IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2005 175: 631-632. [Full Text] [PDF]  

BRIEF REVIEW:

DNA Vaccines: Progress and Challenges

John J. Donnelly, Britta Wahren, and Margaret A. Liu
J Immunol 2005 175: 633-639. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: IL-12 Induces CD4⁺CD25^– T Cell Activation in the Presence of T Regulatory Cells

Irah L. King and Benjamin M. Segal
J Immunol 2005 175: 641-645. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

E2F1 and E2F2 Are Differentially Required for Homeostasis-Driven and Antigen-Induced T Cell Proliferation In Vivo

Deborah DeRyckere and James DeGregori
J Immunol 2005 175: 647-655. [Abstract] [Full Text] [PDF]  

Active Ca²⁺/Calmodulin-Dependent Protein Kinase IIB Impairs Positive Selection of T Cells by Modulating TCR Signaling

Maureen A. McGargill, Leslie L. Sharp, Jack D. Bui, Stephen M. Hedrick, and Sébastien Calbo
J Immunol 2005 175: 656-664. [Abstract] [Full Text] [PDF]  

Mechanisms of the Antitumor Responses and Host-versus-Graft Reactions Induced by Recipient Leukocyte Infusions in Mixed Chimeras Prepared with Nonmyeloablative Conditioning: A Critical Role for Recipient CD4⁺ T Cells and Recipient Leukocyte Infusion-Derived IFN--Producing CD8⁺ T Cells

Marie-Therese Rubio, Toshiki I. Saito, Kristin Kattleman, Guiling Zhao, Jennifer Buchli, and Megan Sykes
J Immunol 2005 175: 665-676. [Abstract] [Full Text] [PDF]  

Induction of a Regulatory Phenotype in Human CD4⁺ T Cells by Streptococcal M Protein

Jeffrey D. Price, Jessica Schaumburg, Charlotta Sandin, John P. Atkinson, Gunnar Lindahl, and Claudia Kemper
J Immunol 2005 175: 677-684. [Abstract] [Full Text] [PDF]  

The Synthetic Peptide Trp-Lys-Tyr-Met-Val-D-Met Inhibits Human Monocyte-Derived Dendritic Cell Maturation via Formyl Peptide Receptor and Formyl Peptide Receptor-Like 2

Hyun Kyu Kang, Ha-Young Lee, Mi-Kyoung Kim, Kyoung Sun Park, Yeong Min Park, Jong-Young Kwak, and Yoe-Sik Bae
J Immunol 2005 175: 685-692. [Abstract] [Full Text] [PDF]  

In Vivo Hydrodynamic Delivery of cDNA Encoding IL-2: Rapid, Sustained Redistribution, Activation of Mouse NK Cells, and Therapeutic Potential in the Absence of NKT Cells

John R. Ortaldo, Robin T. Winkler-Pickett, Earl W. Bere, Jr, Morihiro Watanabe, William J. Murphy, and Robert H. Wiltrout
J Immunol 2005 175: 693-699. [Abstract] [Full Text] [PDF]  

Inefficient Cross-Presentation Limits the CD8⁺ T Cell Response to a Subdominant Tumor Antigen Epitope

Pavel Otahal, Sandra C. Hutchinson, Lawrence M. Mylin, M. Judith Tevethia, Satvir S. Tevethia, and Todd D. Schell
J Immunol 2005 175: 700-712. [Abstract] [Full Text] [PDF]  

The Type 1 Cysteinyl Leukotriene Receptor Triggers Calcium Influx and Chemotaxis in Mouse - and Effector T Cells

Immo Prinz, Claude Gregoire, Hans Mollenkopf, Enrique Aguado, Ying Wang, Marie Malissen, Stefan H.E. Kaufmann, and Bernard Malissen
J Immunol 2005 175: 713-719. [Abstract] [Full Text] [PDF]  

Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo

Katrin Wiemann, Hans-Willi Mittrücker, Ute Feger, Stefan A. Welte, Wayne M. Yokoyama, Thomas Spies, Hans-Georg Rammensee, and Alexander Steinle
J Immunol 2005 175: 720-729. [Abstract] [Full Text] [PDF]  

Bordetella pertussis Adenylate Cyclase Toxin Modulates Innate and Adaptive Immune Responses: Distinct Roles for Acylation and Enzymatic Activity in Immunomodulation and Cell Death

Aoife P. Boyd, Pádraig J. Ross, Helen Conroy, Nicola Mahon, Ed C. Lavelle, and Kingston H. G. Mills
J Immunol 2005 175: 730-738. [Abstract] [Full Text] [PDF]  

Phenotype and Homing of CD4 Tumor-Specific T Cells Is Modulated by Tumor Bulk

Fabio Benigni, Valérie S. Zimmermann, Stephanie Hugues, Stefano Caserta, Veronica Basso, Laura Rivino, Elizabeth Ingulli, Laurent Malherbe, Nicolas Glaichenhaus, and Anna Mondino
J Immunol 2005 175: 739-748. [Abstract] [Full Text] [PDF]  

Phospholipase C-2 Is a Critical Signaling Mediator for Murine NK Cell Activating Receptors

Ilaria Tassi, Rachel Presti, Sungjin Kim, Wayne M. Yokoyama, Susan Gilfillan, and Marco Colonna
J Immunol 2005 175: 749-754. [Abstract] [Full Text] [PDF]  

IL-21 Sustains CD28 Expression on IL-15-Activated Human Naive CD8⁺ T Cells

Nuno L. Alves, Fernando A. Arosa, and René A. W. van Lier
J Immunol 2005 175: 755-762. [Abstract] [Full Text] [PDF]  

Expansion and Hyperactivity of CD1d-Restricted NKT Cells during the Progression of Systemic Lupus Erythematosus in (New Zealand Black x New Zealand White)F₁ Mice

Claire Forestier, Alberto Molano, Jin Seon Im, Yves Dutronc, Betty Diamond, Anne Davidson, Petr A. Illarionov, Gurdyal S. Besra, and Steven A. Porcelli
J Immunol 2005 175: 763-770. [Abstract] [Full Text] [PDF]  

Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation

Sergio A. Quezada, Kathy Bennett, Bruce R. Blazar, Alexander Y. Rudensky, Shimon Sakaguchi, and Randolph J. Noelle
J Immunol 2005 175: 771-779. [Abstract] [Full Text] [PDF]  

Mechanisms of Gene Therapy for Tolerance: B7 Signaling Is Required for Peptide-IgG Gene-Transferred Tolerance Induction

Mary T. Litzinger, Yan Su, Tie Chi Lei, Nadejda Soukhareva, and David W. Scott
J Immunol 2005 175: 780-787. [Abstract] [Full Text] [PDF]  

IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN- Responses if IL-12p70 Is Available

Shabaana A. Khader, John E. Pearl, Kaori Sakamoto, Leigh Gilmartin, Guy K. Bell, Dawn M. Jelley-Gibbs, Nico Ghilardi, Fred deSauvage, and Andrea M. Cooper
J Immunol 2005 175: 788-795. [Abstract] [Full Text] [PDF]  

Cross-Presentation of the Long-Lived Lymphocytic Choriomeningitis Virus Nucleoprotein Does Not Require Neosynthesis and Is Enhanced via Heat Shock Proteins

Sameh Basta, Ricarda Stoessel, Michael Basler, Maries van den Broek, and Marcus Groettrup
J Immunol 2005 175: 796-805. [Abstract] [Full Text] [PDF]  

Nitric Oxide Inhibits IFN- Production of Human Plasmacytoid Dendritic Cells Partly via a Guanosine 3',5'-Cyclic Monophosphate-Dependent Pathway

Rimpei Morita, Takashi Uchiyama, and Toshiyuki Hori
J Immunol 2005 175: 806-812. [Abstract] [Full Text] [PDF]  

Cyclooxygenase 2 Inhibition Promotes IFN--Dependent Enhancement of Antitumor Responses

