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On the cover: SCID mice transferred CD45RBhigh T cells and cotransferred T cells bearing TGF-1 (LAP+) do not develop bowel inflammation. This implies that regulatory cells present in CD45RBlow cell populations bear surface TGF-1. Nakamura et al. TGF-1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J. Immunol. 172:834.

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