Table I. NK3 IgG blocks killing of BZ198 by anti-NspA mAb 14C7
Condition% Mean Survival (± SEM)
C alone (20%)a139 (± 5.9)
C + 14C7 (12 μg/ml)b51 (± 5.5)
C + 14C7 (12 μg/ml) + HI-NK3b113 (± 4.9)c
C + 14C7 (12 μg/ml) + HI-NK3 minus IgGd61 (± 6.0)
C + 14C7 (24 μg/ml)d2 (± 0.5)
C + 14C7 (24 μg/ml) + HI-NK3d88 (± 10.5)
C + 14C7 (24 μg/ml) + HI-NK3 minus IgGd9 (± 2.5)
  • a Five experiments.

  • b Three experiments.

  • c p = 0.02 versus C + 14C7 (12 μg/ml).

  • d Two experiments.

  • C, complement; HI-NK3, heat-inactivated NK3.