IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2005 175: 4159-4160. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

One for One Peptide Binding to MHC Molecules

Janice S. Blum
J Immunol 2005 175: 4161-4162. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Binding of Immunogenic Peptides to Ia Histocompatibility Molecules. Nature. 1985. 317: 359–361.

Bruce P. Babbitt, Paul M. Allen, Gary Matsueda, Edgar Haber, and Emil R. Unanue
J Immunol 2005 175: 4163-4165. [PDF]  

BRIEF REVIEWS:

Mast Cell Survival and Activation by IgE in the Absence of Antigen: A Consideration of the Biologic Mechanisms and Relevance

Toshiaki Kawakami and Jiro Kitaura
J Immunol 2005 175: 4167-4173. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling

Michael V. Lasker, Mark M. Gajjar, and Satish K. Nair
J Immunol 2005 175: 4175-4179. [Abstract] [Full Text] [PDF]  

Cutting Edge: Direct Suppression of B Cells by CD4⁺CD25⁺ Regulatory T Cells

Hyung W. Lim, Peter Hillsamer, Allison H. Banham, and Chang H. Kim
J Immunol 2005 175: 4180-4183. [Abstract] [Full Text] [PDF]  

Cutting Edge: Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Generates a Population of CD4⁺CD25⁺ Cells with Characteristics of Regulatory T Cells

Castle J. Funatake, Nikki B. Marshall, Linda B. Steppan, Dan V. Mourich, and Nancy I. Kerkvliet
J Immunol 2005 175: 4184-4188. [Abstract] [Full Text] [PDF]  

Cutting Edge: TLR2-Mediated Proinflammatory Cytokine and Chemokine Production by Microglial Cells in Response to Herpes Simplex Virus

Rajagopal N. Aravalli, Shuxian Hu, Timothy N. Rowen, Joseph M. Palmquist, and James R. Lokensgard
J Immunol 2005 175: 4189-4193. [Abstract] [Full Text] [PDF]  

Cutting Edge: Bacterial Modulation of Epithelial Signaling via Changes in Neddylation of Cullin-1

Lauren S. Collier-Hyams, Valerie Sloane, Brigid C. Batten, and Andrew S. Neish
J Immunol 2005 175: 4194-4198. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Regulated Costimulation in the Thymus Is Critical for T Cell Development: Dysregulated CD28 Costimulation Can Bypass the Pre-TCR Checkpoint

Joy A. Williams, Karen S. Hathcock, David Klug, Yohsuke Harada, Baishakhi Choudhury, James P. Allison, Ryo Abe, and Richard J. Hodes
J Immunol 2005 175: 4199-4207. [Abstract] [Full Text] [PDF]  

CIN85 Regulates the Ligand-Dependent Endocytosis of the IgE Receptor: A New Molecular Mechanism to Dampen Mast Cell Function

Rosa Molfetta, Francesca Belleudi, Giovanna Peruzzi, Stefania Morrone, Laura Leone, Ivan Dikic, Mario Piccoli, Luigi Frati, Maria Rosaria Torrisi, Angela Santoni, and Rossella Paolini
J Immunol 2005 175: 4208-4216. [Abstract] [Full Text] [PDF]  

Absence of Leukotriene B₄ Receptor 1 Confers Resistance to Airway Hyperresponsiveness and Th2-Type Immune Responses

Kan Terawaki, Takehiko Yokomizo, Takahide Nagase, Akiko Toda, Masahiko Taniguchi, Kohei Hashizume, Takeshi Yagi, and Takao Shimizu
J Immunol 2005 175: 4217-4225. [Abstract] [Full Text] [PDF]  

The Adaptor Protein 3BP2 Binds Human CD244 and Links this Receptor to Vav Signaling, ERK Activation, and NK Cell Killing

Ifigènia Saborit-Villarroya, Juana M. Del Valle, Xavier Romero, Enric Esplugues, Pilar Lauzurica, Pablo Engel, and Margarita Martín
J Immunol 2005 175: 4226-4235. [Abstract] [Full Text] [PDF]  

The Mannich Base NC1153 Promotes Long-Term Allograft Survival and Spares the Recipient from Multiple Toxicities

Stanislaw M. Stepkowski, Judy Kao, Mou-Er Wang, Neelam Tejpal, Hemangshu Podder, Lucrezia Furian, Jonathan Dimmock, Amitabh Jha, Umashankar Das, Barry D. Kahan, and Robert A. Kirken
J Immunol 2005 175: 4236-4246. [Abstract] [Full Text] [PDF]  

