IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2008 180: 6435-6436. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Comment on "Homeostasis of the Naive CD4⁺ T Cell Compartment during Aging"

Andreas Thiel and Siegfried Kohler
J Immunol 2008 180: 6437. [Full Text] [PDF]  

Response to Comment on "Homeostasis of the Naive CD4⁺ T Cell Compartment during Aging"

Ryan D. Kilpatrick, Tammy Rickabaugh, and Beth D. Jamieson
J Immunol 2008 180: 6437. [Full Text] [PDF]  

BRIEF REVIEWS:

The Physiology of Leukocyte Recruitment: An In Vivo Perspective

Björn Petri, Mia Phillipson, and Paul Kubes
J Immunol 2008 180: 6439-6446. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: MHC Class I–Ly49 Interaction Regulates Neuronal Function

Ofer Zohar, Yoram Reiter, Jack R. Bennink, Avital Lev, Sebastiano Cavallaro, Sabrina Paratore, Chaim G. Pick, Gary Brooker, and Jonathan W. Yewdell
J Immunol 2008 180: 6447-6451. [Abstract] [Full Text] [PDF]  

Cutting Edge: Nonglycosidic CD1d Lipid Ligands Activate Human and Murine Invariant NKT Cells

Jonathan D. Silk, Mariolina Salio, B. Gopal Reddy, Dawn Shepherd, Uzi Gileadi, James Brown, S. Hajar Masri, Paolo Polzella, Gerd Ritter, Gurdyal S. Besra, E. Yvonne Jones, Richard R. Schmidt, and Vincenzo Cerundolo
J Immunol 2008 180: 6452-6456. [Abstract] [Full Text] [PDF]  

Cutting Edge: Central Nervous System Plasmacytoid Dendritic Cells Regulate the Severity of Relapsing Experimental Autoimmune Encephalomyelitis

Samantha L. Bailey-Bucktrout, Sarah C. Caulkins, Gwendolyn Goings, Jens A. A. Fischer, Andrzej Dzionek, and Stephen D. Miller
J Immunol 2008 180: 6457-6461. [Abstract] [Full Text] [PDF]  

Cutting Edge: Rapid Accumulation of Epidermal CCL27 in Skin-Draining Lymph Nodes following Topical Application of a Contact Sensitizer Recruits CCR10-Expressing T Cells

Victor Huang, Anke S. Lonsdorf, Lei Fang, Takashi Kakinuma, Vivian C. Lee, Emily Cha, Hong Zhang, Keisuke Nagao, Marzanna Zaleska, Waldemar L. Olszewski, and Sam T. Hwang
J Immunol 2008 180: 6462-6466. [Abstract] [Full Text] [PDF]  

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4⁺CD25⁺FoxP3⁺ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

Xin Chen, Jeffrey J. Subleski, Heather Kopf, O. M. Zack Howard, Daniela N. Männel, and Joost J. Oppenheim
J Immunol 2008 180: 6467-6471. [Abstract] [Full Text] [PDF]  

Cutting Edge: Murine Cytomegalovirus Induces a Polyfunctional CD4 T Cell Response

Ramon Arens, Peng Wang, John Sidney, Andrea Loewendorf, Alessandro Sette, Stephen P. Schoenberger, Bjoern Peters, and Chris A. Benedict
J Immunol 2008 180: 6472-6476. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

The Critical Role of IL-15 in the Antitumor Effects Mediated by the Combination Therapy Imatinib and IL-2

Grégoire Mignot, Evelyn Ullrich, Mathieu Bonmort, Cédric Ménard, Lionel Apetoh, Julien Taieb, Daniela Bosisio, Silvano Sozzani, Maria Ferrantini, Jürg Schmitz, Matthias Mack, Bernard Ryffel, Silvia Bulfone-Paus, Laurence Zitvogel, and Nathalie Chaput
J Immunol 2008 180: 6477-6483. [Abstract] [Full Text] [PDF]  

Contribution of TCR-β Locus and HLA to the Shape of the Mature Human Vβ Repertoire

J. Joseph Melenhorst, Matthew D. H. Lay, David A. Price, Sharon D. Adams, Josette Zeilah, Edgardo Sosa, Nancy F. Hensel, Dean Follmann, Daniel C. Douek, Miles P. Davenport, and A. John Barrett
J Immunol 2008 180: 6484-6489. [Abstract] [Full Text] [PDF]  

