IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2004 173: 1497-1498. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Making the Connection: Antibody Responsiveness and MHC Genes

Jack R. Bennink
J Immunol 2004 173: 1499. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Genetic Control of the Antibody Responses: Relationship between Immune Response and Histocompatibility (H-2) Type. Science, 1969, 163:1207–1208

Hugh O. McDevitt and Allen Chinitz
J Immunol 2004 173: 1500-1501. [PDF]  

BRIEF REVIEWS:

Cysteinyl Leukotrienes and Their Receptors: Cellular Distribution and Function in Immune and Inflammatory Responses

Yoshihide Kanaoka and Joshua A. Boyce
J Immunol 2004 173: 1503-1510. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Membrane Nanotubes Connect Immune Cells

Björn Önfelt, Shlomo Nedvetzki, Kumiko Yanagi, and Daniel M. Davis
J Immunol 2004 173: 1511-1513. [Abstract] [Full Text] [PDF]  

Cutting Edge: Innate Production of IFN- by NK Cells Is Independent of Epigenetic Modification of the IFN- Promoter

Cristina M. Tato, Gislâine A. Martins, Frances A. High, Catherine B. DiCioccio, Steven L. Reiner, and Christopher A. Hunter
J Immunol 2004 173: 1514-1517. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Termination of Antigen-Specific Immunity by CD95 Ligand (Fas Ligand) and IL-10

Ramon Barreiro, Gary Luker, John Herndon, and Thomas A. Ferguson
J Immunol 2004 173: 1519-1525. [Abstract] [Full Text] [PDF]  

Antigen-Processing Machinery in Human Dendritic Cells: Up-Regulation by Maturation and Down-Regulation by Tumor Cells

Theresa L. Whiteside, Joanna Stanson, Michael R. Shurin, and Soldano Ferrone
J Immunol 2004 173: 1526-1534. [Abstract] [Full Text] [PDF]  

Regulation of IFN Regulatory Factor-7 and IFN- Production by Enveloped Virus and Lipopolysaccharide in Human Plasmacytoid Dendritic Cells

Jihong Dai, Nicholas J. Megjugorac, Sheela B. Amrute, and Patricia Fitzgerald-Bocarsly
J Immunol 2004 173: 1535-1548. [Abstract] [Full Text] [PDF]  

Ectopic Expression of HLA-DO in Mouse Dendritic Cells Diminishes MHC Class II Antigen Presentation

Jennifer L. Fallas, Helen M. Tobin, Olivia Lou, Donglin Guo, Derek B. Sant’Angelo, and Lisa K. Denzin
J Immunol 2004 173: 1549-1560. [Abstract] [Full Text] [PDF]  

In Vivo Pattern of Lipopolysaccharide and Anti-CD3-Induced NF-B Activation Using a Novel Gene-Targeted Enhanced GFP Reporter Gene Mouse

Scott T. Magness, Humberto Jijon, Nancy Van Houten Fisher, Ned E. Sharpless, David A. Brenner, and Christian Jobin
J Immunol 2004 173: 1561-1570. [Abstract] [Full Text] [PDF]  

Ligand Binding to Inhibitory Killer Cell Ig-Like Receptors Induce Colocalization with Src Homology Domain 2-Containing Protein Tyrosine Phosphatase 1 and Interruption of Ongoing Activation Signals

Yatin M. Vyas, Hina Maniar, Clay E. Lyddane, Michel Sadelain, and Bo Dupont
J Immunol 2004 173: 1571-1578. [Abstract] [Full Text] [PDF]  

Differences in the Kinetics, Amplitude, and Localization of ERK Activation in Anergy and Priming Revealed at the Level of Individual Primary T Cells by Laser Scanning Cytometry

Claire L. Adams, Angela M. Grierson, Allan M. Mowat, Margaret M. Harnett, and Paul Garside
J Immunol 2004 173: 1579-1586. [Abstract] [Full Text] [PDF]  

T Cell Regulation of IFN- Production by Central Nervous System-Infiltrating Encephalitogenic T Cells: Correlation with Recovery from Experimental Autoimmune Encephalomyelitis

Eugene D. Ponomarev, Marina Novikova, Maryam Yassai, Marian Szczepanik, Jack Gorski, and Bonnie N. Dittel
J Immunol 2004 173: 1587-1595. [Abstract] [Full Text] [PDF]  

