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On the cover: Histological staining (H&E) showing extensive lymphatic infiltration in the submandibular glands of female N5 mutant NOD.E2f1-/- mice. E2f1 homozygous mutant NOD mice were highly predisposed to the development of insulin-dependent diabetes mellitus and Sjögren's syndrome. Salam et al. E2f1 mutation induces early onset of diabetes and Sjögren's syndrome in nonobese diabetic mice. J. Immunol. 173:4908.
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