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On the cover: Whole mount immunostainings of the intestines of wild-type and tnfr1-/- mice with anti-VCAM-1 (upper panels) or anti-CXCL13 (lower panels) antibody. Accumulation of VCAM-1 positive stromal cells and expression of CXCL13 (brown spots) in Peyer's patch anlagen were severely impaired in tnfr1-/- mice (right panels) compared to wild-type mice (left panels). Piao, J.-H., H. Yoshida, W.-C. Yeh, T. Doi, X. Xue, H. Yagita, K. Okumura, and H. Nakano. 2007. TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches. J. Immunol. 178: 2272–2277.
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