Antisense Knockdown of Sphingosine Kinase 1 in Human Macrophages Inhibits C5a Receptor-Dependent Signal Transduction, Ca²⁺ Signals, Enzyme Release, Cytokine Production, and Chemotaxis

Alirio J. Melendez and Farazeela Bte Mohd Ibrahim
J Immunol 2004 173: 1596-1603. [Abstract] [Full Text] [PDF]  

Regulation of Thymus Size by Competition for Stromal Niches among Early T Cell Progenitors

Susan E. Prockop and Howard T. Petrie
J Immunol 2004 173: 1604-1611. [Abstract] [Full Text] [PDF]  

IB Kinase 2 Deficiency in T Cells Leads to Defects in Priming, B Cell Help, Germinal Center Reactions, and Homeostatic Expansion

Marc Schmidt-Supprian, Jane Tian, Hongbin Ji, Cox Terhorst, Atul K. Bhan, Ethan P. Grant, Manolis Pasparakis, Stefano Casola, Anthony J. Coyle, and Klaus Rajewsky
J Immunol 2004 173: 1612-1619. [Abstract] [Full Text] [PDF]  

Critical Roles of CXC Chemokine Ligand 16/Scavenger Receptor that Binds Phosphatidylserine and Oxidized Lipoprotein in the Pathogenesis of Both Acute and Adoptive Transfer Experimental Autoimmune Encephalomyelitis

Noriko Fukumoto, Takeshi Shimaoka, Harutoshi Fujimura, Saburo Sakoda, Makoto Tanaka, Toru Kita, and Shin Yonehara
J Immunol 2004 173: 1620-1627. [Abstract] [Full Text] [PDF]  

Lipid Raft-Associated GTPase Signaling Controls Morphology and CD8⁺ T Cell Stimulatory Capacity of Human Dendritic Cells

Silvia Jaksits, Wolfgang Bauer, Ernst Kriehuber, Maximilian Zeyda, Thomas M. Stulnig, Georg Stingl, Edda Fiebiger, and Dieter Maurer
J Immunol 2004 173: 1628-1639. [Abstract] [Full Text] [PDF]  

In Vivo Generated Th1 Cells Can Migrate to B Cell Follicles to Support B Cell Responses

Karen M. Smith, James M. Brewer, Catherine M. Rush, Jillian Riley, and Paul Garside
J Immunol 2004 173: 1640-1646. [Abstract] [Full Text] [PDF]  

CpG-C Immunostimulatory Oligodeoxyribonucleotide Activation of Plasmacytoid Dendritic Cells in Rhesus Macaques to Augment the Activation of IFN--Secreting Simian Immunodeficiency Virus-Specific T Cells

Natalia Teleshova, Jessica Kenney, Jennifer Jones, Jason Marshall, Gary Van Nest, Jason Dufour, Rudolf Bohm, Jeffrey D. Lifson, Agegnehu Gettie, and Melissa Pope
J Immunol 2004 173: 1647-1657. [Abstract] [Full Text] [PDF]  

Differential Roles for Wiskott-Aldrich Syndrome Protein in Immune Synapse Formation and IL-2 Production

Judy L. Cannon and Janis K. Burkhardt
J Immunol 2004 173: 1658-1662. [Abstract] [Full Text] [PDF]  

IFN- Subtypes Differentially Affect Human T Cell Motility

Graham R. Foster, Siti H. Masri, Rachel David, Meleri Jones, Arpita Datta, Giovanna Lombardi, Laura Runkell, Carole de Dios, Irene Sizing, Martha J. James, and Federica M. Marelli-Berg
J Immunol 2004 173: 1663-1670. [Abstract] [Full Text] [PDF]  

T Cells Signaled by NF-B^– Dendritic Cells Are Sensitized Not Anergic to Subsequent Activation

Angus G. Thompson, Brendan J. O’Sullivan, Heather Beamish, and Ranjeny Thomas
J Immunol 2004 173: 1671-1680. [Abstract] [Full Text] [PDF]  

Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor -Chain That Behaves as a Specific, High Affinity IL-15 Antagonist