HIV-Induced Changes in T Cell Signaling Pathways

Marc Schweneker, David Favre, Jeffrey N. Martin, Steven G. Deeks, and Joseph M. McCune
J Immunol 2008 180: 6490-6500. [Abstract] [Full Text] [PDF]  

Imprinting of CCR9 on CD4 T Cells Requires IL-4 Signaling on Mesenteric Lymph Node Dendritic Cells

Raul Elgueta, Fernando E. Sepulveda, Felipe Vilches, Leonardo Vargas, J. Rodrigo Mora, Maria Rosa Bono, and Mario Rosemblatt
J Immunol 2008 180: 6501-6507. [Abstract] [Full Text] [PDF]  

Functional Consequences of Interactions between Human NKR-P1A and Its Ligand LLT1 Expressed on Activated Dendritic Cells and B Cells

David B. Rosen, Wei Cao, Danielle T. Avery, Stuart G. Tangye, Yong-Jun Liu, J. P. Houchins, and Lewis L. Lanier
J Immunol 2008 180: 6508-6517. [Abstract] [Full Text] [PDF]  

T Cell Ig and Mucin Domain-1-Mediated T Cell Activation Requires Recruitment and Activation of Phosphoinositide 3-Kinase

Anjali J. de Souza, Jean S. Oak, Ryan Jordanhazy, Rosemarie H. DeKruyff, David A. Fruman, and Lawrence P. Kane
J Immunol 2008 180: 6518-6526. [Abstract] [Full Text] [PDF]  

Antiproliferative Activity of IL-27 on Melanoma

Takayuki Yoshimoto, Noriko Morishima, Izuru Mizoguchi, Motomu Shimizu, Hiroshi Nagai, Shuntaro Oniki, Masahiro Oka, Chikako Nishigori, and Junichiro Mizuguchi
J Immunol 2008 180: 6527-6535. [Abstract] [Full Text] [PDF]  

Long-Term Functionality of TCR-Transduced T Cells In Vivo

Miriam Coccoris, Erwin Swart, Moniek A. de Witte, Jeroen W. J. van Heijst, John B. A. G. Haanen, Koen Schepers, and Ton N. M. Schumacher
J Immunol 2008 180: 6536-6543. [Abstract] [Full Text] [PDF]  

Naive and Innate Memory Phenotype CD4⁺ T Cells Have Different Requirements for Active Itk for Their Development

Jianfang Hu and Avery August
J Immunol 2008 180: 6544-6552. [Abstract] [Full Text] [PDF]  

Activation of a TGF-β-Specific Multistep Gene Expression Program in Mature Macrophages Requires Glucocorticoid-Mediated Surface Expression of TGF-β Receptor II

Alexei Gratchev, Julia Kzhyshkowska, Sheila Kannookadan, Miriam Ochsenreiter, Anna Popova, Xiaolei Yu, Srinivas Mamidi, Eugenia Stonehouse-Usselmann, Isabelle Muller-Molinet, LiMing Gooi, and Sergij Goerdt
J Immunol 2008 180: 6553-6565. [Abstract] [Full Text] [PDF]  

Preferential Costimulation by CD80 Results in IL-10-Dependent TGF-β1⁺-Adaptive Regulatory T Cell Generation

Nicolas Perez, Subha Karumuthil-Melethil, Ruobing Li, Bellur S. Prabhakar, Mark J. Holterman, and Chenthamarakshan Vasu
J Immunol 2008 180: 6566-6576. [Abstract] [Full Text] [PDF]  

Human Cytomegalovirus Latent Infection of Myeloid Cells Directs Monocyte Migration by Up-Regulating Monocyte Chemotactic Protein-1

J. Lewis Stern and Barry Slobedman
J Immunol 2008 180: 6577-6585. [Abstract] [Full Text] [PDF]  

Stabilized β-Catenin Potentiates Fas-Mediated T Cell Apoptosis

Zhaofeng Huang, Ruiqing Wang, Huimin Xie, Weirong Shang, Santhakumar Manicassamy, and Zuoming Sun
J Immunol 2008 180: 6586-6592. [Abstract] [Full Text] [PDF]  

Long-Term Cardiac Allograft Survival across an MHC Mismatch after "Pruning" of Alloreactive CD4 T Cells

