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Future Table of Contents: Volume 178 / No. 5 / Mar 1, 2007

IN THIS ISSUE

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

IN THIS ISSUE

PILLARS OF IMMUNOLOGY

Pillars Commentary: Human Tumor Immunology at the Molecular Divide

Olivera J. Finn

Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science 1991. 254: 1643-1647

Pierre van der Bruggen, Catia Traversari, Patrick Chomez, Christophe Lurquin, Etienne De Plaen, Benoit J. Van den Eynde, Alexander Knuth, and Thierry Boon

BRIEF REVIEWS

The JAK-STAT Signaling Pathway: Input and Output Integration

Peter J. Murray

CUTTING EDGE

Cutting Edge: TFII-I Controls B Cell Proliferation via Regulating NF-B

Todd Ashworth and Ananda L. Roy

Cutting Edge: Bim Is Required for Superantigen-Mediated B Cell Death

Carl S. Goodyear, Maripat Corr, Fujimi Sugiyama, David L. Boyle, and Gregg J. Silverman

Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations

Andreas Kuglstatter, Armando G. Villasenor, David Shaw, Simon W. Lee, Stan Tsing, Linghao Niu, Kyung W. Song, Jim W. Barnett, and Michelle F. Browner

Cutting Edge: IFN--Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis

Ian Justin Glomski, Jean-Philippe Corre, Michele Mock, and Pierre Louis Goossens

Cutting Edge: Oseltamivir Decreases T Cell GM1 Expression and Inhibits Clearance of Respiratory Syncytial Virus: Potential Role of Endogenous Sialidase in Antiviral Immunity

Martin L. Moore, Michael H. Chi, Weisong Zhou, Kasia Goleniewska, Jamye F. O'Neal, James N. Higginbotham, and R. Stokes Peebles, Jr.

Cutting Edge: Differential Inhibition of TLR Signaling Pathways by Cell-Permeable Peptides Representing BB Loops of TLRs

Vladimir Y. Toshchakov, Matthew J. Fenton, and Stefanie N. Vogel

Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

Mischo Kursar, Markus Koch, Hans-Willi Mittrucker, Geraldine Nouailles, Kerstin Bonhagen, Thomas Kamradt, and Stefan H. E. Kaufmann

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Murine Neonatal CD4+ Cells Are Poised for Rapid Th2 Effector-Like Function

Shawn Rose, Mathias Lichtenheld, Monica R. Foote, and Becky Adkins

Apoptotic Cells Induce Tolerance by Generating Helpless CD8+ T Cells That Produce TRAIL

Thomas S. Griffith, Hirotaka Kazama, Rebecca L. VanOosten, James K. Earle, Jr., John M. Herndon, Douglas R. Green, and Thomas A. Ferguson

NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection

Monia Draghi, Achal Pashine, Bharati Sanjanwala, Ketevan Gendzekhadze, Claudia Cantoni, David Cosman, Alessandro Moretta, Nicholas M. Valiante, and Peter Parham

Immunization of Flavivirus West Nile Recombinant Envelope Domain III Protein Induced Specific Immune Response and Protection against West Nile Virus Infection

Jang-Hann J. Chu, Cern-Cher S. Chiang, and Mah-Lee Ng

Invariant NKT Cells Amplify the Innate Immune Response to Lipopolysaccharide

Niranjana A. Nagarajan and Mitchell Kronenberg

Programmed Cell Death-1:Programmed Cell Death Ligand-1 Interactions Contribute to the Functional Suppression of Virus-Specific CD8+ T Lymphocytes in the Liver

Holly Maier, Masanori Isogawa, Gordon J. Freeman, and Francis V. Chisari

Dendritic Cell Function Can Be Modulated through Cooperative Actions of TLR Ligands and Invariant NKT Cells

Ian F. Hermans, Jonathan D. Silk, Uzi Gileadi, S. Hajar Masri, Dawn Shepherd, Kathryn J. Farrand, Mariolina Salio, and Vincenzo Cerundolo

Epigenetic and Transcriptional Programs Lead to Default IFN- Production by T Cells

