Mechanisms of T cell activation by the calcium ionophore ionomycin.

T Chatila; L Silverman; R Miller; R Geha

Article Information

vol. 143 no. 4 1283-1289

PubMed

2545785

Published By

The American Association of Immunologists, Inc.

Print ISSN

0022-1767

Online ISSN

1550-6606

History

Published online August 15, 1989.

Author Information

T Chatila,
L Silverman,
R Miller and
R Geha

Division of Immunology, Children's Hospital, Boston, Massachusetts 02115.

Article usage

Article usage: October 2000 to June 2022

	Abstract	Full	Pdf
Oct 2000	3	0	0
Nov 2000	2	0	0
Total 2000	5	0	0
Jan 2001	1	0	0
Mar 2001	1	0	0
Jun 2001	1	0	0
Total 2001	3	0	0
Jan 2002	3	0	2
Feb 2002	0	0	1
Mar 2002	0	0	1
Jul 2002	1	0	0
Sep 2002	1	0	2
Nov 2002	0	0	1
Dec 2002	1	0	0
Total 2002	6	0	7
Jan 2003	1	0	0
Mar 2003	0	0	1
May 2003	1	0	2
Jul 2003	1	0	0
Aug 2003	6	0	2
Sep 2003	4	0	6
Oct 2003	4	0	5
Nov 2003	7	0	2
Dec 2003	3	0	0
Total 2003	27	0	18
Jan 2004	4	0	1
Feb 2004	2	0	0
Mar 2004	2	0	2
Apr 2004	2	0	1
May 2004	4	0	0
Jun 2004	5	0	0
Jul 2004	6	0	2
Aug 2004	12	0	15
Sep 2004	7	0	0
Oct 2004	39	0	18
Nov 2004	25	0	6
Dec 2004	18	0	18
Total 2004	126	0	63
Jan 2005	30	0	20
Feb 2005	48	0	14
Mar 2005	33	1	24
Apr 2005	61	0	28
May 2005	57	0	28
Jun 2005	74	0	28
Jul 2005	63	0	15
Aug 2005	34	0	12
Sep 2005	57	0	18
Oct 2005	68	0	23
Nov 2005	147	0	53
Dec 2005	73	0	15
Total 2005	745	1	278
Jan 2006	102	0	29
Feb 2006	94	0	21
Mar 2006	98	0	35
Apr 2006	98	0	24
May 2006	121	0	36
Jun 2006	117	0	36
Jul 2006	95	0	26
Aug 2006	116	0	42
Sep 2006	108	0	31
Oct 2006	172	0	50
Nov 2006	141	0	39
Dec 2006	74	0	20
Total 2006	1336	0	389
Jan 2007	107	0	30
Feb 2007	93	0	34
Mar 2007	101	0	41
Apr 2007	92	0	42
May 2007	103	0	47
Jun 2007	69	0	43
Jul 2007	70	0	33
Aug 2007	69	0	43
Sep 2007	60	0	24
Oct 2007	98	0	46
Nov 2007	74	0	32
Dec 2007	83	0	29
Total 2007	1019	0	444
Jan 2008	119	0	64
Feb 2008	110	0	44
Mar 2008	116	0	52
Apr 2008	93	0	32
May 2008	122	0	45
Jun 2008	79	0	43
Jul 2008	101	0	51
Aug 2008	104	0	54
Sep 2008	77	0	45
Oct 2008	116	0	69
Nov 2008	100	0	53
Dec 2008	63	0	46
Total 2008	1200	0	598
Jan 2009	81	0	52
Feb 2009	88	0	63
Mar 2009	117	0	78
Apr 2009	96	0	53
May 2009	80	0	65
Jun 2009	105	0	91
Jul 2009	102	0	105
Aug 2009	124	0	105
Sep 2009	101	0	95
Oct 2009	124	0	123
Nov 2009	124	0	95
Dec 2009	93	0	64
Total 2009	1235	0	989
Jan 2010	97	0	71
Feb 2010	122	0	114
Mar 2010	154	0	114
Apr 2010	145	0	112
May 2010	139	0	124
Jun 2010	133	0	167
Jul 2010	136	0	139
Aug 2010	119	0	114
Sep 2010	141	0	144
Oct 2010	155	0	96
Nov 2010	197	0	159
Dec 2010	91	0	130
Total 2010	1629	0	1484
Jan 2011	120	0	137
Feb 2011	139	0	195
Mar 2011	206	0	205
Apr 2011	175	0	236
May 2011	140	0	141
Jun 2011	178	0	210
Jul 2011	144	0	199
Aug 2011	183	0	187
Sep 2011	146	0	163
Oct 2011	248	0	277
Nov 2011	285	0	250
Dec 2011	202	0	196
Total 2011	2166	0	2396
