sheila Ranganath, Wenjun Ouyang, Deepta Bhattarcharya, William C. Sha, Andrew Grupe, Gary Peltz and Kenneth M. Murphy

J Immunol October 15, 1998, 161 (8) 3822-3826;

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Qualitative and Quantitative Effects of CD28/B7-Mediated Costimulation on Naive T Cells In Vitro
Shivanthi P. Manickasingham, Stephen M. Anderton, Christoph Burkhart and David C. Wraith

J Immunol October 15, 1998, 161 (8) 3827-3835;
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Transfer of Primitive Stem/Progenitor Bone Marrow Cells from LTα^−/− Donors to Wild-Type Hosts: Implications for the Generation of Architectural Events in Lymphoid B Cell Domains
Reina E. Mebius, Silvy van Tuijl, Irving L. Weissman and Troy D. Randall

J Immunol October 15, 1998, 161 (8) 3836-3843;
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High Antigen Density and IL-2 Are Required for Generation of CD4 Effectors Secreting Th1 Rather Than Th0 Cytokines
Paul R. Rogers, Gail Huston and Susan L. Swain

J Immunol October 15, 1998, 161 (8) 3844-3852;
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c-Fos Induces Apoptosis in Germinal Center B Cells
Kunimasa Inada, Seiji Okada, Janyaporn Phuchareon, Masahiko Hatano, Toyohiko Sugimoto, Hideshige Moriya and Takeshi Tokuhisa

J Immunol October 15, 1998, 161 (8) 3853-3861;
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Therapy with Monoclonal Antibodies. II. The Contribution of Fcγ Receptor Binding and the Influence of C_H1 and C_H3 Domains on In Vivo Effector Function
John D. Isaacs, Judith Greenwood and Herman Waldmann

J Immunol October 15, 1998, 161 (8) 3862-3869;
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Long-Lasting Protective Immunity to Experimental Autoimmune Encephalomyelitis Following Vaccination with Naked DNA Encoding C-C Chemokines
Sawsan Youssef, Gizi Wildbaum, Gila Maor, Noami Lanir, Alumit Gour-Lavie, Nir Grabie and Nathan Karin

J Immunol October 15, 1998, 161 (8) 3870-3879;
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SLP-76 Expression Is Restricted to Hemopoietic Cells of Monocyte, Granulocyte, and T Lymphocyte Lineage and Is Regulated During T Cell Maturation and Activation
James L. Clements, Susan E. Ross-Barta, Lorraine T. Tygrett, Thomas J. Waldschmidt and Gary A. Koretzky

J Immunol October 15, 1998, 161 (8) 3880-3889;
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Effects of Bacterial DNA on Cytokine Production by (NZB/NZW)F₁ Mice
Gary S. Gilkeson, Jacqueline Conover, Melissa Halpern, David S. Pisetsky, Amy Feagin and Dennis M. Klinman

J Immunol October 15, 1998, 161 (8) 3890-3895;
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Development of Peptide-Selected CD8 T Cells in Fetal Thymic Organ Culture Occurs via the Conventional Pathway
Kristin A. Hogquist and Jody L. Bonnevier

J Immunol October 15, 1998, 161 (8) 3896-3901;
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Adhesive and/or Signaling Functions of CD44 Isoforms in Human Dendritic Cells
Hélène Haegel-Kronenberger, Henri de la Salle, Alain Bohbot, Francis Oberling, Jean-Pierre Cazenave and Daniel Hanau

J Immunol October 15, 1998, 161 (8) 3902-3911;
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B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice
David V. Serreze, Sara A. Fleming, Harold D. Chapman, Scott D. Richard, Edward H. Leiter and Roland M. Tisch

J Immunol October 15, 1998, 161 (8) 3912-3918;
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Positive and Negative Regulation of Human T Cell Activation Mediated by the CTLA-4/CD28 Ligand CD80
George Boulougouris, Julie D. McLeod, Yusuf I. Patel, Claire N. Ellwood, Lucy S. K. Walker and David M. Sansom

