IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2003 171: 5649-5650. [Full Text] [PDF]  

LETTERS TO THE EDITOR:

LETTERS TO THE EDITOR

Johannes Roth, Thomas Vogl, Cord Sunderkötter, and Clemens Sorg
J Immunol 2003 171: 5651. [Full Text] [PDF]  

BRIEF REVIEWS:

Early T Lineage Progenitors: New Insights, but Old Questions Remain

Avinash Bhandoola, Arivazhagan Sambandam, David Allman, Anita Meraz, and Benjamin Schwarz
J Immunol 2003 171: 5653-5658. [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: SDS-Stable Fas Microaggregates: An Early Event of Fas Activation Occurring with Agonistic Anti-Fas Antibody but Not with Fas Ligand

Patrick Legembre, Marie Beneteau, Sophie Daburon, Jean-François Moreau, and Jean-Luc Taupin
J Immunol 2003 171: 5659-5662. [Abstract] [Full Text] [PDF]  

Cutting Edge: Increased NK Cell Activity in HIV-1-Exposed but Uninfected Vietnamese Intravascular Drug Users

Daniel Scott-Algara, Lien X. Truong, Pierre Versmisse, Annie David, Tram T. Luong, Ngai V. Nguyen, Ioannis Theodorou, Françoise Barré-Sinoussi, and Gianfranco Pancino
J Immunol 2003 171: 5663-5667. [Abstract] [Full Text] [PDF]  

Cutting Edge: Efficient MHC Class I Cross-Presentation during Early Vaccinia Infection Requires the Transfer of Proteasomal Intermediates between Antigen Donor and Presenting Cells

Amparo Serna, Maria C. Ramirez, Anna Soukhanova, and Luis J. Sigal
J Immunol 2003 171: 5668-5672. [Abstract] [Full Text] [PDF]  

Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression

Charlotte Ariyan, Paolo Salvalaggio, Scott Fecteau, Songyan Deng, Linda Rogozinski, Didier Mandelbrot, Arlene Sharpe, Mohamed H. Sayegh, Giacomo P. Basadonna, and David M. Rothstein
J Immunol 2003 171: 5673-5677. [Abstract] [Full Text] [PDF]  

Cutting Edge: Self-Peptides Drive the Peripheral Expansion of CD4⁺CD25⁺ Regulatory T Cells

Cristina Cozzo, Joseph Larkin, III, and Andrew J. Caton
J Immunol 2003 171: 5678-5682. [Abstract] [Full Text] [PDF]  

Cutting Edge: TCR Contacts as Anchors: Effects on Affinity and HLA-DM Stability

Matthew W. Anderson and Jack Gorski
J Immunol 2003 171: 5683-5687. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Requirements for T Cell-Polarized Tubulation of Class II⁺ Compartments in Dendritic Cells

Nicolas Bertho, Jan Cerny, You-Me Kim, Edda Fiebiger, Hidde Ploegh, and Marianne Boes
J Immunol 2003 171: 5689-5696. [Abstract] [Full Text] [PDF]  

CD4⁺ T Cell-Associated Pathophysiology Critically Depends on CD18 Gene Dose Effects in a Murine Model of Psoriasis

Daniel Kess, Thorsten Peters, Jan Zamek, Claudia Wickenhauser, Samir Tawadros, Karin Loser, Georg Varga, Stephan Grabbe, Roswitha Nischt, Cord Sunderkötter, Werner Müller, Thomas Krieg, and Karin Scharffetter-Kochanek
J Immunol 2003 171: 5697-5706. [Abstract] [Full Text] [PDF]  

CD40, but Not CD154, Expression on B Cells Is Necessary for Optimal Primary B Cell Responses

Byung O. Lee, Juan Moyron-Quiroz, Javier Rangel-Moreno, Kim L. Kusser, Louise Hartson, Frank Sprague, Frances E. Lund, and Troy D. Randall
J Immunol 2003 171: 5707-5717. [Abstract] [Full Text] [PDF]  

