Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist.

R T Lee; W H Briggs; G C Cheng; H B Rossiter; P Libby; T Kupper

Article Information

vol. 159 no. 10 5084-5088

PubMed

9366437

Published By

The American Association of Immunologists, Inc.

Print ISSN

0022-1767

Online ISSN

1550-6606

History

Published online November 15, 1997.

Author Information

R T Lee,
W H Briggs,
G C Cheng,
H B Rossiter,
P Libby and
T Kupper

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. RTLEE@BICS.BWH.HARVARD.EDU

Article usage

Article usage: November 2000 to May 2022

	Abstract	Full	Pdf
Nov 2000	1	0	0
Total 2000	1	0	0
Jan 2001	1	0	0
May 2001	1	0	0
Jun 2001	1	0	0
Jul 2001	1	0	0
Oct 2001	1	0	0
Nov 2001	2	0	2
Total 2001	7	0	2
Jan 2002	1	0	4
Feb 2002	0	0	1
Mar 2002	1	0	6
Apr 2002	1	0	1
May 2002	0	0	1
Jun 2002	0	0	1
Jul 2002	0	0	8
Aug 2002	1	0	1
Sep 2002	0	0	4
Oct 2002	2	0	3
Nov 2002	1	0	2
Dec 2002	1	0	1
Total 2002	8	0	33
Jan 2003	0	0	5
Feb 2003	2	0	5
Mar 2003	3	0	3
May 2003	0	0	9
Jun 2003	16	0	5
Jul 2003	245	0	4
Aug 2003	4	0	6
Sep 2003	7	0	4
Oct 2003	3	0	0
Nov 2003	3	0	0
Dec 2003	5	0	5
Total 2003	288	0	46
Jan 2004	3	0	5
Feb 2004	3	0	1
Mar 2004	6	0	3
Apr 2004	8	0	1
May 2004	4	0	1
Jun 2004	4	0	1
Jul 2004	12	0	4
Aug 2004	11	0	3
Sep 2004	8	0	10
Oct 2004	8	0	0
Nov 2004	7	0	3
Dec 2004	5	0	9
Total 2004	79	0	41
Jan 2005	7	0	5
Feb 2005	6	0	6
Mar 2005	11	1	2
Apr 2005	1	1	3
May 2005	5	2	7
Jun 2005	5	4	4
Jul 2005	5	2	0
Aug 2005	5	2	6
Sep 2005	2	2	6
Oct 2005	4	2	1
Nov 2005	2	1	4
Dec 2005	1	1	4
Total 2005	54	18	48
Jan 2006	4	0	2
Feb 2006	4	0	1
Mar 2006	1	0	5
Apr 2006	2	0	11
May 2006	1	0	6
Jun 2006	0	0	3
Jul 2006	1	0	3
Aug 2006	4	0	3
Sep 2006	3	0	4
Oct 2006	2	0	2
Nov 2006	4	0	6
Total 2006	26	0	46
Jan 2007	5	0	8
Feb 2007	3	0	7
Mar 2007	5	0	8
Apr 2007	2	0	3
May 2007	2	0	2
Jun 2007	4	0	7
Jul 2007	1	0	2
Aug 2007	1	0	7
Sep 2007	3	0	4
Oct 2007	4	0	5
Nov 2007	4	0	6
Dec 2007	0	0	8
Total 2007	34	0	67
Jan 2008	5	0	6
Feb 2008	6	0	5
Mar 2008	5	0	4
Apr 2008	4	0	4
May 2008	3	0	3
Jun 2008	5	0	3
Jul 2008	1	0	3
Aug 2008	3	0	1
Sep 2008	3	0	0
Oct 2008	3	0	4
Nov 2008	14	0	8
Dec 2008	4	0	10
Total 2008	56	0	51
Jan 2009	4	0	2
Feb 2009	11	0	5
Mar 2009	3	0	4
Apr 2009	6	0	1
May 2009	4	0	2
Jun 2009	17	0	3
Jul 2009	4	0	6
Aug 2009	3	0	4
Sep 2009	4	0	3
Oct 2009	3	0	6
Nov 2009	4	0	16
Dec 2009	1	0	9
Total 2009	64	0	61
Jan 2010	2	0	6
Feb 2010	3	0	2
Mar 2010	5	0	3
Apr 2010	3	0	5
May 2010	2	0	0
Jun 2010	2	0	0
Jul 2010	11	0	3
Aug 2010	13	0	2
Sep 2010	21	0	4
Oct 2010	13	0	7
Nov 2010	8	0	2
Dec 2010	2	0	8
Total 2010	85	0	42
Jan 2011	10	0	15
Feb 2011	8	0	10
Mar 2011	13	0	3
