IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 181: 2939-2940. [Full Text] [PDF] ImmunoCast  

PILLARS OF IMMUNOLOGY:

IL-4 Production by T Cells: You Need a Little to Get a Lot

Melissa A. Brown
J Immunol 2008 181: 2941-2942. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Generation of Interleukin 4 (IL-4)-producing Cells In Vivo and In Vitro: IL-2 and IL-4 Are Required For In Vitro Generation of IL-4-producing Cells. J. Exp. Med. 172: 921–929.

Graham Le Gros, Shlomo Z. Ben-Sasson, Robert Seder, Fred D. Finkelman, and William E. Paul
J Immunol 2008 181: 2943-2951. [PDF]  

BRIEF REVIEWS:

Comparative Functional Evolution of Human and Mouse CR1 and CR2

Amanda C. Jacobson and John H. Weis
J Immunol 2008 181: 2953-2959. [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

B Cell Depletion with Anti-CD79 mAbs Ameliorates Autoimmune Disease in MRL/lpr Mice

Yongmei Li, Fangqi Chen, Mary Putt, Yumee K. Koo, Michael Madaio, John C. Cambier, Philip L. Cohen, and Robert A. Eisenberg
J Immunol 2008 181: 2961-2972. [Abstract] [Full Text] [PDF]  

B and T Lymphocyte Attenuator Regulates T Cell Survival in the Lung

Christine Deppong, Jessica M. Degnan, Theresa L. Murphy, Kenneth M. Murphy, and Jonathan M. Green
J Immunol 2008 181: 2973-2979. [Abstract] [Full Text] [PDF]  

FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase

Stéphanie Fabre, Florent Carrette, Jing Chen, Valérie Lang, Monique Semichon, Christine Denoyelle, Vladimir Lazar, Nicolas Cagnard, Anne Dubart-Kupperschmitt, Marianne Mangeney, David A. Fruman, and Georges Bismuth
J Immunol 2008 181: 2980-2989. [Abstract] [Full Text] [PDF]  

Targeting CpG Oligonucleotides to the Lymph Node by Nanoparticles Elicits Efficient Antitumoral Immunity

Carole Bourquin, David Anz, Klaus Zwiorek, Anna-Lisa Lanz, Sebastian Fuchs, Sarah Weigel, Cornelia Wurzenberger, Philip von der Borch, Michaela Golic, Stefan Moder, Gerhard Winter, Conrad Coester, and Stefan Endres
J Immunol 2008 181: 2990-2998. [Abstract] [Full Text] [PDF]  

Induction of CD83⁺CD14⁺ Nondendritic Antigen-Presenting Cells by Exposure of Monocytes to IFN-

Gianni Gerlini, Giulia Mariotti, Alberto Chiarugi, Paola Di Gennaro, Roberto Caporale, Astrid Parenti, Leonardo Cavone, Adrian Tun-Kyi, Francesca Prignano, Riccardo Saccardi, Lorenzo Borgognoni, and Nicola Pimpinelli
J Immunol 2008 181: 2999-3008. [Abstract] [Full Text] [PDF]  

Critical and Differential Roles of NKp46- and NKp30-Activating Receptors Expressed by Uterine NK Cells in Early Pregnancy

Hicham El Costa, Audrey Casemayou, Maryse Aguerre-Girr, Magali Rabot, Alain Berrebi, Olivier Parant, Muriel Clouet-Delannoy, Letizia Lombardelli, Nabila Jabrane-Ferrat, Daniel Rukavina, Armand Bensussan, Marie-Pierre Piccinni, Philippe Le Bouteiller, and Julie Tabiasco
J Immunol 2008 181: 3009-3017. [Abstract] [Full Text] [PDF]  

Apoptotic Cell-Mediated Immunoregulation of Dendritic Cells Does Not Require iC3b Opsonization

Edward M. Behrens, Yue Ning, Nidal Muvarak, Philip W. Zoltick, Alan W. Flake, and Stefania Gallucci
J Immunol 2008 181: 3018-3026. [Abstract] [Full Text] [PDF]  

Role of Endogenous Brain-Derived Neurotrophic Factor and Sortilin in B Cell Survival