Tethering of Apoptotic Cells to Phagocytes through Binding of CD47 to Src Homology 2 Domain-Bearing Protein Tyrosine Phosphatase Substrate-1

Kazutoshi Tada, Masato Tanaka, Rikinari Hanayama, Keiko Miwa, Azusa Shinohara, Akihiro Iwamatsu, and Shigekazu Nagata
J Immunol 2003 171: 5718-5726. [Abstract] [Full Text] [PDF]  

IL-2 Is Not Required for the Initiation of CD8 T Cell Cycling but Sustains Expansion

Warren N. D’Souza and Leo Lefrançois
J Immunol 2003 171: 5727-5735. [Abstract] [Full Text] [PDF]  

Aberrant Extracellular and Dendritic Cell (DC) Surface Expression of Heat Shock Protein (hsp)70 in the Rheumatoid Joint: Possible Mechanisms of hsp/DC-Mediated Cross-Priming

Carla A. Martin, Steven E. Carsons, Robert Kowalewski, David Bernstein, Michael Valentino, and Frances Santiago-Schwarz
J Immunol 2003 171: 5736-5742. [Abstract] [Full Text] [PDF]  

Peroxisome Proliferator-Activated Receptor--Deficient Heterozygous Mice Develop an Exacerbated Neural Antigen-Induced Th1 Response and Experimental Allergic Encephalomyelitis

John J. Bright, Chandramohan Natarajan, Gladson Muthian, Yaavov Barak, and Ronald M. Evans
J Immunol 2003 171: 5743-5750. [Abstract] [Full Text] [PDF]  

TNF Receptor-Associated Factor 6 Deficiency during Hemopoiesis Induces Th2-Polarized Inflammatory Disease

Elise Chiffoleau, Takashi Kobayashi, Matthew C. Walsh, Carolyn G. King, Patrick T. Walsh, Wayne W. Hancock, Yongwon Choi, and Laurence A. Turka
J Immunol 2003 171: 5751-5759. [Abstract] [Full Text] [PDF]  

Human CD25⁺ Regulatory T Cells Maintain Immune Tolerance to Nickel in Healthy, Nonallergic Individuals

Andrea Cavani, Francesca Nasorri, Chiara Ottaviani, Silvia Sebastiani, Ornella De Pità, and Giampiero Girolomoni
J Immunol 2003 171: 5760-5768. [Abstract] [Full Text] [PDF]  

In Vitro Differentiation from Naive to Mature E-Selectin Binding CD4 T Cells: Acquisition of Skin-Homing Properties Occurs Independently of Cutaneous Lymphocyte Antigen Expression

Ryo Takahashi, Yoshiko Mizukawa, Yoshimi Yamazaki, Kazuhito Hayakawa, Jun Hayakawa, Akihiko Kudo, and Tetsuo Shiohara
J Immunol 2003 171: 5769-5777. [Abstract] [Full Text] [PDF]  

Ultraviolet B Radiation-Induced Cell Death: Critical Role of Ultraviolet Dose in Inflammation and Lupus Autoantigen Redistribution

Roberto Caricchio, Lenese McPhie, and Philip L. Cohen
J Immunol 2003 171: 5778-5786. [Abstract] [Full Text] [PDF]  

Human ErbB-2 (Her-2) Transgenic Mice: A Model System for Testing Her-2 Based Vaccines

Marie P. Piechocki, Ye-Shih Ho, Shari Pilon, and Wei-Zen Wei
J Immunol 2003 171: 5787-5794. [Abstract] [Full Text] [PDF]  

Increased Severity of Murine Lupus in Female Mice Is Due to Enhanced Expansion of Pathogenic T Cells

Thomas J. Lang, Phuong Nguyen, John C. Papadimitriou, and Charles S. Via
J Immunol 2003 171: 5795-5801. [Abstract] [Full Text] [PDF]  

Role of Antiproliferative B Cell Translocation Gene-1 as an Apoptotic Sensitizer in Activation-Induced Cell Death of Brain Microglia

