IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2007 178: 2605-2606. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Comment on "Local CD11c⁺ MHC Class II^– Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process"

Christophe von Garnier, Deborah Strickland, and Philip Stumbles
J Immunol 2007 178: 2609. [Full Text] [PDF]  

Response to Comment on "Local CD11c⁺ MHC Class II^– Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process"

Hongwei Wang and Jürgen Schwarze
J Immunol 2007 178: 2609-2610. [Full Text] [PDF]  

Comment on "Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in Staphylococcus aureus"

Sonja von Aulock, Thomas Hartung, and Corinna Hermann
J Immunol 2007 178: 2610. [Full Text] [PDF]  

Response to Comment on "Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in Staphylococcus aureus"

Masahito Hashimoto, Maiko Furuyashiki, and Yasuo Suda
J Immunol 2007 178: 2610-2611. [Full Text] [PDF]  

Comment on "Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8⁺ T Cells"

Angelika Schwanninger, Birgit Weinberger, and Beatrix Grubeck-Loebenstein
J Immunol 2007 178: 2611-2612. [Full Text] [PDF]  

Response to Comment on "Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8⁺ T Cells"

Ester M. M. van Leeuwen, René A. W. van Lier, and Ineke J. M. ten Berge
J Immunol 2007 178: 2612. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Human Tumor Immunology at the Molecular Divide

Olivera J. Finn
J Immunol 2007 178: 2615-2616. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science 1991. 254: 1643–1647.

Pierre van der Bruggen, Catia Traversari, Patrick Chomez, Christophe Lurquin, Etienne De Plaen, Benoît J. Van den Eynde, Alexander Knuth, and Thierry Boon
J Immunol 2007 178: 2617-2621. [PDF]  

BRIEF REVIEWS:

The JAK-STAT Signaling Pathway: Input and Output Integration

Peter J. Murray
J Immunol 2007 178: 2623-2629. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: TFII-I Controls B Cell Proliferation via Regulating NF-B

Todd Ashworth and Ananda L. Roy
J Immunol 2007 178: 2631-2635. [Abstract] [Full Text] [PDF]  

Cutting Edge: Bim Is Required for Superantigen-Mediated B Cell Death

Carl S. Goodyear, Maripat Corr, Fujimi Sugiyama, David L. Boyle, and Gregg J. Silverman
J Immunol 2007 178: 2636-2640. [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations

Andreas Kuglstatter, Armando G. Villaseñor, David Shaw, Simon W. Lee, Stan Tsing, Linghao Niu, Kyung W. Song, Jim W. Barnett, and Michelle F. Browner
J Immunol 2007 178: 2641-2645. [Abstract] [Full Text] [PDF]  

Cutting Edge: IFN--Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis

Ian Justin Glomski, Jean-Philippe Corre, Michèle Mock, and Pierre Louis Goossens
J Immunol 2007 178: 2646-2650. [Abstract] [Full Text] [PDF]  

Cutting Edge: Oseltamivir Decreases T Cell GM1 Expression and Inhibits Clearance of Respiratory Syncytial Virus: Potential Role of Endogenous Sialidase in Antiviral Immunity

Martin L. Moore, Michael H. Chi, Weisong Zhou, Kasia Goleniewska, Jamye F. O’Neal, James N. Higginbotham, and R. Stokes Peebles, Jr.
J Immunol 2007 178: 2651-2654. [Abstract] [Full Text] [PDF]  

Cutting Edge: Differential Inhibition of TLR Signaling Pathways by Cell-Permeable Peptides Representing BB Loops of TLRs

Vladimir Y. Toshchakov, Matthew J. Fenton, and Stefanie N. Vogel
J Immunol 2007 178: 2655-2660. [Abstract] [Full Text] [PDF]  

Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

Mischo Kursar, Markus Koch, Hans-Willi Mittrücker, Geraldine Nouailles, Kerstin Bonhagen, Thomas Kamradt, and Stefan H. E. Kaufmann
J Immunol 2007 178: 2661-2665. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Murine Neonatal CD4⁺ Cells Are Poised for Rapid Th2 Effector-Like Function