Maintenance of Immune Tolerance Depends on Normal Tissue Homeostasis

Zita F. H. M. Boonman, Geertje J. D. van Mierlo, Marieke F. Fransen, Rob J. W. de Keizer, Martine J. Jager, Cornelis J. M. Melief, and René E. M. Toes
J Immunol 2005 175: 4247-4254. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ Regulatory T Cells Inhibit the Maturation but Not the Initiation of an Autoantibody Response

Michele L. Fields, Brian D. Hondowicz, Michele H. Metzgar, Simone A. Nish, Gina N. Wharton, Cristina C. Picca, Andrew J. Caton, and Jan Erikson
J Immunol 2005 175: 4255-4264. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin/CD209 Is Abundant on Macrophages in the Normal Human Lymph Node and Is Not Required for Dendritic Cell Stimulation of the Mixed Leukocyte Reaction

Angela Granelli-Piperno, Alla Pritsker, Maggi Pack, Irina Shimeliovich, Jean-Francois Arrighi, Chae Gyu Park, Christine Trumpfheller, Vincent Piguet, Thomas M. Moran, and Ralph M. Steinman
J Immunol 2005 175: 4265-4273. [Abstract] [Full Text] [PDF]  

Absence of Caprin-1 Results in Defects in Cellular Proliferation

Bin Wang, Muriel D. David, and John W. Schrader
J Immunol 2005 175: 4274-4282. [Abstract] [Full Text] [PDF]  

Protection against Autoimmunity in Nonlymphopenic Hosts by CD4⁺CD25⁺ Regulatory T Cells Is Antigen-Specific and Requires IL-10 and TGF-

Xiaopei Huang, Jiangao Zhu, and Yiping Yang
J Immunol 2005 175: 4283-4291. [Abstract] [Full Text] [PDF]  

Immunostimulatory CpG Oligonucleotides Abrogate Allergic Susceptibility in a Murine Model of Maternal Asthma Transmission

Alexey Fedulov, Eric Silverman, Yuhong Xiang, Adriana Leme, and Lester Kobzik
J Immunol 2005 175: 4292-4300. [Abstract] [Full Text] [PDF]  

Virus-Induced Inhibition of CD1d1-Mediated Antigen Presentation: Reciprocal Regulation by p38 and ERK

Gourapura J. Renukaradhya, Tonya J. Roberts Webb, Masood A. Khan, Yin Ling Lin, Wenjun Du, Jacquelyn Gervay-Hague, and Randy R. Brutkiewicz
J Immunol 2005 175: 4301-4308. [Abstract] [Full Text] [PDF]  

Colocalization of Expansion of the Splenic Marginal Zone Population with Abnormal B Cell Activation and Autoantibody Production in B6 Mice with an Introgressed New Zealand Black Chromosome 13 Interval

Joan E. Wither, Christina Loh, Ginette Lajoie, Svinda Heinrichs, Yong-Chun Cai, Gabriel Bonventi, and Ralph MacLeod
J Immunol 2005 175: 4309-4319. [Abstract] [Full Text] [PDF]  

TLR Signaling Tailors Innate Immune Responses in Human Microglia and Astrocytes

Carolyn S. Jack, Nathalie Arbour, Joshua Manusow, Vivianne Montgrain, Manon Blain, Ellie McCrea, Aaron Shapiro, and Jack P. Antel
J Immunol 2005 175: 4320-4330. [Abstract] [Full Text] [PDF]  

An Organized Medullary Epithelial Structure in the Normal Thymus Expresses Molecules of Respiratory Epithelium and Resembles the Epithelial Thymic Rudiment of Nude Mice

James Dooley, Matt Erickson, and Andrew G. Farr
J Immunol 2005 175: 4331-4337. [Abstract] [Full Text] [PDF]  

Activation of Dendritic Cells via Inhibition of Jak2/STAT3 Signaling

Yulia Nefedova, Pingyan Cheng, Daniele Gilkes, Michelle Blaskovich, Amer A. Beg, Said M. Sebti, and Dmitry I. Gabrilovich
J Immunol 2005 175: 4338-4346. [Abstract] [Full Text] [PDF]  

