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Contents: Volume 175 / No. 11 / December 1, 2005   [Index by Author] 
       IN THIS ISSUE
       PILLARS OF IMMUNOLOGY
       BRIEF REVIEWS
       CUTTING EDGE
       CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
       MOLECULAR AND STRUCTURAL IMMUNOLOGY
       HOST DEFENSE
       INFLAMMATION
       CLINICAL IMMUNOLOGY
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IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2005 175: 7065-7066. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Shaping the T Cell Repertoire
Harald von Boehmer
J Immunol 2005 175: 7067-7068. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: The Major Histocompatibility Complex Determines Susceptibility to Cytotoxic T Cells Directed against Minor Histocompatibility Antigens. J. Exp. Med. 1975. 142: 1349–1364.
Michael John Bevan
J Immunol 2005 175: 7069-7084. [PDF]  

BRIEF REVIEWS:

Granulocyte Colony-Stimulating Factor: A Novel Mediator of T Cell Tolerance
Sergio Rutella, Flora Zavala, Silvio Danese, Hassen Kared, and Giuseppe Leone
J Immunol 2005 175: 7085-7091. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: CD8+CD122+ Regulatory T Cells Produce IL-10 to Suppress IFN-{gamma} Production and Proliferation of CD8+ T Cells
Agustina Tri Endharti, Muhaimin Rifa’, I, Zhe Shi, Yukari Fukuoka, Yoshio Nakahara, Yoshiyuki Kawamoto, Kozue Takeda, Ken-ichi Isobe, and Haruhiko Suzuki
J Immunol 2005 175: 7093-7097. [Abstract] [Full Text] [PDF]  

Cutting Edge: Murine CD59a Modulates Antiviral CD4+ T Cell Activity in a Complement-Independent Manner
M. Paula Longhi, Baalasubramanian Sivasankar, Nader Omidvar, B. Paul Morgan, and Awen Gallimore
J Immunol 2005 175: 7098-7102. [Abstract] [Full Text] [PDF]  

Cutting Edge: The Development of IL-4-Producing B Cells (B Effector 2 Cells) Is Controlled by IL-4, IL-4 Receptor {alpha}, and Th2 Cells
David P. Harris, Stephen Goodrich, Katja Mohrs, Markus Mohrs, and Frances E. Lund
J Immunol 2005 175: 7103-7107. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

CXCR5-Dependent Seeding of Follicular Niches by B and Th Cells Augments Antiviral B Cell Responses
Tobias Junt, Katja Fink, Reinhold Förster, Beatrice Senn, Martin Lipp, Masamichi Muramatsu, Rolf M. Zinkernagel, Burkhard Ludewig, and Hans Hengartner
J Immunol 2005 175: 7109-7116. [Abstract] [Full Text] [PDF]  

Modulation of Ovalbumin-Induced Airway Inflammation and Hyperreactivity by Tolerogenic APC
Jie Zhang-Hoover, Patricia Finn, and Joan Stein-Streilein
J Immunol 2005 175: 7117-7124. [Abstract] [Full Text] [PDF]  

B Cells Productively Engage Soluble Antigen-Pulsed Dendritic Cells: Visualization of Live-Cell Dynamics of B Cell-Dendritic Cell Interactions
Ning-Na Huang, Sang-Bae Han, Il-Young Hwang, and John H. Kehrl
J Immunol 2005 175: 7125-7134. [Abstract] [Full Text] [PDF] Data Supplement  

CD4+CD25+ T Cells Prevent the Development of Organ-Specific Autoimmune Disease by Inhibiting the Differentiation of Autoreactive Effector T Cells
Richard J. DiPaolo, Deborah D. Glass, Karen E. Bijwaard, and Ethan M. Shevach
J Immunol 2005 175: 7135-7142. [Abstract] [Full Text] [PDF]  