Heasuk Lee, Sanghoon Cha, Myung-Shik Lee, Gyeong Jae Cho, Wan Sung Choi, and Kyoungho Suk
J Immunol 2003 171: 5802-5811. [Abstract] [Full Text] [PDF]  

MHC Class II-Peptide Complexes in Dendritic Cell Lipid Microdomains Initiate the CD4 Th1 Phenotype

Vanessa Buatois, Marjorie Baillet, Stéphane Bécart, Nuala Mooney, Lee Leserman, and Patrick Machy
J Immunol 2003 171: 5812-5819. [Abstract] [Full Text] [PDF]  

Estradiol Treatment Redirects the Isotype of the Autoantibody Response and Prevents the Development of Autoimmune Arthritis

Kary A. Latham, Alex Zamora, Heather Drought, Sandhya Subramanian, Agata Matejuk, Halina Offner, and Edward F. Rosloniec
J Immunol 2003 171: 5820-5827. [Abstract] [Full Text] [PDF]  

The Duration of Signaling through CD40 Directs Biological Ability of Dendritic Cells to Induce Antitumor Immunity

Satoshi Watanabe, Hiroshi Kagamu, Hirohisa Yoshizawa, Nanae Fujita, Hiroshi Tanaka, Junta Tanaka, and Fumitake Gejyo
J Immunol 2003 171: 5828-5836. [Abstract] [Full Text] [PDF]  

Maturation of Dendritic Cell 2 Phenotype by a Helminth Glycan Uses a Toll-Like Receptor 4-Dependent Mechanism

Paul G. Thomas, Michele R. Carter, Olga Atochina, Akram A. Da’Dara, Danuta Piskorska, Edward McGuire, and Donald A. Harn
J Immunol 2003 171: 5837-5841. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Induced Activation of Adaptive and Innate Antitumor Immunity

Leon T. van den Broeke, Emily Daschbach, Elaine K. Thomas, Gerda Andringa, and Jay A. Berzofsky
J Immunol 2003 171: 5842-5852. [Abstract] [Full Text] [PDF]  

Distinct Effects of STAT5 Activation on CD4⁺ and CD8⁺ T Cell Homeostasis: Development of CD4⁺CD25⁺ Regulatory T Cells versus CD8⁺ Memory T Cells

Matthew A. Burchill, Christine A. Goetz, Martin Prlic, Jennifer J. O’Neil, Ian R. Harmon, Steven J. Bensinger, Laurence A. Turka, Paul Brennan, Stephen C. Jameson, and Michael A. Farrar
J Immunol 2003 171: 5853-5864. [Abstract] [Full Text] [PDF]  

Systemic Administration of IL-18 Promotes Diabetes Development in Young Nonobese Diabetic Mice

Yoichi Oikawa, Akira Shimada, Akira Kasuga, Jiro Morimoto, Tadashi Osaki, Hideaki Tahara, Tatsushi Miyazaki, Fumi Tashiro, Eiji Yamato, Jun-ichi Miyazaki, and Takao Saruta
J Immunol 2003 171: 5865-5875. [Abstract] [Full Text] [PDF]  

Ligation of CD27 on B Cells In Vivo during Primary Immunization Enhances Commitment to Memory B Cell Responses

Vanitha S. Raman, Rama S. Akondy, Satyajit Rath, Vineeta Bal, and Anna George
J Immunol 2003 171: 5876-5881. [Abstract] [Full Text] [PDF]  

Fibronectin-Associated Fas Ligand Rapidly Induces Opposing and Time-Dependent Effects on the Activation and Apoptosis of T Cells

Alexandra Zanin-Zhorov, Rami Hershkoviz, Iris Hecht, Liora Cahalon, and Ofer Lider
J Immunol 2003 171: 5882-5889. [Abstract] [Full Text] [PDF]  

Tolerance through Indifference: Autoreactive B Cells to the Nuclear Antigen La Show No Evidence of Tolerance in a Transgenic Model