J Immunol October 15, 1998, 161 (8) 3919-3924;
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Functional Analysis of Peripheral Blood B Cells in Patients with X-Linked Agammaglobulinemia
Shigeaki Nonoyama, Satoshi Tsukada, Tomoki Yamadori, Toshio Miyawaki, Yin Zhu Jin, Chiaki Watanabe, Tomohiro Morio, Jun-Ichi Yata and Hans D. Ochs

J Immunol October 15, 1998, 161 (8) 3925-3929;
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Cyclosporin A Enhances IL-12 Production by CpG Motifs in Bacterial DNA and Synthetic Oligodeoxynucleotides
Thomas W. Redford, Ae-Kyung Yi, Courtney T. Ward and Arthur M. Krieg

J Immunol October 15, 1998, 161 (8) 3930-3935;
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FLIP Prevents Apoptosis Induced by Death Receptors But Not by Perforin/Granzyme B, Chemotherapeutic Drugs, and Gamma Irradiation
Takao Kataoka, Michael Schröter, Michael Hahne, Pascal Schneider, Martin Irmler, Margot Thome, Cristopher J. Froelich and Jürg Tschopp

J Immunol October 15, 1998, 161 (8) 3936-3942;
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The Regulation of CD95 Ligand Expression and Function in CTL
Jie-hui Li, Dalia Rosen, Denise Ronen, Christian K. Behrens, Peter H. Krammer, William R. Clark and Gideon Berke

J Immunol October 15, 1998, 161 (8) 3943-3949;
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TGF-β1 Somatic Gene Therapy Prevents Autoimmune Disease in Nonobese Diabetic Mice
Ciriaco A. Piccirillo, Yigang Chang and Gérald J. Prud’homme

J Immunol October 15, 1998, 161 (8) 3950-3956;
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Molecular Mechanisms of Immune-Mediated Lysis of Murine Renal Cancer: Differential Contributions of Perforin-Dependent Versus Fas-Mediated Pathways in Lysis by NK and T Cells
Thomas J. Sayers, Alan D. Brooks, Jong-Keuk Lee, Robert G. Fenton, Kristin L. Komschlies, Jon M. Wigginton, Robin Winkler-Pickett and Robert H. Wiltrout

J Immunol October 15, 1998, 161 (8) 3957-3965;
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Initiation of the Autologous Mixed Lymphocyte Reaction Requires the Expression of Costimulatory Molecules B7-1 and B7-2 on Human Peripheral Blood Dendritic Cells
Clemens Scheinecker, Klaus P. Machold, Otto Majdic, Paul Höcker, Walter Knapp and Josef S. Smolen

J Immunol October 15, 1998, 161 (8) 3966-3973;
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Deletion of Bone Marrow Stromal Cell Antigen-1 (CD157) Gene Impaired Systemic Thymus Independent-2 Antigen-Induced IgG3 and Mucosal TD Antigen-Elicited IgA Responses
Motoyuki Itoh, Katsuhiko Ishihara, Takachika Hiroi, Byung Ok Lee, Hisoka Maeda, Hideki Iijima, Manabu Yanagita, Hiroshi Kiyono and Toshio Hirano

J Immunol October 15, 1998, 161 (8) 3974-3983;
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Critical Involvement of Tcf-1 in Expansion of Thymocytes
Marco W. Schilham, Anne Wilson, Petra Moerer, Barry J. Benaissa-Trouw, Ana Cumano and Hans C. Clevers

J Immunol October 15, 1998, 161 (8) 3984-3991;
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Normal Thymic Selection of TCR Transgenic CD4 T Cells, but Impaired Survival in the Periphery Despite the Presence of Selecting MHC Molecules
Thomas Barthlott, Rebecca J. Wright and Brigitta Stockinger

