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The Cytotoxic Effector Potential of Some Common Non-Lymphoid Tumors and Cultured Cell Lines with Phytohemagglutinin and Heterologous Anti-Erythrocyte Antisera

A. V. Muchmore, D. L. Nelson and R. M. Blaese
J Immunol March 1, 1975, 114 (3) 1001-1003;
A. V. Muchmore
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D. L. Nelson
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R. M. Blaese
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Abstract

We have found that a) phytohemagglutinin can induce red blood cell cytolysis by non-lymphoid tumors and cell lines, b) rabbit anti-chicken red blood cell antibody but not turkey anti-chicken red blood cell antibody can mediate an antibody-directed cellular cytotoxicity type of cytotoxicity utilizing P815Y mastocytoma cells or rat embryo fibroblasts as effectors, and c) none of these cell line effectors was capable of killing metabolically active cultured cell line targets in the presence of phytohemagglutinin.

  • Received September 16, 1974.
  • Copyright © 1975 by The American Association of Immunologists, Inc.

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The Journal of Immunology
Vol. 114, Issue 3
1 Mar 1975
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The Cytotoxic Effector Potential of Some Common Non-Lymphoid Tumors and Cultured Cell Lines with Phytohemagglutinin and Heterologous Anti-Erythrocyte Antisera
A. V. Muchmore, D. L. Nelson, R. M. Blaese
The Journal of Immunology March 1, 1975, 114 (3) 1001-1003;

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The Cytotoxic Effector Potential of Some Common Non-Lymphoid Tumors and Cultured Cell Lines with Phytohemagglutinin and Heterologous Anti-Erythrocyte Antisera
A. V. Muchmore, D. L. Nelson, R. M. Blaese
The Journal of Immunology March 1, 1975, 114 (3) 1001-1003;
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