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On the cover: Confocal image of naive T cells infiltrating ulcerative colitis. Naive T cells were identified by simultaneous immunostaining for CD3 (green) and CD45RA (red) and appear yellow. Ag-experienced T cells are CD3+CD45RA- (green), and CD3 -CD45RA+ cells most likely represent B cells. Blood vessels were identified by staining for von Willebrand-factor (blue). Weninger et al. Naive T cell recruitment to nonlymphoid tissues: a role for endothelium-expressed CC chemokine ligand 21 in autoimmune disease and lymphoid neogenesis. J. Immunol. 170:4638.)
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