Apr 2011	11	0	6
May 2011	4	0	5
Jun 2011	8	0	2
Jul 2011	7	0	2
Aug 2011	6	0	3
Sep 2011	8	0	0
Oct 2011	8	0	3
Nov 2011	7	0	2
Dec 2011	5	0	1
Total 2011	95	0	52
Jan 2012	8	0	3
Feb 2012	6	0	4
Mar 2012	5	0	0
Apr 2012	7	0	9
May 2012	8	0	6
Jun 2012	9	0	3
Jul 2012	7	0	5
Aug 2012	9	0	4
Oct 2012	6	0	6
Nov 2012	0	0	2
Dec 2012	3	0	3
Total 2012	68	0	45
Jan 2013	9	0	3
Feb 2013	6	0	2
Mar 2013	7	0	7
Apr 2013	4	0	1
May 2013	4	0	1
Jun 2013	4	0	1
Jul 2013	4	0	3
Aug 2013	3	0	2
Sep 2013	3	0	3
Oct 2013	6	0	0
Nov 2013	5	0	2
Dec 2013	1	0	1
Total 2013	56	0	26
Jan 2014	3	0	8
Feb 2014	1	0	3
Mar 2014	17	0	2
Apr 2014	15	0	3
May 2014	2	0	6
Jun 2014	9	0	3
Jul 2014	20	0	0
Aug 2014	10	0	4
Sep 2014	14	0	7
Oct 2014	2	0	3
Nov 2014	5	0	3
Dec 2014	5	0	4
Total 2014	103	0	46
Jan 2015	4	0	0
Feb 2015	3	0	3
Mar 2015	7	0	0
Apr 2015	12	0	1
May 2015	1	0	2
Jun 2015	3	0	2
Jul 2015	5	0	7
Aug 2015	74	0	1
Sep 2015	13	0	0
Oct 2015	5	0	2
Nov 2015	10	0	5
Dec 2015	3	0	2
Total 2015	140	0	25
Jan 2016	76	0	1
Feb 2016	2	0	4
Mar 2016	9	0	5
Apr 2016	4	0	1
May 2016	3	0	0
Jun 2016	3	0	1
Jul 2016	4	0	1
Aug 2016	1	0	0
Sep 2016	3	0	1
Oct 2016	13	0	0
Nov 2016	62	0	0
Dec 2016	8	0	1
Total 2016	188	0	15
Jan 2017	17	0	4
Feb 2017	18	0	5
Mar 2017	8	0	3
Apr 2017	5	0	2
May 2017	5	0	1
Jun 2017	15	0	3
Jul 2017	3	0	0
Aug 2017	3	0	0
Sep 2017	5	0	2
Oct 2017	8	0	2
Nov 2017	6	0	2
Dec 2017	3	0	6
Total 2017	96	0	30
Jan 2018	5	0	2
Feb 2018	12	0	0
Mar 2018	16	0	4
Apr 2018	4	0	1
May 2018	10	0	0
Jun 2018	21	0	3
Jul 2018	8	0	1
Aug 2018	18	0	4
Sep 2018	22	0	1
Oct 2018	7	0	3
Nov 2018	21	0	4
Dec 2018	5	0	0
Total 2018	149	0	23
Jan 2019	13	0	2
Feb 2019	2	0	2
Mar 2019	7	0	0
Apr 2019	2	0	1
May 2019	9	0	2
Jun 2019	2	0	0
Jul 2019	9	0	1
Aug 2019	14	0	2
Sep 2019	3	0	0
Oct 2019	23	0	3
Nov 2019	17	0	6
Dec 2019	8	0	1
Total 2019	109	0	20
Jan 2020	8	0	0
Feb 2020	4	0	1
Mar 2020	13	0	2
Apr 2020	13	0	3
May 2020	9	0	3
Jun 2020	7	0	1
Jul 2020	6	0	4
Aug 2020	1	0	0
Sep 2020	12	0	1
Oct 2020	3	0	0
Nov 2020	20	0	0
Dec 2020	21	0	3
Total 2020	117	0	18
Jan 2021	11	0	0
Feb 2021	5	0	0
Mar 2021	16	0	3
Apr 2021	48	0	1
May 2021	15	0	3
Jun 2021	11	0	1
Jul 2021	6	0	0
Aug 2021	4	0	1
Sep 2021	6	0	2
Oct 2021	6	0	1
Nov 2021	18	0	1
Dec 2021	9	0	1
Total 2021	155	0	14
Jan 2022	8	0	5
Feb 2022	13	0	0
Mar 2022	6	0	1
Apr 2022	10	0	1
May 2022	10	0	0
Total 2022	47	0	7
Total	2025	18	758

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Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist.

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Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist.

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