J Immunol October 15, 1998, 161 (8) 3992-3999;
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Lipid Vesicle Size Determines the Th1 or Th2 Response to Entrapped Antigen
James M. Brewer, Laurence Tetley, James Richmond, Foo Y. Liew and James Alexander

J Immunol October 15, 1998, 161 (8) 4000-4007;
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Localization of Splenic B Cells Activated for Switch Recombination by In Situ Hybridization with Iγ1 Switch Transcript and Rad51 Probes
Marie-Claire Peakman and Nancy Maizels

J Immunol October 15, 1998, 161 (8) 4008-4015;
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Affinity and Kinetic Analysis of the Molecular Interaction of ICAM-1 and Leukocyte Function-Associated Antigen-1
Yuichi Tominaga, Yasuo Kita, Atsushi Satoh, Satoshi Asai, Kimitoshi Kato, Koichi Ishikawa, Tadashi Horiuchi and Tohru Takashi

J Immunol October 15, 1998, 161 (8) 4016-4022;
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Rapid Extracellular Degradation of Synthetic Class I Peptides by Human Dendritic Cells
Andrew A. Amoscato, Damon A. Prenovitz and Michael T. Lotze

J Immunol October 15, 1998, 161 (8) 4023-4032;
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Murine Langerhans Cells Cultured Under Serum-Free Conditions Mature into Potent Stimulators of Primary Immune Responses In Vitro and In Vivo
Alena Kočiková, Andrea Kolesarić, Frieder Koszik, Georg Stingl and Adelheid Elbe-Bürger

J Immunol October 15, 1998, 161 (8) 4033-4041;
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Inhibitory and Stimulatory Functions of Paired Ig-Like Receptor (PIR) Family in RBL-2H3 Cells
Yumi Yamashita, Masao Ono and Toshiyuki Takai

J Immunol October 15, 1998, 161 (8) 4042-4047;
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Large Protein Fragments as Substrates for Endocytic Antigen Capture by MHC Class II Molecules
Flora Castellino, Francesca Zappacosta, John E. Coligan and Ronald N. Germain

J Immunol October 15, 1998, 161 (8) 4048-4057;
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CD3/TCR Complex-Associated Lymphocyte Activation Gene-3 Molecules Inhibit CD3/TCR Signaling
Sigrid Hannier, Muriel Tournier, Georges Bismuth and Frédéric Triebel

J Immunol October 15, 1998, 161 (8) 4058-4065;

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Genomics, Isoforms, Expression, and Phylogeny of the MHC Class I-Related MR1 Gene
Patricia Riegert, Valérie Wanner and Seiamak Bahram

J Immunol October 15, 1998, 161 (8) 4066-4077;
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Definition of Natural T Cell Antigens with Mimicry Epitopes Obtained from Dedicated Synthetic Peptide Libraries
Hoebert S. Hiemstra, Peter A. van Veelen, Nanette C. Schloot, Annemieke Geluk, Krista E. van Meijgaarden, Sabine J. M. Willemen, Jack A. M. Leunissen, Willemien E. Benckhuijsen, Reinout Amons, René R. P. de Vries, Bart O. Roep, Tom H. M. Ottenhoff and Jan W. Drijfhout

J Immunol October 15, 1998, 161 (8) 4078-4082;
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Comparisons of the Ability of Human IgG3 Hinge Mutants, IgM, IgE, and IgA2, to Form Small Immune Complexes: A Role for Flexibility and Geometry
Kenneth H. Roux, Lioudmila Strelets, Ole Henrik Brekke, Inger Sandlie and Terje E. Michaelsen

J Immunol October 15, 1998, 161 (8) 4083-4090;
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Production of IgM Hexamers by Normal and Autoimmune B Cells: Implications for the Physiologic Role of Hexameric IgM
C. Todd Hughey, Joseph W. Brewer, Ann D. Colosia, Wendell F. Rosse and Ronald B. Corley