Diabetes Is Predicted by the Cell Level of Autoantigen

Craig A. Byersdorfer, George G. Schweitzer, and Emil R. Unanue
J Immunol 2005 175: 4347-4354. [Abstract] [Full Text] [PDF]  

_E7 (CD103) Expression Identifies a Highly Active, Tonsil-Resident Effector-Memory CTL Population

Tonia Woodberry, Todd J. Suscovich, Leah M. Henry, Meredith August, Michael T. Waring, Amitinder Kaur, Christoph Hess, Jeffery L. Kutok, Jon C. Aster, Frederick Wang, David T. Scadden, and Christian Brander
J Immunol 2005 175: 4355-4362. [Abstract] [Full Text] [PDF]  

Stepwise Development of Committed Progenitors in the Bone Marrow That Generate Functional T Cells in the Absence of the Thymus

Marcos E. García-Ojeda, Sussan Dejbakhsh-Jones, Devavani Chatterjea-Matthes, Aditi Mukhopadhyay, Andrew BitMansour, Irving L. Weissman, Janice M. Y. Brown, and Samuel Strober
J Immunol 2005 175: 4363-4373. [Abstract] [Full Text] [PDF]  

The Death Receptor Fas (CD95/APO-1) Mediates the Deletion of T Lymphocytes Undergoing Homeostatic Proliferation

Karen A. Fortner and Ralph C. Budd
J Immunol 2005 175: 4374-4382. [Abstract] [Full Text] [PDF]  

G_s Protein-Coupled Adenosine Receptor Signaling and Lytic Function of Activated NK Cells

Tatiana Raskovalova, Xiaojun Huang, Michail Sitkovsky, Lefteris C. Zacharia, Edwin K. Jackson, and Elieser Gorelik
J Immunol 2005 175: 4383-4391. [Abstract] [Full Text] [PDF]  

Signal 3 Tolerant CD8 T Cells Degranulate in Response to Antigen but Lack Granzyme B to Mediate Cytolysis

Julie M. Curtsinger, Debra C. Lins, Christopher M. Johnson, and Matthew F. Mescher
J Immunol 2005 175: 4392-4399. [Abstract] [Full Text] [PDF]  

IL-7 Receptor Expression Levels Do Not Identify CD8⁺ Memory T Lymphocyte Precursors following Peptide Immunization

Marie-Hélène Lacombe, Marie-Pierre Hardy, Julie Rooney, and Nathalie Labrecque
J Immunol 2005 175: 4400-4407. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide-Induced Heme Oxygenase-1 Expression in Human Monocytic Cells Is Mediated via Nrf2 and Protein Kinase C

Stuart A. Rushworth, Xi-Lin Chen, Nigel Mackman, Richard M. Ogborne, and Maria A. O’Connell
J Immunol 2005 175: 4408-4415. [Abstract] [Full Text] [PDF]  

DX5/CD49b-Positive T Cells Are Not Synonymous with CD1d-Dependent NKT Cells

Daniel G. Pellicci, Kirsten J. L. Hammond, Jonathan Coquet, Konstantinos Kyparissoudis, Andrew G. Brooks, Katherine Kedzierska, Rachael Keating, Stephen Turner, Stuart Berzins, Mark J. Smyth, and Dale I. Godfrey
J Immunol 2005 175: 4416-4425. [Abstract] [Full Text] [PDF]  

Murine CD160, Ig-Like Receptor on NK Cells and NKT Cells, Recognizes Classical and Nonclassical MHC Class I and Regulates NK Cell Activation

Motoi Maeda, Carmine Carpenito, Ryan C. Russell, Jyoti Dasanjh, Linnea L. Veinotte, Hideaki Ohta, Takashi Yamamura, Rusung Tan, and Fumio Takei
J Immunol 2005 175: 4426-4432. [Abstract] [Full Text] [PDF]  

IFN- Controls the Generation/Activation of CD4⁺CD25⁺ Regulatory T Cells in Antitumor Immune Response

Hiroyoshi Nishikawa, Takuma Kato, Isao Tawara, Hiroaki Ikeda, Kagemasa Kuribayashi, Paul M. Allen, Robert D. Schreiber, Lloyd J. Old, and Hiroshi Shiku
J Immunol 2005 175: 4433-4440. [Abstract] [Full Text] [PDF]  

Down-Regulation of Basophil Function by Human CD200 and Human Herpesvirus-8 CD200