Anne-Laure Fauchais, Fabrice Lalloué, Marie-Claude Lise, Ahmed Boumediene, Jean-Louis Preud'homme, Elisabeth Vidal, and Marie-Odile Jauberteau
J Immunol 2008 181: 3027-3038. [Abstract] [Full Text] [PDF]  

Immunodominance of CD4 T Cells to Foreign Antigens Is Peptide Intrinsic and Independent of Molecular Context: Implications for Vaccine Design

Jason M. Weaver, Christopher A. Lazarski, Katherine A. Richards, Francisco A. Chaves, Scott A. Jenks, Paula R. Menges, and Andrea J. Sant
J Immunol 2008 181: 3039-3048. [Abstract] [Full Text] [PDF]  

TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol

Xue-Jun Zhao, Qing Dong, Julie Bindas, Jon D. Piganelli, Amy Magill, Jakob Reiser, and Jay K. Kolls
J Immunol 2008 181: 3049-3056. [Abstract] [Full Text] [PDF]  

Cannabinoids Affect Dendritic Cell (DC) Potassium Channel Function and Modulate DC T Cell Stimulatory Capacity

Paul W. Wacnik, Katarina M. Luhr, Russell H. Hill, Hans-Gustaf Ljunggren, Krister Kristensson, and Mattias Svensson
J Immunol 2008 181: 3057-3066. [Abstract] [Full Text] [PDF]  

Antigen Persistence Is Required for Dendritic Cell Licensing and CD8⁺ T Cell Cross-Priming

Hélène Jusforgues-Saklani, Martin Uhl, Nathalie Blachère, Fabrice Lemaître, Olivier Lantz, Philippe Bousso, Deborah Braun, James J. Moon, and Matthew L. Albert
J Immunol 2008 181: 3067-3076. [Abstract] [Full Text] [PDF]  

A Critical Role for the Proapoptotic Protein Bid in Ultraviolet-Induced Immune Suppression and Cutaneous Apoptosis

Sanjay Pradhan, Hee Kyung Kim, Christopher J. Thrash, Maureen A. Cox, Sudheer K. Mantena, Jian-He Wu, Mohammad Athar, Santosh K. Katiyar, Craig A. Elmets, and Laura Timares
J Immunol 2008 181: 3077-3088. [Abstract] [Full Text] [PDF]  

Tumor-Educated Tolerogenic Dendritic Cells Induce CD3 Down-Regulation and Apoptosis of T Cells through Oxygen-Dependent Pathways

Dong-Ming Kuang, Qiyi Zhao, Jing Xu, Jing-Ping Yun, Changyou Wu, and Limin Zheng
J Immunol 2008 181: 3089-3098. [Abstract] [Full Text] [PDF]  

Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells

Satoko Matsumura, Baomei Wang, Noriko Kawashima, Steve Braunstein, Michelle Badura, Thomas O. Cameron, James S. Babb, Robert J. Schneider, Silvia C. Formenti, Michael L. Dustin, and Sandra Demaria
J Immunol 2008 181: 3099-3107. [Abstract] [Full Text] [PDF]  

OK432-Activated Human Dendritic Cells Kill Tumor Cells via CD40/CD40 Ligand Interactions

Katy S. Hill, Fiona Errington, Lynette P. Steele, Alison Merrick, Ruth Morgan, Peter J. Selby, Nikolaos T. Georgopoulos, Dearbhaile M. O'Donnell, and Alan A. Melcher
J Immunol 2008 181: 3108-3115. [Abstract] [Full Text] [PDF]  

MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma

Teresa L. Tinder, Durai B. Subramani, Gargi D. Basu, Judy M. Bradley, Jorge Schettini, Arefayene Million, Todd Skaar, and Pinku Mukherjee
J Immunol 2008 181: 3116-3125. [Abstract] [Full Text] [PDF]  

Sodium-Dependent Glucose Transporter-1 as a Novel Immunological Player in the Intestinal Mucosa

Marco Palazzo, Silvia Gariboldi, Laura Zanobbio, Silvia Selleri, Giuseppina F. Dusio, Valentina Mauro, Anna Rossini, Andrea Balsari, and Cristiano Rumio
J Immunol 2008 181: 3126-3136. [Abstract] [Full Text] [PDF]  