Liang Chen, Weifeng He, Sean T. Kim, Jian Tao, Yunfei Gao, Hongbo Chi, Andrew M. Intlekofer, Bohdan Harvey, Steven L. Reiner, Zhinan Yin, Richard A. Flavell, and Joe Craft

Virus-Specific CD8+ T Cells in the Liver: Armed and Ready to Kill

Rachael Keating, Wen Yue, John A. Rutigliano, Jenny So, Elvia Olivas, Paul G. Thomas, and Peter C. Doherty

Gag-Specific CD8+ T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression

Jonah B. Sacha, Chungwon Chung, Eva G. Rakasz, Sean P. Spencer, Anna K. Jonas, Alexander T. Bean, Wonhee Lee, Benjamin J. Burwitz, Jason J. Stephany, John T. Loffredo, David B. Allison, Sama Adnan, Akihiko Hoji, Nancy A. Wilson, Thomas C. Friedrich, Jeffrey D. Lifson, Otto O. Yang, and David I. Watkins

Efficient Activation of V14 Invariant NKT Cells by Foreign Lipid Antigen Is Associated with Concurrent Dendritic Cell-Specific Self Recognition

Lu Cheng, Aito Ueno, Suzanne Cho, Jin S. Im, Susanne Golby, Sheng Hou, Steven A. Porcelli, and Yang Yang

Dendritic Cells Infiltrating Human Non-Small Cell Lung Cancer Are Blocked at Immature Stage

Ivan Perrot, Dominique Blanchard, Nathalie Freymond, Sylvie Isaac, Benoit Guibert, Yves Pacheco, and Serge Lebecque

Fetal Immune Responses to Plasmodium falciparum Antigens in a Malaria-Endemic Region of Cameroon

Simon Metenou, Amorsolo L. Suguitan, Jr., Carole Long, Rose G. F. Leke, and Diane Wallace Taylor

CD4+CD25+ T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes

Jovanna Gonzalez, Esther Tamayo, Ines Santiuste, Regina Marquina, Luis Buelta, Miguel A. Gonzalez-Gay, Shozo Izui, Marcos Lopez-Hoyos, Jesus Merino, and Ramon Merino

Lack of Effective MUC1 Tumor Antigen-Specific Immunity in MUC1-Transgenic Mice Results from a Th/T Regulatory Cell Imbalance That Can Be Corrected by Adoptive Transfer of Wild-Type Th Cells

Michael S. Turner, Patrice A. Cohen, and Olivera J. Finn

Effect of Both Ultraviolet B Irradiation and Histamine Receptor Function on Allergic Responses to an Inhaled Antigen

Jacqueline P. McGlade, Shelley Gorman, Jason C. Lenzo, Jamie W. Tan, Takeshi Watanabe, John J. Finlay-Jones, Wayne R. Thomas, and Prue H. Hart

Staphylococcus aureus Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 Ligands

Isabelle Bekeredjian-Ding, Seiichi Inamura, Thomas Giese, Hermann Moll, Stefan Endres, Andreas Sing, Ulrich Zahringer, and Gunther Hartmann

Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF- Involves Activation of the MKK6/p38MAPK/MK2 Cascade

Christian Ehlting, Wi S. Lai, Fred Schaper, Erwin D. Brenndorfer, Raphaela-Jessica Matthes, Peter C. Heinrich, Stephan Ludwig, Perry J. Blackshear, Matthias Gaestel, Dieter Haussinger, and Johannes G. Bode

IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production

Jonathan M. Coquet, Konstantinos Kyparissoudis, Daniel G. Pellicci, Gurdyal Besra, Stuart P. Berzins, Mark J. Smyth, and Dale I. Godfrey

IL-2/Neuroantigen Fusion Proteins as Antigen-Specific Tolerogens in Experimental Autoimmune Encephalomyelitis (EAE): Correlation of T Cell-Mediated Antigen Presentation and Tolerance Induction

