EDITORIALS:

Rediscovering the Pillars

Robert R. Rich
J Immunol 2004 173: 1. [Full Text] [PDF]  

IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2004 173: 3-4. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

MBP-Specific Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice

Roberto Furlan
J Immunol 2004 173: 5. [Full Text] [PDF]  

The Authors Respond

Douglas E. Faunce and Joan Stein-Streilein
J Immunol 2004 173: 5-6. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

The Beginnings of T-B Collaboration

Jonathan S. Bromberg
J Immunol 2004 173: 7-13. [Full Text] [PDF] [Original Pillars Article]  

BRIEF REVIEWS:

B Cell Positive Selection: Road Map to the Primary Repertoire?

Michael P. Cancro and John F. Kearney
J Immunol 2004 173: 15-19. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Physiologic Attenuation of Proinflammatory Transcription by the G_s Protein-Coupled A2A Adenosine Receptor In Vivo

Dmitriy Lukashev, Akio Ohta, Sergey Apasov, Jiang-Fan Chen, and Michail Sitkovsky
J Immunol 2004 173: 21-24. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Delayed and Restricted Expression Limits Putative Instructional Opportunities of V1.1/V2 TCR in / Lineage Choice in the Thymus

Anna Krotkova, Emma Smith, Gabi Nerz, Ingrid Falk, and Klaus Eichmann
J Immunol 2004 173: 25-32. [Abstract] [Full Text] [PDF]  

Differences in Signaling Molecule Organization between Naive and Memory CD4⁺ T Lymphocytes

Andrew R. O. Watson and William T. Lee
J Immunol 2004 173: 33-41. [Abstract] [Full Text] [PDF]  

Opioid Antagonist Naltrexone Disrupts Feedback Interaction between µ and Opioid Receptors in Splenocytes to Prevent Alcohol Inhibition of NK Cell Function

Nadka I. Boyadjieva, Kirti Chaturvedi, Michael M. Poplawski, and Dipak K. Sarkar
J Immunol 2004 173: 42-49. [Abstract] [Full Text] [PDF]  

Immature Dendritic Cells (DCs) Use Chemokines and Intercellular Adhesion Molecule (ICAM)-1, But Not DC-Specific ICAM-3-Grabbing Nonintegrin, to Stimulate CD4⁺ T Cells in the Absence of Exogenous Antigen

Eliana Real, Andrew Kaiser, Graça Raposo, Ali Amara, Alessandra Nardin, Alain Trautmann, and Emmanuel Donnadieu
J Immunol 2004 173: 50-60. [Abstract] [Full Text] [PDF] Data Supplement  

A Caspase-6 and Anti-Human Epidermal Growth Factor Receptor-2 (HER2) Antibody Chimeric Molecule Suppresses the Growth of HER2-Overexpressing Tumors

Yan-Ming Xu, Li-Feng Wang, Lin-Tao Jia, Xiu-Chun Qiu, Jing Zhao, Cui-Juan Yu, Rui Zhang, Feng Zhu, Cheng-Ji Wang, Bo-Quan Jin, Si-Yi Chen, and An-Gang Yang
J Immunol 2004 173: 61-67. [Abstract] [Full Text] [PDF]  

T Follicular Helper Cells Express a Distinctive Transcriptional Profile, Reflecting Their Role as Non-Th1/Th2 Effector Cells That Provide Help for B Cells

Tatyana Chtanova, Stuart G. Tangye, Rebecca Newton, Nita Frank, Martin R. Hodge, Michael S. Rolph, and Charles R. Mackay
J Immunol 2004 173: 68-78. [Abstract] [Full Text] [PDF] Data Supplement  

The Gene Related to Anergy in Lymphocytes, an E3 Ubiquitin Ligase, Is Necessary for Anergy Induction in CD4 T Cells

Christine M. Seroogy, Luis Soares, Erik A. Ranheim, Leon Su, Claire Holness, Debra Bloom, and C. Garrison Fathman
J Immunol 2004 173: 79-85. [Abstract] [Full Text] [PDF]  

Lymphotoxin and TNF Produced by B Cells Are Dispensable for Maintenance of the Follicle-Associated Epithelium but Are Required for Development of Lymphoid Follicles in the Peyer’s Patches

Alexei V. Tumanov, Dmitry V. Kuprash, Julie A. Mach, Sergei A. Nedospasov, and Alexander V. Chervonsky
J Immunol 2004 173: 86-91. [Abstract] [Full Text] [PDF]  

The Third Signal in T Cell-Mediated Autoimmune Disease?