Ikuo Shiratori, Masao Yamaguchi, Maho Suzukawa, Kazuhiko Yamamoto, Lewis L. Lanier, Takashi Saito, and Hisashi Arase
J Immunol 2005 175: 4441-4449. [Abstract] [Full Text] [PDF]  

Binding of IgG-Opsonized Particles to FcR Is an Active Stage of Phagocytosis That Involves Receptor Clustering and Phosphorylation

Andrzej Sobota, Agnieszka Strzelecka-Kiliszek, Ewelina Gladkowska, Kiyotsugu Yoshida, Kazimiera Mrozinska, and Katarzyna Kwiatkowska
J Immunol 2005 175: 4450-4457. [Abstract] [Full Text] [PDF]  

Loss of IL-4 Secretion from Human Type 1a Diabetic Pancreatic Draining Lymph Node NKT Cells

Sally C. Kent, Yahua Chen, Sue M. Clemmings, Vissia Viglietta, Norma Sue Kenyon, Camillo Ricordi, Bernhard Hering, and David A. Hafler
J Immunol 2005 175: 4458-4464. [Abstract] [Full Text] [PDF]  

Analyzing Expression of Perforin, Runx3, and Thpok Genes during Positive Selection Reveals Activation of CD8-Differentiation Programs by MHC II-Signaled Thymocytes

Xiaolong Liu, Barbara J. Taylor, Guangping Sun, and Rémy Bosselut
J Immunol 2005 175: 4465-4474. [Abstract] [Full Text] [PDF]  

Reduction of Runx1 Transcription Factor Activity Up-Regulates Fas and Bim Expression and Enhances the Apoptotic Sensitivity of Double Positive Thymocytes

Natsumi Abe, Kazuyoshi Kohu, Hidetaka Ohmori, Keitaro Hayashi, Toshio Watanabe, Katsuto Hozumi, Takehito Sato, Sonoko Habu, and Masanobu Satake
J Immunol 2005 175: 4475-4482. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Phosphotyrosine Binding-Mediated Oligomerization of Downstream of Tyrosine Kinase (Dok)-1 and Dok-2 Is Involved in CD2-Induced Dok Phosphorylation

Iohann Boulay, Jean-Guy Némorin, and Pascale Duplay
J Immunol 2005 175: 4483-4489. [Abstract] [Full Text] [PDF]  

MD-2 Mediates the Ability of Tetra-Acylated and Penta-Acylated Lipopolysaccharides to Antagonize Escherichia coli Lipopolysaccharide at the TLR4 Signaling Complex

Stephen R. Coats, Thu-Thao T. Pham, Brian W. Bainbridge, Robert A. Reife, and Richard P. Darveau
J Immunol 2005 175: 4490-4498. [Abstract] [Full Text] [PDF]  

A Novel NF-B-Regulated Site within the Human I1 Promoter Requires p300 for Optimal Transcriptional Activity

Rebecca L. Dryer and Lori R. Covey
J Immunol 2005 175: 4499-4507. [Abstract] [Full Text] [PDF]  

Two Divergent Isotypes of the Fourth Complement Component from a Bony Fish, the Common Carp (Cyprinus carpio)

Junichi Mutsuro, Noriyuki Tanaka, Yoko Kato, Alister W. Dodds, Tomoki Yano, and Miki Nakao
J Immunol 2005 175: 4508-4517. [Abstract] [Full Text] [PDF]  

Id3 Induces Growth Arrest and Caspase-2-Dependent Apoptosis in B Lymphocyte Progenitors

Barbara L. Kee
J Immunol 2005 175: 4518-4527. [Abstract] [Full Text] [PDF]  

Synergy between Two Active Sites of Human Complement Receptor Type 1 (CD35) in Complement Regulation: Implications for the Structure of the Classical Pathway C3 Convertase and Generation of More Potent Inhibitors

Malgorzata Krych-Goldberg, Richard E. Hauhart, Tina Porzukowiak, and John P. Atkinson
J Immunol 2005 175: 4528-4535. [Abstract] [Full Text] [PDF]  

Functional Role of the Linker between the Complement Control Protein Modules of Complement Protease C1s

Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Christine Gaboriaud, and Gérard J. Arlaud
J Immunol 2005 175: 4536-4542. [Abstract] [Full Text] [PDF]  