Reprogrammed FoxP3⁺ T Regulatory Cells Become IL-17⁺ Antigen-Specific Autoimmune Effectors In Vitro and In Vivo

Suresh Radhakrishnan, Rosalyn Cabrera, Erin L. Schenk, Pilar Nava-Parada, Michael P. Bell, Virginia P. Van Keulen, Ronald J. Marler, Sara J. Felts, and Larry R. Pease
J Immunol 2008 181: 3137-3147. [Abstract] [Full Text] [PDF]  

The C-Type Lectin Macrophage Galactose-Type Lectin Impedes Migration of Immature APCs

Sandra J. van Vliet, Lutz C. Paessens, Venice C. M. Broks-van den Berg, Teunis B. H. Geijtenbeek, and Yvette van Kooyk
J Immunol 2008 181: 3148-3155. [Abstract] [Full Text] [PDF]  

Mononuclear Phagocyte-Derived IL-10 Suppresses the Innate IL-12/IFN- Axis in Lung-Challenged Aged Mice

Bo-Chin Chiu, Valerie R. Stolberg, and Stephen W. Chensue
J Immunol 2008 181: 3156-3166. [Abstract] [Full Text] [PDF]  

Expression and Functional Significance of SOCS-1 and SOCS-3 in Astrocytes

Hongwei Qin, Sandrine A. Niyongere, Sun Jung Lee, Brandi J. Baker, and Etty N. Benveniste
J Immunol 2008 181: 3167-3176. [Abstract] [Full Text] [PDF]  

KLRE/I1 and KLRE/I2: A Novel Pair of Heterodimeric Receptors That Inversely Regulate NK Cell Cytotoxicity

Per C. Saether, Ingunn H. Westgaard, Sigurd E. Hoelsbrekken, Jonathan Benjamin, Lewis L. Lanier, Sigbjørn Fossum, and Erik Dissen
J Immunol 2008 181: 3177-3182. [Abstract] [Full Text] [PDF]  

Human Anti-IgG1 Hinge Autoantibodies Reconstitute the Effector Functions of Proteolytically Inactivated IgGs

Randall J. Brezski, Jennifer L. Luongo, Diane Petrone, Mary H. Ryan, Degang Zhong, Susan H. Tam, Albert P. Schmidt, Marian Kruszynski, Brian P. Whitaker, David M. Knight, and Robert E. Jordan
J Immunol 2008 181: 3183-3192. [Abstract] [Full Text] [PDF]  

OX40/OX40L Costimulation Affects Induction of Foxp3⁺ Regulatory T Cells in Part by Expanding Memory T Cells In Vivo

Xiang Xiao, Alexander Kroemer, Wenda Gao, Naoto Ishii, Gulcin Demirci, and Xian Chang Li
J Immunol 2008 181: 3193-3201. [Abstract] [Full Text] [PDF]  

Myelin-Reactive Type B T Cells and T Cells Specific for Low-Affinity MHC-Binding Myelin Peptides Escape Tolerance in HLA-DR Transgenic Mice

Kazuyuki Kawamura, Katherine A. McLaughlin, Robert Weissert, and Thomas G. Forsthuber
J Immunol 2008 181: 3202-3211. [Abstract] [Full Text] [PDF]  

The Relative Efficiency of Acquisition of MHC:Peptide Complexes and Cross-Presentation Depends on Dendritic Cell Type

Lesley Ann Smyth, Nicola Harker, Wayne Turnbull, Haytham El-Doueik, Linda Klavinskis, Dimitris Kioussis, Giovanna Lombardi, and Robert Lechler
J Immunol 2008 181: 3212-3220. [Abstract] [Full Text] [PDF]  

Anergy in Memory CD4⁺ T Cells Is Induced by B Cells

Sarat K. Dalai, Saied Mirshahidi, Alexandre Morrot, Fidel Zavala, and Scheherazade Sadegh-Nasseri
J Immunol 2008 181: 3221-3231. [Abstract] [Full Text] [PDF]  

A Unique Role for the 5 Nonimmunoglobulin Tail in Early B Lymphocyte Development

Christian Vettermann, Kai Herrmann, Christine Albert, Edith Roth, Michael R. Bösl, and Hans-Martin Jäck
J Immunol 2008 181: 3232-3242. [Abstract] [Full Text] [PDF]  