Brett D. Aplin, Catherine L. Keech, Andrea L. de Kauwe, Thomas P. Gordon, Dana Cavill, and James McCluskey
J Immunol 2003 171: 5890-5900. [Abstract] [Full Text] [PDF]  

IL-4 and IL-13 Induce SOCS-1 Gene Expression in A549 Cells by Three Functional STAT6-Binding Motifs Located Upstream of the Transcription Initiation Site

Daniel Hebenstreit, Petra Luft, Angela Schmiedlechner, Gerhard Regl, Anna-Maria Frischauf, Fritz Aberger, Albert Duschl, and Jutta Horejs-Hoeck
J Immunol 2003 171: 5901-5907. [Abstract] [Full Text] [PDF]  

Vaccination with Plasmid DNA Activates Dendritic Cells via Toll-Like Receptor 9 (TLR9) but Functions in TLR9-Deficient Mice

Barbara Spies, Hubertus Hochrein, Martin Vabulas, Katharina Huster, Dirk H. Busch, Frank Schmitz, Antje Heit, and Hermann Wagner
J Immunol 2003 171: 5908-5912. [Abstract] [Full Text] [PDF]  

Control of NKT Cell Differentiation by Tissue-Specific Microenvironments

Yang Yang, Aito Ueno, Min Bao, Zhongying Wang, Jin Seon Im, Steven Porcelli, and Ji-Won Yoon
J Immunol 2003 171: 5913-5920. [Abstract] [Full Text] [PDF]  

CD19 Function in Early and Late B Cell Development. II. CD19 Facilitates the Pro-B/Pre-B Transition

Dennis C. Otero and Robert C. Rickert
J Immunol 2003 171: 5921-5930. [Abstract] [Full Text] [PDF]  

CD4⁺/CD25⁺ Regulatory Cells Inhibit Activation of Tumor-Primed CD4⁺ T Cells with IFN--Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination

Noelia Casares, Laura Arribillaga, Pablo Sarobe, Javier Dotor, Ascensión Lopez-Diaz de Cerio, Ignacio Melero, Jesús Prieto, Francisco Borrás-Cuesta, and Juan J. Lasarte
J Immunol 2003 171: 5931-5939. [Abstract] [Full Text] [PDF]  

Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4⁺ and CD8⁺ T Cell Immunity against B16 Melanoma

Romina S. Goldszmid, Juliana Idoyaga, Alicia I. Bravo, Ralph Steinman, José Mordoh, and Rosa Wainstok
J Immunol 2003 171: 5940-5947. [Abstract] [Full Text] [PDF]  

Promiscuity of MHC Class Ib-Restricted T Cell Responses

Alexander Ploss, Gregoire Lauvau, Brian Contos, Kristen M. Kerksiek, Patrick D. Guirnalda, Ingrid Leiner, Laurel L. Lenz, Michael J. Bevan, and Eric G. Pamer
J Immunol 2003 171: 5948-5955. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Molecular Cloning and Immunologic Characterization of a Novel cDNA Coding for Progesterone-Induced Blocking Factor

Beata Polgar, Gyula Kispal, Margit Lachmann, Gabriella Paar, Eszter Nagy, Peter Csere, Eva Miko, Laszlo Szereday, Peter Varga, and Julia Szekeres-Bartho
J Immunol 2003 171: 5956-5963. [Abstract] [Full Text] [PDF]  

Simultaneous Prediction of Binding Capacity for Multiple Molecules of the HLA B44 Supertype

John Sidney, Scott Southwood, Valerie Pasquetto, and Alessandro Sette
J Immunol 2003 171: 5964-5974. [Abstract] [Full Text] [PDF] Data Supplement  

Altered Regulation of FcRII on Aged Follicular Dendritic Cells Correlates with Immunoreceptor Tyrosine-Based Inhibition Motif Signaling in B Cells and Reduced Germinal Center Formation

Yüksel Aydar, Péter Balogh, John G. Tew, and Andras K. Szakal
J Immunol 2003 171: 5975-5987. [Abstract] [Full Text] [PDF]  

Function of Bruton’s Tyrosine Kinase during B Cell Development Is Partially Independent of Its Catalytic Activity

