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On the cover: Confocal micrograph of pulmonary C3 deposition following gastrointestinal ischemia/reperfusion in MBL-null mice. C3 deposition was independent of C1q or MBL, but dependent on the presence of C2. Image illustrates C3 deposition in MBL-null mice given recombinant human MBL and inhibited with a humanized anti-human MBL mAb, 3F8. Hart M. L., K. A. Ceonzo, L. A. Shaffer, K. Takahashi, R. P. Rother, W. R. Reenstra, J. A. Buras, and G. L. Stahl. 2005. Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q. J. Immunol. 174: 6373–6380.
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