Regulation of Rat Basophilic Leukemia-2H3 Mast Cell Secretion by a Constitutive Lyn Kinase Interaction with the High Affinity IgE Receptor (FcRI)

Becky M. Vonakis, Scott P. Gibbons, Jr, Masashi J. Rotté, Elizabeth A. Brothers, Seok C. Kim, Kristin Chichester, and Susan M. MacDonald
J Immunol 2005 175: 4543-4554. [Abstract] [Full Text] [PDF]  

Autoantibodies to Fibrillin-1 Activate Normal Human Fibroblasts in Culture through the TGF- Pathway to Recapitulate the "Scleroderma Phenotype"

Xiaodong Zhou, Filemon K. Tan, Dianna M. Milewicz, Xinjian Guo, Constantin A. Bona, and Frank C. Arnett
J Immunol 2005 175: 4555-4560. [Abstract] [Full Text] [PDF]  

Nonobese Diabetic Mouse Congenic Analysis Reveals Chromosome 11 Locus Contributing to Diabetes Susceptibility, Macrophage STAT5 Dysfunction, and Granulocyte-Macrophage Colony-Stimulating Factor Overproduction

Sally A. Litherland, Kristie M. Grebe, Nicole S. Belkin, Edward Paek, Jessica Elf, Mark Atkinson, Laurence Morel, Michael J. Clare-Salzler, and Marcia McDuffie
J Immunol 2005 175: 4561-4565. [Abstract] [Full Text] [PDF]  

The Nef Protein of HIV-1 Induces Loss of Cell Surface Costimulatory Molecules CD80 and CD86 in APCs

Ashutosh Chaudhry, Suman Ranjan Das, Amjad Hussain, Satyajit Mayor, Anna George, Vineeta Bal, Shahid Jameel, and Satyajit Rath
J Immunol 2005 175: 4566-4574. [Abstract] [Full Text] [PDF]  

IL-16 Is Critical for Tropheryma whipplei Replication in Whipple’s Disease

Benoît Desnues, Didier Raoult, and Jean-Louis Mege
J Immunol 2005 175: 4575-4582. [Abstract] [Full Text] [PDF]  

Tumor-Associated CD8⁺ T Cell Tolerance Induced by Bone Marrow-Derived Immature Myeloid Cells

Sergei Kusmartsev, Srinivas Nagaraj, and Dmitry I. Gabrilovich
J Immunol 2005 175: 4583-4592. [Abstract] [Full Text] [PDF]  

Increased Susceptibility of Mice Lacking T-bet to Infection with Mycobacterium tuberculosis Correlates with Increased IL-10 and Decreased IFN- Production

Brandon M. Sullivan, Ousman Jobe, Vanja Lazarevic, Kristine Vasquez, Roderick Bronson, Laurie H. Glimcher, and Igor Kramnik
J Immunol 2005 175: 4593-4602. [Abstract] [Full Text] [PDF]  

Expression of T-bet by CD4 T Cells Is Essential for Resistance to Salmonella Infection

Rajesh Ravindran, Joseph Foley, Thomas Stoklasek, Laurie H. Glimcher, and Stephen J. McSorley
J Immunol 2005 175: 4603-4610. [Abstract] [Full Text] [PDF]  

Role of NK Cell-Activating Receptors and Their Ligands in the Lysis of Mononuclear Phagocytes Infected with an Intracellular Bacterium

Ramakrishna Vankayalapati, Ankita Garg, Angel Porgador, David E. Griffith, Peter Klucar, Hassan Safi, William M. Girard, David Cosman, Thomas Spies, and Peter F. Barnes
J Immunol 2005 175: 4611-4617. [Abstract] [Full Text] [PDF]  

CD8⁺ T Cell Epitope-Flanking Mutations Disrupt Proteasomal Processing of HIV-1 Nef

Anita Milicic, David A. Price, Peter Zimbwa, Bruce L. Booth, Helen L. Brown, Philippa J. Easterbrook, Kara Olsen, Nicola Robinson, Uzi Gileadi, Andrew K. Sewell, Vincenzo Cerundolo, and Rodney E. Phillips
J Immunol 2005 175: 4618-4626. [Abstract] [Full Text] [PDF]  

A Novel Role of CD30/CD30 Ligand Signaling in the Generation of Long-Lived Memory CD8⁺ T Cells