Sherven Sharma, Li Zhu, Seok Chul Yang, Ling Zhang, Jeff Lin, Sven Hillinger, Brian Gardner, Karen Reckamp, Robert M. Strieter, Min Huang, Raj K. Batra, and Steven M. Dubinett
J Immunol 2005 175: 813-819. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Mediated Cross-Presentation of Antigens Derived from Colon Carcinoma Cells Exposed to a Highly Cytotoxic Multidrug Regimen with Gemcitabine, Oxaliplatin, 5-Fluorouracil, and Leucovorin, Elicits a Powerful Human Antigen-Specific CTL Response with Antitumor Activity in Vitro

Pierpaolo Correale*, Maria Grazia Cusi, Maria Teresa Del Vecchio, Angelo Aquino, Salvatore Prete, Kwong Y. Tsang, Lucia Micheli, Cristina Nencini, Marco La Placa*, Francesco Montagnani*, Chiara Terrosi, Michele Caraglia, Vincenzo Formica, Giorgio Giorgi, Enzo Bonmassar, and Guido Francini*
J Immunol 2005 175: 820-828. [Abstract] [Full Text] [PDF]  

Orally Tolerized T Cells Can Form Conjugates with APCs but Are Defective in Immunological Synapse Formation

Wataru Ise, Kentaro Nakamura, Nobuko Shimizu, Hirofumi Goto, Kenichiro Fujimoto, Shuichi Kaminogawa, and Satoshi Hachimura
J Immunol 2005 175: 829-838. [Abstract] [Full Text] [PDF]  

TLR4 and Toll-IL-1 Receptor Domain-Containing Adapter-Inducing IFN-, but Not MyD88, Regulate Escherichia coli-Induced Dendritic Cell Maturation and Apoptosis In Vivo

Carl De Trez, Bernard Pajak, Maryse Brait, Nicolas Glaichenhaus, Jacques Urbain, Muriel Moser, Grégoire Lauvau, and Eric Muraille
J Immunol 2005 175: 839-846. [Abstract] [Full Text] [PDF]  

Enhanced Antibacterial Potential in UBP43-Deficient Mice against Salmonella typhimurium Infection by Up-Regulating Type I IFN Signaling

Keun Il Kim, Oxana A. Malakhova, Kasper Hoebe, Ming Yan, Bruce Beutler, and Dong-Er Zhang
J Immunol 2005 175: 847-854. [Abstract] [Full Text] [PDF]  

Antigen Presentation by an Immature Myeloid Dendritic Cell Line Does Not Cause CTL Deletion In Vivo, but Generates CD8⁺ Central Memory-Like T Cells That Can Be Rescued for Full Effector Function

Hélène Dumortier, Geertje J. D. van Mierlo, Deirdre Egan, Willem van Ewijk, René E. M. Toes, Rienk Offringa, and Cornelis J. M. Melief
J Immunol 2005 175: 855-863. [Abstract] [Full Text] [PDF]  

T Cell Leukemia-1 Modulates TCR Signal Strength and IFN- Levels through Phosphatidylinositol 3-Kinase and Protein Kinase C Pathway Activation

Katrina K. Hoyer, Marco Herling, Ksenia Bagrintseva, David W. Dawson, Samuel W. French, Mathilde Renard, Jason G. Weinger, Dan Jones, and Michael A. Teitell
J Immunol 2005 175: 864-873. [Abstract] [Full Text] [PDF]  

CCR2 and CCR6, but Not Endothelial Selectins, Mediate the Accumulation of Immature Dendritic Cells within the Lungs of Mice in Response to Particulate Antigen

John J. Osterholzer, Theresa Ames, Timothy Polak, Joanne Sonstein, Bethany B. Moore, Stephen W. Chensue, Galen B. Toews, and Jeffrey L. Curtis
J Immunol 2005 175: 874-883. [Abstract] [Full Text] [PDF]  

Regulation of Follicular Dendritic Cell Networks by Activated T Cells: The Role of CD137 Signaling