STAT4 Expression in Human T Cells Is Regulated by DNA Methylation but Not by Promoter Polymorphism
Hyun-Jin Shin, Hye-Young Park, Sook-Jung Jeong, Heung-Woo Park, Yoon-Keun Kim, Sang-Heon Cho, You-Young Kim, Mi-La Cho, Ho-Youn Kim, Kyung-Up Min, and Chang-Woo Lee
J Immunol 2005 175: 7143-7150. [Abstract] [Full Text] [PDF]  

Sphingosine-1-Phosphate Agonists Increase Macrophage Homing, Lymphocyte Contacts, and Endothelial Junctional Complex Formation in Murine Lymph Nodes
Irwin I. Singer, Min Tian, L. Alexandra Wickham, Jeffrey Lin, Scaria S. Matheravidathu, Michael J. Forrest, Suzanne Mandala, and Elizabeth J. Quackenbush
J Immunol 2005 175: 7151-7161. [Abstract] [Full Text] [PDF]  

Helicobacter pylori Activates NF-{kappa}B via the Alternative Pathway in B Lymphocytes
Tomoya Ohmae, Yoshihiro Hirata, Shin Maeda, Wataru Shibata, Ayako Yanai, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, and Masao Omata
J Immunol 2005 175: 7162-7169. [Abstract] [Full Text] [PDF]  

An Hour after Immunization Peritoneal B-1 Cells Are Activated to Migrate to Lymphoid Organs Where within 1 Day They Produce IgM Antibodies That Initiate Elicitation of Contact Sensitivity
Atsuko Itakura, Marian Szczepanik, Regis A. Campos, Vipin Paliwal, Monika Majewska, Hiroshi Matsuda, Kiyoshi Takatsu, and Philip W. Askenase
J Immunol 2005 175: 7170-7178. [Abstract] [Full Text] [PDF]  

RasGRP1 and RasGRP3 Regulate B Cell Proliferation by Facilitating B Cell Receptor-Ras Signaling
Jason J. Coughlin, Stacey L. Stang, Nancy A. Dower, and James C. Stone
J Immunol 2005 175: 7179-7184. [Abstract] [Full Text] [PDF]  

Membranous Glomerulonephritis Development with Th2-Type Immune Deviations in MRL/lpr Mice Deficient for IL-27 Receptor (WSX-1)
Sakiko Shimizu, Naonobu Sugiyama, Kohsuke Masutani, Atsushi Sadanaga, Yoshiyuki Miyazaki, Yasushi Inoue, Mitsuteru Akahoshi, Ritsuko Katafuchi, Hideki Hirakata, Mine Harada, Shinjiro Hamano, Hitoshi Nakashima, and Hiroki Yoshida
J Immunol 2005 175: 7185-7192. [Abstract] [Full Text] [PDF]  

Interaction of Fas Ligand and Fas Expressed on Osteoclast Precursors Increases Osteoclastogenesis
Hyewon Park, Youn-Kwan Jung, Ok-Jin Park, Yeon Ju Lee, Je-Yong Choi, and Youngnim Choi
J Immunol 2005 175: 7193-7201. [Abstract] [Full Text] [PDF]  

Glucosamine Abrogates the Acute Phase of Experimental Autoimmune Encephalomyelitis by Induction of Th2 Response
Guang-Xian Zhang, Shuo Yu, Bruno Gran, and Abdolmohamad Rostami
J Immunol 2005 175: 7202-7208. [Abstract] [Full Text] [PDF]  

Identification of the Immunodominant HY H2-Dk Epitope and Evaluation of the Role of Direct and Indirect Antigen Presentation in HY Responses
Maggie Millrain, Diane Scott, Caroline Addey, Hamlata Dewchand, Pamela Ellis, Ingrid Ehrmann, Michael Mitchell, Paul Burgoyne, Elizabeth Simpson, and Julian Dyson
J Immunol 2005 175: 7209-7217. [Abstract] [Full Text] [PDF]  