Erwan Mortier, Jérôme Bernard, Ariane Plet, and Yannick Jacques
J Immunol 2004 173: 1681-1688. [Abstract] [Full Text] [PDF]  

Cross-Reactive TCR Responses to Self Antigens Presented by Different MHC Class II Molecules

Marcin P. Mycko, Hanspeter Waldner, David E. Anderson, Katarzyna D. Bourcier, Kai W. Wucherpfennig, Vijay K. Kuchroo, and David A. Hafler
J Immunol 2004 173: 1689-1698. [Abstract] [Full Text] [PDF]  

HLA-B27 Heavy Chain Homodimers Are Expressed in HLA-B27 Transgenic Rodent Models of Spondyloarthritis and Are Ligands for Paired Ig-Like Receptors

Simon Kollnberger, Lucy A. Bird, Matthew Roddis, Cecile Hacquard-Bouder, Hiromi Kubagawa, Helen C. Bodmer, Maxime Breban, Andrew J. McMichael, and Paul Bowness
J Immunol 2004 173: 1699-1710. [Abstract] [Full Text] [PDF]  

The Gads (GrpL) Adaptor Protein Regulates T Cell Homeostasis

Thomas M. Yankee, Theodore J. Yun, Kevin E. Draves, Kolumam Ganesh, Michael J. Bevan, Kaja Murali-Krishna, and Edward A. Clark
J Immunol 2004 173: 1711-1720. [Abstract] [Full Text] [PDF]  

MUC1/sec-Expressing Tumors Are Rejected In Vivo by a T Cell-Dependent Mechanism and Secrete High Levels of CCL2

Joseph F. Grosso, Lynn M. Herbert, Jennifer L. Owen, and Diana M. Lopez
J Immunol 2004 173: 1721-1730. [Abstract] [Full Text] [PDF]  

A Synthetic Peptide Homologous to Functional Domain of Human IL-10 Down-Regulates Expression of MHC Class I and Transporter Associated with Antigen Processing 1/2 in Human Melanoma Cells

Mónica Kurte, Mercedes López, Adam Aguirre, Alejandro Escobar, Juan Carlos Aguillón, Jehad Charo, Christian G. Larsen, Rolf Kiessling, and Flavio Salazar-Onfray
J Immunol 2004 173: 1731-1737. [Abstract] [Full Text] [PDF]  

The Rate of the CD8-Dependent Initial Reduction in Tumor Volume Is Not Limited by Contact-Dependent Perforin, Fas Ligand, or TNF-Mediated Cytolysis

Joseph A. Hollenbaugh, Joyce Reome, Mark Dobrzanski, and Richard W. Dutton
J Immunol 2004 173: 1738-1743. [Abstract] [Full Text] [PDF]  

Endogenous Nitric Oxide Protects against T Cell-Dependent Lethality during Graft-versus-Host Disease and Idiopathic Pneumonia Syndrome

David Hongo, J. Scott Bryson, Alan M. Kaplan, and Donald A. Cohen
J Immunol 2004 173: 1744-1756. [Abstract] [Full Text] [PDF]  

Antigen Presentation to Celiac Lesion-Derived T Cells of a 33-Mer Gliadin Peptide Naturally Formed by Gastrointestinal Digestion

Shuo-Wang Qiao, Elin Bergseng, Øyvind Molberg, Jiang Xia, Burkhard Fleckenstein, Chaitan Khosla, and Ludvig M. Sollid
J Immunol 2004 173: 1757-1762. [Abstract] [Full Text] [PDF]  

Mouse Lysozyme-M Knockout Mice Reveal How the Self-Determinant Hierarchy Shapes the T Cell Repertoire against This Circulating Self Antigen in Wild-Type Mice

Pratima Sinha, Howard H. Chi, Hong R. Kim, Björn E. Clausen, Brian Pederson, Eli E. Sercarz, Irmgard Forster, and Kamal D. Moudgil
J Immunol 2004 173: 1763-1771. [Abstract] [Full Text] [PDF]  

-Fetoprotein Impairs APC Function and Induces Their Apoptosis

Soon Ho Um, Catherine Mulhall, Akeel Alisa, Annette Robyn Ives, John Karani, Roger Williams, Antonio Bertoletti, and Shahriar Behboudi
J Immunol 2004 173: 1772-1778. [Abstract] [Full Text] [PDF]  