Shawn Rose, Mathias Lichtenheld, Monica R. Foote, and Becky Adkins
J Immunol 2007 178: 2667-2678. [Abstract] [Full Text] [PDF]  

Apoptotic Cells Induce Tolerance by Generating Helpless CD8⁺ T Cells That Produce TRAIL

Thomas S. Griffith, Hirotaka Kazama, Rebecca L. VanOosten, James K. Earle, Jr., John M. Herndon, Douglas R. Green, and Thomas A. Ferguson
J Immunol 2007 178: 2679-2687. [Abstract] [Full Text] [PDF]  

NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection

Monia Draghi, Achal Pashine, Bharati Sanjanwala, Ketevan Gendzekhadze, Claudia Cantoni, David Cosman, Alessandro Moretta, Nicholas M. Valiante, and Peter Parham
J Immunol 2007 178: 2688-2698. [Abstract] [Full Text] [PDF]  

Immunization of Flavivirus West Nile Recombinant Envelope Domain III Protein Induced Specific Immune Response and Protection against West Nile Virus Infection

Jang-Hann J. Chu, Cern-Cher S. Chiang, and Mah-Lee Ng
J Immunol 2007 178: 2699-2705. [Abstract] [Full Text] [PDF]  

Invariant NKT Cells Amplify the Innate Immune Response to Lipopolysaccharide

Niranjana A. Nagarajan and Mitchell Kronenberg
J Immunol 2007 178: 2706-2713. [Abstract] [Full Text] [PDF]  

PD-1:PD-L1 Interactions Contribute to the Functional Suppression of Virus-Specific CD8⁺ T Lymphocytes in the Liver

Holly Maier, Masanori Isogawa, Gordon J. Freeman, and Francis V. Chisari
J Immunol 2007 178: 2714-2720. [Abstract] [Full Text] [PDF]  

Dendritic Cell Function Can Be Modulated through Cooperative Actions of TLR Ligands and Invariant NKT Cells

Ian F. Hermans, Jonathan D. Silk, Uzi Gileadi, S. Hajar Masri, Dawn Shepherd, Kathryn J. Farrand, Mariolina Salio, and Vincenzo Cerundolo
J Immunol 2007 178: 2721-2729. [Abstract] [Full Text] [PDF]  

Epigenetic and Transcriptional Programs Lead to Default IFN- Production by T Cells

Liang Chen, Weifeng He, Sean T. Kim, Jian Tao, Yunfei Gao, Hongbo Chi, Andrew M. Intlekofer, Bohdan Harvey, Steven L. Reiner, Zhinan Yin, Richard A. Flavell, and Joe Craft
J Immunol 2007 178: 2730-2736. [Abstract] [Full Text] [PDF]  

Virus-Specific CD8⁺ T Cells in the Liver: Armed and Ready to Kill

Rachael Keating, Wen Yue, John A. Rutigliano, Jenny So, Elvia Olivas, Paul G. Thomas, and Peter C. Doherty
J Immunol 2007 178: 2737-2745. [Abstract] [Full Text] [PDF]  

Gag-Specific CD8⁺ T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression

Jonah B. Sacha, Chungwon Chung, Eva G. Rakasz, Sean P. Spencer, Anna K. Jonas, Alexander T. Bean, Wonhee Lee, Benjamin J. Burwitz, Jason J. Stephany, John T. Loffredo, David B. Allison, Sama Adnan, Akihiko Hoji, Nancy A. Wilson, Thomas C. Friedrich, Jeffrey D. Lifson, Otto O. Yang, and David I. Watkins
J Immunol 2007 178: 2746-2754. [Abstract] [Full Text] [PDF]  

Efficient Activation of V14 Invariant NKT Cells by Foreign Lipid Antigen Is Associated with Concurrent Dendritic Cell-Specific Self Recognition

Lu Cheng, Aito Ueno, Suzanne Cho, Jin S. Im, Susanne Golby, Sheng Hou, Steven A. Porcelli, and Yang Yang
J Immunol 2007 178: 2755-2762. [Abstract] [Full Text] [PDF]  

Dendritic Cells Infiltrating Human Non-Small Cell Lung Cancer Are Blocked at Immature Stage