The Suppression of Murine Lupus by a Tolerogenic Peptide Involves Foxp3-Expressing CD8 Cells That Are Required for the Optimal Induction and Function of Foxp3-Expressing CD4 Cells

Amir Sharabi and Edna Mozes
J Immunol 2008 181: 3243-3251. [Abstract] [Full Text] [PDF]  

Synoviocyte Innate Immune Responses: I. Differential Regulation of Interferon Responses and the JNK Pathway by MAPK Kinases

Toshio Yoshizawa, Deepa Hammaker, Susan E. Sweeney, David L. Boyle, and Gary S. Firestein
J Immunol 2008 181: 3252-3258. [Abstract] [Full Text] [PDF]  

Colocalization of Antigen-Specific B and T Cells within Ectopic Lymphoid Tissue following Immunization with Exogenous Antigen

Jason S. Weinstein, Dina C. Nacionales, Pui Y. Lee, Kindra M. Kelly-Scumpia, Xiao-Jie Yan, Philip O. Scumpia, Dustin S. Vale-Cruz, Eric Sobel, Minoru Satoh, Nicholas Chiorazzi, and Westley H. Reeves
J Immunol 2008 181: 3259-3267. [Abstract] [Full Text] [PDF]  

Human Invariant NKT Cells Display Alloreactivity Instructed by Invariant TCR-CD1d Interaction and Killer Ig Receptors

Scott Patterson, Aristeidis Chaidos, David C. A. Neville, Alessandro Poggi, Terry D. Butters, Irene A. G. Roberts, and Anastasios Karadimitris
J Immunol 2008 181: 3268-3276. [Abstract] [Full Text] [PDF]  

Apoptotic Cells Induce Immunosuppression through Dendritic Cells: Critical Roles of IFN- and Nitric Oxide

Guangwen Ren, Juanjuan Su, Xin Zhao, Liying Zhang, Jimin Zhang, Arthur I. Roberts, Huatang Zhang, Gobardhan Das, and Yufang Shi
J Immunol 2008 181: 3277-3284. [Abstract] [Full Text] [PDF]  

IL-2, -7, and -15, but Not Thymic Stromal Lymphopoeitin, Redundantly Govern CD4⁺Foxp3⁺ Regulatory T Cell Development

Kieng B. Vang, Jianying Yang, Shawn A. Mahmud, Matthew A. Burchill, Amanda L. Vegoe, and Michael A. Farrar
J Immunol 2008 181: 3285-3290. [Abstract] [Full Text] [PDF]  

Tumor-Induced CD11b⁺Gr-1⁺ Myeloid Cells Suppress T Cell Sensitization in Tumor-Draining Lymph Nodes

Satoshi Watanabe, Katsuya Deguchi, Rongxiu Zheng, Hidemasa Tamai, Li-xin Wang, Peter A. Cohen, and Suyu Shu
J Immunol 2008 181: 3291-3300. [Abstract] [Full Text] [PDF]  

Synthetic Peptide Dendrimers Block the Development and Expression of Experimental Allergic Encephalomyelitis

Keith W. Wegmann, Cynthia R. Wagner, Ruth H. Whitham, and David J. Hinrichs
J Immunol 2008 181: 3301-3309. [Abstract] [Full Text] [PDF]  

Two Macrophage Colony-Stimulating Factor Genes Exist in Fish That Differ in Gene Organization and Are Differentially Expressed

Tiehui Wang, Patrick C. Hanington, Miodrag Belosevic, and Christopher J. Secombes
J Immunol 2008 181: 3310-3322. [Abstract] [Full Text] [PDF]  

In Vivo Suppression of Naive CD4 T Cell Responses by IL-2- and Antigen-Stimulated T Lymphocytes in the Absence of APC Competition

Hiroto Inaba, Meredith Steeves, Phuong Nguyen, and Terrence L. Geiger
J Immunol 2008 181: 3323-3335. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

A Polypyrimidine Tract-Binding Protein-Dependent Pathway of mRNA Stability Initiates with CpG Activation of Primary B Cells

Joseph F. Porter, Stefano Vavassori, and Lori R. Covey
J Immunol 2008 181: 3336-3345. [Abstract] [Full Text] [PDF]  