A Role for Double-Stranded RNA-Activated Protein Kinase PKR in Mycobacterium-Induced Cytokine Expression
Benny K. W. Cheung, Davy C. W. Lee, James C. B. Li, Yu-Lung Lau, and Allan S. Y. Lau
J Immunol 2005 175: 7218-7225. [Abstract] [Full Text] [PDF]  

Primary Human T Lymphocytes Engineered with a Codon-Optimized IL-15 Gene Resist Cytokine Withdrawal-Induced Apoptosis and Persist Long-Term in the Absence of Exogenous Cytokine
Cary Hsu, Marybeth S. Hughes, Zhili Zheng, Regina B. Bray, Steven A. Rosenberg, and Richard A. Morgan
J Immunol 2005 175: 7226-7234. [Abstract] [Full Text] [PDF]  

Analysis of Anthrax and Plague Biowarfare Vaccine Interactions with Human Monocyte-Derived Dendritic Cells
Anna Skowera, Esther C. de Jong, Joost H. N. Schuitemaker, Jennifer S. Allen, Simon C. Wessely, Gareth Griffiths, Martien Kapsenberg, and Mark Peakman
J Immunol 2005 175: 7235-7243. [Abstract] [Full Text] [PDF]  

Apoptosis of Antigen-Specific T Lymphocytes upon the Engagement of CD8 by Soluble HLA Class I Molecules Is Fas Ligand/Fas Mediated: Evidence for the Involvement of p56lck, Calcium Calmodulin Kinase II, and Calcium-Independent Protein Kinase C Signaling Pathways and for NF-{kappa}B and NF-AT Nuclear Translocation
Paola Contini, Massimo Ghio, Andrea Merlo, Alessandro Poggi, Francesco Indiveri, and Francesco Puppo
J Immunol 2005 175: 7244-7254. [Abstract] [Full Text] [PDF]  

The Inhibition of Autoreactive T Cell Functions by a Peptide Based on the CDR1 of an Anti-DNA Autoantibody Is via TGF-{beta}-Mediated Suppression of LFA-1 and CD44 Expression and Function
Uri Sela, Nora Mauermann, Rami Hershkoviz, Heidy Zinger, Molly Dayan, Liora Cahalon, Jian Ping Liu, Edna Mozes, and Ofer Lider
J Immunol 2005 175: 7255-7263. [Abstract] [Full Text] [PDF]  

Anti-CD25 Antibody Enhancement of Vaccine-Induced Immunogenicity: Increased Durable Cellular Immunity with Reduced Immunodominance
Anne C. Moore, Awen Gallimore, Simon J. Draper, Katherine R. Watkins, Sarah C. Gilbert, and Adrian V. S. Hill
J Immunol 2005 175: 7264-7273. [Abstract] [Full Text] [PDF]  

Early Kinetic Window of Target T Cell Susceptibility to CD25+ Regulatory T Cell Activity
Dorothy K. Sojka, Angela Hughson, Teresa L. Sukiennicki, and Deborah J. Fowell
J Immunol 2005 175: 7274-7280. [Abstract] [Full Text] [PDF]  

Plasmacytoid Dendritic Cells of Different Origins Have Distinct Characteristics and Function: Studies of Lymphoid Progenitors versus Myeloid Progenitors
Guo-Xiang Yang, Zhe-Xiong Lian, Kentaro Kikuchi, Yuki Moritoki, Aftab A. Ansari, Yong-Jun Liu, Susumu Ikehara, and M. Eric Gershwin
J Immunol 2005 175: 7281-7287. [Abstract] [Full Text] [PDF]  

Cooperation between 4-1BB and ICOS in the Immune Response to Influenza Virus Revealed by Studies of CD28/ICOS-Deficient Mice
Mariana Vidric, Woong-Kyung Suh, Umberto Dianzani, Tak W. Mak, and Tania H. Watts
J Immunol 2005 175: 7288-7296. [Abstract] [Full Text] [PDF]  