Sabine Middendorp, Gemma M. Dingjan, Alex Maas, Katarina Dahlenborg, and Rudolf W. Hendriks
J Immunol 2003 171: 5988-5996. [Abstract] [Full Text] [PDF]  

OX40-Mediated Memory T Cell Generation Is TNF Receptor-Associated Factor 2 Dependent

Rodney A. Prell, Dean E. Evans, Colin Thalhofer, Tom Shi, Castle Funatake, and Andrew D. Weinberg
J Immunol 2003 171: 5997-6005. [Abstract] [Full Text] [PDF]  

Ikaros Family Members from the Agnathan Myxine glutinosa and the Urochordate Oikopleura dioica: Emergence of an Essential Transcription Factor for Adaptive Immunity

Pauline M. Cupit, John D. Hansen, Aaron S. McCarty, Greg White, Mariacristina Chioda, Fabio Spada, Stephen T. Smale, and Charles Cunningham
J Immunol 2003 171: 6006-6013. [Abstract] [Full Text] [PDF]  

Inhibition of NF-B Activation and Its Target Genes by Heparin-Binding Epidermal Growth Factor-Like Growth Factor

Veela B. Mehta and Gail E. Besner
J Immunol 2003 171: 6014-6022. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Allogeneic T Cells Treated with Amotosalen Prevent Lethal Cytomegalovirus Disease without Producing Graft-versus-Host Disease Following Bone Marrow Transplantation

John D. Roback, Mohammad S. Hossain, Levan Lezhava, John W. Gorechlad, Sabina A. Alexander, David L. Jaye, Stephen Mittelstaedt, Sohel Talib, John E. Hearst, Christopher D. Hillyer, and Edmund K. Waller
J Immunol 2003 171: 6023-6031. [Abstract] [Full Text] [PDF]  

Activation of Antigen-Specific CD8 T Cells Results in Minimal Killing of Bystander Bacteria

Jiu Jiang, Lauren A. Zenewicz, Lani R. San Mateo, Lisa L. Lau, and Hao Shen
J Immunol 2003 171: 6032-6038. [Abstract] [Full Text] [PDF]  

NK Cells Respond to Pulmonary Infection with Mycobacterium tuberculosis, but Play a Minimal Role in Protection

Ana Paula Junqueira-Kipnis, Andre Kipnis, Amanda Jamieson, Mercedes Gonzalez Juarrero, Andreas Diefenbach, David H. Raulet, Joanne Turner, and Ian M. Orme
J Immunol 2003 171: 6039-6045. [Abstract] [Full Text] [PDF]  

Human C-Reactive Protein Does Not Protect against Acute Lipopolysaccharide Challenge in Mice

Gideon M. Hirschfield, Jeff Herbert, Melvyn C. Kahan, and Mark B. Pepys
J Immunol 2003 171: 6046-6051. [Abstract] [Full Text] [PDF]  

Cross-Talk in the Innate Immune System: Neutrophils Instruct Recruitment and Activation of Dendritic Cells during Microbial Infection

Soumaya Bennouna, Susan K. Bliss, Tyler J. Curiel, and Eric Y. Denkers
J Immunol 2003 171: 6052-6058. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Sustained Nitric Oxide Delivery Delays Nitric Oxide-Dependent Apoptosis in Macrophages: Contribution to the Physiological Function of Activated Macrophages

Sonsoles Hortelano, Paqui G. Través, Miriam Zeini, Alberto M. Alvarez, and Lisardo Boscá
J Immunol 2003 171: 6059-6064. [Abstract] [Full Text] [PDF]  

IL-1R-Associated Kinase 4 Is Required for Lipopolysaccharide- Induced Activation of APC

Nobutaka Suzuki, Shinobu Suzuki, Urs Eriksson, Hiromitsu Hara, Christine Mirtosis, Nien-Jung Chen, Teiji Wada, Denis Bouchard, Irene Hwang, Kiyoshi Takeda, Takashi Fujita, Sandy Der, Josef M. Penninger, Shizuo Akira, Takashi Saito, and Wen-Chen Yeh
J Immunol 2003 171: 6065-6071. [Abstract] [Full Text] [PDF]  