Mark D. Mannie, Barbara A. Clayson, Elizabeth J. Buskirk, Jarret L. DeVine, Jose J. Hernandez, and Derek J. Abbott

CD40-CD40 Ligand Interaction between Dendritic Cells and CD8+ T Cells Is Needed to Stimulate Maximal T Cell Responses in the Absence of CD4+ T Cell Help

Maria Genevive H. Hernandez, Lianjun Shen, and Kenneth L. Rock

Tumor Cells Loaded with -Galactosylceramide Induce Innate NKT and NK Cell-Dependent Resistance to Tumor Implantation in Mice

Kanako Shimizu, Akira Goto, Mikiko Fukui, Masaru Taniguchi, and Shin-ichiro Fujii

Involvement of Src and Syk Tyrosine Kinases in HIV-1 Transfer from Dendritic Cells to CD4+ T Lymphocytes

Caroline Gilbert, Corinne Barat, Rejean Cantin, and Michel J. Tremblay

IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells

Rachel Ettinger, Gary P. Sims, Rachel Robbins, David Withers, Randy T. Fischer, Amrie C. Grammer, Stefan Kuchen, and Peter E. Lipsky

Tumor Evasion of the Immune System by Converting CD4+CD25- T Cells into CD4+CD25+ T Regulatory Cells: Role of Tumor-Derived TGF-

Victoria C. Liu, Larry Y. Wong, Thomas Jang, Ali H. Shah, Irwin Park, Ximing Yang, Qiang Zhang, Scott Lonning, Beverly A. Teicher, and Chung Lee

Induced SHIP Deficiency Expands Myeloid Regulatory Cells and Abrogates Graft-versus-Host Disease

Kim H. T. Paraiso, Tomar Ghansah, Amy Costello, Robert W. Engelman, and William G. Kerr

Augmentation of Signaling through BCR Containing IgE But not that Containing IgA Due to Lack of CD22-Mediated Signal Regulation

Motohiko Sato, Takahiro Adachi, and Takeshi Tsubata

Modulation of CD103 Expression on Human Colon Carcinoma-Specific CTL

Khoon-Lin Ling, Nicolas Dulphy, Pru Bahl, Mariolina Salio, Kevin Maskell, Juan Piris, Bryan F. Warren, Bruce D. George, Neil J. Mortensen, and Vincenzo Cerundolo

Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice

Helen Ferry, Paul K. Potter, Tanya L. Crockford, Anastasia Nijnik, Michael R. Ehrenstein, Mark J. Walport, Marina Botto, and Richard J. Cornall

Mcl-1 Depletion in Apoptosis Elicited by Ionizing Radiation in Peritoneal Resident Macrophages of C3H Mice

Yoshihisa Kubota, Keiji Kinoshita, Katsutoshi Suetomi, Akira Fujimori, and Sentaro Takahashi

CD4+ and CD8+ T Cell Survival Is Regulated Differentially by Protein Kinase C, c-Rel, and Protein Kinase B

Samuel D. Saibil, Russell G. Jones, Elissa K. Deenick, Nicole Liadis, Alisha R. Elford, Mitchell G. Vainberg, Heather Baerg, James R. Woodgett, Steve Gerondakis, and Pamela S. Ohashi

Peroxisome Proliferator-Activated Receptor Is Required for Regulatory CD4+ T Cell-Mediated Protection against Colitis

Raquel Hontecillas and Josep Bassaganya-Riera

Fitness of Cell-Mediated Immunity Independent of Repertoire Diversity

Mouhammed AbuAttieh, Michelle Rebrovich, Peter J. Wettstein, Zvezdana Vuk-Pavlovic, Andrew H. Limper, Jeffrey L. Platt, and Marilia Cascalho

Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen

Dipica Haribhai, Wen Lin, Lance M. Relland, Nga Truong, Calvin B. Williams, and Talal A. Chatila

CC Chemokine Receptor 7 Contributes to Gi-Dependent T Cell Motility in the Lymph Node

Takaharu Okada and Jason G. Cyster

Targeting of Antigen to Dendritic Cells with Poly(-Glutamic Acid) Nanoparticles Induces Antigen-Specific Humoral and Cellular Immunity

