Summary
Germ-free mice exposed to sheep RBC by the oral route displayed an immune response in extraintestinal lymphoid tissues. Such a response in the spleen and mesenteric lymph nodes was characterized by a high percentage of PFC of the IgA class, and is at variance with that found after parenteral immunization.
Footnotes
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↵1 This work was supported by CNEN-Euratom Association Contract. Publication No. 630 of the Euratom Biology Division.
- Copyright © 1970 by The American Association of Immunologists, Inc.
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Predominant Contribution of IgA Antibody-Forming Cells to an Immune Response Detected in Extraintestinal Lymphoid Tissues of Germ-free Mice Exposed to Antigen by the Oral Route