J Immunol October 15, 1998, 161 (8) 4091-4097;
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The Role of Ets-1 in Mast Cell Granulocyte-Macrophage Colony-Stimulating Factor Expression and Activation
Leigh H. McKinlay, Martin J. Tymms, Ross S. Thomas, Arun Seth, Suzanne Hasthorpe, Paul J. Hertzog and Ismail Kola

J Immunol October 15, 1998, 161 (8) 4098-4105;
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Cloning, Structure, and Function of Two Rainbow Trout Bf Molecules
J. Oriol Sunyer, Ioannis Zarkadis, Maria Rosa Sarrias, John D. Hansen and John D. Lambris

J Immunol October 15, 1998, 161 (8) 4106-4114;

HOST DEFENSE

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A Nontoxic Adjuvant for Mucosal Immunity to Pneumococcal Surface Protein A
Masafumi Yamamoto, David E. Briles, Shingo Yamamoto, Mari Ohmura, Hiroshi Kiyono and Jerry R. McGhee

J Immunol October 15, 1998, 161 (8) 4115-4121;
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Nitric Oxide Prevents IL-1β and IFN-γ-Inducing Factor (IL-18) Release from Macrophages by Inhibiting Caspase-1 (IL-1β-Converting Enzyme)
Young-Myeong Kim, Robert V. Talanian, Jianrong Li and Timothy R. Billiar

J Immunol October 15, 1998, 161 (8) 4122-4128;
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The Schistosome Granuloma: Characterization of Lymphocyte Migration, Activation, and Cytokine Production
Catherine A. Rumbley, S. Ali Zekavat, Hiroko Sugaya, Peter J. Perrin, Mohamad Ali Ramadan and S. Michael Phillips

J Immunol October 15, 1998, 161 (8) 4129-4137;
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Down-Regulation of Tumoricidal NK and NK T Cell Activities by MHC K^b Molecules Expressed on Th2-Type γδ T and αβ T Cells Coinfiltrating in Early B16 Melanoma Lesions
Naohiro Seo, Yoshiki Tokura, Fukumi Furukawa and Masahiro Takigawa

J Immunol October 15, 1998, 161 (8) 4138-4145;
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Heat-Killed Listeria monocytogenes as an Adjuvant Converts Established Murine Th2-Dominated Immune Responses into Th1-Dominated Responses
V. Peter Yeung, Randall S. Gieni, Dale T. Umetsu and Rosemarie H. DeKruyff

J Immunol October 15, 1998, 161 (8) 4146-4152;
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Blockade of CTLA-4 Enhances Host Resistance to the Intracellular Pathogen, Leishmania donovani
Michaela L. Murphy, Sara E. J. Cotterell, Patricia M. A. Gorak, Christian R. Engwerda and Paul M. Kaye

J Immunol October 15, 1998, 161 (8) 4153-4160;
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Dermal Endothelial Cells and Keratinocytes Produce IL-7 In Vivo After Human Schistosoma mansoni Percutaneous Infection
Olivier Roye, Nadirah Delhem, François Trottein, Franck Remoué, Sophie Nutten, Jean-Pierre Decavel, Myriam Delacre, Véronique Martinot, Jean-Yves Cesbron, Claude Auriault and Isabelle Wolowczuk

J Immunol October 15, 1998, 161 (8) 4161-4168;
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Peripheral Blood-Derived CD34⁺ Progenitor Cells: CXC Chemokine Receptor 4 and CC Chemokine Receptor 5 Expression and Infection by HIV
Margaret E. Ruiz, Claudia Cicala, James Arthos, Audrey Kinter, Andrew T. Catanzaro, Joseph Adelsberger, Kevin L. Holmes, Oren J. Cohen and Anthony S. Fauci

J Immunol October 15, 1998, 161 (8) 4169-4176;
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Haemophilus influenzae Type b Polysaccharides-Protein Conjugate Vaccine Elicits a More Diverse Antibody Repertoire in Infants Than in Adults
Elisabeth E. Adderson, Patricia M. Wilson, Madeleine W. Cunningham and Penelope G. Shackelford