Min Hu, Debbie Watson, Geoff Y. Zhang, Nicole Graf, Yuan M. Wang, Mary Sartor, Brian Howden, Jeffrey Fletcher, and Stephen I. Alexander
J Immunol 2008 180: 6593-6603. [Abstract] [Full Text] [PDF]  

A Novel B Cell-Mediated Transport of IgE-Immune Complexes to the Follicle of the Spleen

Fredrik Hjelm, Mikael C. I. Karlsson, and Birgitta Heyman
J Immunol 2008 180: 6604-6610. [Abstract] [Full Text] [PDF]  

Administration of PLP_139–151 Primes T Cells Distinct from Those Spontaneously Responsive In Vitro to This Antigen

Romina Penitente, Chiara Nicolò, Peter Van den Elzen, Gabriele Di Sante, Chiara Agrati, Francesca Aloisi, Eli E. Sercarz, and Francesco Ria
J Immunol 2008 180: 6611-6622. [Abstract] [Full Text] [PDF]  

Cigarette Smoke Exposure Impairs Dendritic Cell Maturation and T Cell Proliferation in Thoracic Lymph Nodes of Mice

Clinton S. Robbins, Francesca Franco, Majd Mouded, Manuela Cernadas, and Steven D. Shapiro
J Immunol 2008 180: 6623-6628. [Abstract] [Full Text] [PDF]  

IL-12-Impaired and IL-12-Secreting Dendritic Cells Produce IL-23 upon CD154 Restimulation

Edith Jasny, Martin Eisenblätter, Kerstin Mätz-Rensing, Klara Tenner-Racz, Matthias Tenbusch, Annette Schrod, Christiane Stahl-Hennig, Verena Moos, Thomas Schneider, Paul Racz, Klaus Überla, Franz-Josef Kaup, and Ralf Ignatius
J Immunol 2008 180: 6629-6639. [Abstract] [Full Text] [PDF]  

Location and Time-Dependent Control of Rejection by Regulatory T Cells Culminates in a Failure to Generate Memory T Cells

Manuela Carvalho-Gaspar, Nick D. Jones, Shiqiao Luo, Laurent Martin, Matthew O. Brook, and Kathryn J. Wood
J Immunol 2008 180: 6640-6648. [Abstract] [Full Text] [PDF]  

Regulatory T Cell Expression of Herpesvirus Entry Mediator Suppresses the Function of B and T Lymphocyte Attenuator-Positive Effector T Cells

Ran Tao, Liqing Wang, Kenneth M. Murphy, Christopher C. Fraser, and Wayne W. Hancock
J Immunol 2008 180: 6649-6655. [Abstract] [Full Text] [PDF]  

Overlapping and Distinct Roles of STAT4 and T-bet in the Regulation of T Cell Differentiation and Allergic Airway Inflammation

Shunsuke Furuta, Shin-ichiro Kagami, Tomohiro Tamachi, Kei Ikeda, Michio Fujiwara, Akira Suto, Koichi Hirose, Norihiko Watanabe, Yasushi Saito, Itsuo Iwamoto, and Hiroshi Nakajima
J Immunol 2008 180: 6656-6662. [Abstract] [Full Text] [PDF]  

DNA Microarray Gene Expression Profile of Marginal Zone versus Follicular B Cells and Idiotype Positive Marginal Zone B Cells before and after Immunization with Streptococcus pneumoniae

Nicholas W. Kin, Dianna M. Crawford, Jiabin Liu, Timothy W. Behrens, and John F. Kearney
J Immunol 2008 180: 6663-6674. [Abstract] [Full Text] [PDF]  

Signaling Mechanism of HIV-1 gp120 and Virion-Induced IL-1β Release in Primary Human Macrophages

Ricky Cheung, Vipa Ravyn, Lingshu Wang, Andrzej Ptasznik, and Ronald G. Collman
J Immunol 2008 180: 6675-6684. [Abstract] [Full Text] [PDF]  

Actin-Binding Protein 1 Regulates B Cell Receptor-Mediated Antigen Processing and Presentation in Response to B Cell Receptor Activation

Olusegun O. Onabajo, Margaret K. Seeley, Amruta Kale, Britta Qualmann, Michael Kessels, Jin Han, Tse-Hua Tan, and Wenxia Song
J Immunol 2008 180: 6685-6695. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Mannan Chain Length Controls Lipoglycans Signaling via and Binding to TLR2