Curcumin Suppresses Janus Kinase-STAT Inflammatory Signaling through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia

Hee Young Kim, Eun Jung Park, Eun-hye Joe, and Ilo Jou
J Immunol 2003 171: 6072-6079. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2-Derived E Prostaglandins Down-Regulate Matrix Metalloproteinase-1 Expression in Fibroblast-Like Synoviocytes via Inhibition of Extracellular Signal-Regulated Kinase Activation

Michael H. Pillinger, Pamela B. Rosenthal, Sonia N. Tolani, Beth Apsel, Victoria Dinsell, Jeffrey Greenberg, Edwin S. L. Chan, Paul F. Gomez, and Steven B. Abramson
J Immunol 2003 171: 6080-6089. [Abstract] [Full Text] [PDF]  

FcRIIIb Allele-Sensitive Release of -Defensins: Anti-Neutrophil Cytoplasmic Antibody-Induced Release of Chemotaxins

Sumiaki Tanaka, Jeffrey C. Edberg, Winn Chatham, Giorgio Fassina, and Robert P. Kimberly
J Immunol 2003 171: 6090-6096. [Abstract] [Full Text] [PDF]  

Activation of Endothelial Extracellular Signal-Regulated Kinase Is Essential for Neutrophil Transmigration: Potential Involvement of a Soluble Neutrophil Factor in Endothelial Activation

Brian N. Stein, Jennifer R. Gamble, Stuart M. Pitson, Mathew A. Vadas, and Yeesim Khew-Goodall
J Immunol 2003 171: 6097-6104. [Abstract] [Full Text] [PDF]  

Mac-1, but Not LFA-1, Uses Intercellular Adhesion Molecule-1 to Mediate Slow Leukocyte Rolling in TNF--Induced Inflammation

Jessica L. Dunne, Robert G. Collins, Arthur L. Beaudet, Christie M. Ballantyne, and Klaus Ley
J Immunol 2003 171: 6105-6111. [Abstract] [Full Text] [PDF]  

Regulation and Phenotype of an Innate Th1 Cell: Role of Cytokines and the p38 Kinase Pathway

Jeffrey J. Yu, Catherine S. Tripp, and John H. Russell
J Immunol 2003 171: 6112-6118. [Abstract] [Full Text] [PDF]  

FcRI Signaling of Mast Cells Activates Intracellular Production of Hydrogen Peroxide: Role in the Regulation of Calcium Signals

Yoshihiro Suzuki, Tetsuro Yoshimaru, Takashi Matsui, Toshio Inoue, Osamu Niide, Satoshi Nunomura, and Chisei Ra
J Immunol 2003 171: 6119-6127. [Abstract] [Full Text] [PDF]  

Increased Acute Inflammation, Leukotriene B₄-Induced Chemotaxis, and Signaling in Mice Deficient for G Protein-Coupled Receptor Kinase 6

Annemieke Kavelaars, Anne Vroon, Roel P. Raatgever, Alan M. Fong, Richard T. Premont, Dhavalkumar D. Patel, Robert J. Lefkowitz, and Cobi J. Heijnen
J Immunol 2003 171: 6128-6134. [Abstract] [Full Text] [PDF]  

Endothelial Cells Proactively Form Microvilli-Like Membrane Projections upon Intercellular Adhesion Molecule 1 Engagement of Leukocyte LFA-1

Christopher V. Carman, Chang-Duk Jun, Azucena Salas, and Timothy A. Springer
J Immunol 2003 171: 6135-6144. [Abstract] [Full Text] [PDF]  

Toll-Like Receptor 2 Pathway Drives Streptococcal Cell Wall-Induced Joint Inflammation: Critical Role of Myeloid Differentiation Factor 88