A Novel Mucosal Vaccine Based on Live Lactococci Expressing E7 Antigen and IL-12 Induces Systemic and Mucosal Immune Responses and Protects Mice against Human Papillomavirus Type 16-Induced Tumors
Luis G. Bermúdez-Humarán, Naima G. Cortes-Perez, François Lefèvre, Valeria Guimarães, Sylvie Rabot, Juan M. Alcocer-Gonzalez, Jean-Jacques Gratadoux, Cristina Rodriguez-Padilla, Reyes S. Tamez-Guerra, Gérard Corthier, Alexandra Gruss, and Philippe Langella
J Immunol 2005 175: 7297-7302. [Abstract] [Full Text] [PDF]  

Targeted Expression of Human CD1d in Transgenic Mice Reveals Independent Roles for Thymocytes and Thymic APCs in Positive and Negative Selection of V{alpha}14i NKT Cells
Jens Schümann, Paola Pittoni, Elena Tonti, H. Robson MacDonald, Paolo Dellabona, and Giulia Casorati
J Immunol 2005 175: 7303-7310. [Abstract] [Full Text] [PDF]  

The Neuropeptide Vasoactive Intestinal Peptide Generates Tolerogenic Dendritic Cells
Mario Delgado, Elena Gonzalez-Rey, and Doina Ganea
J Immunol 2005 175: 7311-7324. [Abstract] [Full Text] [PDF]  

Murine and Human IL-7 Activate STAT5 and Induce Proliferation of Normal Human Pro-B Cells
Sonja E. Johnson, Nisha Shah, Angela Panoskaltsis-Mortari, and Tucker W. LeBien
J Immunol 2005 175: 7325-7331. [Abstract] [Full Text] [PDF]  

Bone Marrow-Derived Dendritic Cells Reverse the Anergic State of CD4+CD25+ T Cells without Reversing Their Suppressive Function
Carine Brinster and Ethan M. Shevach
J Immunol 2005 175: 7332-7340. [Abstract] [Full Text] [PDF]  

The ICOS Molecule Plays a Crucial Role in the Development of Mucosal Tolerance
Katsuichi Miyamoto, Cherry I. Kingsley, Xingmin Zhang, Claudia Jabs, Leonid Izikson, Raymond A. Sobel, Howard L. Weiner, Vijay K. Kuchroo, and Arlene H. Sharpe
J Immunol 2005 175: 7341-7347. [Abstract] [Full Text] [PDF]  

Effects of Aryl Hydrocarbon Receptor Signaling on the Modulation of Th1/Th2 Balance
Takaaki Negishi, Yutaka Kato, Osamu Ooneda, Junsei Mimura, Tomonari Takada, Hidenori Mochizuki, Masayuki Yamamoto, Yoshiaki Fujii-Kuriyama, and Shoji Furusako
J Immunol 2005 175: 7348-7356. [Abstract] [Full Text] [PDF]  

Human White Blood Cells Synthesize Morphine: CYP2D6 Modulation
Wei Zhu, Patrick Cadet, Geert Baggerman, Kirk J. Mantione, and George B. Stefano
J Immunol 2005 175: 7357-7362. [Abstract] [Full Text] [PDF]  

Aberrant IgM Signaling Promotes Survival of Transitional T1 B Cells and Prevents Tolerance Induction in Lupus-Prone New Zealand Black Mice
Valerie Roy, Nan-Hua Chang, Yongchun Cai, Gabriel Bonventi, and Joan Wither
J Immunol 2005 175: 7363-7371. [Abstract] [Full Text] [PDF]  

Programmed Death-1 (PD-1):PD-Ligand 1 Interactions Inhibit TCR-Mediated Positive Selection of Thymocytes
Mary E. Keir, Yvette E. Latchman, Gordon J. Freeman, and Arlene H. Sharpe
J Immunol 2005 175: 7372-7379. [Abstract] [Full Text] [PDF]  

Respiratory Tolerance Is Inhibited by the Administration of Corticosteroids
Philippe Stock, Omid Akbari, Rosemarie H. DeKruyff, and Dale T. Umetsu
J Immunol 2005 175: 7380-7387. [Abstract] [Full Text] [PDF]  