Yonglian Sun, Sarah E. Blink, Jonathan H. Chen, and Yang-Xin Fu
J Immunol 2005 175: 884-890. [Abstract] [Full Text] [PDF]  

Dendritic Cell Aggresome-Like-Induced Structure Formation and Delayed Antigen Presentation Coincide in Influenza Virus-Infected Dendritic Cells

Sylvia Herter, Philipp Osterloh, Norbert Hilf, Gerd Rechtsteiner, Jörg Höhfeld, Hans-Georg Rammensee, and Hansjörg Schild
J Immunol 2005 175: 891-898. [Abstract] [Full Text] [PDF]  

NKT Cells Are Critical for the Initiation of an Inflammatory Bowel Response against Toxoplasma gondii

Catherine Ronet, Sylvie Darche, Maria Leite de Moraes, Sachiko Miyake, Takashi Yamamura, Jacques A. Louis, Lloyd H. Kasper, and Dominique Buzoni-Gatel
J Immunol 2005 175: 899-908. [Abstract] [Full Text] [PDF]  

In Vivo Assessment of the Relative Contributions of Deletion, Anergy, and Editing to B Cell Self-Tolerance

Keli L. Hippen, Brian R. Schram, Lina E. Tze, Kathryn A. Pape, Marc K. Jenkins, and Timothy W. Behrens
J Immunol 2005 175: 909-916. [Abstract] [Full Text] [PDF]  

IL-4 Inhibits Bone-Resorbing Activity of Mature Osteoclasts by Affecting NF-B and Ca²⁺ Signaling

Latha S. Mangashetti, Shruti M. Khapli, and Mohan R. Wani
J Immunol 2005 175: 917-925. [Abstract] [Full Text] [PDF]  

Regulation of LFA-1 Activity through Cytoskeleton Remodeling and Signaling Components Modulates the Efficiency of HIV Type-1 Entry in Activated CD4⁺ T Lymphocytes

Mélanie R. Tardif and Michel J. Tremblay
J Immunol 2005 175: 926-935. [Abstract] [Full Text] [PDF]  

Genetic Dissection of the Murine Lupus Susceptibility Locus Sle2: Contributions to Increased Peritoneal B-1a Cells and Lupus Nephritis Map to Different Loci

Zhiwei Xu, Biyan Duan, Byron P. Croker, Edward K. Wakeland, and Laurence Morel
J Immunol 2005 175: 936-943. [Abstract] [Full Text] [PDF]  

Failure of CD25⁺ T Cells from Lupus-Prone Mice to Suppress Lupus Glomerulonephritis and Sialoadenitis

Harini Bagavant and Kenneth S. K. Tung
J Immunol 2005 175: 944-950. [Abstract] [Full Text] [PDF]  

Restraint of B Cell Activation by Foxj1-Mediated Antagonism of NF-B and IL-6

Ling Lin, Steven L. Brody, and Stanford L. Peng
J Immunol 2005 175: 951-958. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide Injection Induces Relapses of Experimental Autoimmune Encephalomyelitis in Nontransgenic Mice via Bystander Activation of Autoreactive CD4⁺ Cells

Axel Nogai, Volker Siffrin, Kerstin Bonhagen, Caspar F. Pfueller, Thordis Hohnstein, Rudolf Volkmer-Engert, Wolfgang Brück, Christine Stadelmann, and Thomas Kamradt
J Immunol 2005 175: 959-966. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Calnexin and ERp57 Facilitate the Assembly of the Neonatal Fc Receptor for IgG with ₂-Microglobulin in the Endoplasmic Reticulum

Xiaoping Zhu, Junmin Peng, Daohong Chen, Xindong Liu, Lilin Ye, Hideki Iijima, Kumar Kadavil, Wayne I. Lencer, and Richard S. Blumberg
J Immunol 2005 175: 967-976. [Abstract] [Full Text] [PDF]  