Leo A. B. Joosten, Marije I. Koenders, Ruben L. Smeets, Marleen Heuvelmans-Jacobs, Monique M. A. Helsen, Kiyoshi Takeda, Shizuo Akira, Erik Lubberts, Fons A. J. van de Loo, and Wim B. van den Berg
J Immunol 2003 171: 6145-6153. [Abstract] [Full Text] [PDF]  

Apoptosis-Associated Speck-Like Protein Containing a Caspase Recruitment Domain Is a Regulator of Procaspase-1 Activation

Christian Stehlik, Sug Hyung Lee, Andrea Dorfleutner, Angela Stassinopoulos, Junji Sagara, and John C. Reed
J Immunol 2003 171: 6154-6163. [Abstract] [Full Text] [PDF]  

Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms

Matthias Bruewer, Andreas Luegering, Torsten Kucharzik, Charles A. Parkos, James L. Madara, Ann M. Hopkins, and Asma Nusrat
J Immunol 2003 171: 6164-6172. [Abstract] [Full Text] [PDF]  

Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice

Susumu Nakae, Aya Nambu, Katsuko Sudo, and Yoichiro Iwakura
J Immunol 2003 171: 6173-6177. [Abstract] [Full Text] [PDF]  

Alterations in Granule Matrix and Cell Surface of Focal Adhesion Kinase-Deficient Mast Cells

Daniel Vial, Constance Oliver, Maria Célia Jamur, Maria Verônica Dávila Pastor, Edvaldo da Silva Trindade, Elsa Berenstein, Juan Zhang, and Reuben P. Siraganian
J Immunol 2003 171: 6178-6186. [Abstract] [Full Text] [PDF]  

Toll-Like Receptor-2, but Not Toll-Like Receptor-4, Is Essential for Development of Oviduct Pathology in Chlamydial Genital Tract Infection

Toni Darville, Joshua M. O’Neill, Charles W. Andrews, Jr., Uma M. Nagarajan, Lynn Stahl, and David M. Ojcius
J Immunol 2003 171: 6187-6197. [Abstract] [Full Text] [PDF]  

Aberrant Inflammation and Lethality to Septic Peritonitis in Mice Lacking STAT3 in Macrophages and Neutrophils

Akihiro Matsukawa, Kiyoshi Takeda, Shinji Kudo, Takako Maeda, Motoko Kagayama, and Shizuo Akira
J Immunol 2003 171: 6198-6205. [Abstract] [Full Text] [PDF]  

Inhibition of Th1- and Th2-Mediated Airway Inflammation by the Sphingosine 1-Phosphate Receptor Agonist FTY720

Elzbieta Sawicka, Claudia Zuany-Amorim, Corinne Manlius, Alexandre Trifilieff, Volker Brinkmann, David M. Kemeny, and Christoph Walker
J Immunol 2003 171: 6206-6214. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Placental Cell Expression of HLA-G2 Isoforms Is Limited to the Invasive Trophoblast Phenotype

Pedro J. Morales, Judith L. Pace, Jeralyn Sue Platt, Teresa A. Phillips, Kim Morgan, Asgi T. Fazleabas, and Joan S. Hunt
J Immunol 2003 171: 6215-6224. [Abstract] [Full Text] [PDF]  

B-1 B Cells Mediate Required Early T Cell Recruitment to Elicit Protein-Induced Delayed-Type Hypersensitivity

Marian Szczepanik, Moe Akahira-Azuma, Krzysztof Bryniarski, Ryohei F. Tsuji, Ivana Kawikova, Wlodzimierz Ptak, Claudia Kiener, Regis A. Campos, and Philip W. Askenase
J Immunol 2003 171: 6225-6235. [Abstract] [Full Text] [PDF]  

Mechanisms of Spontaneous Resolution versus Fibrosis in Granulomatous Experimental Autoimmune Thyroiditis

Kemin Chen, Yongzhong Wei, Gordon C. Sharp, and Helen Braley-Mullen
J Immunol 2003 171: 6236-6243. [Abstract] [Full Text] [PDF]  

