IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2003 170: 1129-1130. [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: IFN Consensus Sequence Binding Protein/IFN Regulatory Factor 8 Drives the Development of Type I IFN-Producing Plasmacytoid Dendritic Cells

Hideki Tsujimura, Tomohiko Tamura, and Keiko Ozato*
J Immunol 2003 170: 1131-1135. [Abstract] [Full Text] [PDF]  

Cutting Edge: Profile of Chemokine Receptor Expression on Human Plasma Cells Accounts for Their Efficient Recruitment to Target Tissues

Takashi Nakayama, Kunio Hieshima, Dai Izawa, Youichi Tatsumi, Akihisa Kanamaru, and Osamu Yoshie
J Immunol 2003 170: 1136-1140. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Transgenic Expression of RasGRP1 Induces the Maturation of Double-Negative Thymocytes and Enhances the Production of CD8 Single-Positive Thymocytes

Anne M. Norment, Lisa Y. Bogatzki, Mark Klinger, Ethan W. Ojala, Michael J. Bevan, and Robert J. Kay
J Immunol 2003 170: 1141-1149. [Abstract] [Full Text] [PDF]  

Deregulated MHC Class II Transactivator Expression Leads to a Strong Th2 Bias in CD4⁺ T Lymphocytes

Luc A. Otten, Fabienne Tacchini-Cottier, Michael Lohoff, Francesco Annunziato, Lorenzo Cosmi, Leonardo Scarpellino, Jacques Louis, Viktor Steimle, Walter Reith, and Hans Acha-Orbea
J Immunol 2003 170: 1150-1157. [Abstract] [Full Text] [PDF]  

Comparative Effects of Human Ig and Ig in Inducing Autoreactive Antibodies Against B Cells in Mice

Jim J. C. Sheu, Tammy Cheng, Huan Y. Chen, Carmay Lim, and Tse-Wen Chang
J Immunol 2003 170: 1158-1166. [Abstract] [Full Text] [PDF]  

Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages

Brice Campo, Annmarie Surprenant, and R. Alan North
J Immunol 2003 170: 1167-1173. [Abstract] [Full Text] [PDF]  

IFN- Released by Mycobacterium tuberculosis-Infected Human Dendritic Cells Induces the Expression of CXCL10: Selective Recruitment of NK and Activated T Cells

Roberto Lande, Elena Giacomini, Tiziana Grassi, Maria Elena Remoli, Elisabetta Iona, Minja Miettinen, Ilkka Julkunen, and Eliana M. Coccia
J Immunol 2003 170: 1174-1182. [Abstract] [Full Text] [PDF]  

Tumor Eradication by Hepatitis B Virus X Antigen-Specific CD8⁺ T Cells in Xenografted Nude Mice

Eunyoung Chun, Jihyun Lee, Hong Seok Cheong, and Ki-Young Lee
J Immunol 2003 170: 1183-1190. [Abstract] [Full Text] [PDF]  

Cross-Presentation of HLA Class I Epitopes from Exogenous NY-ESO-1 Polypeptides by Nonprofessional APCs

Sacha Gnjatic, Djordje Atanackovic, Mitsutoshi Matsuo, Elke Jäger, Sang Yull Lee, Danila Valmori, Yao-Tseng Chen, Gerd Ritter, Alexander Knuth, and Lloyd J. Old
J Immunol 2003 170: 1191-1196. [Abstract] [Full Text] [PDF]  

The Contribution of NKT Cells, NK Cells, and Other -Chain-Dependent Non-T Non-B Cells to IL-12-Mediated Rejection of Tumors

Se-Ho Park, Tim Kyin, Albert Bendelac, and Claude Carnaud
J Immunol 2003 170: 1197-1201. [Abstract] [Full Text] [PDF]  

Broadening of Epitope Recognition During Immune Rejection of ErbB-2-Positive Tumor Prevents Growth of ErbB-2-Negative Tumor

Shari A. Pilon, Carmen Kelly, and Wei-Zen Wei
J Immunol 2003 170: 1202-1208. [Abstract] [Full Text] [PDF]  

Transfer of TCR Genes into Mature T Cells Is Accompanied by the Maintenance of Parental T Cell Avidity

Mark P. Rubinstein, Andre N. Kadima, Mohamed L. Salem, Christophe L. Nguyen, William E. Gillanders, Michael I. Nishimura, and David J. Cole
J Immunol 2003 170: 1209-1217. [Abstract] [Full Text] [PDF]  

Differential Antigen Sensitivity and Costimulatory Requirements in Human Th1 and Th2 Antigen-Specific CD4⁺ Cells with Similar TCR Avidity