CD8 T Cell Sensory Adaptation Dependent on TCR Avidity for Self-Antigens
Maria-Elena Marquez, Wilfried Ellmeier, Vanesa Sanchez-Guajardo, Antonio A. Freitas, Oreste Acuto, and Vincenzo Di Bartolo
J Immunol 2005 175: 7388-7397. [Abstract] [Full Text] [PDF]  

Short-Interfering RNA-Mediated Lck Knockdown Results in Augmented Downstream T Cell Responses
Trond Methi, Jacob Ngai, Milada Mahic, Mohammed Amarzguioui, Torkel Vang, and Kjetil Tasken
J Immunol 2005 175: 7398-7406. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

A Distal Regulatory Region Is Required for Constitutive and IFN-{beta}-Induced Expression of Murine TLR9 Gene
Zhu Guo, Sanjay Garg, Karen M. Hill, Lakshmi Jayashankar, Myesha R. Mooney, Mary Hoelscher, Jacqueline M. Katz, Jeremy M. Boss, and Suryaprakash Sambhara
J Immunol 2005 175: 7407-7418. [Abstract] [Full Text] [PDF]  

Stat1-Dependent Synergistic Activation of T-bet for IgG2a Production during Early Stage of B Cell Activation
Weifeng Xu and J. Jillian Zhang
J Immunol 2005 175: 7419-7424. [Abstract] [Full Text] [PDF]  

Developmental Changes in the Human Heavy Chain CDR3
M. Margarida Souto-Carneiro, Gary P. Sims, Hermann Girschik, Jisoo Lee, and Peter E. Lipsky
J Immunol 2005 175: 7425-7436. [Abstract] [Full Text] [PDF]  

Distal Enhancer Elements Transcribe Intergenic RNA in the IL-10 Family Gene Cluster
Elizabeth A. Jones and Richard A. Flavell
J Immunol 2005 175: 7437-7446. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Multiple TLRs Are Expressed in Human Cholangiocytes and Mediate Host Epithelial Defense Responses to Cryptosporidium parvum via Activation of NF-{kappa}B
Xian-Ming Chen, Steven P. O’Hara, Jeremy B. Nelson, Patrick L. Splinter, Aaron J. Small, Pamela S. Tietz, Andrew H. Limper, and Nicholas F. LaRusso
J Immunol 2005 175: 7447-7456. [Abstract] [Full Text] [PDF]  

Human Cytomegalovirus Encodes an MHC Class I-Like Molecule (UL142) That Functions to Inhibit NK Cell Lysis
Mark R. Wills, Omodele Ashiru, Matthew B. Reeves, Georgina Okecha, John Trowsdale, Peter Tomasec, Gavin W. G. Wilkinson, John Sinclair, and J. G. Patrick Sissons
J Immunol 2005 175: 7457-7465. [Abstract] [Full Text] [PDF]  

Heterogeneous Human NK Cell Responses to Plasmodium falciparum-Infected Erythrocytes
Daniel S. Korbel, Kirsty C. Newman, Catarina R. Almeida, Daniel M. Davis, and Eleanor M. Riley
J Immunol 2005 175: 7466-7473. [Abstract] [Full Text] [PDF]  

Coordinate Expression of CC Chemokine Ligand 5, Granulysin, and Perforin in CD8+ T Cells Provides a Host Defense Mechanism against Mycobacterium tuberculosis
Frank Stegelmann, Max Bastian, Kay Swoboda, Rauf Bhat, Viviane Kiessler, Alan M. Krensky, Martin Roellinghoff, Robert L. Modlin, and Steffen Stenger
J Immunol 2005 175: 7474-7483. [Abstract] [Full Text] [PDF]  

