Abstract
Double diffusion experiments with antibodies to single-stranded (s-s) DNA confirmed physicochemical data that adeno-associated satellite virions contain s-s DNA but the DNA extracted from such virions is double-stranded. Positive immunologic reactions of intact virions with sera from man and mouse with “autoimmune” disease and specifically immunized rabbits are consistent with the hypothetical role if viruses as immunogens or as the antigenic participants of immunecomplex vasculitis.
Footnotes
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↵1 Aided by Research Grants HE 05435 from the National Heart Institute, CA 04600 from the National Cancer Institute, National Institutes of Health, United States Public Health Service, and United States Public Health Service Research Grant AM 11170.
- Received May 18, 1970.
- Copyright © 1970 by The American Association of Immunologists, Inc.
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