Ursula Holzer, William W. Kwok, Gerald T. Nepom, and Jane Hoyt Buckner
J Immunol 2003 170: 1218-1223. [Abstract] [Full Text] [PDF]  

TCR Reserve: A Novel Principle of CD4 T Cell Activation by Weak Ligands

Lisa K. McNeil and Brian D. Evavold
J Immunol 2003 170: 1224-1230. [Abstract] [Full Text] [PDF]  

Preferential Escape of Subdominant CD8⁺ T Cells During Negative Selection Results in an Altered Antiviral T Cell Hierarchy

Mark K. Slifka, Joseph N. Blattman, David J. D. Sourdive, Fei Liu, Donald L. Huffman, Tom Wolfe, Anna Hughes, Michael B. A. Oldstone, Rafi Ahmed, and Matthias G. von Herrath
J Immunol 2003 170: 1231-1239. [Abstract] [Full Text] [PDF]  

Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo

Anette Sundstedt, Emma J. O’Neill, Kirsty S. Nicolson, and David C. Wraith
J Immunol 2003 170: 1240-1248. [Abstract] [Full Text] [PDF]  

Critical Role of MHC Class I-Related Chain A and B Expression on IFN--Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection

Masahisa Jinushi, Tetsuo Takehara, Tatsuya Kanto, Tomohide Tatsumi, Veronika Groh, Thomas Spies, Takuya Miyagi, Takahiro Suzuki, Yutaka Sasaki, and Norio Hayashi
J Immunol 2003 170: 1249-1256. [Abstract] [Full Text] [PDF]  

Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

Julia A. Brown, David M. Dorfman, Feng-Rong Ma, Elizabeth L. Sullivan, Oliver Munoz, Clive R. Wood, Edward A. Greenfield, and Gordon J. Freeman
J Immunol 2003 170: 1257-1266. [Abstract] [Full Text] [PDF]  

Enhanced Differentiation of Splenic Plasma Cells but Diminished Long-Lived High-Affinity Bone Marrow Plasma Cells in Aged Mice

Shuhua Han, Kaiyong Yang, Zeynep Ozen, Weiyi Peng, Ekaterina Marinova, Garnett Kelsoe, and Biao Zheng
J Immunol 2003 170: 1267-1273. [Abstract] [Full Text] [PDF]  

In Vivo Blockade of Macrophage Migration Inhibitory Factor Ameliorates Acute Experimental Autoimmune Encephalomyelitis by Impairing the Homing of Encephalitogenic T Cells to the Central Nervous System

Claudia M. Denkinger, Michael Denkinger, Jens J. Kort, Christine Metz, and Thomas G. Forsthuber
J Immunol 2003 170: 1274-1282. [Abstract] [Full Text] [PDF]  

Ly6C Induces Clustering of LFA-1 (CD11a/CD18) and Is Involved in Subtype-Specific Adhesion of CD8 T Cells

Ilkka Jaakkola, Marika Merinen, Sirpa Jalkanen, and Arno Hänninen
J Immunol 2003 170: 1283-1290. [Abstract] [Full Text] [PDF]  

Induction of Antigen-Specific CTL by Recombinant HIV Trans-Activating Fusion Protein-Pulsed Human Monocyte-Derived Dendritic Cells

Yoshiyuki Tanaka, Steven F. Dowdy, David C. Linehan, Timothy J. Eberlein, and Peter S. Goedegebuure
J Immunol 2003 170: 1291-1298. [Abstract] [Full Text] [PDF]  

Entry into the Thymic Microenvironment Triggers Notch Activation in the Earliest Migrant T Cell Progenitors

Benjamin C. Harman, Eric J. Jenkinson, and Graham Anderson
J Immunol 2003 170: 1299-1303. [Abstract] [Full Text] [PDF]  

Inhibitory Feedback Loop Between Tolerogenic Dendritic Cells and Regulatory T Cells in Transplant Tolerance

Wei-Ping Min, Dejun Zhou, Thomas E. Ichim, Gill H. Strejan, Xiaoping Xia, Jinming Yang, Xuyan Huang, Bertha Garcia, David White, Patrick Dutartre, Anthony M. Jevnikar, and Robert Zhong
J Immunol 2003 170: 1304-1312. [Abstract] [Full Text] [PDF]  

TGF- Regulates Airway Responses Via T Cells

Christoph Schramm, Udo Herz, Jürgen Podlech, Martina Protschka, Susetta Finotto, Matthias J. Reddehase, Heinz Köhler, Peter R. Galle, Ansgar W. Lohse, and Manfred Blessing
J Immunol 2003 170: 1313-1319. [Abstract] [Full Text] [PDF]  