Crystal Structure of Mouse CD1d Bound to the Self Ligand Phosphatidylcholine: A Molecular Basis for NKT Cell Activation

Barbara Giabbai, Stèphane Sidobre, M. D. Max Crispin, Yovan Sanchez-Ruìz, Angela Bachi, Mitchell Kronenberg, Ian A. Wilson, and Massimo Degano
J Immunol 2005 175: 977-984. [Abstract] [Full Text] [PDF]  

Effects of Bcl-2 Levels on Fas Signaling-Induced Caspase-3 Activation: Molecular Genetic Tests of Computational Model Predictions

Fei Hua, Melanie G. Cornejo, Michael H. Cardone, Cynthia L. Stokes, and Douglas A. Lauffenburger
J Immunol 2005 175: 985-995. [Abstract] [Full Text] [PDF]  

Hierarchical Regulation of CTLA-4 Dimer-Based Lattice Formation and Its Biological Relevance for T Cell Inactivation

Peter J. Darlington, Mark G. Kirchhof, Gabriel Criado, Jitin Sondhi, and Joaquín Madrenas
J Immunol 2005 175: 996-1004. [Abstract] [Full Text] [PDF]  

Mutational Analysis of the Human 2B4 (CD244)/CD48 Interaction: Lys⁶⁸ and Glu⁷⁰ in the V Domain of 2B4 Are Critical for CD48 Binding and Functional Activation of NK Cells

Stephen O. Mathew, Pappanaicken R. Kumaresan, Jae Kyung Lee, Van T. Huynh, and Porunelloor A. Mathew
J Immunol 2005 175: 1005-1013. [Abstract] [Full Text] [PDF]  

Critical Role of the Fifth Domain of E-Cadherin for Heterophilic Adhesion with _E7, But Not for Homophilic Adhesion

Kiyono Shiraishi, Kensei Tsuzaka, Keiko Yoshimoto, Chika Kumazawa, Kyoko Nozaki, Tohru Abe, Kazuo Tsubota, and Tsutomu Takeuchi
J Immunol 2005 175: 1014-1021. [Abstract] [Full Text] [PDF]  

Transcriptional Regulation of CD1D1 by Ets Family Transcription Factors

Yanbiao Geng, Peter Laslo, Kevin Barton, and Chyung-Ru Wang
J Immunol 2005 175: 1022-1029. [Abstract] [Full Text] [PDF]  

X Box-Like Sequences in the MHC Class II Region Maintain Regulatory Function

Jorge A. Gomez, Parimal Majumder, Uma M. Nagarajan, and Jeremy M. Boss
J Immunol 2005 175: 1030-1040. [Abstract] [Full Text] [PDF]  

Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus

Margarida Saraiva¶, Jillian R. Christensen, Alla V. Tsytsykova, Anne E. Goldfeld, Steven C. Ley, Dimitris Kioussis, and Anne O'Garra
J Immunol 2005 175: 1041-1046. [Abstract] [Full Text] [PDF]  

Hepatocytes Express Abundant Surface Class I MHC and Efficiently Use Transporter Associated with Antigen Processing, Tapasin, and Low Molecular Weight Polypeptide Proteasome Subunit Components of Antigen Processing and Presentation Pathway

Ming Chen, Piotr Tabaczewski, Steven M. Truscott, Luc Van Kaer, and Iwona Stroynowski
J Immunol 2005 175: 1047-1055. [Abstract] [Full Text] [PDF]  

A Critical Role for Sialylation in Cryoglobulin Activity of Murine IgG3 Monoclonal Antibodies

Yasuhiro Kuroda, Aki Kuroki, Shuichi Kikuchi, Takaaki Funase, Munehiro Nakata, and Shozo Izui
J Immunol 2005 175: 1056-1061. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Epistatic Suppression of Systemic Lupus Erythematosus: Fine Mapping of Sles1 to Less Than 1 Mb

Srividya Subramanian, Young-Sun Yim, Kui Liu, Katalin Tus, Xin J. Zhou, and Edward K. Wakeland
J Immunol 2005 175: 1062-1072. [Abstract] [Full Text] [PDF]  