Kamruz Darabi, Alexey Y. Karulin, Bernhard O. Boehm, Harald H. Hofstetter, Zsuzsa Fabry, Joseph C. LaManna, Juan C. Chavez, Magdalena Tary-Lehmann, and Paul V. Lehmann
J Immunol 2004 173: 92-99. [Abstract] [Full Text] [PDF]  

Dysregulated FcRI Signaling and Altered Fyn and SHIP Activities in Lyn-Deficient Mast Cells

Valerie Hernandez-Hansen, Alexander J. Smith, Zurab Surviladze, Alexandre Chigaev, Tomas Mazel, Janet Kalesnikoff, Clifford A. Lowell, Gerald Krystal, Larry A. Sklar, Bridget S. Wilson, and Janet M. Oliver
J Immunol 2004 173: 100-112. [Abstract] [Full Text] [PDF]  

Lymphomagenesis, Hydronephrosis, and Autoantibodies Result from Dysregulation of IL-9 and Are Differentially Dependent on Th2 Cytokines

Angus J. Lauder, Helen E. Jolin, Philippa Smith, José G. van den Berg, Alison Jones, William Wisden, Kenneth G. C. Smith, Ayan Dasvarma, Padraic G. Fallon, and Andrew N. J. McKenzie
J Immunol 2004 173: 113-122. [Abstract] [Full Text] [PDF]  

Cooperative Prosurvival Activity by ERK and Akt in Human Alveolar Macrophages is Dependent on High Levels of Acid Ceramidase Activity

Martha M. Monick, Rama K. Mallampalli, Mary Bradford, Diann McCoy, Thomas J. Gross, Dawn M. Flaherty, Linda S. Powers, Kelli Cameron, Samuel Kelly, Alfred H. Merrill, Jr., and Gary W. Hunninghake
J Immunol 2004 173: 123-135. [Abstract] [Full Text] [PDF]  

An IL-12-Independent Role for CD40-CD154 in Mediating Effector Responses: Studies in Cell-Mediated Glomerulonephritis and Dermal Delayed-Type Hypersensitivity

Amanda-Jane Ruth, A. Richard Kitching, Ming Li, Timothy J. Semple, Jennifer R. Timoshanko, Peter G. Tipping, and Stephen R. Holdsworth
J Immunol 2004 173: 136-144. [Abstract] [Full Text] [PDF]  

A Novel Therapy of Murine Collagen-Induced Arthritis with Soluble T1/ST2

Bernard P. Leung, Damo Xu, Shauna Culshaw, Iain B. McInnes, and Foo Y. Liew
J Immunol 2004 173: 145-150. [Abstract] [Full Text] [PDF]  

Inducing Experimental Arthritis and Breaking Self-Tolerance to Joint-Specific Antigens with Trackable, Ovalbumin-Specific T Cells

Pasquale Maffia, James M. Brewer, J. Alastair Gracie, Angela Ianaro, Bernard P. Leung, Paul J. Mitchell, Karen M. Smith, Iain B. McInnes, and Paul Garside
J Immunol 2004 173: 151-156. [Abstract] [Full Text] [PDF]  

The Diabetes Susceptibility Locus Idd5.1 on Mouse Chromosome 1 Regulates ICOS Expression and Modulates Murine Experimental Autoimmune Encephalomyelitis

Bernhard Greve, Lalitha Vijayakrishnan, Aarup Kubal, Raymond A. Sobel, Laurence B. Peterson, Linda S. Wicker, and Vijay K. Kuchroo
J Immunol 2004 173: 157-163. [Abstract] [Full Text] [PDF]  

Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses Support Ctla4 and Nramp1 as Candidates for Idd5.1 and Idd5.2 in the Nonobese Diabetic Mouse