TNF- Plus IFN- Induce Connexin43 Expression and Formation of Gap Junctions Between Human Monocytes/Macrophages That Enhance Physiological Responses

Eliseo A. Eugenín, María C. Brañes, Joan W. Berman, and Juan C. Sáez
J Immunol 2003 170: 1320-1328. [Abstract] [Full Text] [PDF]  

MHC Class II-Peptide Complexes and APC Lipid Rafts Accumulate at the Immunological Synapse

Elizabeth M. Hiltbold, Neil J. Poloso, and Paul A. Roche
J Immunol 2003 170: 1329-1338. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Rules for Gene Usage Inferred from a Comparison of Large-Scale Gene Expression Profiles of T and B Lymphocyte Development

Reinhard Hoffmann, Ludovica Bruno, Thomas Seidl, Antonius Rolink, and Fritz Melchers
J Immunol 2003 170: 1339-1353. [Abstract] [Full Text] [PDF] Data Supplement  

Block in Development at the Pre-B-II to Immature B Cell Stage in Mice Without Ig and Ig Light Chain

Xiangang Zou, Tony A. Piper, Jennifer A. Smith, Nicholas D. Allen, Jian Xian, and Marianne Brüggemann
J Immunol 2003 170: 1354-1361. [Abstract] [Full Text] [PDF]  

Mimicry of Native Peptide Antigens by the Corresponding Retro-Inverso Analogs Is Dependent on Their Intrinsic Structure and Interaction Propensities

Deepak T. Nair, Kanwal J. Kaur, Kavita Singh, Paushali Mukherjee, Deepa Rajagopal, Anna George, Vineeta Bal, Satyajit Rath, Kanury V. S. Rao, and Dinakar M. Salunke
J Immunol 2003 170: 1362-1373. [Abstract] [Full Text] [PDF]  

Natural Substrates and Inhibitors of Mannan-Binding Lectin-Associated Serine Protease-1 and -2: A Study on Recombinant Catalytic Fragments

Géza Ambrus, Péter Gál, Mayumi Kojima, Katalin Szilágyi, Júlia Balczer, József Antal, László Gráf, Andreas Laich, Beryl E. Moffatt, Wilhelm Schwaeble, Robert B. Sim, and Péter Závodszky
J Immunol 2003 170: 1374-1382. [Abstract] [Full Text] [PDF]  

Suppressor of Cytokine Signaling 1 Inhibits IL-10-Mediated Immune Responses

Yaozhong Ding, Dongmei Chen, Adel Tarcsafalvi, Ruthie Su, Lihui Qin, and Jonathan S. Bromberg
J Immunol 2003 170: 1383-1391. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

The Shift of Th1 to Th2 Immunodominance Associated with the Chronicity of Mycobacterium bovis Bacille Calmette-Guérin Infection Does Not Affect the Memory Response

Xinan Jiao, Richard Lo-Man, Nathalie Winter, Edith Dériaud, Brigitte Gicquel, and Claude Leclerc
J Immunol 2003 170: 1392-1398. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide (LPS)-Binding Protein Mediates LPS Detoxification by Chylomicrons

Anita C. E. Vreugdenhil, Corine H. Rousseau, Thomas Hartung, Jan Willem M. Greve, Cornelis van ‘t Veer, and Wim A. Buurman
J Immunol 2003 170: 1399-1405. [Abstract] [Full Text] [PDF]  

Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut

Gil Melmed, Lisa S. Thomas, Nahee Lee, Samuel Y. Tesfay, Katie Lukasek, Kathrin S. Michelsen, Yuehua Zhou, Bing Hu, Moshe Arditi, and Maria T. Abreu
J Immunol 2003 170: 1406-1415. [Abstract] [Full Text] [PDF]  

A Simian Replication-Defective Adenoviral Recombinant Vaccine to HIV-1 Gag

Julie C. Fitzgerald, Guang-Ping Gao, Arturo Reyes-Sandoval, George N. Pavlakis, Zhi Q. Xiang, Anthony P. Wlazlo, Wynetta Giles-Davis, James M. Wilson, and Hildegund C. J. Ertl
J Immunol 2003 170: 1416-1422. [Abstract] [Full Text] [PDF]  

Nonspecific Recruitment of Memory CD8⁺ T Cells to the Lung Airways During Respiratory Virus Infections

Kenneth H. Ely, Linda S. Cauley, Alan D. Roberts, Jean W. Brennan, Tres Cookenham, and David L. Woodland
J Immunol 2003 170: 1423-1429. [Abstract] [Full Text] [PDF]  

