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The Immunogenicity of Adenovirus Type 5 Structural Proteins

A. T. Haase, V. Mautner and H. G. Pereira
J Immunol February 1, 1972, 108 (2) 483-485;
A. T. Haase
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V. Mautner
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H. G. Pereira
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Abstract

The immunogenicity of two adenovirus structural proteins, hexon and fiber of adenovirus type 5, has been investigated. The lowest dose of antigen capable of inducing a primary immune response in guinea pigs was found to be 1 ng and 100 ng, respectively, for the two antigens. The immunogenicity of adenovirus antigens is discussed with respect to antigens from other microorganisms and vaccination with virus subunits.

Footnotes

  • ↵1 This work was partly supported by a grant from The Anna Fuller Foundation.

  • Received July 29, 1971.
  • Copyright, 1972, by The Williams & Wilkins Company
  • Copyright © 1972 by The American Association of Immunologists, Inc.

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The Journal of Immunology
Vol. 108, Issue 2
1 Feb 1972
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The Immunogenicity of Adenovirus Type 5 Structural Proteins
A. T. Haase, V. Mautner, H. G. Pereira
The Journal of Immunology February 1, 1972, 108 (2) 483-485;

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The Immunogenicity of Adenovirus Type 5 Structural Proteins
A. T. Haase, V. Mautner, H. G. Pereira
The Journal of Immunology February 1, 1972, 108 (2) 483-485;
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Print ISSN 0022-1767        Online ISSN 1550-6606