ICOS Expression by Activated Human Th Cells Is Enhanced by IL-12 and IL-23: Increased ICOS Expression Enhances the Effector Function of Both Th1 and Th2 Cells

Lianne Wassink, Pedro L. Vieira, Hermelijn H. Smits, Gillian A. Kingsbury, Anthony J. Coyle, Martien L. Kapsenberg, and Eddy A. Wierenga
J Immunol 2004 173: 1779-1786. [Abstract] [Full Text] [PDF]  

Direct Measurement of T Cell Subset Kinetics In Vivo in Elderly Men and Women

Diana L. Wallace, Yan Zhang, Hala Ghattas, Andrew Worth, Andrew Irvine, Andrea R. Bennett, George E. Griffin, Peter C. L. Beverley, David F. Tough, and Derek C. Macallan
J Immunol 2004 173: 1787-1794. [Abstract] [Full Text] [PDF]  

T Cell Immunity to Type II Collagen in the Biobreeding Rat: The Identification and Characterization of RT1^u-Restricted T Cell Epitopes on 1(II)

Michael A. Cremer, Xiu J. Ye, Linda K. Myers, David D. Brand, Edward F. Rosloniec, and Andrew H. Kang
J Immunol 2004 173: 1795-1801. [Abstract] [Full Text] [PDF]  

Cyclic Adenosine 5'-Monophosphate Response Element Binding Protein Plays a Central Role in Mediating Proliferation and Differentiation Downstream of the Pre-TCR Complex in Developing Thymocytes

Gillian C. Grady, Susan M. Mason, Jillian Stephen, Juan Carlos Zúñiga-Pflücker, and Alison M. Michie
J Immunol 2004 173: 1802-1810. [Abstract] [Full Text] [PDF]  

Inactivation of c-Cbl or Cbl-b Differentially Affects Signaling from the High Affinity IgE Receptor

Juan Zhang, Yungping J. Chiang, Richard J. Hodes, and Reuben P. Siraganian
J Immunol 2004 173: 1811-1818. [Abstract] [Full Text] [PDF]  

MHC Class I-Independent Recognition of NK-Activating Receptor KIR2DS4

Gil Katz, Roi Gazit, Tal I. Arnon, Tsufit Gonen-Gross, Gabi Tarcic, Gal Markel, Raizy Gruda, Hagit Achdout, Olga Drize, Sharon Merims, and Ofer Mandelboim
J Immunol 2004 173: 1819-1825. [Abstract] [Full Text] [PDF]  

Characterization of Distinct Conventional and Plasmacytoid Dendritic Cell-Committed Precursors in Murine Bone Marrow

Jun Diao, Erin Winter, Wenhao Chen, Claude Cantin, and Mark S. Cattral
J Immunol 2004 173: 1826-1833. [Abstract] [Full Text] [PDF]  

Emergence of a CD4⁺CD28^– Granzyme B⁺, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection

Ester M. M. van Leeuwen, Ester B. M. Remmerswaal, Mireille T. M. Vossen, Ajda T. Rowshani, Pauline M. E. Wertheim-van Dillen, René A. W. van Lier, and Ineke J. M. ten Berge
J Immunol 2004 173: 1834-1841. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Transcription-Dependent Somatic Hypermutation Occurs at Similar Levels on Functional and Nonfunctional Rearranged IgH Alleles

Laurent Delpy, Christophe Sirac, Caroline Le Morvan, and Michel Cogné
J Immunol 2004 173: 1842-1848. [Abstract] [Full Text] [PDF]  

De Novo Synthesized RelB Mediates TNF-Induced Up-Regulation of the Human Polymeric Ig Receptor

Hilde Schjerven, Thien N. Tran, Per Brandtzaeg, and Finn-Eirik Johansen
J Immunol 2004 173: 1849-1857. [Abstract] [Full Text] [PDF]  

Endogenous Expression of Activation-Induced Cytidine Deaminase in Cell Line WEHI-231

Freia J. X. Spillmann and Matthias Wabl
J Immunol 2004 173: 1858-1867. [Abstract] [Full Text] [PDF]  