Linda S. Wicker, Giselle Chamberlain, Kara Hunter, Dan Rainbow, Sarah Howlett, Paul Tiffen, Jan Clark, Andrea Gonzalez-Munoz, Anne Marie Cumiskey, Raymond L. Rosa, Joanna M. Howson, Luc J. Smink, Amanda Kingsnorth, Paul A. Lyons, Simon Gregory, Jane Rogers, John A. Todd, and Laurence B. Peterson
J Immunol 2004 173: 164-173. [Abstract] [Full Text] [PDF]  

NK Cells Stimulate Proliferation of T and NK Cells through 2B4/CD48 Interactions

Erika Assarsson, Taku Kambayashi, John D. Schatzle, Sven O. Cramer, Arne von Bonin, Peter E. Jensen, Hans-Gustaf Ljunggren, and Benedict J. Chambers
J Immunol 2004 173: 174-180. [Abstract] [Full Text] [PDF]  

The Regulatory C-Terminal Determinants within Mycobacterial Heat Shock Protein 65 Are Cryptic and Cross-Reactive with the Dominant Self Homologs: Implications for the Pathogenesis of Autoimmune Arthritis

Malarvizhi Durai, Hong Ro Kim, and Kamal D. Moudgil
J Immunol 2004 173: 181-188. [Abstract] [Full Text] [PDF]  

Distinct Maturation of, but Not Migration between, Human Monocyte-Derived Dendritic Cells upon Ingestion of Apoptotic Cells of Early or Late Phases

Wai-Kee Ip and Yu-Lung Lau
J Immunol 2004 173: 189-196. [Abstract] [Full Text] [PDF]  

Maintenance of Peritoneal B-1a Lymphocytes in the Absence of the Spleen

Karsten Kretschmer, Jana Stopkowicz, Stephan Scheffer, Tim F. Greten, and Siegfried Weiss
J Immunol 2004 173: 197-204. [Abstract] [Full Text] [PDF]  

Mouse Complement Receptor-Related Gene y/p65-Neutralized Tumor Vaccine Induces Antitumor Activity In Vivo

Rieko Ohta, Natalie Kondor, Natsuki Dohi, Stephen Tomlinson, Masaki Imai, V. Michael Holers, Hidechika Okada, and Noriko Okada
J Immunol 2004 173: 205-213. [Abstract] [Full Text] [PDF]  

Different Costimulatory and Growth Factor Requirements for CD4⁺ and CD8⁺ T Cell-Mediated Rejection

Minh Diem Vu, Farhana Amanullah, Yongsheng Li, Gulcin Demirci, Mohamed H. Sayegh, and Xian Chang Li
J Immunol 2004 173: 214-221. [Abstract] [Full Text] [PDF]  

Antigen Distribution Drives Programmed Antitumor CD8 Cell Migration and Determines Its Efficiency

Alexandre Boissonnas, Christophe Combadiere, Elise Lavergne, Maud Maho, Catherine Blanc, Patrice Debré, and Behazine Combadiere
J Immunol 2004 173: 222-229. [Abstract] [Full Text] [PDF]  

Liver Sinusoidal Endothelial Cells Are Insufficient to Activate T Cells

Steven C. Katz, Venu G. Pillarisetty, Joshua I. Bleier, Alaap B. Shah, and Ronald P. DeMatteo
J Immunol 2004 173: 230-235. [Abstract] [Full Text] [PDF]  

CD4⁺ CD25⁺ Regulatory T Cell Repertoire Formation in Response to Varying Expression of a neo-Self-Antigen

Melissa A. Lerman, Joseph Larkin, III, Cristina Cozzo, Martha S. Jordan, and Andrew J. Caton
J Immunol 2004 173: 236-244. [Abstract] [Full Text] [PDF]  

Reduction in the Developmental Potential of Intrathymic T Cell Progenitors with Age

Hyeyoung Min, Encarnacion Montecino-Rodriguez, and Kenneth Dorshkind
J Immunol 2004 173: 245-250. [Abstract] [Full Text] [PDF]  

LIGHT Expression by Mucosal T Cells May Regulate IFN- Expression in the Intestine