Toll-IL-1 Receptor Domain-Containing Adaptor Protein Is Critical for Early Lung Immune Responses against Escherichia coli Lipopolysaccharide and Viable Escherichia coli
Samithamby Jeyaseelan, Rizwan Manzer, Scott K. Young, Masahiro Yamamoto, Shizuo Akira, Robert J. Mason, and G. Scott Worthen
J Immunol 2005 175: 7484-7495. [Abstract] [Full Text] [PDF]  

A Model Vaccine Exploiting Fungal Mannosylation to Increase Antigen Immunogenicity
Jennifer S. Lam, Michael K. Mansour, Charles A. Specht, and Stuart M. Levitz
J Immunol 2005 175: 7496-7503. [Abstract] [Full Text] [PDF]  

The Complex Mechanism of Antibody-Mediated Clearance of Bordetella from the Lungs Requires TLR4
Girish S. Kirimanjeswara, Paul B. Mann, Mylisa Pilione, Mary J. Kennett, and Eric T. Harvill
J Immunol 2005 175: 7504-7511. [Abstract] [Full Text] [PDF]  

The Exopolysaccharide Alginate Protects Pseudomonas aeruginosa Biofilm Bacteria from IFN-{gamma}-Mediated Macrophage Killing
Jeff G. Leid, Carey J. Willson, Mark E. Shirtliff, Daniel J. Hassett, Matthew R. Parsek, and Alyssa K. Jeffers
J Immunol 2005 175: 7512-7518. [Abstract] [Full Text] [PDF]  

The Impairment of CD8 Responses Limits the Selection of Escape Mutations in Acute Hepatitis C Virus Infection
Simona Urbani, Barbara Amadei, Elisabetta Cariani, Paola Fisicaro, Alessandra Orlandini, Gabriele Missale, and Carlo Ferrari
J Immunol 2005 175: 7519-7529. [Abstract] [Full Text] [PDF]  

Lung NF-{kappa}B Activation and Neutrophil Recruitment Require IL-1 and TNF Receptor Signaling during Pneumococcal Pneumonia
Matthew R. Jones, Benjamin T. Simms, Michal M. Lupa, Mariya S. Kogan, and Joseph P. Mizgerd
J Immunol 2005 175: 7530-7535. [Abstract] [Full Text] [PDF]  

A Predominant Role for Antibody in Acquired Immunity to Chlamydial Genital Tract Reinfection
Sandra G. Morrison and Richard P. Morrison
J Immunol 2005 175: 7536-7542. [Abstract] [Full Text] [PDF]  

Molecular and Cellular Basis of the Retrovirus Resistance in I/LnJ Mice
Laure K. Case, Alexandra Purdy, and Tatyana V. Golovkina
J Immunol 2005 175: 7543-7549. [Abstract] [Full Text] [PDF]  

Diversity in the Acute CD8 T Cell Response to Vaccinia Virus in Humans
Lichen Jing, Tiana M. Chong, Christopher L. McClurkan, Jay Huang, Brian T. Story, and David M. Koelle
J Immunol 2005 175: 7550-7559. [Abstract] [Full Text] [PDF]  

Cationic Polypeptides Are Required for Anti-HIV-1 Activity of Human Vaginal Fluid
Nitya Venkataraman, Amy L. Cole, Pavel Svoboda, Jan Pohl, and Alexander M. Cole
J Immunol 2005 175: 7560-7567. [Abstract] [Full Text] [PDF]  

Human NK Cells Inhibit Cytomegalovirus Replication through a Noncytolytic Mechanism Involving Lymphotoxin-Dependent Induction of IFN-{beta}
Ann-Charlotte Iversen, Paula S. Norris, Carl F. Ware, and Chris A. Benedict
J Immunol 2005 175: 7568-7574. [Abstract] [Full Text] [PDF]  

Human CD4+ T Cells Induced by Synthetic Peptide Malaria Vaccine Are Comparable to Cells Elicited by Attenuated Plasmodium falciparum Sporozoites
Jaime Mauricio Calvo-Calle, Giane A. Oliveira, and Elizabeth H. Nardin
J Immunol 2005 175: 7575-7585. [Abstract] [Full Text] [PDF]  