Ivan Perrot, Dominique Blanchard, Nathalie Freymond, Sylvie Isaac, Benoît Guibert, Yves Pachéco, and Serge Lebecque
J Immunol 2007 178: 2763-2769. [Abstract] [Full Text] [PDF]  

Fetal Immune Responses to Plasmodium falciparum Antigens in a Malaria-Endemic Region of Cameroon

Simon Metenou, Amorsolo L. Suguitan, Jr., Carole Long, Rose G. F. Leke, and Diane Wallace Taylor
J Immunol 2007 178: 2770-2777. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes

Jovanna González, Esther Tamayo, Inés Santiuste, Regina Marquina, Luis Buelta, Miguel A. González-Gay, Shozo Izui, Marcos López-Hoyos, Jesús Merino, and Ramón Merino
J Immunol 2007 178: 2778-2786. [Abstract] [Full Text] [PDF]  

Lack of Effective MUC1 Tumor Antigen-Specific Immunity in MUC1-Transgenic Mice Results from a Th/T Regulatory Cell Imbalance That Can Be Corrected by Adoptive Transfer of Wild-Type Th Cells

Michael S. Turner, Patrice A. Cohen, and Olivera J. Finn
J Immunol 2007 178: 2787-2793. [Abstract] [Full Text] [PDF]  

Effect of Both Ultraviolet B Irradiation and Histamine Receptor Function on Allergic Responses to an Inhaled Antigen

Jacqueline P. McGlade, Shelley Gorman, Jason C. Lenzo, Jamie W. Tan, Takeshi Watanabe, John J. Finlay-Jones, Wayne R. Thomas, and Prue H. Hart
J Immunol 2007 178: 2794-2802. [Abstract] [Full Text] [PDF]  

Staphylococcus aureus Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 Ligands

Isabelle Bekeredjian-Ding, Seiichi Inamura, Thomas Giese, Hermann Moll, Stefan Endres, Andreas Sing, Ulrich Zähringer, and Gunther Hartmann
J Immunol 2007 178: 2803-2812. [Abstract] [Full Text] [PDF]  

Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF- Involves Activation of the MKK6/p38^MAPK/MK2 Cascade

Christian Ehlting, Wi S. Lai, Fred Schaper, Erwin D. Brenndörfer, Raphaela-Jessica Matthes, Peter C. Heinrich, Stephan Ludwig, Perry J. Blackshear, Matthias Gaestel, Dieter Häussinger, and Johannes G. Bode
J Immunol 2007 178: 2813-2826. [Abstract] [Full Text] [PDF]  

IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production

Jonathan M. Coquet, Konstantinos Kyparissoudis, Daniel G. Pellicci, Gurdyal Besra, Stuart P. Berzins, Mark J. Smyth, and Dale I. Godfrey
J Immunol 2007 178: 2827-2834. [Abstract] [Full Text] [PDF]  

IL-2/Neuroantigen Fusion Proteins as Antigen-Specific Tolerogens in Experimental Autoimmune Encephalomyelitis (EAE): Correlation of T Cell-Mediated Antigen Presentation and Tolerance Induction

Mark D. Mannie, Barbara A. Clayson, Elizabeth J. Buskirk, Jarret L. DeVine, Jose J. Hernandez, and Derek J. Abbott
J Immunol 2007 178: 2835-2843. [Abstract] [Full Text] [PDF]  

CD40-CD40 Ligand Interaction between Dendritic Cells and CD8⁺ T Cells Is Needed to Stimulate Maximal T Cell Responses in the Absence of CD4⁺ T Cell Help

Maria Genevive H. Hernandez, Lianjun Shen, and Kenneth L. Rock
J Immunol 2007 178: 2844-2852. [Abstract] [Full Text] [PDF]  

Tumor Cells Loaded with -Galactosylceramide Induce Innate NKT and NK Cell-Dependent Resistance to Tumor Implantation in Mice

Kanako Shimizu, Akira Goto, Mikiko Fukui, Masaru Taniguchi, and Shin-ichiro Fujii
J Immunol 2007 178: 2853-2861. [Abstract] [Full Text] [PDF]  

Involvement of Src and Syk Tyrosine Kinases in HIV-1 Transfer from Dendritic Cells to CD4⁺ T Lymphocytes