J Immunol October 15, 1998, 161 (8) 4177-4182;
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Functional Dissociation Between Local and Systemic Immune Response During Anti-Melanoma Peptide Vaccination
Kang-Hun Lee, Monica C. Panelli, Christina J. Kim, Adam I. Riker, Maria P. Bettinotti, Matthew M. Roden, Patricia Fetsch, Andrea Abati, Steven A. Rosenberg and Francesco M. Marincola

J Immunol October 15, 1998, 161 (8) 4183-4194;
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Weak Anamnestic Responses of Inbred Mice to Yersinia F1 Genetic Vaccine Are Overcome by Boosting with F1 Polypeptide While Outbred Mice Remain Nonresponsive
Patricia Brandler, Kamal U. Saikh, David Heath, Arthur Friedlander and Robert G. Ulrich

J Immunol October 15, 1998, 161 (8) 4195-4200;
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IFN-γ, IL-12, and TNF-α Are Required to Maintain Reduced Liver Pathology in Mice Vaccinated with Schistosoma mansoni Eggs and IL-12
Karl F. Hoffmann, Pat Caspar, Allen W. Cheever and Thomas A. Wynn

J Immunol October 15, 1998, 161 (8) 4201-4210;
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Comparison of Humoral Immune Responses Elicited by DNA and Protein Vaccines Based on Merozoite Surface Protein-1 from Plasmodium yoelii, a Rodent Malaria Parasite
Yang Kang, Paul A. Calvo, Thomas M. Daly and Carole A. Long

J Immunol October 15, 1998, 161 (8) 4211-4219;
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Apoptosis of Epithelial Cells and Macrophages Due to Infection with the Obligate Intracellular Pathogen Chlamydia psittaci
David M. Ojcius, Philippe Souque, Jean-Luc Perfettini and Alice Dautry-Varsat

J Immunol October 15, 1998, 161 (8) 4220-4226;
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The Memory B Cell Subset Responsible for the Secretory IgA Response and Protective Humoral Immunity to Rotavirus Expresses the Intestinal Homing Receptor, α₄β₇
Marna B. Williams, Jason R. Rosé, Lusijah S. Rott, Manuel A. Franco, Harry B. Greenberg and Eugene C. Butcher

J Immunol October 15, 1998, 161 (8) 4227-4235;

INFLAMMATION

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CC-3052: A Water-Soluble Analog of Thalidomide and Potent Inhibitor of Activation-Induced TNF-α Production
J. Blake Marriott, Michael Westby, Sharon Cookson, Mary Guckian, Steve Goodbourn, George Muller, Mary G. Shire, David Stirling and Angus G. Dalgleish

J Immunol October 15, 1998, 161 (8) 4236-4243;
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Soluble CD14_1–152 Confers Responsiveness to Both Lipoarabinomannan and Lipopolysaccharide in a Novel HL-60 Cell Bioassay
Weiming Yu, Elisa Soprana, Giovanna Cosentino, Manuela Volta, Henri S. Lichenstein, Giovanna Viale and Donata Vercelli

J Immunol October 15, 1998, 161 (8) 4244-4251;
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Thymic Expression of the Transcription Factor Nur77 Rescues the T Cell But Not the B Cell Abnormality of gld/gld Mice
Francis Ka-Ming Chan and Ann Chen Astar Winoto

J Immunol October 15, 1998, 161 (8) 4252-4256;
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Chronically HIV-1-Infected Monocytic Cells Induce Apoptosis in Cocultured T Cells
Houchu Chen, Y. K. Yip, Italas George, Max Tyorkin, Erez Salik and Kirk Sperber

J Immunol October 15, 1998, 161 (8) 4257-4267;
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Oleic Acid Increases Cell Surface Expression and Activity of CD11b on Human Neutrophils
Anthony M. Mastrangelo, Thomas M. Jeitner and John W. Eaton