Multiple Germline Light Chains Generate Anti-Insulin B Cells in Nonobese Diabetic Mice

Emily J. Woodward and James W. Thomas
J Immunol 2005 175: 1073-1079. [Abstract] [Full Text] [PDF]  

Several Genes Contribute to the Production of Autoreactive B and T Cells in the Murine Lupus Susceptibility Locus Sle1c

Yifang Chen, Daniel Perry, Susan A. Boackle, Eric S. Sobel, Hector Molina, Byron P. Croker, and Laurence Morel
J Immunol 2005 175: 1080-1089. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Reduced Three-Dimensional Motility in Dehydrated Airway Mucus Prevents Neutrophil Capture and Killing Bacteria on Airway Epithelial Surfaces

Hirotoshi Matsui, Margrith W. Verghese, Mehmet Kesimer, Ute E. Schwab, Scott H. Randell, John K. Sheehan, Barbara R. Grubb, and Richard C. Boucher
J Immunol 2005 175: 1090-1099. [Abstract] [Full Text] [PDF]  

Critical Role for the Oligoadenylate Synthetase/RNase L Pathway in Response to IFN- during Acute Ocular Herpes Simplex Virus Type 1 Infection

Bobbie Ann Austin, Cassandra James, Robert H. Silverman, and Daniel J. J. Carr
J Immunol 2005 175: 1100-1106. [Abstract] [Full Text] [PDF]  

Long-Term Control of Mycobacterium tuberculosis Infection Is Mediated by Dynamic Immune Responses

Vanja Lazarevic, Dawn Nolt, and JoAnne L. Flynn
J Immunol 2005 175: 1107-1117. [Abstract] [Full Text] [PDF]  

Lentivirus Infection Causes Neuroinflammation and Neuronal Injury in Dorsal Root Ganglia: Pathogenic Effects of STAT-1 and Inducible Nitric Oxide Synthase

Yu Zhu, Gareth Jones, Shigeki Tsutsui, Wycliffe Opii, Shuhong Liu, Claudia Silva, D. Allan Butterfield, and Christopher Power
J Immunol 2005 175: 1118-1126. [Abstract] [Full Text] [PDF]  

Developmentally Regulated Intestinal Expression of IFN- and Its Target Genes and the Age-Specific Response to Enteric Salmonella Infection

Sue J. Rhee, W. Allan Walker, and Bobby J. Cherayil
J Immunol 2005 175: 1127-1136. [Abstract] [Full Text] [PDF]  

Invariant V14⁺ NKT Cells Participate in the Early Response to Enteric Listeria monocytogenes Infection

Thomas Ranson, Søren Bregenholt, Agnes Lehuen, Olivier Gaillot, Maria C. Leite-de-Moraes, André Herbelin, Patrick Berche, and James P. Di Santo
J Immunol 2005 175: 1137-1144. [Abstract] [Full Text] [PDF]  

Human Rhinoviruses Inhibit the Accessory Function of Dendritic Cells by Inducing Sialoadhesin and B7-H1 Expression

Stefanie Kirchberger, Otto Majdic, Peter Steinberger, Stefan Blüml, Katharina Pfistershammer, Gerhard Zlabinger, Luiza Deszcz, Ernst Kuechler, Walter Knapp, and Johannes Stöckl
J Immunol 2005 175: 1145-1152. [Abstract] [Full Text] [PDF]  

Immunoproteasome-Deficient Mice Mount Largely Normal CD8⁺ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination

Alexander K. Nussbaum, Maria P. Rodriguez-Carreno, Nicola Benning, Jason Botten, and J. Lindsay Whitton
J Immunol 2005 175: 1153-1160. [Abstract] [Full Text] [PDF]  

18-Glycyrrhetinic Acid Triggers Curative Th1 Response and Nitric Oxide Up-Regulation in Experimental Visceral Leishmaniasis Associated with the Activation of NF-B