Jan 2012	212	0	242
Feb 2012	206	0	286
Mar 2012	244	4	302
Apr 2012	191	0	211
May 2012	192	0	191
Jun 2012	116	0	102
Jul 2012	64	0	39
Aug 2012	39	0	45
Sep 2012	40	0	27
Oct 2012	48	0	40
Nov 2012	35	0	22
Dec 2012	29	0	17
Total 2012	1416	4	1524
Jan 2013	33	0	27
Feb 2013	45	0	43
Mar 2013	40	0	46
Apr 2013	60	0	63
May 2013	41	0	61
Jun 2013	33	0	60
Jul 2013	23	0	62
Aug 2013	23	0	49
Sep 2013	19	0	58
Oct 2013	39	0	83
Nov 2013	24	0	56
Dec 2013	20	2	44
Total 2013	400	2	652
Jan 2014	31	1	78
Feb 2014	24	0	58
Mar 2014	41	0	96
Apr 2014	38	0	90
May 2014	26	0	70
Jun 2014	24	0	91
Jul 2014	22	0	60
Aug 2014	24	0	60
Sep 2014	132	0	82
Oct 2014	24	0	70
Nov 2014	55	0	66
Dec 2014	38	0	65
Total 2014	479	1	886
Jan 2015	24	0	74
Feb 2015	32	0	97
Mar 2015	82	0	108
Apr 2015	36	0	77
May 2015	112	0	66
Jun 2015	56	0	101
Jul 2015	48	0	90
Aug 2015	74	0	95
Sep 2015	48	0	57
Oct 2015	101	0	126
Nov 2015	52	0	116
Dec 2015	54	0	56
Total 2015	719	0	1063
Jan 2016	59	0	73
Feb 2016	90	0	80
Mar 2016	133	0	284
Apr 2016	48	0	114
May 2016	60	0	98
Jun 2016	77	0	100
Jul 2016	80	0	97
Aug 2016	34	0	89
Sep 2016	90	0	82
Oct 2016	72	0	52
Nov 2016	52	0	75
Dec 2016	49	0	64
Total 2016	844	0	1208
Jan 2017	193	0	72
Feb 2017	277	0	55
Mar 2017	293	0	82
Apr 2017	293	0	68
May 2017	311	0	88
Jun 2017	276	0	62
Jul 2017	273	0	61
Aug 2017	268	0	68
Sep 2017	182	0	45
Oct 2017	249	0	71
Nov 2017	296	0	68
Dec 2017	265	0	49
Total 2017	3176	0	789
Jan 2018	253	0	67
Feb 2018	279	0	65
Mar 2018	244	0	47
Apr 2018	221	0	53
May 2018	270	0	62
Jun 2018	190	0	45
Jul 2018	230	0	56
Aug 2018	201	0	50
Sep 2018	153	0	35
Oct 2018	221	0	47
Nov 2018	212	0	30
Dec 2018	151	0	17
Total 2018	2625	0	574
Jan 2019	248	0	63
Feb 2019	182	0	44
Mar 2019	195	0	48
Apr 2019	206	0	53
May 2019	207	0	54
Jun 2019	179	0	57
Jul 2019	240	0	59
Aug 2019	222	0	41
Sep 2019	217	0	38
Oct 2019	215	0	44
Nov 2019	185	0	35
Dec 2019	161	0	50
Total 2019	2457	0	586
Jan 2020	167	0	38
Feb 2020	244	0	49
Mar 2020	165	0	26
Apr 2020	180	0	34
May 2020	200	0	34
Jun 2020	131	0	32
Jul 2020	77	0	16
Aug 2020	76	0	13
Sep 2020	91	0	10
Oct 2020	141	0	12
Nov 2020	105	0	11
Dec 2020	156	0	17
Total 2020	1733	0	292
Jan 2021	106	0	19
Feb 2021	123	0	18
Mar 2021	142	0	18
Apr 2021	156	0	25
May 2021	182	0	25
Jun 2021	178	0	26
Jul 2021	142	0	22
Aug 2021	95	0	20
Sep 2021	120	0	21
Oct 2021	119	0	13
Nov 2021	122	0	20
Dec 2021	91	0	19
Total 2021	1576	0	246
Jan 2022	113	0	15
Feb 2022	145	0	16
Mar 2022	169	0	23
Apr 2022	114	0	14
May 2022	169	0	24
Jun 2022	170	0	16
Total 2022	880	0	108
Total	25802	8	14594

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Mechanisms of T cell activation by the calcium ionophore ionomycin.

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Mechanisms of T cell activation by the calcium ionophore ionomycin.

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