Table II. Protection against B. abortus 544 in BALB/c mice immunized with L-Omp16 or U-Omp16 without adjuvant
Vaccine (n = 5)AdjuvantLog10 a CFU of B. abortus 544 at Spleen (mean ± SD)Units of Protection
L-Omp16None4.68 ± 0.55 b , d 1.59
U-Omp16None4.59 ± 0.42 b 1.68
B. abortus strain 19None3.98 ± 0.26 b 2.29
PBSNone6.27 ± 0.14 c 0
  • a The content of bacteria in spleens is represented as the mean log10 CFU ± SD per group.

  • b Significantly different from PBS-immunized mice; p < 0.01 estimated by Dunnett’s test.

  • c Significantly different from B. abortus strain 19 immunized mice; p < 0.01 estimated by Dunnett’s test.

  • d Significantly different from B. abortus strain 19 immunized mice; p < 0.05 estimated by Dunnett’s test.