Table III.

Comparison of M2 genes expressed in HCMV-infected monocytes/macrophagesa

Category and Full Gene NameGene TitleProbe SetFold Change
Membrane receptors
 Chemokine (C-X-C motif) receptor 4CXCR4649_s_at−2.5
 Transforming growth factor, beta receptor II (70/80 kDa)TGFBR21814_at−2.7
 Histamine receptor H1HRH135384_atnc
 Toll-like receptor 5TLR534473_atnc
 Type I transmembrane C-type lectin receptor DCL-1DCL-134760_atnc
 Macrophage scavenger receptor 1MSR139981_atnc
 G protein-coupled receptor 105GPR10533462_atnc
 CD209 antigen-likeCD209L39270_atnc
 CD36 antigen (collagen type I receptor, thrombospondin receptor)CD3636656_atnc
 Mannose receptor, C type 1MRC136908_atnc
Cytokine and chemokines
 Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)CCL1832128_at39.4
 Chemokine (C-C motif) ligand 23CCL2336444_s_at3.5
 Insulin-like growth factor 1 (somatomedin C)IGF11501_atnc
 Chemokine (C-C motif) ligand 13CCL1337454_atnc
Solute carriers
 Solute carrier family 4, sodium bicarbonate cotransporter, member 7SLC4A734936_at−1.5
 Solute carrier family 38, member 6SLC38A636758_atnc
Enzymes
 Leukotriene A4 hydrolaseLTA4H38081_at−5.5
 Cathepsin CCTSC133_atnc
 Hexosaminidase B (beta polypeptide)HEXB34888_atnc
 Lipase A, lysosomal acid, cholesterol esterase (Wolman disease)LIPA38745_atnc
 Adenosine kinaseADK168_atnc
 Histamine N-methyltransferaseHNMT37604_atnc
 Tyrosylprotein sulfotransferase 2TPST235172_atnc
 Heparan sulfate (glucosamine) 3-O-sulfotransferase 1HS3ST141555_atnc
 Carbonic anhydrase IICA240095_atnc
 Arachidonate 15-lipoxygenaseALOX1534636_atnc
 Heparan sulfate (glucosamine) 3-O-sulfotransferase 1HS3ST141555_atnc
Extracellular matrix
 Transforming growth factor, beta 1 (Camurati-Engelmann disease)TGFB11830_s_at−1.6
 Fibrinogen-like 2FGL239593_at−6.7
 Selenoprotein P, plasma, 1SEPP134363_atnc
 Chimerin (chimaerin) 2CHN233244_atnc
 Fibronectin 1FN131719_atnc
DNA-binding factors
 Growth arrest-specific 7GAS733387_atnc
 Early growth response 2 (Krox-20 homolog, Drosophila)EGR237863_atnc
 V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)MAF41504_s_atnc
  • a Examined M2 genes are based on the transcriptional profiling work of Martinez et al. (47 ). nc, No change.