Tomofumi Uto, Xin Wang, Katsuaki Sato, Misako Haraguchi, Takami Akagi, Mitsuru Akashi, and Masanori Baba

Requirement for a Complex of Wiskott-Aldrich Syndrome Protein (WASP) with WASP Interacting Protein in Podosome Formation in Macrophages

Shigeru Tsuboi

Anti-Nuclear Antibody Production and Autoimmunity in Transgenic Mice that Overexpress the Transcription Factor Bright

Malini Shankar, Jamee C. Nixon, Shannon Maier, Jennifer Workman, A. Darise Farris, and Carol F. Webb

Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation

Geoffrey O. Gillard, James Dooley, Matthew Erickson, Leena Peltonen-Palotie, and Andrew G. Farr

MOLECULAR AND STRUCTURAL IMMUNOLOGY

Conformational Changes in Mannan-Binding Lectin Bound to Ligand Surfaces

Mingdong Dong, Sailong Xu, Cristiano L. P. Oliveira, Jan S. Pedersen, Steffen Thiel, Flemming Besenbacher, and Thomas Vorup-Jensen

Genomic Organization of the Chicken CD8 Locus Reveals a Novel Family of Immunoreceptor Genes

Hung-Jiun Liaw, Wei-Ru Chen, Yu-Chia Huang, Chung-Wei Tsai, King-Chan Chang, and Chia-Lam Kuo

Reporter Gene Insertions Reveal a Strictly B Lymphoid-Specific Expression Pattern of Pax5 in Support of Its B Cell Identity Function

Martin Fuxa and Meinrad Busslinger

Early Growth Response Transcriptional Regulators Are Dispensable for Macrophage Differentiation

John H. Carter and Warren G. Tourtellotte

Transmembrane Mutations to FcRIIA Alter Its Association with Lipid Rafts: Implications for Receptor Signaling

Erick Garcia-Garcia, Eric J. Brown, and Carlos Rosales

17-Estradiol Induces IL-1 Gene Expression in Rheumatoid Fibroblast-Like Synovial Cells through Estrogen Receptor (ER) and Augmentation of Transcriptional Activity of Sp1 by Dissociating Histone Deacetylase 2 from ER

Yuka Itoh, Hidetoshi Hayashi, Keiji Miyazawa, Soichi Kojima, Tohru Akahoshi, and Kikuo Onozaki

NFAT-Mediated Expression of TGF-1 in Tolerant T Cells

Naoko Nakano, Hiroyuki Hosokawa, Masako Kohyama, and Nobumichi Hozumi

IMMUNOGENETICS

HLA Transgenic Mice Provide Evidence for a Direct and Dominant Role of HLA Class II Variation in Modulating the Severity of Streptococcal Sepsis

Mohammed M. Nooh, Nagala El-Gengehi, Rita Kansal, Chella S. David, and Malak Kotb

Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci

Emma Ahlqvist, Robert Bockermann, and Rikard Holmdahl

HOST DEFENSE

Hidden Epitopes Emerge in Secondary Influenza Virus-Specific CD8+ T Cell Reponses

Paul G. Thomas, Scott A. Brown, Rachael Keating, Wen Yue, Melissa Y. Morris, Jenny So, Richard J. Webby, and Peter C. Doherty

A Novel Antibody-Dependent Cellular Cytotoxicity Mechanism Involved in Defense against Malaria Requires Costimulation of Monocytes FcRII and FcRIII

Ali Jafarshad, Morten H. Dziegiel, Rasmus Lundquist, Leif K. Nielsen, Subhash Singh, and Pierre L. Druilhe

Dectin-1 Stimulation by Candida albicans Yeast or Zymosan Triggers NFAT Activation in Macrophages and Dendritic Cells

Helen S. Goodridge, Randi M. Simmons, and David M. Underhill

Human Peptidoglycan Recognition Proteins Require Zinc to Kill Both Gram-Positive and Gram-Negative Bacteria and Are Synergistic with Antibacterial Peptides