Hitoshi Nishimura, Toshiki Yajima, Hiromi Muta, Eckhard R. Podack, Kenzaburo Tani, and Yasunobu Yoshikai
J Immunol 2005 175: 4627-4634. [Abstract] [Full Text] [PDF]  

Type I Interferons Trigger Systemic, Partial Lymphocyte Activation in Response to Viral Infection

Mohammed Alsharifi, Mario Lobigs, Matthias Regner, Eva Lee, Aulikki Koskinen, and Arno Müllbacher
J Immunol 2005 175: 4635-4640. [Abstract] [Full Text] [PDF]  

A Dipalmitoylated Lipoprotein from Mycoplasma pneumoniae Activates NF-B through TLR1, TLR2, and TLR6

Takashi Shimizu, Yutaka Kida, and Koichi Kuwano
J Immunol 2005 175: 4641-4646. [Abstract] [Full Text] [PDF]  

Bordetella Type III Secretion Modulates Dendritic Cell Migration Resulting in Immunosuppression and Bacterial Persistence

Jason A. Skinner, Mylisa R. Pilione, Hao Shen, Eric T. Harvill, and Ming H. Yuk
J Immunol 2005 175: 4647-4652. [Abstract] [Full Text] [PDF]  

Synergy between Extracellular Group IIA Phospholipase A₂ and Phagocyte NADPH Oxidase in Digestion of Phospholipids of Staphylococcus aureus Ingested by Human Neutrophils

Jon K. Femling, William M. Nauseef, and Jerrold P. Weiss
J Immunol 2005 175: 4653-4661. [Abstract] [Full Text] [PDF]  

Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37

Sho Tokumaru, Koji Sayama, Yuji Shirakata, Hitoshi Komatsuzawa, Kazuhisa Ouhara, Yasushi Hanakawa, Yoko Yahata, Xiuju Dai, Mikiko Tohyama, Hiroshi Nagai, Lujun Yang, Shigeki Higashiyama, Akihiko Yoshimura, Motoyuki Sugai, and Koji Hashimoto
J Immunol 2005 175: 4662-4668. [Abstract] [Full Text] [PDF]  

Molecular Basis of Reduced Potency of Underacylated Endotoxins

Athmane Teghanemt, DeSheng Zhang, Erika N. Levis, Jerrold P. Weiss, and Theresa L. Gioannini
J Immunol 2005 175: 4669-4676. [Abstract] [Full Text] [PDF]  

Recall Proliferation Potential of Memory CD8⁺ T Cells and Antiviral Protection

Martin F. Bachmann, Petra Wolint, Katrin Schwarz, and Annette Oxenius
J Immunol 2005 175: 4677-4685. [Abstract] [Full Text] [PDF]  

Functional Properties and Lineage Relationship of CD8⁺ T Cell Subsets Identified by Expression of IL-7 Receptor and CD62L

Martin F. Bachmann, Petra Wolint, Katrin Schwarz, Petra Jäger, and Annette Oxenius
J Immunol 2005 175: 4686-4696. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Zinc-Mediated Inhibition of Cyclic Nucleotide Phosphodiesterase Activity and Expression Suppresses TNF- and IL-1 Production in Monocytes by Elevation of Guanosine 3',5'-Cyclic Monophosphate

Verena von Bülow, Lothar Rink, and Hajo Haase
J Immunol 2005 175: 4697-4705. [Abstract] [Full Text] [PDF]  

gC1q Receptor Ligation Selectively Down-Regulates Human IL-12 Production through Activation of the Phosphoinositide 3-Kinase Pathway

Stephen N. Waggoner, Michael W. Cruise, Rachel Kassel, and Young S. Hahn
J Immunol 2005 175: 4706-4714. [Abstract] [Full Text] [PDF]  

Interactions of the Extracellular Matrix Proteoglycans Decorin and Biglycan with C1q and Collectins

Tom W. L. Groeneveld, Melinda Oroszlán, Rick T. Owens, Maria C. Faber-Krol, Astrid C. Bakker, Gérard J. Arlaud, David J. McQuillan, Uday Kishore, Mohamed R. Daha, and Anja Roos
J Immunol 2005 175: 4715-4723. [Abstract] [Full Text] [PDF]  

A Small Molecule ₄₁ Antagonist Prevents Development of Murine Lyme Arthritis without Affecting Protective Immunity