Offer Cohavy, Jaclyn Zhou, Steve W. Granger, Carl F. Ware, and Stephan R. Targan
J Immunol 2004 173: 251-258. [Abstract] [Full Text] [PDF]  

Expansion and Contraction of the NK Cell Compartment in Response to Murine Cytomegalovirus Infection

Scott H. Robbins, Marlowe S. Tessmer, Toshifumi Mikayama, and Laurent Brossay
J Immunol 2004 173: 259-266. [Abstract] [Full Text] [PDF]  

Differential Regulatory Capacity of CD25⁺ T Regulatory Cells and Preactivated CD25⁺ T Regulatory Cells on Development, Functional Activation, and Proliferation of Th2 Cells

Michael Stassen, Helmut Jonuleit, Christian Müller, Matthias Klein, Christoph Richter, Tobias Bopp, Steffen Schmitt, and Edgar Schmitt
J Immunol 2004 173: 267-274. [Abstract] [Full Text] [PDF]  

Alteration of Cell Surface Sialylation Regulates Antigen-Induced Naive CD8⁺ T Cell Responses

Bhanu P. Pappu and Protul A. Shrikant
J Immunol 2004 173: 275-284. [Abstract] [Full Text] [PDF]  

Fas-Mediated Apoptosome Formation Is Dependent on Reactive Oxygen Species Derived from Mitochondrial Permeability Transition in Jurkat Cells

Tsutomu Sato, Takuro Machida, Sho Takahashi, Satoshi Iyama, Yasushi Sato, Kageaki Kuribayashi, Kohichi Takada, Takatomi Oku, Yutaka Kawano, Tetsuro Okamoto, Rishu Takimoto, Takuya Matsunaga, Tetsuji Takayama, Minoru Takahashi, Junji Kato, and Yoshiro Niitsu
J Immunol 2004 173: 285-296. [Abstract] [Full Text] [PDF]  

Deficiency of CD11b or CD11d Results in Reduced Staphylococcal Enterotoxin-Induced T Cell Response and T Cell Phenotypic Changes

Huaizhu Wu, John R. Rodgers, Xiao-Yuan Dai Perrard, Jerry L. Perrard, Joseph E. Prince, Yasunori Abe, Beckley K. Davis, Greg Dietsch, C. Wayne Smith, and Christie M. Ballantyne
J Immunol 2004 173: 297-306. [Abstract] [Full Text] [PDF]  

High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization

Davorka Messmer, Huan Yang, Gloria Telusma, Faye Knoll, Jianhua Li, Bradley Messmer, Kevin J. Tracey, and Nicholas Chiorazzi
J Immunol 2004 173: 307-313. [Abstract] [Full Text] [PDF]  

CCR5 Regulates High Dose Oral Tolerance by Modulating CC Chemokine Ligand 2 Levels in the GALT

R. William DePaolo, Rashida Lathan, and William J. Karpus
J Immunol 2004 173: 314-320. [Abstract] [Full Text] [PDF]  

Epstein-Barr Virus Promotes Human Monocyte Survival and Maturation through a Paracrine Induction of IFN-

Shahram Salek-Ardakani, Stephen A. Lyons, and John R. Arrand
J Immunol 2004 173: 321-331. [Abstract] [Full Text] [PDF]  

Monomeric IgG in Intravenous Ig Preparations Is a Functional Antagonist of FcRII and FcRIIIb

Edwin van Mirre, Jessica L. Teeling, Jos W. M. van der Meer, Wim K. Bleeker, and C. Erik Hack
J Immunol 2004 173: 332-339. [Abstract] [Full Text] [PDF]  

Sustained Early Growth Response Gene 3 Expression Inhibits the Survival of CD4/CD8 Double-Positive Thymocytes

Hongkang Xi and Gilbert J. Kersh
J Immunol 2004 173: 340-348. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Structural and Functional Characterization of Complement C4 and C1s-Like Molecules in Teleost Fish: Insights into the Evolution of Classical and Alternative Pathways

Hani Boshra, Andrew E. Gelman, and J. Oriol Sunyer
J Immunol 2004 173: 349-359. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide-Induced Macrophage Inflammatory Response Is Regulated by SHIP