Histidines Are Critical for Heparin-Dependent Activation of Mast Cell Tryptase

Jenny Hallgren, Stefan Bäckström, Sergio Estrada, Maria Thuveson, and Gunnar Pejler
J Immunol 2004 173: 1868-1875. [Abstract] [Full Text] [PDF]  

B Cell Lipid Rafts Regulate Both Peptide-Dependent and Peptide-Independent APC-T Cell Interaction

Niclas Setterblad, Stéphane Bécart, Dominique Charron, and Nuala Mooney
J Immunol 2004 173: 1876-1886. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

IL-23 Provides a Limited Mechanism of Resistance to Acute Toxoplasmosis in the Absence of IL-12

Linda A. Lieberman, Fabiola Cardillo, Alexander M. Owyang, Donna M. Rennick, Daniel J. Cua, Robert A. Kastelein, and Christopher A. Hunter
J Immunol 2004 173: 1887-1893. [Abstract] [Full Text] [PDF]  

Innate BALB/c Enteric Epithelial Responses to Trichinella spiralis: Inducible Expression of a Novel Goblet Cell Lectin, Intelectin-2, and Its Natural Deletion in C57BL/10 Mice

Alan D. Pemberton, Pamela A. Knight, John Gamble, William H. Colledge, Jin-Kyu Lee, Michael Pierce, and Hugh R. P. Miller
J Immunol 2004 173: 1894-1901. [Abstract] [Full Text] [PDF]  

LacdiNAc-Glycans Constitute a Parasite Pattern for Galectin-3-Mediated Immune Recognition

Timo K. van den Berg, Henk Honing, Niels Franke, Alexandra van Remoortere, Wietske E. C. M. Schiphorst, Fu-Tong Liu, André M. Deelder, Richard D. Cummings, Cornelis H. Hokke, and Irma van Die
J Immunol 2004 173: 1902-1907. [Abstract] [Full Text] [PDF]  

MAdCAM-1 Expressing Sacral Lymph Node in the Lymphotoxin -Deficient Mouse Provides a Site for Immune Generation Following Vaginal Herpes Simplex Virus-2 Infection

Kelly A. Soderberg, Melissa M. Linehan, Nancy H. Ruddle, and Akiko Iwasaki
J Immunol 2004 173: 1908-1913. [Abstract] [Full Text] [PDF]  

Innate Immune Responses to Rhodococcus equi

Patricia A. Darrah, Maria Chiara G. Monaco, Shruti Jain, Mary K. Hondalus, Douglas T. Golenbock, and David M. Mosser
J Immunol 2004 173: 1914-1924. [Abstract] [Full Text] [PDF]  

Wheat Gluten Causes Dendritic Cell Maturation and Chemokine Secretion

Marina Nikulina, Christiane Habich, Stefanie B. Flohé, Fraser W. Scott, and Hubert Kolb
J Immunol 2004 173: 1925-1933. [Abstract] [Full Text] [PDF]  

Bordetella Type III Secretion and Adenylate Cyclase Toxin Synergize to Drive Dendritic Cells into a Semimature State

Jason A. Skinner, Annette Reissinger, Hao Shen, and Ming H. Yuk
J Immunol 2004 173: 1934-1940. [Abstract] [Full Text] [PDF]  

Recognition of Variant HIV-1 Epitopes from Diverse Viral Subtypes by Vaccine-Induced CTL

Denise M. McKinney, Rhonda Skvoretz, Brian D. Livingston, Cara C. Wilson, Michelle Anders, Robert W. Chesnut, Alessandro Sette, Max Essex, Vladimir Novitsky, and Mark J. Newman
J Immunol 2004 173: 1941-1950. [Abstract] [Full Text] [PDF]  

Th Cell-Independent Immune Responses to Chimeric Hemagglutinin/Simian Human Immunodeficiency Virus-Like Particles Vaccine

Qizhi Yao, Rongxin Zhang, Lizheng Guo, Min Li, and Changyi Chen
J Immunol 2004 173: 1951-1958. [Abstract] [Full Text] [PDF]  

Bordetella pertussis Lipopolysaccharide Resists the Bactericidal Effects of Pulmonary Surfactant Protein A

Lyndsay M. Schaeffer, Francis X. McCormack, Huixing Wu, and Alison A. Weiss
J Immunol 2004 173: 1959-1965. [Abstract] [Full Text] [PDF]  