Jérôme Nigou, Thierry Vasselon, Aurélie Ray, Patricia Constant, Martine Gilleron, Gurdyal S. Besra, Iain Sutcliffe, Gérard Tiraby, and Germain Puzo
J Immunol 2008 180: 6696-6702. [Abstract] [Full Text] [PDF]  

Dynamics of Proximal Signaling Events after TCR/CD8-Mediated Induction of Proliferation or Apoptosis in Mature CD8⁺ T Cells

Xiaoqian Wang, Luca Simeoni, Jonathan A. Lindquist, Julio Saez-Rodriguez, Andreas Ambach, Ernst D. Gilles, Stefanie Kliche, and Burkhart Schraven
J Immunol 2008 180: 6703-6712. [Abstract] [Full Text] [PDF]  

The Chemokine Receptor CXCR3 Is Degraded following Internalization and Is Replenished at the Cell Surface by De Novo Synthesis of Receptor

Andrea Meiser, Anja Mueller, Emma L. Wise, Ellen M. McDonagh, Sarah J. Petit, Namita Saran, Peter C. Clark, Timothy J. Williams, and James E. Pease
J Immunol 2008 180: 6713-6724. [Abstract] [Full Text] [PDF]  

The Downstream Transcriptional Enhancer, Ed, Positively Regulates Mouse Ig Gene Expression and Somatic Hypermutation

Yougui Xiang and William T. Garrard
J Immunol 2008 180: 6725-6732. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

The Ewing Sarcoma Protein (EWS) Binds Directly to the Proximal Elements of the Macrophage-Specific Promoter of the CSF-1 Receptor (csf1r) Gene

David A. Hume, Tedjo Sasmono, S. Roy Himes, Sudarshana M. Sharma, Agnieszka Bronisz, Myrna Constantin, Michael C. Ostrowski, and Ian L. Ross
J Immunol 2008 180: 6733-6742. [Abstract] [Full Text] [PDF]  

Novel KIR3DL1 Alleles and Their Expression Levels on NK Cells: Convergent Evolution of KIR3DL1 Phenotype Variation?

Rasmi Thomas, Eriko Yamada, Galit Alter, Maureen P. Martin, Arman A. Bashirova, Paul J. Norman, Marcus Altfeld, Peter Parham, Stephen K. Anderson, Daniel W. McVicar, and Mary Carrington
J Immunol 2008 180: 6743-6750. [Abstract] [Full Text] [PDF]  

Common Genetic Determinants of Uveitis Shared with Other Autoimmune Disorders

Mary J. Mattapallil, Azize Sahin, Phyllis B. Silver, Shu-Hui Sun, Chi-Chao Chan, Elaine F. Remmers, J. Fielding Hejtmancik, and Rachel R. Caspi
J Immunol 2008 180: 6751-6759. [Abstract] [Full Text] [PDF] Data Supplement  

HOST DEFENSE:

Dynamics of Immune Cell Recruitment during West Nile Encephalitis and Identification of a New CD19⁺B220^–BST-2⁺ Leukocyte Population

Anne-Claire Bréhin, Juliette Mouriès, Marie-Pascale Frenkiel, Gilles Dadaglio, Philippe Desprès, Monique Lafon, and Thérèse Couderc
J Immunol 2008 180: 6760-6767. [Abstract] [Full Text] [PDF]  

Ly49H⁺ NK Cells Migrate to and Protect Splenic White Pulp Stroma from Murine Cytomegalovirus Infection

Vasileios Bekiaris, Olga Timoshenko, Tie Zheng Hou, Kai Toellner, Saba Shakib, Fabrina Gaspal, Fiona M. McConnell, Sonia M. Parnell, David Withers, Chris D. Buckley, Clive Sweet, Wayne M. Yokoyama, Graham Anderson, and Peter J. L. Lane
J Immunol 2008 180: 6768-6776. [Abstract] [Full Text] [PDF]  

Increasing the CD4⁺ T Cell Precursor Frequency Leads to Competition for IFN- Thereby Degrading Memory Cell Quantity and Quality

Jason K. Whitmire, Nicola Benning, Boreth Eam, and J. Lindsay Whitton
J Immunol 2008 180: 6777-6785. [Abstract] [Full Text] [PDF]  