Huiqing Fang, Ruma A. Pengal, Xianhua Cao, Latha P. Ganesan, Mark D. Wewers, Clay B. Marsh, and Susheela Tridandapani
J Immunol 2004 173: 360-366. [Abstract] [Full Text] [PDF]  

Human Complement Factor I Does Not Require Cofactors for Cleavage of Synthetic Substrates

Stefanos A. Tsiftsoglou and Robert B. Sim
J Immunol 2004 173: 367-375. [Abstract] [Full Text] [PDF]  

Serine Residues 286, 288, and 293 within the CIITA: A Mechanism for Down-Regulating CIITA Activity through Phosphorylation

Susanna F. Greer, Jonathan A. Harton, Michael W. Linhoff, Christin A. Janczak, Jenny P.-Y. Ting, and Drew E. Cressman
J Immunol 2004 173: 376-383. [Abstract] [Full Text] [PDF]  

Constitutive and Ligand-Induced TCR Degradation

Marina von Essen, Charlotte Menné Bonefeld, Volkert Siersma, Anette Bødker Rasmussen, Jens Peter H. Lauritsen, Bodil L. Nielsen, and Carsten Geisler
J Immunol 2004 173: 384-393. [Abstract] [Full Text] [PDF]  

Generation of Peptide Mimics of the Epitope Recognized by Trastuzumab on the Oncogenic Protein Her-2/neu

Angelika B. Riemer, Markus Klinger, Stefan Wagner, Astrid Bernhaus, Luca Mazzucchelli, Hubert Pehamberger, Otto Scheiner, Christoph C. Zielinski, and Erika Jensen-Jarolim
J Immunol 2004 173: 394-401. [Abstract] [Full Text] [PDF]  

The Structure of H-2K^b and K^bm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance

Andrew I. Webb, Natalie A. Borg, Michelle A. Dunstone, Lars Kjer-Nielsen, Travis Beddoe, James McCluskey, Francis R. Carbone, Stephen P. Bottomley, Marie-Isabel Aguilar, Anthony W. Purcell, and Jamie Rossjohn
J Immunol 2004 173: 402-409. [Abstract] [Full Text] [PDF]  

A Hierarchy of Nuclear Localization Signals Governs the Import of the Regulatory Factor X Complex Subunits and MHC Class II Expression

Uma M. Nagarajan, Alyssa B. Long, Michelle T. Harreman, Anita H. Corbett, and Jeremy M. Boss
J Immunol 2004 173: 410-419. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Listeria monocytogenes as a Vaccine Vector: Virulence Attenuation or Existing Antivector Immunity Does Not Diminish Therapeutic Efficacy

Holly Starks, Kevin W. Bruhn, Hao Shen, Ronald A. Barry, Thomas W. Dubensky, Dirk Brockstedt, David J. Hinrichs, Darren E. Higgins, Jeffrey F. Miller, Martin Giedlin, and H. G. Archie Bouwer
J Immunol 2004 173: 420-427. [Abstract] [Full Text] [PDF]  

Identification of Neutrophil Granule Protein Cathepsin G as a Novel Chemotactic Agonist for the G Protein-Coupled Formyl Peptide Receptor

Ronghua Sun, Pablo Iribarren, Ning Zhang, Ye Zhou, Wanghua Gong, Edward H. Cho, Stephen Lockett, Oleg Chertov, Filip Bednar, Thomas J. Rogers, Joost J. Oppenheim, and Ji Ming Wang
J Immunol 2004 173: 428-436. [Abstract] [Full Text] [PDF]  

The Major Surface Protein of Wolbachia Endosymbionts in Filarial Nematodes Elicits Immune Responses through TLR2 and TLR4

Norbert W. Brattig, Chiara Bazzocchi, Carsten J. Kirschning, Norbert Reiling, Dietrich W. Büttner, Fabrizio Ceciliani, Frank Geisinger, Hubertus Hochrein, Martin Ernst, Hermann Wagner, Claudio Bandi, and Achim Hoerauf
J Immunol 2004 173: 437-445. [Abstract] [Full Text] [PDF]  