Anindita Ukil, Aruna Biswas, Tapasi Das, and Pijush K. Das
J Immunol 2005 175: 1161-1169. [Abstract] [Full Text] [PDF]  

Diminished Expression and Function of TLR in Lymphatic Filariasis: A Novel Mechanism of Immune Dysregulation

Subash Babu, Carla P. Blauvelt, V. Kumaraswami, and Thomas B. Nutman
J Immunol 2005 175: 1170-1176. [Abstract] [Full Text] [PDF]  

Priming Effect of Lipopolysaccharide on Acetyl-Coenzyme A:Lyso-Platelet-Activating Factor Acetyltransferase Is MyD88 and TRIF Independent

Hideo Shindou, Satoshi Ishii, Masahiro Yamamoto, Kiyoshi Takeda, Shizuo Akira, and Takao Shimizu
J Immunol 2005 175: 1177-1183. [Abstract] [Full Text] [PDF]  

Induction of Humoral and CD8⁺ T Cell Responses Are Required for Protection against Lethal Ebola Virus Infection

Kelly L. Warfield, Gene Olinger, Emily M. Deal, Dana L. Swenson, Michael Bailey, Diane L. Negley, Mary Kate Hart, and Sina Bavari
J Immunol 2005 175: 1184-1191. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

An Intact Phosphocholine Binding Site Is Necessary for Transgenic Rabbit C-Reactive Protein to Protect Mice against Challenge with Platelet-Activating Factor

Steven Black, Augusta Wilson, and David Samols
J Immunol 2005 175: 1192-1196. [Abstract] [Full Text] [PDF]  

Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-B and JNK

Thorsten Hagemann, Julia Wilson, Hagen Kulbe, Ningfeng Fiona Li, David A. Leinster, Kellie Charles, Florian Klemm, Tobias Pukrop, Claudia Binder, and Frances R. Balkwill
J Immunol 2005 175: 1197-1205. [Abstract] [Full Text] [PDF]  

Alterations in Nitric Oxide and Cytokine Production with Airway Inflammation in the Absence of IL-10

Bill T. Ameredes, Ruben Zamora, Jigme M. Sethi, He-Liang Liu, Lauryn K. Kohut, Amber L. Gligonic, Augustine M. K. Choi, and William J. Calhoun
J Immunol 2005 175: 1206-1213. [Abstract] [Full Text] [PDF]  

Influence of ₁ Integrin Intracytoplasmic Domains in the Regulation of VLA-4-Mediated Adhesion of Human T Cells to VCAM-1 under Flow Conditions

Maria Alessandra Rosenthal-Allieri, Michel Ticchioni, Jean Philippe Breittmayer, Yoji Shimizu, and Alain Bernard
J Immunol 2005 175: 1214-1223. [Abstract] [Full Text] [PDF]  

Anti-Vascular Endothelial Growth Factor Gene Therapy Attenuates Lung Injury and Fibrosis in Mice

Naoki Hamada, Kazuyoshi Kuwano, Mizuho Yamada, Naoki Hagimoto, Kenichi Hiasa, Kensuke Egashira, Nobutaka Nakashima, Takashige Maeyama, Michihiro Yoshimi, and Yoichi Nakanishi
J Immunol 2005 175: 1224-1231. [Abstract] [Full Text] [PDF]  

Elimination of Senescent Neutrophils by TNF-Related Apotosis-Inducing Ligand

Julian J. Lum, Gary Bren, Rebecca McClure, and Andrew D. Badley
J Immunol 2005 175: 1232-1238. [Abstract] [Full Text] [PDF]  

CD93 Is Rapidly Shed from the Surface of Human Myeloid Cells and the Soluble Form Is Detected in Human Plasma

Suzanne S. Bohlson, Richard Silva, Maria I. Fonseca, and Andrea J. Tenner
J Immunol 2005 175: 1239-1247. [Abstract] [Full Text] [PDF]  

Mechanisms Underlying Resistance of Pancreatic Islets from ALR/Lt Mice to Cytokine-Induced Destruction