Preferential Targeting of CD4-CCR5 Complexes with Bifunctional Inhibitors: A Novel Approach to Block HIV-1 Infection
Matthias Mack, Jochen Pfirstinger, Jürgen Haas, Peter J. Nelson, Peter Kufer, Gert Riethmüller, and Detlef Schlöndorff
J Immunol 2005 175: 7586-7593. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Viral Inhibition of IL-1- and Neutrophil Elastase-Induced Inflammatory Responses in Bronchial Epithelial Cells
Tomás P. Carroll, Catherine M. Greene, Clifford C. Taggart, Andrew G. Bowie, Shane J. O’Neill, and Noel G. McElvaney
J Immunol 2005 175: 7594-7601. [Abstract] [Full Text] [PDF]  

Impaired Fc{epsilon}RI-Dependent Gene Expression and Defective Eicosanoid and Cytokine Production as a Consequence of Fyn Deficiency in Mast Cells
Gregorio Gomez, Claudia Gonzalez-Espinosa, Sandra Odom, Gabriela Baez, M. Eugenia Cid, John J. Ryan, and Juan Rivera
J Immunol 2005 175: 7602-7610. [Abstract] [Full Text] [PDF]  

Potentiation of Caspase-1 Activation by the P2X7 Receptor Is Dependent on TLR Signals and Requires NF-{kappa}B-Driven Protein Synthesis
J. Michelle Kahlenberg, Kathleen C. Lundberg, Sylvia B. Kertesy, Yan Qu, and George R. Dubyak
J Immunol 2005 175: 7611-7622. [Abstract] [Full Text] [PDF]  

Inhibitory Effects of Chloride on the Activation of Caspase-1, IL-1{beta} Secretion, and Cytolysis by the P2X7 Receptor
Philip A. Verhoef, Sylvia B. Kertesy, Kathleen Lundberg, J. Michelle Kahlenberg, and George R. Dubyak
J Immunol 2005 175: 7623-7634. [Abstract] [Full Text] [PDF]  

Protein Kinase C{theta} Controls Th1 Cells in Experimental Autoimmune Encephalomyelitis
Shahram Salek-Ardakani, Takanori So, Beth S. Halteman, Amnon Altman, and Michael Croft
J Immunol 2005 175: 7635-7641. [Abstract] [Full Text] [PDF]  

Resistance of Collagenase-2 (Matrix Metalloproteinase-8)-Deficient Mice to TNF-Induced Lethal Hepatitis
Philippe Van Lint, Ben Wielockx, Leen Puimège, Agnès Noël, Carlos López-Otin, and Claude Libert
J Immunol 2005 175: 7642-7649. [Abstract] [Full Text] [PDF]  

A Role for the Neuronal Protein Collapsin Response Mediator Protein 2 in T Lymphocyte Polarization and Migration
Peggy Vincent, Yves Collette, Romain Marignier, Carine Vuaillat, Véronique Rogemond, Nathalie Davoust, Christophe Malcus, Sylvie Cavagna, Antoine Gessain, Irma Machuca-Gayet, Marie-Françoise Belin, Tam Quach, and Pascale Giraudon
J Immunol 2005 175: 7650-7660. [Abstract] [Full Text] [PDF]  

Hepatic Ischemia/Reperfusion Injury Involves Functional TLR4 Signaling in Nonparenchymal Cells
Allan Tsung, Rosemary A. Hoffman, Kunihiko Izuishi, Nathan D. Critchlow, Atsunori Nakao, Meagan H. Chan, Michael T. Lotze, David A. Geller, and Timothy R. Billiar
J Immunol 2005 175: 7661-7668. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Evidence for Multiple Shared Antigenic Determinants within Ro60 and Other Lupus-Related Ribonucleoprotein Autoantigens in Human Autoimmune Responses
Rahul Pal, Umesh S. Deshmukh, Yukiko Ohyama, Qiang Fang, Carol C. Kannapell, Felicia Gaskin, and Shu Man Fu
J Immunol 2005 175: 7669-7677. [Abstract] [Full Text] [PDF]  

