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On the cover: Normal donor-derived cells (red) in thymuses from bone marrow chimeras are distributed throughout cortical and medullary regions (distinguished by the morphology of stromal cells, green). In the absence of CXCR4 on thymocytes, donor cells home to the thymus but fail to distribute normally. Plotkin et al. Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus. J. Immunol. 171:4521.