Clayton E. Mathews, Wilma L. Suarez-Pinzon, Jeffrey J. Baust, Ken Strynadka, Edward H. Leiter, and Alex Rabinovitch
J Immunol 2005 175: 1248-1256. [Abstract] [Full Text] [PDF]  

A Non-Glycosaminoglycan-Binding Variant of CC Chemokine Ligand 7 (Monocyte Chemoattractant Protein-3) Antagonizes Chemokine-Mediated Inflammation

Simi Ali, Helen Robertson, Julie H. Wain, John D. Isaacs, Ghada Malik, and John A. Kirby
J Immunol 2005 175: 1257-1266. [Abstract] [Full Text] [PDF]  

P-Selectin Glycoprotein Ligand 1 Is Not Required for the Development of Experimental Autoimmune Encephalomyelitis in SJL and C57BL/6 Mice

Britta Engelhardt, Birgit Kempe, Stephanie Merfeld-Clauss, Melanie Laschinger, Bruce Furie, Martin K. Wild, and Dietmar Vestweber
J Immunol 2005 175: 1267-1275. [Abstract] [Full Text] [PDF]  

Mucosal B Cell Deficiency in IgA^–/– Mice Abrogates the Development of Allergic Lung Inflammation

Paul M. Arnaboldi, Melissa J. Behr, and Dennis W. Metzger
J Immunol 2005 175: 1276-1285. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Hom s 4, an IgE-Reactive Autoantigen Belonging to a New Subfamily of Calcium-Binding Proteins, Can Induce Th Cell Type 1-Mediated Autoreactivity

Karl J. Aichberger, Irene Mittermann, Renate Reininger, Susanne Seiberler, Ines Swoboda, Susanne Spitzauer, Tamara Kopp, Georg Stingl, Wolfgang R. Sperr, Peter Valent, Andreas Repa, Barbara Bohle, Dietrich Kraft, and Rudolf Valenta
J Immunol 2005 175: 1286-1294. [Abstract] [Full Text] [PDF]  

Contribution of the Lymphotoxin Receptor to Liver Regeneration

Robert A. Anders, Sumit K. Subudhi, Jing Wang, Klaus Pfeffer, and Yang-Xin Fu
J Immunol 2005 175: 1295-1300. [Abstract] [Full Text] [PDF]  

Targeting Positive Regulatory Domain I-Binding Factor 1 and X Box-Binding Protein 1 Transcription Factors by Multiple Myeloma-Reactive CTL

Carina Lotz, Sarah Abdel Mutallib, Nicole Oehlrich, Ulrike Liewer, Edite Antunes Ferreira, Marion Moos, Michael Hundemer, Sandra Schneider, Susanne Strand, Christoph Huber, Hartmut Goldschmidt, and Matthias Theobald
J Immunol 2005 175: 1301-1309. [Abstract] [Full Text] [PDF]  

IL-1 Induces IL-6 Expression in Human Orbital Fibroblasts: Identification of an Anatomic-Site Specific Phenotypic Attribute Relevant to Thyroid-Associated Ophthalmopathy

Beiling Chen, Shanli Tsui, and Terry J. Smith
J Immunol 2005 175: 1310-1319. [Abstract] [Full Text] [PDF]  

Host-Residual Invariant NK T Cells Attenuate Graft-versus-Host Immunity

Kyoko Haraguchi, Tsuyoshi Takahashi, Akihiko Matsumoto, Takashi Asai, Yoshinobu Kanda, Mineo Kurokawa, Seishi Ogawa, Hideaki Oda, Masaru Taniguchi, Hisamaru Hirai, and Shigeru Chiba
J Immunol 2005 175: 1320-1328. [Abstract] [Full Text] [PDF]  

Genotype-Proteotype Linkage in the Wiskott-Aldrich Syndrome

Maxim I. Lutskiy, Fred S. Rosen, and Eileen Remold-O’Donnell
J Immunol 2005 175: 1329-1336. [Abstract] [Full Text] [PDF]  

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