Characterization of a Mycobacterium tuberculosis Peptide That Is Recognized by Human CD4⁺ and CD8⁺ T Cells in the Context of Multiple HLA Alleles

Homayoun Shams, Peter Klucar, Steven E. Weis, Ajit Lalvani, Patrick K. Moonan, Hassan Safi, Benjamin Wizel, Katie Ewer, Gerald T. Nepom, David M. Lewinsohn, Peter Andersen, and Peter F. Barnes
J Immunol 2004 173: 1966-1977. [Abstract] [Full Text] [PDF]  

Role of IgA versus IgG in the Control of Influenza Viral Infection in the Murine Respiratory Tract

Kathryn B. Renegar, Parker A. Small, Jr, Lou G. Boykins, and Peter F. Wright
J Immunol 2004 173: 1978-1986. [Abstract] [Full Text] [PDF]  

Heat Shock Protein-Mediated Cross-Presentation of Exogenous HIV Antigen on HLA Class I and Class II

Devi SenGupta, Philip J. Norris, Todd J. Suscovich, Mina Hassan-Zahraee, Howell F. Moffett, Alicja Trocha, Rika Draenert, Philip J. R. Goulder, Robert J. Binder, Daniel L. Levey, Bruce D. Walker, Pramod K. Srivastava, and Christian Brander
J Immunol 2004 173: 1987-1993. [Abstract] [Full Text] [PDF]  

Neutrophil Involvement in Cross-Priming CD8⁺ T Cell Responses to Bacterial Antigens

Amy R. Tvinnereim, Sara E. Hamilton, and John T. Harty
J Immunol 2004 173: 1994-2002. [Abstract] [Full Text] [PDF]  

MyD88 Plays a Unique Role in Host Defense but Not Arthritis Development in Lyme Disease

Devin D. Bolz, Rhianna S. Sundsbak, Ying Ma, Shizuo Akira, Carsten J. Kirschning, James F. Zachary, John H. Weis, and Janis J. Weis
J Immunol 2004 173: 2003-2010. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Cyclooxygenase (COX)-2 Inhibitor Celecoxib Abrogates TNF-Induced NF-B Activation through Inhibition of Activation of IB Kinase and Akt in Human Non-Small Cell Lung Carcinoma: Correlation with Suppression of COX-2 Synthesis

Shishir Shishodia, Dimpy Koul, and Bharat B. Aggarwal
J Immunol 2004 173: 2011-2022. [Abstract] [Full Text] [PDF]  

Heme Inhibits Human Neutrophil Apoptosis: Involvement of Phosphoinositide 3-Kinase, MAPK, and NF-B

Maria Augusta Arruda, Adriano G. Rossi, Marta S. de Freitas, Christina Barja-Fidalgo, and Aurélio V. Graça-Souza
J Immunol 2004 173: 2023-2030. [Abstract] [Full Text] [PDF]  

Different Domains of Pseudomonas aeruginosa Exoenzyme S Activate Distinct TLRs

Slava Epelman, Danuta Stack, Chris Bell, Erica Wong, Graham G. Neely, Stephan Krutzik, Kensuke Miyake, Paul Kubes, Lori D. Zbytnuik, Ling Ling Ma, Xiaobin Xie, Donald E. Woods, and Christopher H. Mody
J Immunol 2004 173: 2031-2040. [Abstract] [Full Text] [PDF]  

Phenyl Methimazole Inhibits TNF--Induced VCAM-1 Expression in an IFN Regulatory Factor-1-Dependent Manner and Reduces Monocytic Cell Adhesion to Endothelial Cells

Nilesh M. Dagia, Norikazu Harii, Antonella E. Meli, Xiaolu Sun, Christopher J. Lewis, Leonard D. Kohn, and Douglas J. Goetz
J Immunol 2004 173: 2041-2049. [Abstract] [Full Text] [PDF]  

Blockade of CXCR3 Receptor:Ligand Interactions Reduces Leukocyte Recruitment to the Lung and the Severity of Experimental Idiopathic Pneumonia Syndrome