Caroline Gilbert, Corinne Barat, Réjean Cantin, and Michel J. Tremblay
J Immunol 2007 178: 2862-2871. [Abstract] [Full Text] [PDF]  

IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells

Rachel Ettinger, Gary P. Sims, Rachel Robbins, David Withers, Randy T. Fischer, Amrie C. Grammer, Stefan Kuchen, and Peter E. Lipsky
J Immunol 2007 178: 2872-2882. [Abstract] [Full Text] [PDF]  

Tumor Evasion of the Immune System by Converting CD4⁺CD25^– T Cells into CD4⁺CD25⁺ T Regulatory Cells: Role of Tumor-Derived TGF-

Victoria C. Liu, Larry Y. Wong, Thomas Jang, Ali H. Shah, Irwin Park, Ximing Yang, Qiang Zhang, Scott Lonning, Beverly A. Teicher, and Chung Lee
J Immunol 2007 178: 2883-2892. [Abstract] [Full Text] [PDF]  

Induced SHIP Deficiency Expands Myeloid Regulatory Cells and Abrogates Graft-versus-Host Disease

Kim H. T. Paraiso, Tomar Ghansah, Amy Costello, Robert W. Engelman, and William G. Kerr
J Immunol 2007 178: 2893-2900. [Abstract] [Full Text] [PDF]  

Augmentation of Signaling through BCR Containing IgE but not That Containing IgA Due to Lack of CD22-Mediated Signal Regulation

Motohiko Sato, Takahiro Adachi, and Takeshi Tsubata
J Immunol 2007 178: 2901-2907. [Abstract] [Full Text] [PDF]  

Modulation of CD103 Expression on Human Colon Carcinoma-Specific CTL

Khoon-Lin Ling, Nicolas Dulphy, Pru Bahl, Mariolina Salio, Kevin Maskell, Juan Piris, Bryan F. Warren, Bruce D. George, Neil J. Mortensen, and Vincenzo Cerundolo
J Immunol 2007 178: 2908-2915. [Abstract] [Full Text] [PDF]  

Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice

Helen Ferry, Paul K. Potter, Tanya L. Crockford, Anastasia Nijnik, Michael R. Ehrenstein, Mark J. Walport, Marina Botto, and Richard J. Cornall
J Immunol 2007 178: 2916-2922. [Abstract] [Full Text] [PDF]  

Mcl-1 Depletion in Apoptosis Elicited by Ionizing Radiation in Peritoneal Resident Macrophages of C3H Mice

Yoshihisa Kubota, Keiji Kinoshita, Katsutoshi Suetomi, Akira Fujimori, and Sentaro Takahashi
J Immunol 2007 178: 2923-2931. [Abstract] [Full Text] [PDF]  

CD4⁺ and CD8⁺ T Cell Survival Is Regulated Differentially by Protein Kinase C, c-Rel, and Protein Kinase B

Samuel D. Saibil, Russell G. Jones, Elissa K. Deenick, Nicole Liadis, Alisha R. Elford, Mitchell G. Vainberg, Heather Baerg, James R. Woodgett, Steve Gerondakis, and Pamela S. Ohashi
J Immunol 2007 178: 2932-2939. [Abstract] [Full Text] [PDF]  

Peroxisome Proliferator-Activated Receptor Is Required for Regulatory CD4⁺ T Cell-Mediated Protection against Colitis

Raquel Hontecillas and Josep Bassaganya-Riera
J Immunol 2007 178: 2940-2949. [Abstract] [Full Text] [PDF]  

Fitness of Cell-Mediated Immunity Independent of Repertoire Diversity

Mouhammed AbuAttieh, Michelle Rebrovich, Peter J. Wettstein, Zvezdana Vuk-Pavlovic, Andrew H. Limper, Jeffrey L. Platt, and Marilia Cascalho
J Immunol 2007 178: 2950-2960. [Abstract] [Full Text] [PDF]  

Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen

Dipica Haribhai, Wen Lin, Lance M. Relland, Nga Truong, Calvin B. Williams, and Talal A. Chatila
J Immunol 2007 178: 2961-2972. [Abstract] [Full Text] [PDF]  