The Plant Lectin Wheat Germ Agglutinin Inhibits the Binding of Pemphigus Foliaceus Autoantibodies to Desmoglein 1 in a Majority of Patients and Prevents Pathomechanisms of Pemphigus Foliaceus In Vitro and In Vivo

Susana Ortiz-Urda, Adelheid Elbe-Bürger, Josef Smolle, Yvonne Marquart, Yakov Chudnovsky, Todd W. Ridky, Pamela Bernstein, Klaus Wolff, and Klemens Rappersberger
J Immunol 2003 171: 6244-6250. [Abstract] [Full Text] [PDF]  

Activity and Safety of CTLA-4 Blockade Combined with Vaccines in Cynomolgus Macaques

Tibor Keler, Ed Halk, Laura Vitale, Tom O’Neill, Diann Blanset, Steven Lee, Mohan Srinivasan, Robert F. Graziano, Thomas Davis, Nils Lonberg, and Alan Korman
J Immunol 2003 171: 6251-6259. [Abstract] [Full Text] [PDF]  

Chromatin Specificity of Anti-Double-Stranded DNA Antibodies and a Role for Arg Residues in the Third Complementarity-Determining Region of the Heavy Chain

Amanda M. Guth, Xianghua Zhang, Diana Smith, Thiago Detanico, and Lawrence J. Wysocki
J Immunol 2003 171: 6260-6266. [Abstract] [Full Text] [PDF]  

Immune Modulation in Multiple Sclerosis Patients Treated with the Pregnancy Hormone Estriol

Samantha S. Soldan, Ana Isabel Alvarez Retuerto, Nancy L. Sicotte, and Rhonda R. Voskuhl
J Immunol 2003 171: 6267-6274. [Abstract] [Full Text] [PDF]  

Injection of Immature Dendritic Cells into Adjuvant-Treated Skin Obviates the Need for Ex Vivo Maturation

Smita Nair, Catherine McLaughlin, Alon Weizer, Zhen Su, David Boczkowski, Jens Dannull, Johannes Vieweg, and Eli Gilboa
J Immunol 2003 171: 6275-6282. [Abstract] [Full Text] [PDF]  

Identification of Five New HLA-B*3501-Restricted Epitopes Derived from Common Melanoma-Associated Antigens, Spontaneously Recognized by Tumor-Infiltrating Lymphocytes

Houssem Benlalam, Boris Linard, Yannik Guilloux, Agnès Moreau-Aubry, Laurent Derré, Elisabeth Diez, Brigitte Dreno, Francine Jotereau, and Nathalie Labarrière
J Immunol 2003 171: 6283-6289. [Abstract] [Full Text] [PDF]  

Differential Regulation of Peripheral CD4⁺ T Cell Tolerance Induced by Deletion and TCR Revision

Mohamed Ali, Michael Weinreich, Stephanie Balcaitis, Cristine J. Cooper, and Pamela J. Fink
J Immunol 2003 171: 6290-6296. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

In Vivo Impact of CpG1826 Oligodeoxynucleotide on CD8 T Cell Primary Responses and Survival

Laurent Beloeil, Martine Tomkowiak, Georgi Angelov, Thierry Walzer, Patrice Dubois, and Jacqueline Marvel
J Immunol 2003 171: 6297. [Full Text] [PDF]  

IFN--Induced MHC Class II Expression: Transactivation of Class II Transactivator Promoter IV by IFN Regulatory Factor-1 is Regulated by Protein Kinase C-

Mélanie Giroux, Manuel Schmidt, and Albert Descoteaux
J Immunol 2003 171: 6297. [Full Text] [PDF]  

Dectin-1 Expression and Function Are Enhanced on Alternatively Activated and GM-CSF-Treated Macrophages and Are Negatively Regulated by IL-10, Dexamethasone, and Lipopolysaccharide

Janet A. Willment, Hsi-Hsen Lin, Delyth M. Reid, Philip R. Taylor, David L. Williams, Simon Y. C. Wong, Siamon Gordon, and Gordon D. Brown
J Immunol 2003 171: 6297. [Full Text] [PDF]  

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