Munc13-4 Regulates Granule Secretion in Human Neutrophils

Christophe Pivot-Pajot, Frederique Varoqueaux, Geneviève de Saint Basile, and Sylvain G. Bourgoin
J Immunol 2008 180: 6786-6797. [Abstract] [Full Text] [PDF]  

Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-Infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques

Jacob D. Estes, Shari N. Gordon, Ming Zeng, Ann M. Chahroudi, Richard M. Dunham, Silvija I. Staprans, Cavan S. Reilly, Guido Silvestri, and Ashley T. Haase
J Immunol 2008 180: 6798-6807. [Abstract] [Full Text] [PDF]  

NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells

Maya Vinzing, Julia Eitel, Juliane Lippmann, Andreas C. Hocke, Janine Zahlten, Hortense Slevogt, Philippe Dje N'Guessan, Stefan Günther, Bernd Schmeck, Stefan Hippenstiel, Antje Flieger, Norbert Suttorp, and Bastian Opitz
J Immunol 2008 180: 6808-6815. [Abstract] [Full Text] [PDF]  

IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens

Sara M. Dann, Martina E. Spehlmann, Dustin C. Hammond, Mitsutoshi Iimura, Koji Hase, Lillian J. Choi, Elaine Hanson, and Lars Eckmann
J Immunol 2008 180: 6816-6826. [Abstract] [Full Text] [PDF]  

CEACAM1 Dynamics during Neisseria gonorrhoeae Suppression of CD4⁺ T Lymphocyte Activation

Hannah S. W. Lee, Mario A. Ostrowski, and Scott D. Gray-Owen
J Immunol 2008 180: 6827-6835. [Abstract] [Full Text] [PDF]  

Decreased Pathology and Prolonged Survival of Human DC-SIGN Transgenic Mice during Mycobacterial Infection

Martin Schaefer, Norbert Reiling, Cornelia Fessler, Johannes Stephani, Ichiro Taniuchi, Farahnaz Hatam, Ali Oender Yildirim, Heinz Fehrenbach, Kerstin Walter, Juergen Ruland, Hermann Wagner, Stefan Ehlers, and Tim Sparwasser
J Immunol 2008 180: 6836-6845. [Abstract] [Full Text] [PDF]  

Additive Roles for MCP-1 and MCP-3 in CCR2-Mediated Recruitment of Inflammatory Monocytes during Listeria monocytogenes Infection

Ting Jia, Natalya V. Serbina, Katharina Brandl, Maggie X. Zhong, Ingrid M. Leiner, Israel F. Charo, and Eric G. Pamer
J Immunol 2008 180: 6846-6853. [Abstract] [Full Text] [PDF]  

Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Independent Resistance to Aspergillus fumigatus in Alveolar Macrophages

E. Jean Cornish, Brady J. Hurtgen, Kate McInnerney, Nancy L. Burritt, Ross M. Taylor, James N. Jarvis, Shirley Y. Wang, and James B. Burritt
J Immunol 2008 180: 6854-6867. [Abstract] [Full Text] [PDF]  

Lactoferrin Acts as an Alarmin to Promote the Recruitment and Activation of APCs and Antigen-Specific Immune Responses

Gonzalo de la Rosa, De Yang, Poonam Tewary, Atul Varadhachary, and Joost J. Oppenheim
J Immunol 2008 180: 6868-6876. [Abstract] [Full Text] [PDF]  

Coinfection with Nonlethal Murine Malaria Parasites Suppresses Pathogenesis Caused by Plasmodium berghei NK65

Mamoru Niikura, Shigeru Kamiya, Kiyoshi Kita, and Fumie Kobayashi
J Immunol 2008 180: 6877-6884. [Abstract] [Full Text] [PDF]  

Macrophage Proinflammatory Response to Francisella tularensis Live Vaccine Strain Requires Coordination of Multiple Signaling Pathways

Leah E. Cole, Araceli Santiago, Eileen Barry, Tae Jin Kang, Kari Ann Shirey, Zachary J. Roberts, Karen L. Elkins, Alan S. Cross, and Stefanie N. Vogel
J Immunol 2008 180: 6885-6891. [Abstract] [Full Text] [PDF]  

Host and Donor Immune Responses Contribute to Antiviral Effects of Amotosalen-Treated Donor Lymphocytes following Early Posttransplant Cytomegalovirus Infection

