Abstract
Unfractionated and T cell-enriched populations from spleens of mice immunized with Sinbdis virus confer cross-protection against Semliki forest virus challenge in recipient mice. Both Group A viruses are serologically related, but not by tests for cross-neutralizing antibody. The protection in mice persisted for three consecutive cell passages in uninfected mice. The results suggest that cell-mediated immunity accounts for cross-protection.
- Received September 6, 1974.
- Copyright © 1975 by The American Association of Immunologists, Inc.
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Preliminary Evidence for Cell-Mediated Immunity in Cross-Protection Among Group A Arboviruses