Incomplete Humoral Immunity against Hepatitis C Virus Is Linked with Distinct Recognition of Putative Multiple Receptors by E2 Envelope Glycoprotein

Tae-Hwe Heo, Jae-Hoon Chang, Jae-Woo Lee, Steven K. H. Foung, Jean Dubuisson, and Chang-Yuil Kang
J Immunol 2004 173: 446-455. [Abstract] [Full Text] [PDF]  

The Rapidity with Which Virus-Specific CD8⁺ T Cells Initiate IFN- Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance

Fei Liu, J. Lindsay Whitton, and Mark K. Slifka
J Immunol 2004 173: 456-462. [Abstract] [Full Text] [PDF]  

Intercellular Adhesion Molecule 1 Deficiency Leads to Impaired Recruitment of T Lymphocytes and Enhanced Host Susceptibility to Infection with Trypanosoma cruzi

Vladimir Michailowsky, Mara R. N. Celes, Ana P. Marino, Andréa A. Silva, Leda Q. Vieira, Marcos A. Rossi, Ricardo T. Gazzinelli, Joseli Lannes-Vieira, and João S. Silva
J Immunol 2004 173: 463-470. [Abstract] [Full Text] [PDF]  

Dual Roles of PspC, a Surface Protein of Streptococcus pneumoniae, in Binding Human Secretory IgA and Factor H

Sandhya Dave, Stephanie Carmicle, Sven Hammerschmidt, Michael K. Pangburn, and Larry S. McDaniel
J Immunol 2004 173: 471-477. [Abstract] [Full Text] [PDF]  

Origin and Fate of Lymphocytic Choriomeningitis Virus-Specific CD8⁺ T Cells Coexpressing the Inhibitory NK Cell Receptor Ly49G2

Craig D. Peacock and Raymond M. Welsh
J Immunol 2004 173: 478-484. [Abstract] [Full Text] [PDF]  

Differential Gene Expression Identifies Novel Markers of CD4⁺ and CD8⁺ T Cell Activation Following Stimulation by Mycobacterium tuberculosis

Jacqueline M. Cliff, Iryna N. J. Andrade, Rohit Mistry, Christopher L. Clayton, Mark G. Lennon, Alan P. Lewis, Ken Duncan, Pauline T. Lukey, and Hazel M. Dockrell
J Immunol 2004 173: 485-493. [Abstract] [Full Text] [PDF] Data Supplement  

Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis

Simeone Marino, Santosh Pawar, Craig L. Fuller, Todd A. Reinhart, JoAnne L. Flynn, and Denise E. Kirschner
J Immunol 2004 173: 494-506. [Abstract] [Full Text] [PDF]  

The Low Molecular Weight GTPase RhoA and Atypical Protein Kinase C Are Required for TLR2-Mediated Gene Transcription

Nicole Teusch, Eleuterio Lombardo, Jane Eddleston, and Ulla G. Knaus
J Immunol 2004 173: 507-514. [Abstract] [Full Text] [PDF]  

Activity of - and -Defensins against Primary Isolates of HIV-1

Wei Wang, Sherry M. Owen, Donna L. Rudolph, Alexander M. Cole, Teresa Hong, Alan J. Waring, Renu B. Lal, and Robert I. Lehrer
J Immunol 2004 173: 515-520. [Abstract] [Full Text] [PDF]  

High Bactericidal Efficiency of Type IIA Phospholipase A₂ against Bacillus anthracis and Inhibition of Its Secretion by the Lethal Toxin

Alejandro Piris Gimenez, Yong-Zheng Wu, Miguel Paya, Christophe Delclaux, Lhousseine Touqui, and Pierre L. Goossens
J Immunol 2004 173: 521-530. [Abstract] [Full Text] [PDF]  

TLR3-, TLR7-, and TLR9-Mediated Production of Proinflammatory Cytokines and Chemokines from Murine Connective Tissue Type Skin-Derived Mast Cells but Not from Bone Marrow-Derived Mast Cells

Hironori Matsushima, Nobuo Yamada, Hiroyuki Matsue, and Shinji Shimada
J Immunol 2004 173: 531-541. [Abstract] [Full Text] [PDF]  

