Abstract
The sea robin (Prionotus evolans), a representative teleost fish, was found to undergo the hapten-carrier effect, suggestive of T-B cell cooperativity, in vivo with dinitrophenyl as the hapten and bovine γ-globulin or bovine serum albumin as carriers. In contrast to mammalian systems, the secondary anti-hapten response in the sea robin was found to involve exclusively high molecular weight antibody.
Footnotes
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↵2 Address correspondence to: L. W. Clem, University of Florida, J. Hillis Miller Health Center, College of Medicine, Box 727, Gainesville, Florida 32610.
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↵1 This work was supported by Grants GB29095 from the National Science Foundation and 5-TI-AIO128 and GM00265-14 from the National Institutes of Health.
- Received October 2, 1974.
- Copyright © 1975 by The American Association of Immunologists, Inc.
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