Impaired Clearance of Herpes Simplex Virus Type 1 From Mice Lacking CD1d or NKT Cells Expressing the Semivariant V14-J281 TCR

Branka Grubor-Bauk, Anthony Simmons, Graham Mayrhofer, and Peter G. Speck
J Immunol 2003 170: 1430-1434. [Abstract] [Full Text] [PDF]  

A Soluble Chemokine-Binding Protein from Vaccinia Virus Reduces Virus Virulence and the Inflammatory Response to Infection

Patrick C. Reading, Julian A. Symons, and Geoffrey L. Smith
J Immunol 2003 170: 1435-1442. [Abstract] [Full Text] [PDF]  

A Specific Role for B Cells in the Generation of CD8 T Cell Memory by Recombinant Listeria monocytogenes

Hao Shen, Jason K. Whitmire, Xin Fan, Devon J. Shedlock, Susan M. Kaech, and Rafi Ahmed
J Immunol 2003 170: 1443-1451. [Abstract] [Full Text] [PDF]  

CCL28 Has Dual Roles in Mucosal Immunity as a Chemokine with Broad-Spectrum Antimicrobial Activity

Kunio Hieshima, Haruo Ohtani, Michiko Shibano, Dai Izawa, Takashi Nakayama, Yuri Kawasaki, Fumio Shiba, Mitsuru Shiota, Fuminori Katou, Takuya Saito, and Osamu Yoshie
J Immunol 2003 170: 1452-1461. [Abstract] [Full Text] [PDF]  

Differential Expression of the Murine Mannose-Binding Lectins A and C in Lymphoid and Nonlymphoid Organs and Tissues

Swen Wagner, Nicholas J. Lynch, Wolfgang Walter, Wilhelm J. Schwaeble, and Michael Loos
J Immunol 2003 170: 1462-1465. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

The Long Pentraxin Ptx3 Is Synthesized in IgA Glomerulonephritis and Activates Mesangial Cells

Benedetta Bussolati, Giuseppe Peri, Gennaro Salvidio, Daniela Verzola, Alberto Mantovani, and Giovanni Camussi
J Immunol 2003 170: 1466-1472. [Abstract] [Full Text] [PDF]  

MHC Class II-Associated Invariant Chain Isoforms Regulate Pulmonary Immune Responses

Qiang Ye, Patricia W. Finn, Ruth Sweeney, Elizabeth K. Bikoff, and Richard J. Riese
J Immunol 2003 170: 1473-1480. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Cytochrome P4502D6_193–212: A New Immunodominant Epitope and Target of Virus/Self Cross-Reactivity in Liver Kidney Microsomal Autoantibody Type 1-Positive Liver Disease

Nanda Kerkar, Kaushik Choudhuri, Yun Ma, Ayman Mahmoud, Dimitrios P. Bogdanos, Luigi Muratori, Francesco Bianchi, Roger Williams, Giorgina Mieli-Vergani, and Diego Vergani
J Immunol 2003 170: 1481-1489. [Abstract] [Full Text] [PDF]  

CD4⁺ Th2 Cell Recognition of HLA-DR-Restricted Epitopes Derived from CAMEL: A Tumor Antigen Translated in an Alternative Open Reading Frame

Elisabeth H. Slager, Martina Borghi, Carolien E. van der Minne, Corlien A. Aarnoudse, Menzo J. E. Havenga, Peter I. Schrier, Susanne Osanto, and Marieke Griffioen
J Immunol 2003 170: 1490-1497. [Abstract] [Full Text] [PDF]  

Induction of Antigen-Specific CTL Responses Using Antigens Conjugated to Short Peptide Vectors

Fiona H. Day, Yu Zhang, Philippe Clair, Kenneth H. Grabstein, Martine Mazel, Anthony R. Rees, Michel Kaczorek, and Jamal Temsamani
J Immunol 2003 170: 1498-1503. [Abstract] [Full Text] [PDF]  

Bordetella pertussis Infection in 2-Month-Old Infants Promotes Type 1 T Cell Responses

Françoise Mascart, Virginie Verscheure, Anne Malfroot, Marc Hainaut, Denis Piérard, Stéphane Temerman, Alexandra Peltier, Anne-Sophie Debrie, Jack Levy, Giuseppe Del Giudice, and Camille Locht
J Immunol 2003 170: 1504-1509. [Abstract] [Full Text] [PDF]  