CC Chemokine Receptor 7 Contributes to Gi-Dependent T Cell Motility in the Lymph Node

Takaharu Okada and Jason G. Cyster
J Immunol 2007 178: 2973-2978. [Abstract] [Full Text] [PDF] Data Supplement  

Targeting of Antigen to Dendritic Cells with Poly(-Glutamic Acid) Nanoparticles Induces Antigen-Specific Humoral and Cellular Immunity

Tomofumi Uto, Xin Wang, Katsuaki Sato, Misako Haraguchi, Takami Akagi, Mitsuru Akashi, and Masanori Baba
J Immunol 2007 178: 2979-2986. [Abstract] [Full Text] [PDF]  

Requirement for a Complex of Wiskott-Aldrich Syndrome Protein (WASP) with WASP Interacting Protein in Podosome Formation in Macrophages

Shigeru Tsuboi
J Immunol 2007 178: 2987-2995. [Abstract] [Full Text] [PDF]  

Anti-Nuclear Antibody Production and Autoimmunity in Transgenic Mice That Overexpress the Transcription Factor Bright

Malini Shankar, Jamee C. Nixon, Shannon Maier, Jennifer Workman, A. Darise Farris, and Carol F. Webb
J Immunol 2007 178: 2996-3006. [Abstract] [Full Text] [PDF]  

Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation

Geoffrey O. Gillard, James Dooley, Matthew Erickson, Leena Peltonen, and Andrew G. Farr
J Immunol 2007 178: 3007-3015. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Conformational Changes in Mannan-Binding Lectin Bound to Ligand Surfaces

Mingdong Dong, Sailong Xu, Cristiano L. P. Oliveira, Jan S. Pedersen, Steffen Thiel, Flemming Besenbacher, and Thomas Vorup-Jensen
J Immunol 2007 178: 3016-3022. [Abstract] [Full Text] [PDF]  

Genomic Organization of the Chicken CD8 Locus Reveals a Novel Family of Immunoreceptor Genes

Hung-Jiun Liaw, Wei-Ru Chen, Yu-Chia Huang, Chung-Wei Tsai, King-Chan Chang, and Chia-Lam Kuo
J Immunol 2007 178: 3023-3030. [Abstract] [Full Text] [PDF]  

Early Growth Response Transcriptional Regulators Are Dispensable for Macrophage Differentiation

John H. Carter and Warren G. Tourtellotte
J Immunol 2007 178: 3038-3047. [Abstract] [Full Text] [PDF]  

Transmembrane Mutations to FcRIIA Alter Its Association with Lipid Rafts: Implications for Receptor Signaling

Erick García-García, Eric J. Brown, and Carlos Rosales
J Immunol 2007 178: 3048-3058. [Abstract] [Full Text] [PDF]  

17-Estradiol Induces IL-1 Gene Expression in Rheumatoid Fibroblast-Like Synovial Cells through Estrogen Receptor (ER) and Augmentation of Transcriptional Activity of Sp1 by Dissociating Histone Deacetylase 2 from ER

Yuka Itoh, Hidetoshi Hayashi, Keiji Miyazawa, Soichi Kojima, Tohru Akahoshi, and Kikuo Onozaki
J Immunol 2007 178: 3059-3066. [Abstract] [Full Text] [PDF]  

NF-AT-Mediated Expression of TGF-1 in Tolerant T Cells

Naoko Nakano, Hiroyuki Hosokawa, Masako Kohyama, and Nobumichi Hozumi
J Immunol 2007 178: 3067-3075. [Abstract] [Full Text] [PDF]  

ARTICLES:

Reporter Gene Insertions Reveal a Strictly B Lymphoid-Specific Expression Pattern of Pax5 in Support of Its B Cell Identity Function

Martin Fuxa and Meinrad Busslinger
J Immunol 2007 178: 3031-3037. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

HLA Transgenic Mice Provide Evidence for a Direct and Dominant Role of HLA Class II Variation in Modulating the Severity of Streptococcal Sepsis

Mohammed M. Nooh, Nagala El-Gengehi, Rita Kansal, Chella S. David, and Malak Kotb
J Immunol 2007 178: 3076-3083. [Abstract] [Full Text] [PDF]  

Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci

Emma Ahlqvist, Robert Bockermann, and Rikard Holmdahl
J Immunol 2007 178: 3084-3090. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Hidden Epitopes Emerge in Secondary Influenza Virus-Specific CD8⁺ T Cell Reponses

Paul G. Thomas, Scott A. Brown, Rachael Keating, Wen Yue, Melissa Y. Morris, Jenny So, Richard J. Webby, and Peter C. Doherty
J Immunol 2007 178: 3091-3098. [Abstract] [Full Text] [PDF]  

A Novel Antibody-Dependent Cellular Cytotoxicity Mechanism Involved in Defense against Malaria Requires Costimulation of Monocytes FcRII and FcRIII

Ali Jafarshad, Morten H. Dziegiel, Rasmus Lundquist, Leif K. Nielsen, Subhash Singh, and Pierre L. Druilhe
J Immunol 2007 178: 3099-3106. [Abstract] [Full Text] [PDF]  

Dectin-1 Stimulation by Candida albicans Yeast or Zymosan Triggers NFAT Activation in Macrophages and Dendritic Cells

Helen S. Goodridge, Randi M. Simmons, and David M. Underhill
J Immunol 2007 178: 3107-3115. [Abstract] [Full Text] [PDF] Data Supplement  

Human Peptidoglycan Recognition Proteins Require Zinc to Kill Both Gram-Positive and Gram-Negative Bacteria and Are Synergistic with Antibacterial Peptides

Minhui Wang, Li-Hui Liu, Shiyong Wang, Xinna Li, Xiaofeng Lu, Dipika Gupta, and Roman Dziarski
J Immunol 2007 178: 3116-3125. [Abstract] [Full Text] [PDF]  

Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria

Giuseppe Mancuso, Angelina Midiri, Carmelo Biondo, Concetta Beninati, Sebastiana Zummo, Roberta Galbo, Francesco Tomasello, Maria Gambuzza, Giancarlo Macrì, Alessia Ruggeri, Tomas Leanderson, and Giuseppe Teti
J Immunol 2007 178: 3126-3133. [Abstract] [Full Text] [PDF]  

Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells

Anja K. Mayer, Mario Muehmer, Jörg Mages, Katja Gueinzius, Christian Hess, Klaus Heeg, Robert Bals, Roland Lang, and Alexander H. Dalpke
J Immunol 2007 178: 3134-3142. [Abstract] [Full Text] [PDF] Data Supplement  

The Type I IFN Response to Infection with Mycobacterium tuberculosis Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis

Sarah A. Stanley, James E. Johndrow, Paolo Manzanillo, and Jeffery S. Cox
J Immunol 2007 178: 3143-3152. [Abstract] [Full Text] [PDF]  

Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN- (TRIF)-Mediated Signaling Contributes to Innate Immune Responses in the Lung during Escherichia coli Pneumonia

Samithamby Jeyaseelan, Scott K. Young, Michael B. Fessler, Yuhong Liu, Kenneth C. Malcolm, Masahiro Yamamoto, Shizuo Akira, and G. Scott Worthen
J Immunol 2007 178: 3153-3160. [Abstract] [Full Text] [PDF]  

Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and ₁ Integrin-Mediated Pathway

Marie-Pierre Puissegur, Guillaume Lay, Martine Gilleron, Laure Botella, Jérôme Nigou, Hedia Marrakchi, Bernard Mari, Jean-Luc Duteyrat, Yann Guerardel, Laurent Kremer, Pascal Barbry, Germain Puzo, and Frédéric Altare
J Immunol 2007 178: 3161-3169. [Abstract] [Full Text] [PDF]  

A Role of Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing IFN- in the Host Response to Pseudomonas aeruginosa Lung Infection in Mice

Melanie R. Power, Bo Li, Masahiro Yamamoto, Shizuo Akira, and Tong-Jun Lin
J Immunol 2007 178: 3170-3176. [Abstract] [Full Text] [PDF]  

Efficient Capture of Antibody Neutralized HIV-1 by Cells Expressing DC-SIGN and Transfer to CD4⁺ T Lymphocytes