J Immunol October 15, 1998, 161 (8) 4268-4275;
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Expression and Participation of Eotaxin During Mycobacterial (Type 1) and Schistosomal (Type 2) Antigen-Elicited Granuloma Formation
Jeffrey H. Ruth, Nicholas W. Lukacs, Kelly S. Warmington, Tim J. Polak, Marie Burdick, Steven L. Kunkel, Robert M. Strieter and Stephen W. Chensue

J Immunol October 15, 1998, 161 (8) 4276-4282;
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Immunoregulatory Roles of IL-10 in Innate Immunity: IL-10 Inhibits Macrophage Production of IFN-γ-Inducing Factors but Enhances NK Cell Production of IFN-γ
Yoshimi Shibata, L. Ann Foster, Masashi Kurimoto, Haruki Okamura, Reiko M. Nakamura, Katsuhide Kawajiri, J. Paul Justice, Michael R. Van Scott, Quentin N. Myrvik and W. James Metzger

J Immunol October 15, 1998, 161 (8) 4283-4288;
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Virus-Induced Immunoinflammatory Lesions in the Absence of Viral Antigen Recognition
Shivaprakash Gangappa, John Sam Babu, Johnson Thomas, Massoud Daheshia and Barry T. Rouse

J Immunol October 15, 1998, 161 (8) 4289-4300;
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Effect of Cytotoxic Necrotizing Factor-1 on Actin Cytoskeleton in Human Monocytes: Role in the Regulation of Integrin-Dependent Phagocytosis
Christian Capo, Sonia Meconi, Muriel-Véronique Sanguedolce, Nathalie Bardin, Gilles Flatau, Patrice Boquet and Jean-Louis Mege

J Immunol October 15, 1998, 161 (8) 4301-4308;
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HIV-1 Envelope gp120 Inhibits the Monocyte Response to Chemokines Through CD4 Signal-Dependent Chemokine Receptor Down-Regulation
Ji Ming Wang, Hirotsugu Ueda, O. M. Zack Howard, Michael C. Grimm, Oleg Chertov, Xiaoqi Gong, Wanghua Gong, James H. Resau, Christopher C. Broder, Gerald Evans, Larry O. Arthur, Francis W. Ruscetti and Joost J. Oppenheim

J Immunol October 15, 1998, 161 (8) 4309-4317;
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Factor Xa Induces Cytokine Production and Expression of Adhesion Molecules by Human Umbilical Vein Endothelial Cells
Nicole H. M. Senden, Trudi M. A. A. Jeunhomme, Johan W. M. Heemskerk, Rob Wagenvoord, Cornelis van’t Veer, H. Coenraad Hemker and Wim A. Buurman

J Immunol October 15, 1998, 161 (8) 4318-4324;
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Differential Binding of IgG and of a HIV gp41 Peptide by the B Chain and A Chain Globular Head Sequences of C1q, Respectively
Mihaela S. Kojouharova, Ivelin D. Panchev, Magdalena I. Tchorbadjieva, Kenneth B. M. Reid and Hans-Jürgen Hoppe

J Immunol October 15, 1998, 161 (8) 4325-4331;
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Ca²⁺-Dependent Production and Release of IL-8 in Human Neutrophils
Douglas B. Kuhns, Howard A. Young, Elaine K. Gallin and John I. Gallin

J Immunol October 15, 1998, 161 (8) 4332-4339;
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Interaction with Secretory Component Stimulates Effector Functions of Human Eosinophils But Not of Neutrophils
Youichi Motegi and Hirohito Kita

J Immunol October 15, 1998, 161 (8) 4340-4346;
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A Chondroitin Sulfate Proteoglycan on Human Neutrophils Specifically Binds Platelet Factor 4 and Is Involved in Cell Activation
Frank Petersen, Lothar Bock, Hans-Dieter Flad and Ernst Brandt