Double Mechanism for Apical Tryptophan Depletion in Polarized Human Bronchial Epithelium

Olga Zegarra-Moran, Chiara Folli, Benedetta Manzari, Roberto Ravazzolo, Luigi Varesio, and Luis J. V. Galietta
J Immunol 2004 173: 542-549. [Abstract] [Full Text] [PDF]  

The Hybrid Cytomegalovirus Enhancer/Chicken -Actin Promoter along with Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances the Protective Efficacy of DNA Vaccines

Sanjay Garg, Alp E. Oran, Huiming Hon, and Joshy Jacob
J Immunol 2004 173: 550-558. [Abstract] [Full Text] [PDF]  

Prostaglandin E₂ Inhibits Alveolar Macrophage Phagocytosis through an E-Prostanoid 2 Receptor-Mediated Increase in Intracellular Cyclic AMP

David M. Aronoff, Claudio Canetti, and Marc Peters-Golden
J Immunol 2004 173: 559-565. [Abstract] [Full Text] [PDF]  

Phosphatidylserine Receptor-Mediated Recognition of Archaeosome Adjuvant Promotes Endocytosis and MHC Class I Cross-Presentation of the Entrapped Antigen by Phagosome-to-Cytosol Transport and Classical Processing

Komal Gurnani, Jessica Kennedy, Subash Sad, G. Dennis Sprott, and Lakshmi Krishnan
J Immunol 2004 173: 566-578. [Abstract] [Full Text] [PDF]  

Increase in Hepatic NKT Cells in Leukocyte Cell-Derived Chemotaxin 2-Deficient Mice Contributes to Severe Concanavalin A-Induced Hepatitis

Takeshi Saito, Akinori Okumura, Hisami Watanabe, Masahide Asano, Akiko Ishida-Okawara, Junko Sakagami, Katsuko Sudo, Yoshimi Hatano-Yokoe, Jelena S. Bezbradica, Sebastian Joyce, Toru Abo, Yoichiro Iwakura, Kazuo Suzuki, and Satoshi Yamagoe
J Immunol 2004 173: 579-585. [Abstract] [Full Text] [PDF]  

Helicobacter pylori Arginase Inhibits T Cell Proliferation and Reduces the Expression of the TCR -Chain (CD3)

Jovanny Zabaleta, David J. McGee, Arnold H. Zea, Claudia P. Hernández, Paulo C. Rodriguez, Rosa A. Sierra, Pelayo Correa, and Augusto C. Ochoa
J Immunol 2004 173: 586-593. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Proinflammatory Chemokines, Such as C-C Chemokine Ligand 3, Desensitize µ-Opioid Receptors on Dorsal Root Ganglia Neurons

Ning Zhang, Thomas J. Rogers, Michael Caterina, and Joost J. Oppenheim
J Immunol 2004 173: 594-599. [Abstract] [Full Text] [PDF]  

A Structurally Available Encephalitogenic Epitope of Myelin Oligodendrocyte Glycoprotein Specifically Induces a Diversified Pathogenic Autoimmune Response

Felix Bischof, Adriaan Bins, Michael Dürr, Yinka Zevering, Arthur Melms, and Ada M. Kruisbeek
J Immunol 2004 173: 600-606. [Abstract] [Full Text] [PDF]  

Identification of Peptides That Antagonize Formyl Peptide Receptor-Like 1-Mediated Signaling

Yoe-Sik Bae, Ha Young Lee, Eun Jin Jo, Jung Im Kim, Hyun-Kyu Kang, Richard D. Ye, Jong-Young Kwak, and Sung Ho Ryu
J Immunol 2004 173: 607-614. [Abstract] [Full Text] [PDF]  

Regulation of Cockroach Antigen-Induced Allergic Airway Hyperreactivity by the CXCR3 Ligand CXCL9

Molly S. Thomas, Steven L. Kunkel, and Nicholas W. Lukacs
J Immunol 2004 173: 615-623. [Abstract] [Full Text] [PDF]  

