Table I.

Temporal mRNA expression levels of select cytokines and chemokines in ankles of B. burgdorferi-infected micea

Day PostinfectionFold Change in mRNA Expression Levelb
  • a Tibiotarsal joints from B. burgdorferi-infected mice were collected at the times indicated and total RNA was extracted. Levels of mRNA for each cytokine or chemokine were determined using quantitative real-time PCR as described in Materials and Methods.

  • b The levels of mRNA were expressed as a fold change in the expression level of untreated normal mice (time = 0), normalized to murine Nidogen gene expression (n = 4). The experiment was conducted twice and the mean of two independent experiments is shown.