Transcription Factor-Dependent Chromatin Remodeling of Il18r1 during Th1 and Th2 Differentiation

Qing Yu, Hua-Chen Chang, Ayele-Nati N. Ahyi, and Mark H. Kaplan
J Immunol 2008 181: 3346-3352. [Abstract] [Full Text] [PDF]  

Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA1

Clive S. McKimmie, Alasdair R. Fraser, Chris Hansell, Laura Gutiérrez, Sjaak Philipsen, Laura Connell, Antal Rot, Mariola Kurowska-Stolarska, Paz Carreno, Monika Pruenster, Chung-Ching Chu, Giovanna Lombardi, Christina Halsey, Iain B. McInnes, Foo Y. Liew, Robert J. Nibbs, and Gerard J. Graham
J Immunol 2008 181: 3353-3363. [Abstract] [Full Text] [PDF]  

EBF1 Is Essential for B-Lineage Priming and Establishment of a Transcription Factor Network in Common Lymphoid Progenitors

Sasan Zandi, Robert Mansson, Panagiotis Tsapogas, Jenny Zetterblad, David Bryder, and Mikael Sigvardsson
J Immunol 2008 181: 3364-3372. [Abstract] [Full Text] [PDF]  

Rap1b Regulates B Cell Development, Homing, and T Cell-Dependent Humoral Immunity

Haiyan Chu, Aradhana Awasthi, Gilbert C. White, II, Magdalena Chrzanowska-Wodnicka, and Subramaniam Malarkannan
J Immunol 2008 181: 3373-3383. [Abstract] [Full Text] [PDF]  

Molecular Requirements for MHC Class II -Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C

Katherine J. Kasper, Wang Xi, A. K. M. Nur-ur Rahman, Mohammed M. Nooh, Malak Kotb, Eric J. Sundberg, Joaquín Madrenas, and John K. McCormick
J Immunol 2008 181: 3384-3392. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Contribution of Mutation, Recombination, and Gene Conversion to Chicken Mhc-B Haplotype Diversity

Kazuyoshi Hosomichi, Marcia M. Miller, Ronald M. Goto, Yujun Wang, Shingo Suzuki, Jerzy K. Kulski, Masahide Nishibori, Hidetoshi Inoko, Kei Hanzawa, and Takashi Shiina
J Immunol 2008 181: 3393-3399. [Abstract] [Full Text] [PDF] Data Supplement  

Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp4

Julie M. Fletcher, Margaret A. Jordan, Sarah L. Snelgrove, Robyn M. Slattery, François D. Dufour, Konstantinos Kyparissoudis, Gurdyal S. Besra, Dale I. Godfrey, and Alan G. Baxter
J Immunol 2008 181: 3400-3412. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

The Major Bactericidal Activity of Human Seminal Plasma Is Zinc-Dependent and Derived from Fragmentation of the Semenogelins

Anneli M. L. Edström, Johan Malm, Birgitta Frohm, Julie A. Martellini, Aleksander Giwercman, Matthias Mörgelin, Alexander M. Cole, and Ole E. Sørensen
J Immunol 2008 181: 3413-3421. [Abstract] [Full Text] [PDF]  

Combined Triggering of Dendritic Cell Receptors Results in Synergistic Activation and Potent Cytotoxic Immunity

James W. Wells, Christopher J. Cowled, Farzin Farzaneh, and Alistair Noble
J Immunol 2008 181: 3422-3431. [Abstract] [Full Text] [PDF]  

B Lymphocyte Activation by Coinfection Prevents Immune Control of Friend Virus Infection

Rute Marques, Inês Antunes, Urszula Eksmond, Jonathan Stoye, Kim Hasenkrug, and George Kassiotis
J Immunol 2008 181: 3432-3440. [Abstract] [Full Text] [PDF]  

Enhanced Resistance of Restraint-Stressed Mice to Sepsis

Yu Wang, Ying Lu, Duo Yu, Yongqiang Wang, Fuyong Chen, Hanchun Yang, and Shijun J. Zheng
J Immunol 2008 181: 3441-3448. [Abstract] [Full Text] [PDF]  

Adoptive Transfer of Gene-Modified Primary NK Cells Can Specifically Inhibit Tumor Progression In Vivo