Thijs van Montfort, Alexey A. Nabatov, Teunis B. H. Geijtenbeek, Georgios Pollakis, and William A. Paxton
J Immunol 2007 178: 3177-3185. [Abstract] [Full Text] [PDF]  

TLR9 Expression and Function Is Abolished by the Cervical Cancer-Associated Human Papillomavirus Type 16

Uzma A. Hasan, Elizabeth Bates, Fumihiko Takeshita, Alexandra Biliato, Rosita Accardi, Veronique Bouvard, Mariam Mansour, Isabelle Vincent, Lutz Gissmann, Thomas Iftner, Mario Sideri, Frank Stubenrauch, and Massimo Tommasino
J Immunol 2007 178: 3186-3197. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF-B and Hypoxia-Inducible Factor-1

Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler
J Immunol 2007 178: 3198-3207. [Abstract] [Full Text] [PDF] Data Supplement  

Retinoid-Related Orphan Receptor Controls Immunoglobulin Production and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen

Stephen L. Tilley, Maisa Jaradat, Cliona Stapleton, Darlene Dixon, Xiaoyang Hua, Christopher J. Erikson, Joshua G. McCaskill, Kelly D. Chason, Grace Liao, Leigh Jania, Beverly H. Koller, and Anton M. Jetten
J Immunol 2007 178: 3208-3218. [Abstract] [Full Text] [PDF]  

TLR4 Hyperresponsiveness via Cell Surface Expression of Heat Shock Protein gp96 Potentiates Suppressive Function of Regulatory T Cells

Jie Dai, Bei Liu, Soo Mun Ngoi, Shaoli Sun, Anthony T. Vella, and Zihai Li
J Immunol 2007 178: 3219-3225. [Abstract] [Full Text] [PDF]  

Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia

Ziye Sui, Lynn F. Sniderhan, Giovanni Schifitto, Richard P. Phipps, Harris A. Gelbard, Stephen Dewhurst, and Sanjay B. Maggirwar
J Immunol 2007 178: 3226-3236. [Abstract] [Full Text] [PDF]  

TCR Signaling Antagonizes Rapid IP-10-Mediated Transendothelial Migration of Effector Memory CD4⁺ T Cells

Thomas D. Manes, Stephen L. Shiao, Thomas J. Dengler, and Jordan S. Pober
J Immunol 2007 178: 3237-3243. [Abstract] [Full Text] [PDF]  

IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells

Valérie Steenwinckel, Jamila Louahed, Ciriana Orabona, François Huaux, Guy Warnier, Andrew McKenzie, Dominique Lison, Roy Levitt, and Jean-Christophe Renauld
J Immunol 2007 178: 3244-3251. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Rate of Increase in Circulating IL-7 and Loss of IL-7R Expression Differ in HIV-1 and HIV-2 Infections: Two Lymphopenic Diseases with Similar Hyperimmune Activation but Distinct Outcomes

Adriana S. Albuquerque, Catarina S. Cortesão, Russell B. Foxall, Rui S. Soares, Rui M. M. Victorino, and Ana E. Sousa
J Immunol 2007 178: 3252-3259. [Abstract] [Full Text] [PDF]  

Immunotherapy of Tumors with Neuroimmune Ligand Capsaicin

Jacqueline Beltran, Amiya K. Ghosh, and Sreyashi Basu
J Immunol 2007 178: 3260-3264. [Abstract] [Full Text] [PDF]  

HIV-Specific IL-10-Positive CD8⁺ T Cells Suppress Cytolysis and IL-2 Production by CD8⁺ T Cells

Mohamed Elrefaei, Florence L. Ventura, Chris A. R. Baker, Richard Clark, David R. Bangsberg, and Huyen Cao
J Immunol 2007 178: 3265-3271. [Abstract] [Full Text] [PDF]  

Expression Profile of FcRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus

Kaihong Su, Hengxuan Yang, Xinrui Li, Xiaoli Li, Andrew W. Gibson, John M. Cafardi, Tong Zhou, Jeffrey C. Edberg, and Robert P. Kimberly
J Immunol 2007 178: 3272-3280. [Abstract] [Full Text] [PDF]  