Joachim Gläsner, Horst Blum, Volkmar Wehner, Hans Ulrich Stilz, Jonathan D. Humphries, G. Paul Curley, A. Paul Mould, Martin J. Humphries, Rupert Hallmann, Martin Röllinghoff, and André Gessner
J Immunol 2005 175: 4724-4734. [Abstract] [Full Text] [PDF]  

Inflammatory Responses to Pneumovirus Infection in IFN-R Gene-Deleted Mice

Tara L. Garvey, Kimberly D. Dyer, John A. Ellis, Cynthia A. Bonville, Barbara Foster, Calman Prussin, Andrew J. Easton, Joseph B. Domachowske, and Helene F. Rosenberg
J Immunol 2005 175: 4735-4744. [Abstract] [Full Text] [PDF]  

A Novel Role of Hepatocyte Growth Factor as an Immune Regulator through Suppressing Dendritic Cell Function

Katsuhide Okunishi, Makoto Dohi, Kazuyuki Nakagome, Ryoichi Tanaka, Shinya Mizuno, Kunio Matsumoto, Jun-ichi Miyazaki, Toshikazu Nakamura, and Kazuhiko Yamamoto
J Immunol 2005 175: 4745-4753. [Abstract] [Full Text] [PDF]  

CD44 and Annexin A2 Mediate the C5a Chemotactic Cofactor Function of the Vitamin D Binding Protein

Lauren A. McVoy and Richard R. Kew
J Immunol 2005 175: 4754-4760. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Suppression of Ongoing Disease in a Nonhuman Primate Model of Multiple Sclerosis by a Human-Anti-Human IL-12p40 Antibody

Bert A. ’t Hart, Herbert P. M. Brok, Ed Remarque, Jacqueline Benson, George Treacy, Sandra Amor, Rogier Q. Hintzen, Jon D. Laman, Jan Bauer, and Erwin L. A. Blezer
J Immunol 2005 175: 4761-4768. [Abstract] [Full Text] [PDF]  

Anti-IFN- Autoantibodies in Disseminated Nontuberculous Mycobacterial Infections

Smita Y. Patel, Li Ding, Margaret R. Brown, Larry Lantz, Ted Gay, Stuart Cohen, Lenna A. Martyak, Bernard Kubak, and Steven M. Holland
J Immunol 2005 175: 4769-4776. [Abstract] [Full Text] [PDF]  

Induction of Apoptosis by the Hydrocarbon Oil Pristane: Implications for Pristane-Induced Lupus

Nicola Calvani, Roberto Caricchio, Marco Tucci, Eric S. Sobel, Franco Silvestris, Paola Tartaglia, and Hanno B. Richards
J Immunol 2005 175: 4777-4782. [Abstract] [Full Text] [PDF]  

Essential Roles of the Fas-Associated Death Domain in Autoimmune Encephalomyelitis

Jing Sun, Brendan Hilliard, Lingyun Xu, and Youhai H. Chen
J Immunol 2005 175: 4783-4788. [Abstract] [Full Text] [PDF]  

HIV-Specific CD8⁺ Lymphocytes in Semen Are Not Associated with Reduced HIV Shedding

Prameet M. Sheth, Ali Danesh, Kamnoosh Shahabi, Anuradha Rebbapragada, Colin Kovacs, Rowena Dimayuga, Roberta Halpenny, Kelly S. MacDonald, Tony Mazzulli, David Kelvin, Mario Ostrowski, and Rupert Kaul
J Immunol 2005 175: 4789-4796. [Abstract] [Full Text] [PDF]  

Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells

Virginie Vignard, Brigitte Lemercier, Annick Lim, Marie-Christine Pandolfino, Yannick Guilloux, Amir Khammari, Catherine Rabu, Klara Echasserieau, François Lang, Marie-Lise Gougeon, Brigitte Dreno, Francine Jotereau, and Nathalie Labarriere
J Immunol 2005 175: 4797-4805. [Abstract] [Full Text] [PDF]  

-Melanocyte-Stimulating Hormone Suppresses Antigen-Induced Lymphocyte Proliferation in Humans Independently of Melanocortin 1 Receptor Gene Status

Ashley Cooper, Samantha J. Robinson, Chris Pickard, Claire L. Jackson, Peter S. Friedmann, and Eugene Healy
J Immunol 2005 175: 4806-4813. [Abstract] [Full Text] [PDF]  

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