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Complement Receptors on Cell Membranes

I. Evidence for Two Complement Receptors

Hidechika Okada and Kusuya Nishioka
J Immunol November 1, 1973, 111 (5) 1444-1449;
Hidechika Okada
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Kusuya Nishioka
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Abstract

On DEAE-cellulose column chromatography, two fractions were obtained from mouse plasma. One made EA(IgM)C42 reactive to human erythrocytes but not to Daudi cells, a cultured cell line derived from Burkitt lymphoma. The addition of the other fraction to these intermediate complexes of complement on cells diminished adherence to human erythrocytes but generated adherence to Daudi cells. From these results we conclude that the receptors on human erythrocytes and on Daudi cells react differently with the intermediate complexes of complement.

Footnotes

  • ↵1 This work was supported by research grants from the Ministry of Health and the Ministry of Education of the Japanese Government.

  • Received June 4, 1973.
  • Copyright © 1973 by The American Association of Immunologists, Inc.

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The Journal of Immunology
Vol. 111, Issue 5
1 Nov 1973
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Complement Receptors on Cell Membranes
Hidechika Okada, Kusuya Nishioka
The Journal of Immunology November 1, 1973, 111 (5) 1444-1449;

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Complement Receptors on Cell Membranes
Hidechika Okada, Kusuya Nishioka
The Journal of Immunology November 1, 1973, 111 (5) 1444-1449;
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Print ISSN 0022-1767        Online ISSN 1550-6606