Gerhard C. Hildebrandt, Leigh A. Corrion, Krystyna M. Olkiewicz, Bao Lu, Kathleen Lowler, Ulrich A. Duffner, Bethany B. Moore, William A. Kuziel, Chen Liu, and Kenneth R. Cooke
J Immunol 2004 173: 2050-2059. [Abstract] [Full Text] [PDF]  

Platelet Factor 4/CXCL4 Induces Phagocytosis and the Generation of Reactive Oxygen Metabolites in Mononuclear Phagocytes Independently of Gi Protein Activation or Intracellular Calcium Transients

Olga Pervushina, Barbara Scheuerer, Norbert Reiling, Lars Behnke, Jens.-M. Schröder, Brigitte Kasper, Ernst Brandt, Silvia Bulfone-Paus, and Frank Petersen
J Immunol 2004 173: 2060-2067. [Abstract] [Full Text] [PDF]  

Responses of Neutrophils to Anti-Integrin Antibodies Depends on Costimulation through Low Affinity FcRs: Full Activation Requires Both Integrin and Nonintegrin Signals

Zoltán Jakus, Giorgio Berton, Erzsébet Ligeti, Clifford A. Lowell, and Attila Mócsai
J Immunol 2004 173: 2068-2077. [Abstract] [Full Text] [PDF]  

Liver-Expressed Chemokine/CC Chemokine Ligand 16 Attracts Eosinophils by Interacting with Histamine H4 Receptor

Takashi Nakayama, Yoshiko Kato, Kunio Hieshima, Daisuke Nagakubo, Yuichi Kunori, Takao Fujisawa, and Osamu Yoshie
J Immunol 2004 173: 2078-2083. [Abstract] [Full Text] [PDF]  

MIP-1 Promotes Receptor Activator of NF-B Ligand-Induced Osteoclast Formation and Survival

Yoshimasa Okamatsu, David Kim, Ricardo Battaglino, Hajime Sasaki, Ulrike Späte, and Philip Stashenko
J Immunol 2004 173: 2084-2090. [Abstract] [Full Text] [PDF]  

A Stable Aspirin-Triggered Lipoxin A₄ Analog Blocks Phosphorylation of Leukocyte-Specific Protein 1 in Human Neutrophils

Taisuke Ohira, Gerard Bannenberg, Makoto Arita, Minoru Takahashi, Qingyuan Ge, Thomas E. Van Dyke, Gregory L. Stahl, Charles N. Serhan, and John A. Badwey
J Immunol 2004 173: 2091-2098. [Abstract] [Full Text] [PDF]  

Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF--Mediated Pulmonary Fibrosis

Philippe Bonniaud, Martin Kolb, Tom Galt, Jennifer Robertson, Clinton Robbins, Martin Stampfli, Carol Lavery, Peter J. Margetts, Anita B. Roberts, and Jack Gauldie
J Immunol 2004 173: 2099-2108. [Abstract] [Full Text] [PDF]  

Protective Role of Arginase in a Mouse Model of Colitis

Alain P. Gobert, Yulan Cheng, Mahmood Akhtar, Benjamin D. Mersey, Darren R. Blumberg, Raymond K. Cross, Rupesh Chaturvedi, Cinthia B. Drachenberg, Jean-Luc Boucher, Amy Hacker, Robert A. Casero, Jr, and Keith T. Wilson
J Immunol 2004 173: 2109-2117. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease

Keishi Fujio, Akiko Okamoto, Hiroyuki Tahara, Masaaki Abe, Yi Jiang, Toshio Kitamura, Sachiko Hirose, and Kazuhiko Yamamoto
J Immunol 2004 173: 2118-2125. [Abstract] [Full Text] [PDF]  

Absence of Immunodominant Anti-Gag p17 (SL9) Responses among Gag CTL-Positive, HIV-Uninfected Vaccine Recipients Expressing the HLA-A*0201 Allele

Guido Ferrari, Wesley Neal, Janet Ottinger, Anizsa M. Jones, Bradley H. Edwards, Paul Goepfert, Michael R. Betts, Richard A. Koup, Susan Buchbinder, M. Juliana McElrath, Jim Tartaglia, and Kent J. Weinhold
J Immunol 2004 173: 2126-2133. [Abstract] [Full Text] [PDF]  