Mohammad S. Hossain, John D. Roback, Fengrong Wang, and Edmund K. Waller
J Immunol 2008 180: 6892-6902. [Abstract] [Full Text] [PDF]  

Agonists of Proteinase-Activated Receptor-2 Enhance IFN--Inducible Effects on Human Monocytes: Role in Influenza A Infection

Micha Feld, Victoria M. Shpacovitch, Christina Ehrhardt, Claus Kerkhoff, Morley D. Hollenberg, Nathalie Vergnolle, Stephan Ludwig, and Martin Steinhoff
J Immunol 2008 180: 6903-6910. [Abstract] [Full Text] [PDF]  

Dual Role of NOX2 in Respiratory Syncytial Virus- and Sendai Virus-Induced Activation of NF-B in Airway Epithelial Cells

Karin Fink, Annick Duval, Alexis Martel, Anton Soucy-Faulkner, and Nathalie Grandvaux
J Immunol 2008 180: 6911-6922. [Abstract] [Full Text] [PDF]  

Blockade of Virus Infection by Human CD4⁺ T Cells via a Cytokine Relay Network

Ann M. Davis, Kristan A. Hagan, Loderick A. Matthews, Gagan Bajwa, Michelle A. Gill, Michael Gale, Jr., and J. David Farrar
J Immunol 2008 180: 6923-6932. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Heme Oxygenase-1 Protects against Neutrophil-Mediated Intestinal Damage by Down-Regulation of Neutrophil p47^phox and p67^phox Activity and O₂^– Production in a Two-Hit Model of Alcohol Intoxication and Burn Injury

Xiaoling Li, Martin G. Schwacha, Irshad H. Chaudry, and Mashkoor A. Choudhry
J Immunol 2008 180: 6933-6940. [Abstract] [Full Text] [PDF]  

Enhanced Dendritic Cell Survival Attenuates Lipopolysaccharide-Induced Immunosuppression and Increases Resistance to Lethal Endotoxic Shock

Emmanuel L. Gautier, Thierry Huby, Flora Saint-Charles, Betty Ouzilleau, M. John Chapman, and Philippe Lesnik
J Immunol 2008 180: 6941-6946. [Abstract] [Full Text] [PDF]  

CD47 Deficiency Protects Mice from Lipopolysaccharide-Induced Acute Lung Injury and Escherichia coli Pneumonia

Xiao Su, Mette Johansen, Mark R. Looney, Eric J. Brown, and Michael A. Matthay
J Immunol 2008 180: 6947-6953. [Abstract] [Full Text] [PDF]  

Toll-Like Receptor-4 Modulates Survival by Induction of Left Ventricular Remodeling after Myocardial Infarction in Mice

Alexander Riad, Sebastian Jäger, Meike Sobirey, Felicitas Escher, Aymaru Yaulema-Riss, Dirk Westermann, Aysun Karatas, Markus M. Heimesaat, Stefan Bereswill, Duska Dragun, Matthias Pauschinger, Heinz P. Schultheiss, and Carsten Tschöpe
J Immunol 2008 180: 6954-6961. [Abstract] [Full Text] [PDF]  

Properdin Deficiency in Murine Models of Nonseptic Shock

Nina D. Ivanovska, Petya A. Dimitrova, Jeni C. Luckett, Rana El-Rachkidy Lonnen, Wilhelm J. Schwaeble, and Cordula M. Stover
J Immunol 2008 180: 6962-6969. [Abstract] [Full Text] [PDF]  

Functional Th1 Cells Are Required for Surgical Adhesion Formation in a Murine Model

Arthur O. Tzianabos, Matthew A. Holsti, Xin-Xiao Zheng, Arthur F. Stucchi, Vijay K. Kuchroo, Terry B. Strom, Laurie H. Glimcher, and William W. Cruikshank
J Immunol 2008 180: 6970-6976. [Abstract] [Full Text] [PDF]  

Development of a Novel Noncompetitive Antagonist of IL-1 Receptor

Christiane Quiniou, Przemyslaw Sapieha, Isabelle Lahaie, Xin Hou, Sonia Brault, Martin Beauchamp, Martin Leduc, Lenka Rihakova, Jean-Sébastien Joyal, Sylvain Nadeau, Nikolaus Heveker, William Lubell, Florian Sennlaub, Fernand Gobeil, Jr., Greg Miller, Alexey V. Pshezhetsky, and Sylvain Chemtob
J Immunol 2008 180: 6977-6987. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Simvastatin Inhibits IL-17 Secretion by Targeting Multiple IL-17-Regulatory Cytokines and by Inhibiting the Expression of IL-17 Transcription Factor RORC in CD4⁺ Lymphocytes