Hollie J. Pegram, Jacob T. Jackson, Mark J. Smyth, Michael H. Kershaw, and Phillip K. Darcy
J Immunol 2008 181: 3449-3455. [Abstract] [Full Text] [PDF]  

IL-17A Produced by T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

Satoru Hamada, Masayuki Umemura, Takeru Shiono, Kensho Tanaka, Ayano Yahagi, M. Dilara Begum, Kiyotetsu Oshiro, Yuko Okamoto, Hisami Watanabe, Kazuyoshi Kawakami, Christina Roark, Willi K. Born, Rebecca O'Brien, Koichi Ikuta, Hiromichi Ishikawa, Susumu Nakae, Yoichiro Iwakura, Takao Ohta, and Goro Matsuzaki
J Immunol 2008 181: 3456-3463. [Abstract] [Full Text] [PDF]  

TLR Adaptor MyD88 Is Essential for Pathogen Control during Oral Toxoplasma gondii Infection but Not Adaptive Immunity Induced by a Vaccine Strain of the Parasite

Woraporn Sukhumavasi, Charlotte E. Egan, Amy L. Warren, Gregory A. Taylor, Barbara A. Fox, David J. Bzik, and Eric Y. Denkers
J Immunol 2008 181: 3464-3473. [Abstract] [Full Text] [PDF]  

Teleost TLR22 Recognizes RNA Duplex to Induce IFN and Protect Cells from Birnaviruses

Aya Matsuo, Hiroyuki Oshiumi, Tadayuki Tsujita, Hiroshi Mitani, Hisae Kasai, Mamoru Yoshimizu, Misako Matsumoto, and Tsukasa Seya
J Immunol 2008 181: 3474-3485. [Abstract] [Full Text] [PDF]  

Inchoate CD8⁺ T Cell Responses in Neonatal Mice Permit Influenza-Induced Persistent Pulmonary Dysfunction

Dahui You, Michael Ripple, Shrilatha Balakrishna, Dana Troxclair, Dane Sandquist, Liren Ding, Terry A. Ahlert, and Stephania A. Cormier
J Immunol 2008 181: 3486-3494. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Lipopolysaccharide Is a Direct Agonist for Platelet RNA Splicing

Pavel N. Shashkin, G. Thomas Brown, Arundhati Ghosh, Gopal K. Marathe, and Thomas M. McIntyre
J Immunol 2008 181: 3495-3502. [Abstract] [Full Text] [PDF]  

PKCβII Augments NF-B-Dependent Transcription at the CCL11 Promoter via p300/CBP-Associated Factor Recruitment and Histone H4 Acetylation

Deborah L. Clarke, Amy Sutcliffe, Karl Deacon, Dawn Bradbury, Lisa Corbett, and Alan J. Knox
J Immunol 2008 181: 3503-3514. [Abstract] [Full Text] [PDF]  

Phosphorylation of 5-Lipoxygenase at Ser⁵²³ by Protein Kinase A Determines Whether Pioglitazone and Atorvastatin Induce Proinflammatory Leukotriene B₄ or Anti-Inflammatory 15-Epi-Lipoxin A₄ Production

Yumei Ye, Yu Lin, Jose R. Perez-Polo, Barry F. Uretsky, Zaiming Ye, Brian C. Tieu, and Yochai Birnbaum
J Immunol 2008 181: 3515-3523. [Abstract] [Full Text] [PDF]  

Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway

Emilia Mira, Beatriz León, Domingo F. Barber, Sonia Jiménez-Baranda, Iñigo Goya, Luis Almonacid, Gabriel Márquez, Angel Zaballos, Carlos Martínez-A., Jens V. Stein, Carlos Ardavín, and Santos Mañes
J Immunol 2008 181: 3524-3534. [Abstract] [Full Text] [PDF]  

Splenectomy Protects against Sepsis Lethality and Reduces Serum HMGB1 Levels

Jared M. Huston, Haichao Wang, Mahendar Ochani, Kanta Ochani, Mauricio Rosas-Ballina, Margot Gallowitsch-Puerta, Mala Ashok, Lihong Yang, Kevin J. Tracey, and Huan Yang
J Immunol 2008 181: 3535-3539. [Abstract] [Full Text] [PDF]  

Mitochondrial Structural Changes and Dysfunction Are Associated with Experimental Allergic Asthma