Minhui Wang, Li-Hui Liu, Shiyong Wang, Xinna Li, Xiaofeng Lu, Dipika Gupta, and Roman Dziarski

Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria

Giuseppe Mancuso, Angelina Midiri, Carmelo Biondo, Concetta Beninati, Sebastiana Zummo, Roberta Galbo, Francesco Tomasello, Maria Gambuzza, Giancarlo Macri, Alessia Ruggeri, Tomas Leanderson, and Giuseppe Teti

Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells

Anja K. Mayer, Mario Muehmer, Jorg Mages, Katja Gueinzius, Christian Hess, Klaus Heeg, Robert Bals, Roland Lang, and Alexander H. Dalpke

The Type I IFN Response to Infection with Mycobacterium tuberculosis Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis

Sarah A. Stanley, James E. Johndrow, Paolo Manzanillo, and Jeffery S. Cox

Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN--Mediated Signaling Contributes to Innate Immune Responses in the Lung during Escherichia coli Pneumonia

Samithamby Jeyaseelan, Scott K. Young, Michael B. Fessler, Yuhong Liu, Kenneth C. Malcolm, Masahiro Yamamoto, Shizuo Akira, and G. Scott Worthen

Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and 1 Integrin-Mediated Pathway

Marie-Pierre Puissegur, Guillaume Lay, Martine Gilleron, Laure Botella, Jerome Nigou, Hedia Marrakchi, Bernard Mari, Jean-Luc Duteyrat, Yann Guerardel, Laurent Kremer, Pascal Barbry, Germain Puzo, and Frederic Altare

A Role of Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing IFN- in the Host Response to Pseudomonas aeruginosa Lung Infection in Mice

Melanie R. Power, Bo Li, Masahiro Yamamoto, Shizuo Akira, and Tong-Jun Lin

Efficient Capture of Antibody Neutralized HIV-1 by Cells Expressing DC-SIGN and Transfer to CD4+ T Lymphocytes

Thijs van Montfort, Alexey A. Nabatov, Teunis B. H. Geijtenbeek, Georgios Pollakis, and William A. Paxton

TLR9 Expression and Function Is Abolished by the Cervical Cancer-Associated Human Papillomavirus Type 16

Uzma A. Hasan, Elizabeth Bates, Fumihiko Takeshita, Alexandra Biliato, Rosita Accardi, Veronique Bouvard, Mariam Mansour, Isabelle Vincent, Lutz Gissmann, Thomas Iftner, Mario Sideri, Frank Stubenrauch, and Massimo Tommasino

INFLAMMATION

The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF-B and Hypoxia-Inducible Factor-1

Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Muller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler

Retinoid-Related Orphan Receptor Controls Immunoglobulin Production and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen

Stephen L. Tilley, Maisa Jaradat, Cliona Stapleton, Darlene Dixon, Xiaoyang Hua, Christopher J. Erikson, Joshua G. McCaskill, Kelly D. Chason, Grace Liao, Leigh Jania, Beverly H. Koller, and Anton M. Jetten

TLR4 Hyperresponsiveness via Cell Surface Expression of Heat Shock Protein gp96 Potentiates Suppressive Function of Regulatory T Cells

Jie Dai, Bei Liu, Soo Mun Ngoi, Shaoli Sun, Anthony T. Vella, and Zihai Li

Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia

Ziye Sui, Lynn F. Sniderhan, Giovanni Schifitto, Richard P. Phipps, Harris A. Gelbard, Stephen Dewhurst, and Sanjay B. Maggirwar

TCR Signaling Antagonizes Rapid IP-10-Mediated Transendothelial Migration of Effector Memory CD4+ T Cells

Thomas D. Manes, Stephen L. Shiao, Thomas J. Dengler, and Jordan S. Pober

IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells

Valerie Steenwinckel, Jamila Louahed, Ciriana Orabona, Francois Huaux, Guy Warnier, Andrew McKenzie, Dominique Lison, Roy Levitt, and Jean-Christophe Renauld

