Table I.

Selected statistically significant monocyte mRNAs that increase or decrease ≥1.5-fold 4 hpi with HCMV

Category and Full Gene NameGene TitleProbe SetFold Change
Antiapoptotic factors
 Tumor necrosis factor (TNF superfamily, member 2)TNF1852_at14.6
 Secreted phosphoprotein 1SPP12092_s_at6.3
 Suppressor of cytokine signaling 3SOCS340968_at5.7
 BCL2-related protein A1BCL2A12002_s_at4.9
 Interleukin 10IL101548_s_at4.6
 Chemokine (C-C motif) ligand 2CCL234375_at4.1
 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2SERPINB237185_at4.0
 CASP8 and FADD-like apoptosis regulatorCFLAR1868_g_at4.0
 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9SERPINB934438_at3.9
 Tumor necrosis factor, alpha-induced protein 8TNFAIP833243_at3.6
 Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 (p105)NFKB11378_g_at3.3
 Tumor necrosis factor receptor superfamily, member 6TNFRSF61440_s_at3.1
 Tumor necrosis factor, alpha-induced protein 3TNFAIP3595_at2.9
 Heat shock 70 kDa protein 1AHSPA1A31692_at2.5
 Baculoviral IAP repeat-containing 3BIRC31717_s_at2.5
 Immediate early response 3IER31237_at2.4
 CASP8 and FADD-like apoptosis regulatorCFLAR32746_at2.3
 Heat shock 70 kDa protein 9B (mortalin-2)HSPA9B41510_s_at1.8
 Notch homolog 2 (Drosophila)NOTCH238083_at1.5
 V-rel reticuloendotheliosis viral oncogene homolog ARELA1271_g_at1.5
 Mucosa-associated lymphoid tissue lymphoma translocation gene 1MALT132350_at−1.6
 Transforming growth factor, beta 1 (Camurati-Engelmann disease)TGFB11830_s_at−1.6
 Histone deacetylase 1HDAC138771_at−1.7
 RAS p21 protein activator (GTPase-activating protein) 1RASA11675_at−2.0
 Annexin A4ANXA437374_at−2.3
 Dimethylarginine dimethylaminohydrolase 2DDAH238621_at−3.3
Antiviral response
 Chemokine (C-C motif) ligand 4CCL436674_at16.2
 Tumor necrosis factor (TNF superfamily, member 2)TNF1852_at14.6
 Interferon, alpha 10IFNA101075_f_at10.2
 Interferon, alpha 2IFNA21791_s_at8.0
 Chemokine (C-C motif) ligand 8CCL837823_at7.4
 Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)MX137014_at5.6
 Signal transducer and activator of transcription 1, 91 kDaSTAT133338_at5.2
 Interferon, alpha 1IFNA11666_at5.0
 Interferon, alpha-inducible protein (clone IFI-15K)G1P21107_s_at3.9
 Interferon-induced protein 35IFI35464_s_at3.0
 2′,5′-oligoadenylate synthetase 1, 40/46 kDaOAS138388_at3.0
 DnaJ (Hsp40) homolog, subfamily C, member 3DNAJC333208_at2.8
 Tripartite motif-containing 22TRIM2236825_at2.5
 Interferon-stimulated gene, 20 kDaISG2033304_at2.4
 Myxovirus (influenza virus) resistance 2 (mouse)MX2879_at2.3
 Interferon, gamma-inducible protein 16IFI161456_s_at2.2
 Interferon regulatory factor 7IRF736412_s_at2.1
 Signal transducer and activator of transcription 2, 113 kDaSTAT236770_at2.0
 Chemokine (C-C motif) ligand 5CCL51404_r_at1.8
 Interferon (alpha, beta, and omega) receptor 2IFNAR21589_s_at1.8
 Interferon-stimulated transcription factor 3, gamma, 48 kDaISGF3G38517_at1.6
 Protein kinase, interferon-inducible double-stranded RNA dependentPRKR1008_f_at1.7
 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3GAPOBEC3G34947_at1.7
 V-rel reticuloendotheliosis viral oncogene homolog ARELA1271_g_at1.5
 Protein tyrosine phosphatase, receptor type, CPTPRC40520_g_at−1.6
 Interferon gamma receptor 1IFNGR11038_s_at−1.6
Cell adhesion
 Chemokine (C-C motif) ligand 4CCL436674_at16.2
 Tumor necrosis factor, alpha-induced protein 6TNFAIP61372_at14.7
 Tumor necrosis factor (TNF superfamily, member 2)TNF1852_at14.6
 Integrin, beta 8ITGB8889_at9.3
 Fasciculation and elongation protein zeta 1 (zygin I)FEZ137743_at9.1
 Secreted phosphoprotein 1SPP12092_s_at6.3
 ADAM-like, decysin 1ADAMD134974_at6.2
 Pleckstrin homology domain containing, family C (with FERM domain) member 1PLEKHC136577_at5.2
 Chemokine (C-C motif) ligand 2CCL234375_at4.1
 Intercellular adhesion molecule 1 (CD54), human rhinovirus receptorICAM132640_at4.0
 Ninjurin 1NINJ141475_at3.7
 CD44 antigen (homing function and Indian blood group system)CD441125_s_at3.0
 Laminin, beta 3LAMB336929_at2.9
 Scavenger receptor class F, member 1SCARF140034_r_at2.7
(Table continues)