An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

J S Orange; C A Biron

Article Information

vol. 156 no. 3 1138-1142

PubMed

8557990

Published By

The American Association of Immunologists, Inc.

Print ISSN

0022-1767

Online ISSN

1550-6606

History

Published online February 1, 1996.

Author Information

J S Orange and
C A Biron

Division of Biology and Medicine Brown University, Providence, RI 02912, USA.

Article usage

Article usage: October 2000 to August 2020

	Abstract	Full	Pdf
Oct 2000	5	0	0
Nov 2000	3	0	0
Dec 2000	1	0	0
Total 2000	9	0	0
Jan 2001	8	0	0
Feb 2001	2	0	0
Mar 2001	4	0	0
Apr 2001	3	0	0
May 2001	2	0	0
Jun 2001	2	0	0
Jul 2001	5	0	0
Aug 2001	1	0	0
Sep 2001	4	0	0
Oct 2001	1	0	9
Nov 2001	2	0	0
Dec 2001	5	0	4
Total 2001	39	0	13
Jan 2002	1	0	5
Feb 2002	2	0	6
Mar 2002	0	0	5
Apr 2002	1	0	12
May 2002	3	0	9
Jun 2002	1	0	9
Jul 2002	1	0	8
Aug 2002	3	0	12
Sep 2002	0	0	3
Oct 2002	4	0	6
Nov 2002	10	0	5
Dec 2002	3	1	8
Total 2002	29	1	88
Jan 2003	0	0	10
Feb 2003	1	0	16
Mar 2003	5	0	11
Apr 2003	8	0	5
May 2003	2	0	10
Jun 2003	4	0	4
Jul 2003	0	0	4
Aug 2003	8	0	2
Sep 2003	12	0	13
Oct 2003	4	0	5
Nov 2003	9	0	3
Dec 2003	5	0	4
Total 2003	58	0	87
Jan 2004	9	0	9
Feb 2004	3	0	6
Mar 2004	5	0	9
Apr 2004	15	0	6
May 2004	11	0	10
Jun 2004	7	0	5
Jul 2004	6	0	3
Aug 2004	12	0	8
Sep 2004	5	0	5
Oct 2004	2	0	3
Nov 2004	7	0	7
Dec 2004	11	0	10
Total 2004	93	0	81
Jan 2005	5	0	10
Feb 2005	9	0	2
Mar 2005	4	0	7
Apr 2005	5	0	10
May 2005	2	0	22
Jun 2005	5	0	11
Jul 2005	4	0	9
Aug 2005	9	0	12
Sep 2005	4	0	17
Oct 2005	10	0	8
Nov 2005	7	0	4
Dec 2005	7	0	10
Total 2005	71	0	122
Jan 2006	8	0	9
Feb 2006	1	0	6
Mar 2006	8	0	7
Apr 2006	6	0	8
May 2006	2	0	12
Jun 2006	3	0	5
Jul 2006	3	0	7
Aug 2006	4	0	7
Sep 2006	7	0	2
Oct 2006	6	0	1
Nov 2006	14	0	9
Dec 2006	6	0	12
Total 2006	68	0	85
Jan 2007	8	0	10
Feb 2007	9	0	8
Mar 2007	14	0	9
Apr 2007	0	0	4
May 2007	2	0	6
Jun 2007	0	0	6
Jul 2007	7	0	11
Aug 2007	5	0	8
Sep 2007	6	0	9
Oct 2007	7	0	9
Nov 2007	8	0	10
Dec 2007	3	0	3
Total 2007	69	0	93
Jan 2008	7	0	3
Feb 2008	12	0	3
Mar 2008	9	0	10
Apr 2008	8	0	6
May 2008	3	0	11
Jun 2008	18	0	12
Jul 2008	13	0	10
Aug 2008	12	0	7
Sep 2008	12	0	9
Oct 2008	7	0	8
Nov 2008	8	0	6
Dec 2008	8	0	9
Total 2008	117	0	94
Jan 2009	18	0	11
Feb 2009	13	0	7
Mar 2009	8	0	2
Apr 2009	9	0	6
May 2009	9	0	7
Jun 2009	14	0	10
Jul 2009	2	0	5
Aug 2009	10	0	9
Sep 2009	7	0	4
Oct 2009	7	0	3
Nov 2009	9	0	8
Dec 2009	2	0	8
Total 2009	108	0	80
Jan 2010	9	0	6
Feb 2010	15	0	5
Mar 2010	9	0	7
Apr 2010	7	0	8
May 2010	3	0	6
Jun 2010	6	0	6
Jul 2010	7	0	10
Aug 2010	4	0	12
Sep 2010	9	0	7
Oct 2010	8	0	8
Nov 2010	8	0	23
Dec 2010	10	0	4