Aberrant Expression of the Insulin-Like Growth Factor-1 Receptor by T Cells from Patients with Graves’ Disease May Carry Functional Consequences for Disease Pathogenesis

Raymond S. Douglas, Andrew G. Gianoukakis, Shweta Kamat, and Terry J. Smith
J Immunol 2007 178: 3281-3287. [Abstract] [Full Text] [PDF]  

Involvement of C-C Chemokine Ligand 2-CCR2 Interaction in Monocyte-Lineage Cell Recruitment of Normal Human Corneal Stroma

Nobuyuki Ebihara, Satoru Yamagami, Seiichi Yokoo, Shiro Amano, and Akira Murakami
J Immunol 2007 178: 3288-3292. [Abstract] [Full Text] [PDF]  

Phenotype and Effector Function of CC Chemokine Receptor 9-Expressing Lymphocytes in Small Intestinal Crohn’s Disease

Masayuki Saruta, Qi T. Yu, Armine Avanesyan, Phillip R. Fleshner, Stephan R. Targan, and Konstantinos A. Papadakis
J Immunol 2007 178: 3293-3300. [Abstract] [Full Text] [PDF]  

Enhanced Antitumor Responses Elicited by Combinatorial Protein Transfer of Chemotactic and Costimulatory Molecules

Shanrong Liu, Deborah R. Breiter, Guoxing Zheng, and Aoshuang Chen
J Immunol 2007 178: 3301-3306. [Abstract] [Full Text] [PDF]  

Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis

Maud Condomines, Dirk Hose, Pierre Raynaud, Michael Hundemer, John De Vos, Marion Baudard, Thomas Moehler, Véronique Pantesco, Marion Moos, Jean-François Schved, Jean-François Rossi, Thierry Rème, Hartmut Goldschmidt, and Bernard Klein
J Immunol 2007 178: 3307-3315. [Abstract] [Full Text] [PDF]  

A Critical Role for Allograft Inflammatory Factor-1 in the Pathogenesis of Rheumatoid Arthritis

Mizuho Kimura, Yutaka Kawahito, Hiroshi Obayashi, Mitsuhiro Ohta, Hirokazu Hara, Tetsuo Adachi, Daisaku Tokunaga, Tatsuya Hojo, Masahide Hamaguchi, Atsushi Omoto, Hidetaka Ishino, Makoto Wada, Masataka Kohno, Yasunori Tsubouchi, and Toshikazu Yoshikawa
J Immunol 2007 178: 3316-3322. [Abstract] [Full Text] [PDF]  

C3d Binding to the Myelin Oligodendrocyte Glycoprotein Results in an Exacerbated Experimental Autoimmune Encephalomyelitis

Jean-François Jégou, Philippe Chan, Marie-Thérèse Schouft, Mark R. Griffiths, James W. Neal, Philippe Gasque, Hubert Vaudry, and Marc Fontaine
J Immunol 2007 178: 3323-3331. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

S. N. Waggoner, M. W. Cruise, R. Kassel, and Y. S. Hahn
J Immunol 2007 178: 3332. [Full Text] [PDF]  

The engagement of activating FcRs inhibits primate lentivirus replication in human macrophages

A. David, A. Sáez-Cirión, P. Versmisse, O. Malbec, B. Iannascoli, F. Herschke, M. Lucas, F. Barré-Sinoussi, J.-F. Mouscadet, M. Daëron, and G. Pancino
J Immunol 2007 178: 3333. [Full Text] [PDF]  

Induction of vascular leakage and blood pressure lowering through kinin release by a serine proteinase from Aeromonas sobria

T. Imamura, H. Kobayashi, R. Khan, H. Nitta, and K. Okamoto
J Immunol 2007 178: 3333. [Full Text] [PDF]  

Urinary bladder epithelium antigen induces CD8⁺ T cell tolerance, activation, and autoimmune response

W. Liu, D. P. Evanoff, X. Chen, and Y. Luo
J Immunol 2007 178: 3333. [Full Text] [PDF]  

HIV-1 Trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons

J. P. Norman, S. W. Perry, K. A. Kasischke, D. J. Volsky, and H. A. Gelbard
J Immunol 2007 178: 3334. [Full Text] [PDF]  

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