Ulaganathan Mabalirajan, Amit Kumar Dinda, Sarvesh Kumar, Reema Roshan, Pooja Gupta, Surendra Kumar Sharma, and Balaram Ghosh
J Immunol 2008 181: 3540-3548. [Abstract] [Full Text] [PDF]  

The Induction of Inflammation by Dectin-1 In Vivo Is Dependent on Myeloid Cell Programming and the Progression of Phagocytosis

Marcela Rosas, Kate Liddiard, Matti Kimberg, Inês Faro-Trindade, Jacqueline U. McDonald, David L. Williams, Gordon D. Brown, and Philip R. Taylor
J Immunol 2008 181: 3549-3557. [Abstract] [Full Text] [PDF]  

Modulation of Lipid and Protein Mediators of Inflammation by Cytosolic Phospholipase A₂ during Experimental Sepsis

Naonori Uozumi, Yoshihiro Kita, and Takao Shimizu
J Immunol 2008 181: 3558-3566. [Abstract] [Full Text] [PDF]  

Tissue-Type Plasminogen Activator Is a Regulator of Monocyte Diapedesis through the Brain Endothelial Barrier

Arie Reijerkerk, Gijs Kooij, Susanne M. A. van der Pol, Thomas Leyen, Bert van het Hof, Pierre-Olivier Couraud, Denis Vivien, Christine D. Dijkstra, and Helga E. de Vries
J Immunol 2008 181: 3567-3574. [Abstract] [Full Text] [PDF]  

Transcriptional and Translational Regulation of TGF-β Production in Response to Apoptotic Cells

Yi Qun Xiao, Celio G. Freire-de-Lima, William P. Schiemann, Donna L. Bratton, R. William Vandivier, and Peter M. Henson
J Immunol 2008 181: 3575-3585. [Abstract] [Full Text] [PDF]  

Gp130 Signaling Promotes Development of Acute Experimental Colitis by Facilitating Early Neutrophil/Macrophage Recruitment and Activation

Leif E. Sander, Florian Obermeier, Uta Dierssen, Daniela C. Kroy, Anurag K. Singh, Ursula Seidler, Konrad L. Streetz, Holger H. Lutz, Werner Müller, Frank Tacke, and Christian Trautwein
J Immunol 2008 181: 3586-3594. [Abstract] [Full Text] [PDF]  

Myeloid-Related Proteins Rapidly Modulate Macrophage Nitric Oxide Production during Innate Immune Response

Philippe Pouliot, Isabelle Plante, Marie-Astrid Raquil, Philippe A. Tessier, and Martin Olivier
J Immunol 2008 181: 3595-3601. [Abstract] [Full Text] [PDF]  

Production of C5a by ASP, a Serine Protease Released from Aeromonas sobria

Hidetoshi Nitta, Takahisa Imamura, Yoshihiro Wada, Atsushi Irie, Hidetomo Kobayashi, Keinosuke Okamoto, and Hideo Baba
J Immunol 2008 181: 3602-3608. [Abstract] [Full Text] [PDF]  

Neutrophil Apoptosis: Selective Regulation by Different Ligands of Integrin _Mβ₂

Elzbieta Pluskota, Dmitry A. Soloviev, Dorota Szpak, Christian Weber, and Edward F. Plow
J Immunol 2008 181: 3609-3619. [Abstract] [Full Text] [PDF]  

Nucleotide Oligomerization Domains 1 and 2: Regulation of Expression and Function in Preadipocytes

Thorsten Stroh, Arvind Batra, Rainer Glauben, Inka Fedke, Ulrike Erben, Anjo Kroesen, Markus M. Heimesaat, Stefan Bereswill, Stephen Girardin, Martin Zeitz, and Britta Siegmund
J Immunol 2008 181: 3620-3627. [Abstract] [Full Text] [PDF]  

CD43 Plays Both Antiadhesive and Proadhesive Roles in Neutrophil Rolling in a Context-Dependent Manner

Masanori Matsumoto, Akiko Shigeta, Masayuki Miyasaka, and Takako Hirata
J Immunol 2008 181: 3628-3635. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Characterization of HLA Class II/Peptide-TCR Interactions of the Immunodominant T Cell Epitope in Art v 1, the Major Mugwort Pollen Allergen