VCAM-1 Activation of Endothelial Cell Protein Tyrosine Phosphatase 1B

Tracy L. Deem, Hiam Abdala-Valencia, and Joan M. Cook-Mills

CLINICAL IMMUNOLOGY

Rate of Increase in Circulating IL-7 and Loss of IL-7R Expression Differ in HIV-1 and HIV-2 Infections: Two Lymphopenic Diseases with Similar Hyperimmune Activation but Distinct Outcomes

Adriana S. Albuquerque, Catarina S. Cortesao, Russell B. Foxall, Rui S. Soares, Rui M. M. Victorino, and Ana E. Sousa

Immunotherapy of Tumors with Neuroimmune Ligand Capsaicin

Jacqueline Beltran, Amiya K. Ghosh, and Sreyashi Basu

HIV-Specific IL-10-Positive CD8+ T Cells Suppress Cytolysis and IL-2 Production by CD8+ T Cells

Mohamed Elrefaei, Florence L. Ventura, Chris A. R. Baker, Richard Clark, David R. Bangsberg, and Huyen Cao

CoStimulation Blockade Inhibits Allergic Sensitization but Does Not Affect Established Allergy in a Murine Model of Grass Pollen Allergy

Birgit Linhart, Sinda Bigenzahn, Arnulf Hartl, Christian Lupinek, Josef Thalhamer, Rudolf Valenta, and Thomas Wekerle

Expression Profile of FcRIIb on Leukocytes and its Dysregulation in Systemic Lupus Erythematosus

Kaihong Su, Hengxuan Yang, Xinrui Li, Xiaoli Li, Andrew W. Gibson, John M. Cafardi, Tong Zhou, Jeffrey C. Edberg, and Robert P. Kimberly

Aberrant Expression of the Insulin-Like Growth Factor-1 Receptor by T Cells from Patients with Graves' Disease May Carry Functional Consequences for Disease Pathogenesis

Raymond S. Douglas, Andrew G. Gianoukakis, Shweta Kamat, and Terry J. Smith

Involvement of C-C Chemokine Ligand 2-CCR2 Interaction in Monocyte-Lineage Cell Recruitment of Normal Human Corneal Stroma

Nobuyuki Ebihara, Satoru Yamagami, Seiichi Yokoo, Shiro Amano, and Akira Murakami

Phenotype and Effector Function of CC Chemokine Receptor 9-Expressing Lymphocytes in Small Intestinal Crohn's Disease

Masayuki Saruta, Qi T. Yu, Armine Avanesyan, Phillip R. Fleshner, Stephan R. Targan, and Konstantinos A. Papadakis

Enhanced Antitumor Responses Elicited by Combinatorial Protein Transfer of Chemotactic and Costimulatory Molecules

Shanrong Liu, Deborah R. Breiter, Guoxing Zheng, and Aoshuang Chen

Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis

Maud Condomines, Dirk Hose, Pierre Raynaud, Michael Hundemer, John De Vos, Marion Baudard, Thomas Moehler, Veronique Pantesco, Marion Moos, Jean-Francois Schved, Jean-Francois Rossi, Thierry Reme, Hartmut Goldschmidt, and Bernard Klein

A Critical Role for Allograft Inflammatory Factor-1 in the Pathogenesis of Rheumatoid Arthritis

Mizuho Kimura, Yutaka Kawahito, Hiroshi Obayashi, Mitsuhiro Ohta, Hirokazu Hara, Tetsuo Adachi, Daisaku Tokunaga, Tatsuya Hojo, Masahide Hamaguchi, Atsushi Omoto, Hidetaka Ishino, Makoto Wada, Masataka Kohno, Yasunori Tsubouchi, and Toshikazu Yoshikawa

C3d Binding to the Myelin Oligodendrocyte Glycoprotein Results in an Exacerbated Experimental Autoimmune Encephalomyelitis

Jean-Francois Jegou, Philippe Chan, Marie-Therese Schouft, Mark R. Griffiths, James W. Neal, Philippe Gasque, Hubert Vaudry, and Marc Fontaine