Xin Zhang, Jianping Jin, Xueyan Peng, Vinod S. Ramgolam, and Silva Markovic-Plese
J Immunol 2008 180: 6988-6996. [Abstract] [Full Text] [PDF]  

Development of Inflammatory Bowel Disease in Long-Evans Cinnamon Rats Based on CD4⁺CD25⁺Foxp3⁺ Regulatory T Cell Dysfunction

Naozumi Ishimaru, Akiko Yamada, Masayuki Kohashi, Rieko Arakaki, Tetsuyuki Takahashi, Keisuke Izumi, and Yoshio Hayashi
J Immunol 2008 180: 6997-7008. [Abstract] [Full Text] [PDF]  

Long-Term Engraftment and Expansion of Tumor-Derived Memory T Cells Following the Implantation of Non-Disrupted Pieces of Human Lung Tumor into NOD-scid IL2R^null Mice

Michelle R. Simpson-Abelson, Gregory F. Sonnenberg, Hiroshi Takita, Sandra J. Yokota, Thomas F. Conway, Jr., Raymond J. Kelleher, Jr., Leonard D. Shultz, Maurice Barcos, and Richard B. Bankert
J Immunol 2008 180: 7009-7018. [Abstract] [Full Text] [PDF]  

Enhancement of DNA Vaccine Potency through Coadministration of CIITA DNA with DNA Vaccines via Gene Gun

Daejin Kim, Talia Hoory, Archana Monie, Jenny Pan-Yun Ting, Chien-Fu Hung, and T.-C. Wu
J Immunol 2008 180: 7019-7027. [Abstract] [Full Text] [PDF]  

Antigen Sensitivity of CD22-Specific Chimeric TCR Is Modulated by Target Epitope Distance from the Cell Membrane

Scott E. James, Philip D. Greenberg, Michael C. Jensen, Yukang Lin, Jinjuan Wang, Brian G. Till, Andrew A. Raubitschek, Stephen J. Forman, and Oliver W. Press
J Immunol 2008 180: 7028-7038. [Abstract] [Full Text] [PDF]  

H2E-Derived E52-68 Peptide Presented by H2A^b Interferes with Clonal Deletion of Autoreactive T Cells in Autoimmune Thyroiditis

Nicholas K. Brown, Daniel J. McCormick, Chella S. David, and Yi-chi M. Kong
J Immunol 2008 180: 7039-7046. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Improved protection against disseminated tuberculosis by Mycobacterium bovis bacillus Calmette-Guérin secreting murine GM-CSF is associated with expansion and activation of APCs

A. A. Ryan, T. M. Wozniak, E. Shklovskaya, M. A. O'Donnell, B. Fazekas de St. Groth, W. J. Britton, and J. A. Triccas
J Immunol 2008 180: 7047. [Full Text] [PDF]  

CD4⁺ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis

A. L. Rankin, A. J. Reed, S. Oh, C. Cozzo Picca, H. M. Guay, J. Larkin, III, L. Panarey, M. K. Aitken, B. Koeberlein, P. E. Lipsky, J. E. Tomaszewski, A. Naji, and A. J. Caton
J Immunol 2008 180: 7047. [Full Text] [PDF]  

Estrogen receptor , but not β, is required for optimal dendritic cell differentiation and of CD40-induced cytokine production

V. Douin-Echinard, S. Laffont, C. Seillet, L. Delpy, A. Krust, P. Chambon, P. Gourdy, J.-F. Arnal, and J.-C. Guéry
J Immunol 2008 180: 7047. [Full Text] [PDF]  

Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration

N. Sahu, C. Mueller, A. Fischer, and A. August
J Immunol 2008 180: 7047-7048. [Full Text] [PDF]  

Immunodominance in the TCR repertoire of TCR peptide-specific CD4⁺ Treg population that controls experimental autoimmune encephalomyelitis

L. T. Madakamutil, I. Maricic, E. E. Sercarz, and V. Kumar
J Immunol 2008 180: 7048. [Full Text] [PDF]  

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