Table II.

FACS analysis of activated IL-20R2+/+ or IL-20R2−/− T cellsa

Cell NumbersIFN-γ+IL-2+
CD4: +/+1.13 × 1051.5 × 1031.1 × 104
−/−1.67 × 1053.8 × 1033.5 × 104
CD8: +/+1.35 × 1053.6 × 1040.9 × 105
−/−1.83 × 1054.9 × 1041.4 × 105
  • a CD4 and CD8 T cells were isolated from IL-20R2−/− or IL-20R2+/+ spleen cells by MACS. Cells were analyzed after 3 days of culture with anti-CD3/CD28 beads (1 bead/cell). The table shows cell numbers as well as the proportion of IFN-γ- and IL-2-positive CD4 and CD8 T cells in IL-20R2−/− and in IL-20R2+/+ T cell cultures at day 3. One representative experiment of three is shown.