J Immunol October 15, 1998, 161 (8) 4347-4355;
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Oxidized α₂-Macroglobulin (α₂M) Differentially Regulates Receptor Binding by Cytokines/Growth Factors: Implications for Tissue Injury and Repair Mechanisms in Inflammation
Sean M. Wu, Dhavalkumar D. Patel and Salvatore V. Pizzo

J Immunol October 15, 1998, 161 (8) 4356-4365;
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Mutations in the Activation Loop Tyrosines of Protein Tyrosine Kinase Syk Abrogate Intracellular Signaling But Not Kinase Activity
Juan Zhang, Teruaki Kimura and Reuben P. Siraganian

J Immunol October 15, 1998, 161 (8) 4366-4374;
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Products of Sphingolipid Catabolism Block Activation of the p21-Activated Protein Kinases in Neutrophils
Jian P. Lian, RiYun Huang, Dwight Robinson and John A. Badwey

J Immunol October 15, 1998, 161 (8) 4375-4381;
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Endothelial Cell Activation by Leukocyte Microparticles
Mehdi Mesri and Dario C. Altieri

J Immunol October 15, 1998, 161 (8) 4382-4387;
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Complement-Induced Expression of Chemokine Genes in Endothelium: Regulation by IL-1-Dependent and -Independent Mechanisms
Rathinam S. Selvan, Homi B. Kapadia and Jeffrey L. Platt

J Immunol October 15, 1998, 161 (8) 4388-4395;
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Endothelial Selectins and α₄ Integrins Regulate Independent Pathways of T Lymphocyte Recruitment in the Pulmonary Immune Response
Frances M. Wolber, Jeffrey L. Curtis, Petr Mály, Robert J. Kelly, Peter Smith, T. A. Yednock, John B. Lowe and Lloyd M. Stoolman

J Immunol October 15, 1998, 161 (8) 4396-4403;

CLINICAL IMMUNOLOGY

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Detection of HIV-1-Specific CTLs in the Semen of HIV-Infected Individuals
Alison J. Quayle, Wanda M. P. Coston, Alicja K. Trocha, Spyros A. Kalams, Kenneth H. Mayer and Deborah J. Anderson

J Immunol October 15, 1998, 161 (8) 4406-4410;
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Localization of Quantitative Trait Loci Regulating Adjuvant-Induced Arthritis in Rats: Evidence for Genetic Factors Common to Multiple Autoimmune Diseases
Yutaka Kawahito, Grant W. Cannon, Pércío S. Gulko, Elaine F. Remmers, Ryan E. Longman, Van R. Reese, Jianping Wang, Marie M. Griffiths and Ronald L. Wilder

J Immunol October 15, 1998, 161 (8) 4411-4419;
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IL-10 Impacts Autoimmune Diabetes Via a CD8⁺T Cell Pathway Circumventing the Requirement for CD4⁺T and B Lymphocytes
Balaji Balasa, Joanna D. Davies, Jae Lee, Augusta Good, Brian T. Yeung and Nora Sarvetnick

J Immunol October 15, 1998, 161 (8) 4420-4427;
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Selective Accumulation of Related CD4⁺ T Cell Clones in the Synovial Fluid of Patients with Rheumatoid Arthritis
Christopher C. Striebich, Michael T. Falta, Yi Wang, Jerry Bill and Brian L. Kotzin

J Immunol October 15, 1998, 161 (8) 4428-4436;
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Differential Expression of Inflammatory Cytokines Parallels Progression of Central Nervous System Pathology in Two Clinically Distinct Models of Multiple Sclerosis
Wendy Smith Begolka, Carol L. Vanderlugt, Sandra M. Rahbe and Stephen D. Miller

J Immunol October 15, 1998, 161 (8) 4437-4446;
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Human Class I Supertypes and CTL Repertoires Extend to Chimpanzees
Roberto Bertoni, Alessandro Sette, John Sidney, Luca G. Guidotti, Max Shapiro, Robert Purcell and Francis V. Chisari

J Immunol October 15, 1998, 161 (8) 4447-4455;

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Table of Contents

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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