T Cell-Regulated Neutrophilic Inflammation in Autoinflammatory Diseases
Monika Keller, Zoi Spanou, Patrick Schaerli, Markus Britschgi, Nikhil Yawalkar, Michael Seitz, Peter M. Villiger, and Werner J. Pichler
J Immunol 2005 175: 7678-7686. [Abstract] [Full Text] [PDF]  

Enhancement of Adenovirus-Mediated Gene Delivery to Rheumatoid Arthritis Synoviocytes and Synovium by Fiber Modifications: Role of Arginine-Glycine-Aspartic Acid (RGD)- and Non-RGD-Binding Integrins
Myew-Ling Toh, Saw-See Hong, Fons van de Loo, Laure Franqueville, Leif Lindholm, Wim van den Berg, Pierre Boulanger, and Pierre Miossec
J Immunol 2005 175: 7687-7698. [Abstract] [Full Text] [PDF]  

Cell- Rather Than Antibody-Mediated Immunity Leads to the Development of Profound Thrombocytopenia during Experimental Plasmodium berghei Malaria
Irene Gramaglia, Herman Sahlin, John P. Nolan, John A. Frangos, Marcos Intaglietta, and Henri C. van der Heyde
J Immunol 2005 175: 7699-7707. [Abstract] [Full Text] [PDF]  

Increased Expression of Integrin {alpha}v{beta}3 Contributes to the Establishment of Autocrine TGF-{beta} Signaling in Scleroderma Fibroblasts
Yoshihide Asano, Hironobu Ihn, Kenichi Yamane, Masatoshi Jinnin, Yoshihiro Mimura, and Kunihiko Tamaki
J Immunol 2005 175: 7708-7718. [Abstract] [Full Text] [PDF]  

Staphylococcal Protein A Deletes B-1a and Marginal Zone B Lymphocytes Expressing Human Immunoglobulins: An Immune Evasion Mechanism
Muriel Viau, Nancy S. Longo, Peter E. Lipsky, and Moncef Zouali
J Immunol 2005 175: 7719-7727. [Abstract] [Full Text] [PDF]  

Tolerogenic Treatment of Lupus Mice with Consensus Peptide Induces Foxp3-Expressing, Apoptosis-Resistant, TGF{beta}-Secreting CD8+ T Cell Suppressors
Bevra H. Hahn, Ram Pyare Singh, Antonio La Cava, and Fanny M. Ebling
J Immunol 2005 175: 7728-7737. [Abstract] [Full Text] [PDF]  

Effector Function of Diabetogenic CD4 Th1 T Cell Clones: A Central Role for TNF-{alpha}
Joseph Cantor and Kathryn Haskins
J Immunol 2005 175: 7738-7745. [Abstract] [Full Text] [PDF]  

Analysis of the Cellular Mechanism of Antitumor Responses and Autoimmunity in Patients Treated with CTLA-4 Blockade
Ajay V. Maker, Peter Attia, and Steven A. Rosenberg
J Immunol 2005 175: 7746-7754. [Abstract] [Full Text] [PDF]  

Analysis of GAD65 Autoantibodies in Stiff-Person Syndrome Patients
Raghavanpillai Raju, Jefferson Foote, J. Paul Banga, Tyler R. Hall, Carolyn J. Padoa, Marinos C. Dalakas, Eva Ortqvist, and Christiane S. Hampe
J Immunol 2005 175: 7755-7762. [Abstract] [Full Text] [PDF]  

In Vivo Correction of Complement Regulatory Protein Deficiency with an Inhibitor Targeting the Red Blood Cell Membrane
Dirk Spitzer, Jacqueline Unsinger, Dailing Mao, Xiaobo Wu, Hector Molina, and John P. Atkinson
J Immunol 2005 175: 7763-7770. [Abstract] [Full Text] [PDF]  

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