Type I IFN Protects Against Murine Lupus

Jonathan D. Hron and Stanford L. Peng
J Immunol 2004 173: 2134-2142. [Abstract] [Full Text] [PDF]  

Gene-Engineered T Cells as a Superior Adjuvant Therapy for Metastatic Cancer

Michael H. Kershaw, Jacob T. Jackson, Nicole M. Haynes, Michele W. L. Teng, Maria Moeller, Yoshihiro Hayakawa, Shayna E. Street, Rachel Cameron, Jane E. Tanner, Joseph A. Trapani, Mark J. Smyth, and Phillip K. Darcy
J Immunol 2004 173: 2143-2150. [Abstract] [Full Text] [PDF]  

Characterization of Human T Cells That Regulate Neutrophilic Skin Inflammation

Patrick Schaerli, Markus Britschgi, Monika Keller, Urs C. Steiner, Lisa S. Steinmann, Bernhard Moser, and Werner J. Pichler
J Immunol 2004 173: 2151-2158. [Abstract] [Full Text] [PDF]  

Hepatic CD1d Expression in Hepatitis C Virus Infection and Recognition by Resident Proinflammatory CD1d-Reactive T Cells

Emanuele Durante-Mangoni, RuoJie Wang, Angela Shaulov, Qi He, Imad Nasser, Nezam Afdhal, Margaret J. Koziel, and Mark A. Exley
J Immunol 2004 173: 2159-2166. [Abstract] [Full Text] [PDF]  

Schistosoma mansoni and -Galactosylceramide: Prophylactic Effect of Th1 Immune Suppression in a Mouse Model of Graves’ Hyperthyroidism

Yuji Nagayama, Kanji Watanabe, Masami Niwa, Sandra M. McLachlan, and Basil Rapoport
J Immunol 2004 173: 2167-2173. [Abstract] [Full Text] [PDF]  

Increased Expression and Activation of CD30 Induce Apoptosis in Human Blood Eosinophils

Abdo I. Berro, Greg A. Perry, and Devendra K. Agrawal
J Immunol 2004 173: 2174-2183. [Abstract] [Full Text] [PDF]  

Central Memory CD4⁺ T Cell Responses in Chronic HIV Infection Are Not Restored by Antiretroviral Therapy

Mohamed Elrefaei, Michael D. McElroy, Christopher P. Preas, Rebecca Hoh, Steven Deeks, Jeffrey Martin, and Huyen Cao
J Immunol 2004 173: 2184-2189. [Abstract] [Full Text] [PDF]  

Monocyte Activation by Circulating Fibronectin Fragments in HIV-1-Infected Patients

JoAnn Trial, Jose A. Rubio, Holly H. Birdsall, Maria Rodriguez-Barradas, and Roger D. Rossen
J Immunol 2004 173: 2190-2198. [Abstract] [Full Text] [PDF]  

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Shedding of the Type II IL-1 Decoy Receptor Requires a Multifunctional Aminopeptidase, Aminopeptidase Regulator of TNF Receptor Type 1 Shedding.

Xinle Cui, Farshid N. Rouhani, Feras Hawari, and Stewart J. Levine
J Immunol 2004 173: 2199. [Full Text] [PDF]  

B7 Expression on T Cells Down-Regulates Immune Responses through CTLA-4 Ligation via R-T Interactions.

Patricia A. Taylor, Christopher J. Lees, Sylvie Fournier, James P. Allison, Arlene H. Sharpe, and Bruce R. Blazar
J Immunol 2004 173: 2199. [Full Text] [PDF]  

Mechanisms of V1 T Cell Activation by Microbial Components.

Hiranmoy Das, Masahiko Sugita, and Michael B. Brenner
J Immunol 2004 173: 2199. [Full Text] [PDF]  

Distinct Transcriptional Programs Activated by Interleukin-10 with or without Lipopolysaccharide in Dendritic Cells: Induction of the B Cell-Activating Chemokine, CXC Chemokine Ligand 13.

Patrick Perrier, Fernando O. Martinez, Massimo Locati, Giancarlo Bianchi, Manuela Nebuloni, Gianluca Vago, Flavia Bazzoni, Silvano Sozzani, Paola Allavena, and Alberto Mantovani
J Immunol 2004 173: 2199-2200. [Full Text] [PDF]  

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