Beatrice Jahn-Schmid, Philémon Sirven, Victoria Leb, Winfried F. Pickl, Gottfried F. Fischer, Gabriele Gadermaier, Matthias Egger, Christof Ebner, Fatima Ferreira, Bernard Maillére, and Barbara Bohle
J Immunol 2008 181: 3636-3642. [Abstract] [Full Text] [PDF]  

Potent Simian Immunodeficiency Virus-Specific Cellular Immune Responses in the Breast Milk of Simian Immunodeficiency Virus-Infected, Lactating Rhesus Monkeys

Sallie R. Permar, Helen H. Kang, Angela Carville, Keith G. Mansfield, Rebecca S. Gelman, Srinivas S. Rao, James B. Whitney, and Norman L. Letvin
J Immunol 2008 181: 3643-3650. [Abstract] [Full Text] [PDF]  

Protection of Murine Systemic Lupus by the Ea Transgene without Expression of I-E Heterodimers

Eduardo Martínez-Soria, Marie-Laure Santiago-Raber, Liza Ho, Thomas Moll, and Shozo Izui
J Immunol 2008 181: 3651-3657. [Abstract] [Full Text] [PDF]  

PP2A Dephosphorylates Elf-1 and Determines the Expression of CD3 and FcR in Human Systemic Lupus Erythematosus T Cells

Yuang-Taung Juang, Ying Wang, Guisen Jiang, Hai-Bin Peng, Sukran Ergin, Michelle Finnell, Abigail Magilavy, Vasileios C. Kyttaris, and George C. Tsokos
J Immunol 2008 181: 3658-3664. [Abstract] [Full Text] [PDF]  

IL-2 Producing Memory CD4⁺ T Lymphocytes Are Closely Associated with the Generation of IgG-Secreting Plasma Cells

Nicolle H. R. Litjens, Martin Huisman, Daniëlle Hijdra, Bart M. N. Lambrecht, Koert J. Stittelaar, and Michiel G. H. Betjes
J Immunol 2008 181: 3665-3673. [Abstract] [Full Text] [PDF]  

Chronic Lymphocytic Leukemia Cells Bind and Present the Erythrocyte Protein Band 3: Possible Role as Initiators of Autoimmune Hemolytic Anemia

Jeremías Galletti, Cristian Cañones, Pablo Morande, Mercedes Borge, Pablo Oppezzo, Jorge Geffner, Raimundo Bezares, Romina Gamberale, and Mirta Giordano
J Immunol 2008 181: 3674-3683. [Abstract] [Full Text] [PDF]  

Memory B Cells and Pneumococcal Antibody After Splenectomy

Heather Wasserstrom, James Bussel, Lony C.-L. Lim, and Charlotte Cunningham-Rundles
J Immunol 2008 181: 3684-3689. [Abstract] [Full Text] [PDF]  

Expression of a Soluble TGF-β Receptor by Tumor Cells Enhances Dendritic Cell/Tumor Fusion Vaccine Efficacy

Min Zhang, Bradford E. Berndt, Jian-Jun Chen, and John Y. Kao
J Immunol 2008 181: 3690-3697. [Abstract] [Full Text] [PDF]  

Inhalation of Staphylococcus aureus Enterotoxin A Induces IFN- and CD8 T Cell-Dependent Airway and Interstitial Lung Pathology in Mice

Guruprasaadh Muralimohan, Robert J. Rossi, Linda A. Guernsey, Roger S. Thrall, and Anthony T. Vella
J Immunol 2008 181: 3698-3705. [Abstract] [Full Text] [PDF]  

The Src Kinase Lck Facilitates Assembly of HIV-1 at the Plasma Membrane

Amy B. Strasner, Malini Natarajan, Tom Doman, Douglas Key, Avery August, and Andrew J. Henderson
J Immunol 2008 181: 3706-3713. [Abstract] [Full Text] [PDF]  

Increased Regulatory versus Effector T Cell Development Is Associated with Thymus Atrophy in Mouse Models of Multiple Myeloma

Ayelet Laronne-Bar-On, Dov Zipori, and Nechama Haran-Ghera
J Immunol 2008 181: 3714-3724. [Abstract] [Full Text] [PDF]  

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