Rac and Protein Kinase C- Regulate ERKs and Cytosolic Phospholipase A₂ in FcRI Signaling to Cysteinyl Leukotriene Synthesis in Mast Cells

Sung-Hoon Cho, Hye-Jin You, Chang-Hoon Woo, Yung-Joon Yoo, and Jae-Hong Kim
J Immunol 2004 173: 624-631. [Abstract] [Full Text] [PDF]  

Requirement for CD28 in the Effector Phase of Allergic Airway Inflammation

Stephanie L. Kimzey, Pingfan Liu, and Jonathan M. Green
J Immunol 2004 173: 632-640. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Abundant Expression of Granzyme A, but Not Perforin, in Granules of CD8⁺ T Cells in GALT: Implications for Immune Control of HIV-1 Infection

Barbara L. Shacklett, Catherine A. Cox, Máire F. Quigley, Christophe Kreis, Neil H. Stollman, Mark A. Jacobson, Jan Andersson, Johan K. Sandberg, and Douglas F. Nixon
J Immunol 2004 173: 641-648. [Abstract] [Full Text] [PDF]  

Comparative Analysis of the CD19⁺ and CD138⁺ Cell Antibody Repertoires in the Cerebrospinal Fluid of Patients with Multiple Sclerosis

Alanna M. Ritchie, Donald H. Gilden, R. Anthony Williamson, Mark P. Burgoon, Xiaoli Yu, Karen Helm, John R. Corboy, and Gregory P. Owens
J Immunol 2004 173: 649-656. [Abstract] [Full Text] [PDF]  

Distinct Activation Signals Determine whether IL-21 Induces B Cell Costimulation, Growth Arrest, or Bim-Dependent Apoptosis

Haoli Jin, Roberto Carrio, Aixin Yu, and Thomas R. Malek
J Immunol 2004 173: 657-665. [Abstract] [Full Text] [PDF]  

Evidence That Invasion-Inhibitory Antibodies Specific for the 19-kDa Fragment of Merozoite Surface Protein-1 (MSP-1₁₉) Can Play a Protective Role against Blood-Stage Plasmodium falciparum Infection in Individuals in a Malaria Endemic Area of Africa

Chandy C. John, Rebecca A. O’Donnell, Peter O. Sumba, Ann M. Moormann, Tania F. de Koning-Ward, Christopher L. King, James W. Kazura, and Brendan S. Crabb
J Immunol 2004 173: 666-672. [Abstract] [Full Text] [PDF]  

Age-Associated Change in the Frequency of Memory CD4⁺ T Cells Impairs Long Term CD4⁺ T Cell Responses to Influenza Vaccine

Insoo Kang, Myung Sun Hong, Helena Nolasco, Sung Hwan Park, Jin Myung Dan, Jin-Young Choi, and Joe Craft
J Immunol 2004 173: 673-681. [Abstract] [Full Text] [PDF]  

T Cells Enhance the Expression of Experimental Autoimmune Encephalomyelitis by Promoting Antigen Presentation and IL-12 Production

Artur Odyniec, Marian Szczepanik, Marcin P. Mycko, Mariusz Stasiolek, Cedric S. Raine, and Krzysztof W. Selmaj
J Immunol 2004 173: 682-694. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3 Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated into One Combined CD28/CD3 Signaling Receptor Molecule

Andreas Hombach, Anja Wieczarkowiecz, Thomas Marquardt, Claudia Heuser, Loretta Usai, Christoph Pohl, Barbara Seliger, and Hinrich Abken
J Immunol 2004 173: 695. [Full Text] [PDF]  

B Cell Developmental Requirement for the Gi2 Gene

Harnisha Dalwadi, Bo Wei, Matthew Schrage, Karsten Spicher, Tom T. Su, Lutz Birnbaumer, David J. Rawlings, and Jonathan Braun
J Immunol 2004 173: 695. [Full Text] [PDF]  

Dendritic Cell-Induced Activation of Adaptive and Innate Antitumor Immunity

Leon T. van den Broeke, Emily Daschbach, Elaine K. Thomas, Gerda Andringa, and Jay A. Berzofsky
J Immunol 2004 173: 695. [Full Text] [PDF]  

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