CD28/B7 Regulation of Anti-CD3-Mediated Immunosuppression In Vivo

Qizhi Tang, Judy A. Smith, Greg L. Szot, Ping Zhou, Maria-Luisa Alegre, Kammi J. Henriksen, Craig B. Thompson, and Jeffrey A. Bluestone
J Immunol 2003 170: 1510-1516. [Abstract] [Full Text] [PDF]  

Lack of a Functional Alternative Complement Pathway Ameliorates Ischemic Acute Renal Failure in Mice

Joshua M. Thurman, Danica Ljubanovic, Charles L. Edelstein, Gary S. Gilkeson, and V. Michael Holers
J Immunol 2003 170: 1517-1523. [Abstract] [Full Text] [PDF]  

A Novel Anti-Inflammatory Role for Simvastatin in Inflammatory Arthritis

Bernard P. Leung, Naveed Sattar, Anne Crilly, Morag Prach, David W. McCarey, Helen Payne, Rajan Madhok, Carol Campbell, J. Alastair Gracie, Foo Y. Liew, and Iain B. McInnes
J Immunol 2003 170: 1524-1530. [Abstract] [Full Text] [PDF]  

The In Vitro and In Vivo Effects of Anti-Galactose Antibodies on Endothelial Cell Activation and Xenograft Rejection

Hui Xu, Dengping Yin, Bashoo Naziruddin, Libing Chen, Aileen Stark, Yuanyuan Wei, Ying Lei, JiKun Shen, John S. Logan, Guerard W. Byrne, and Anita S.-F. Chong
J Immunol 2003 170: 1531-1539. [Abstract] [Full Text] [PDF]  

Increased Bone Mass Is a Part of the Generalized Lymphoproliferative Disorder Phenotype in the Mouse

Vedran Katavic, Ivan Kresimir Lukic, Natasa Kovacic, Danka Grcevic, Joseph A. Lorenzo, and Ana Marusic
J Immunol 2003 170: 1540-1547. [Abstract] [Full Text] [PDF]  

Oral Feeding with Ethinyl Estradiol Suppresses and Treats Experimental Autoimmune Encephalomyelitis in SJL Mice and Inhibits the Recruitment of Inflammatory Cells into the Central Nervous System

Sandhya Subramanian, Agata Matejuk, Alex Zamora, Arthur A. Vandenbark, and Halina Offner
J Immunol 2003 170: 1548-1555. [Abstract] [Full Text] [PDF]  

Peptide Nucleic Acid Antisense Prolongs Skin Allograft Survival by Means of Blockade of CXCR3 Expression Directing T Cells into Graft

Ming Jiankuo, Wang Xingbing, Huang Baojun, Wu Xiongwin, Li Zhuoya, Xiong Ping, Xu Yong, Liu Anting, Hu Chunsong, Gong Feili, and Tan Jinquan
J Immunol 2003 170: 1556-1565. [Abstract] [Full Text] [PDF]  

Induction of Apoptosis by HIV-1-Infected Monocytic Cells

Kirk Sperber, Prarthana Beuria, Netai Singha, Irwin Gelman, Patricia Cortes, Houchu Chen, and Thomas Kraus
J Immunol 2003 170: 1566-1578. [Abstract] [Full Text] [PDF]  

Normal Tissue Depresses While Tumor Tissue Enhances Human T Cell Responses In Vivo to a Novel Self/Tumor Melanoma Antigen, OA1

Christopher E. Touloukian, Wolfgang W. Leitner, Rhonda E. Schnur, Paul F. Robbins, Yong Li, Scott Southwood, Alessandro Sette, Steven A. Rosenberg, and Nicholas P. Restifo
J Immunol 2003 170: 1579-1585. [Abstract] [Full Text] [PDF]  

Transcutaneous Immunization with Cholera Toxin B Subunit Adjuvant Suppresses IgE Antibody Responses Via Selective Induction of Th1 Immune Responses

Fabienne Anjuère, Annie George-Chandy, Florence Audant, Déborah Rousseau, Jan Holmgren, and Cecil Czerkinsky
J Immunol 2003 170: 1586-1592. [Abstract] [Full Text] [PDF]  

LETTER OF RETRACTION:

SF20/IL-25, a Novel Bone Marrow Stroma-Derived Growth Factor That Binds to Mouse Thymic Shared Antigen-1 and Supports Lymphoid Cell Proliferation

Edgardo E. Tulin, Nobuhisa Onoda, Yasuhiko Nakata, Masatsugu Maeda, Masakazu Hasegawa, Hitoshi Nomura, and Toshio Kitamura
J Immunol 2003 170: 1593. [Full Text] [PDF]  

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