Total 2010	95	0	102
Jan 2011	8	0	16
Feb 2011	12	0	15
Mar 2011	31	0	24
Apr 2011	26	0	23
May 2011	24	0	4
Jun 2011	22	0	6
Jul 2011	34	0	29
Aug 2011	19	0	7
Sep 2011	22	0	4
Oct 2011	15	0	9
Nov 2011	16	0	5
Dec 2011	21	0	6
Total 2011	250	0	148
Jan 2012	14	0	9
Feb 2012	35	0	6
Mar 2012	24	0	10
Apr 2012	22	0	6
May 2012	13	0	9
Jun 2012	24	0	8
Jul 2012	29	0	10
Aug 2012	15	0	15
Sep 2012	14	0	8
Oct 2012	17	0	13
Nov 2012	11	0	15
Dec 2012	12	0	5
Total 2012	230	0	114
Jan 2013	6	0	3
Feb 2013	8	0	8
Mar 2013	12	0	4
Apr 2013	10	0	9
May 2013	13	0	5
Jun 2013	12	0	13
Jul 2013	8	0	5
Aug 2013	6	0	3
Sep 2013	11	0	7
Oct 2013	13	0	32
Nov 2013	17	0	7
Dec 2013	13	0	4
Total 2013	129	0	100
Jan 2014	15	0	8
Feb 2014	15	0	5
Mar 2014	8	0	9
Apr 2014	8	0	3
May 2014	5	0	9
Jun 2014	19	0	3
Jul 2014	16	0	15
Aug 2014	1	0	8
Sep 2014	6	0	4
Oct 2014	11	0	12
Nov 2014	9	0	9
Dec 2014	9	0	3
Total 2014	122	0	88
Jan 2015	15	0	5
Feb 2015	11	0	13
Mar 2015	13	0	6
Apr 2015	12	0	10
May 2015	11	0	8
Jun 2015	10	0	4
Jul 2015	10	0	2
Aug 2015	16	0	5
Sep 2015	31	0	6
Oct 2015	17	0	10
Nov 2015	16	0	7
Dec 2015	10	0	0
Total 2015	172	0	76
Jan 2016	11	0	3
Feb 2016	20	0	11
Mar 2016	31	0	2
Apr 2016	15	0	4
May 2016	5	0	3
Jun 2016	11	0	17
Jul 2016	14	0	4
Aug 2016	5	0	3
Sep 2016	15	0	6
Oct 2016	12	0	7
Nov 2016	15	0	7
Dec 2016	17	0	5
Total 2016	171	0	72
Jan 2017	30	0	4
Feb 2017	10	0	1
Mar 2017	35	0	3
Apr 2017	29	0	10
May 2017	24	0	5
Jun 2017	27	0	4
Jul 2017	20	0	2
Aug 2017	21	0	3
Sep 2017	30	0	3
Oct 2017	21	0	3
Nov 2017	30	0	2
Dec 2017	18	0	3
Total 2017	295	0	43
Jan 2018	18	0	13
Feb 2018	11	0	4
Mar 2018	44	0	10
Apr 2018	13	0	3
May 2018	30	0	6
Jun 2018	13	0	1
Jul 2018	11	0	1
Aug 2018	13	0	3
Sep 2018	19	0	7
Oct 2018	35	0	8
Nov 2018	29	0	5
Dec 2018	12	0	3
Total 2018	248	0	64
Jan 2019	14	0	3
Feb 2019	52	0	18
Mar 2019	10	0	2
Apr 2019	8	0	2
May 2019	17	0	5
Jun 2019	10	0	2
Jul 2019	19	0	0
Aug 2019	14	0	2
Sep 2019	31	0	8
Oct 2019	32	0	3
Nov 2019	27	0	4
Dec 2019	23	0	1
Total 2019	257	0	50
Jan 2020	55	0	1
Feb 2020	10	0	1
Mar 2020	23	0	6
Apr 2020	53	0	6
May 2020	18	0	6
Jun 2020	26	0	2
Jul 2020	30	0	4
Aug 2020	12	0	1
Total 2020	227	0	27
Total	2857	1	1627

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An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

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Article usage: October 2000 to August 2020

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An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

Article Information

Author Information

Article usage

Article usage: October 2000 to August 2020

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