IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2003 170: 5343-5344. [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Major CD8 T Cell Response to Live Bacillus Calmette-Guérin Is Mediated by CD1 Molecules

Tetsuo Kawashima, Yoshihiko Norose, Yoshiyuki Watanabe, Yutaka Enomoto, Hidehiko Narazaki, Eiji Watari, Shigeo Tanaka, Hidemi Takahashi, Ikuya Yano, Michael B. Brenner, and Masahiko Sugita
J Immunol 2003 170: 5345-5348. [Abstract] [Full Text] [PDF]  

Cutting Edge: Bradykinin Induces IL-12 Production by Dendritic Cells: A Danger Signal That Drives Th1 Polarization

Julio Aliberti, João P. B. Viola, Adriana Vieira-de-Abreu, Patricia T. Bozza, Alan Sher, and Julio Scharfstein
J Immunol 2003 170: 5349-5353. [Abstract] [Full Text] [PDF]  

Cutting Edge: Monarch-1: A Pyrin/Nucleotide-Binding Domain/Leucine-Rich Repeat Protein That Controls Classical and Nonclassical MHC Class I Genes

Kristi L. Williams, Debra J. Taxman, Michael W. Linhoff, William Reed, and Jenny P.-Y. Ting
J Immunol 2003 170: 5354-5358. [Abstract] [Full Text] [PDF] Data Supplement  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Differential Regulation of Human Eosinophil IL-3, IL-5, and GM-CSF Receptor -Chain Expression by Cytokines: IL-3, IL-5, and GM-CSF Down-Regulate IL-5 Receptor Expression with Loss of IL-5 Responsiveness, but Up-Regulate IL-3 Receptor Expression

Bernard Gregory, Antje Kirchem, Simon Phipps, Phillipe Gevaert, Carol Pridgeon, Sara M. Rankin, and Douglas S. Robinson
J Immunol 2003 170: 5359-5366. [Abstract] [Full Text] [PDF]  

Dendritic Cells Process and Present Antigens Across A Range of Maturation States

Ravi K. Veeraswamy, Marina Cella, Marco Colonna, and Emil R. Unanue
J Immunol 2003 170: 5367-5372. [Abstract] [Full Text] [PDF]  

Stimulation of Primary Human Endothelial Cell Proliferation by IFN

Dolores Gomez and Nancy C. Reich
J Immunol 2003 170: 5373-5381. [Abstract] [Full Text] [PDF]  

Differential Regulation of Vitamin D Receptor and Its Ligand in Human Monocyte-Derived Dendritic Cells

Martin Hewison, Lisa Freeman, Susan V. Hughes, Katie N. Evans, Rosemary Bland, Aristides G. Eliopoulos, Mark D. Kilby, Paul A. H. Moss, and Ronjon Chakraverty
J Immunol 2003 170: 5382-5390. [Abstract] [Full Text] [PDF]  

Generation of Cytotoxic Responses in Mice and Human Individuals Against Hematological Malignancies Using Survivin-RNA-Transfected Dendritic Cells

Matthias Zeis, Sandra Siegel, Andreas Wagner, Marc Schmitz, Matthias Marget, Rita Kühl-Burmeister, Ilse Adamzik, Dieter Kabelitz, Peter Dreger, Norbert Schmitz, and Axel Heiser
J Immunol 2003 170: 5391-5397. [Abstract] [Full Text] [PDF]  

NK Cell Tolerance in Mixed Allogeneic Chimeras

Yong Zhao, Hideki Ohdan, Jennifer O. Manilay, and Megan Sykes
J Immunol 2003 170: 5398-5405. [Abstract] [Full Text] [PDF]  

Mature But Not Immature Fas Ligand (CD95L)-Transduced Human Monocyte-Derived Dendritic Cells Are Protected from Fas-Mediated Apoptosis and Can Be Used as Killer APC

Sabine Hoves, Stefan W. Krause, Dagmar Halbritter, Huang-Ge Zhang, John D. Mountz, Jürgen Schölmerich, and Martin Fleck
J Immunol 2003 170: 5406-5413. [Abstract] [Full Text] [PDF]  

Memory Phenotype of CD8⁺ T Cells in MHC Class Ia-Deficient Mice

Zoran Kurepa, Jie Su, and James Forman
J Immunol 2003 170: 5414-5420. [Abstract] [Full Text] [PDF]  

A Role for the B7-1/B7-2:CD28/CTLA-4 Pathway During Negative Selection

Janet E. Buhlmann, Sheryl Krevsky Elkin, and Arlene H. Sharpe
J Immunol 2003 170: 5421-5428. [Abstract] [Full Text] [PDF]  

Genetic Dissection of V14J18 Natural T Cell Number and Function in Autoimmune-Prone Mice

Naoto Matsuki, Aleksandar K. Stanic, Monica E. Embers, Luc Van Kaer, Laurence Morel, and Sebastian Joyce
J Immunol 2003 170: 5429-5437. [Abstract] [Full Text] [PDF]  

IL-23 Production by Cosecretion of Endogenous p19 and Transgenic p40 in Keratin 14/p40 Transgenic Mice: Evidence for Enhanced Cutaneous Immunity

Tamara Kopp, Petra Lenz, Concha Bello-Fernandez, Robert A. Kastelein, Thomas S. Kupper, and Georg Stingl
J Immunol 2003 170: 5438-5444. [Abstract] [Full Text] [PDF]  

Stimulation of Toll-Like Receptor 4 by Lipopolysaccharide During Cellular Invasion by Live Salmonella typhimurium Is a Critical But Not Exclusive Event Leading to Macrophage Responses

Matthew C. J. Royle, Sabine Tötemeyer, Louise C. Alldridge, Duncan J. Maskell, and Clare E. Bryant
J Immunol 2003 170: 5445-5454. [Abstract] [Full Text] [PDF]  

TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells

Ellen N. Kersh, Susan M. Kaech, Thandi M. Onami, Miriana Moran, E. John Wherry, M. Carrie Miceli, and Rafi Ahmed
J Immunol 2002 170: 5455-5463. [Abstract] [Full Text] [PDF]  

IL-21 in Synergy with IL-15 or IL-18 Enhances IFN- Production in Human NK and T Cells

Mari Strengell, Sampsa Matikainen, Jukka Sirén, Anne Lehtonen, Don Foster, Ilkka Julkunen, and Timo Sareneva
J Immunol 2003 170: 5464-5469. [Abstract] [Full Text] [PDF]  

Propagation and Control of T Cell Responses by Heparan Sulfate-Bound IL-2

Lucile E. Wrenshall, Jeffrey L. Platt, Elliot T. Stevens, Thomas N. Wight, and John D. Miller
J Immunol 2003 170: 5470-5474. [Abstract] [Full Text] [PDF]  

Isolated Lymphoid Follicle Formation Is Inducible and Dependent Upon Lymphotoxin-Sufficient B Lymphocytes, Lymphotoxin Receptor, and TNF Receptor I Function

Robin G. Lorenz, David D. Chaplin, Keely G. McDonald, Jacquelyn S. McDonough, and Rodney D. Newberry
J Immunol 2003 170: 5475-5482. [Abstract] [Full Text] [PDF]  

Drug-Inducible, Dendritic Cell-Based Genetic Immunization

Laura Timares, Karim Mahmoud Safer, Baoxi Qu, Akira Takashima, and Stephen Albert Johnston
J Immunol 2003 170: 5483-5490. [Abstract] [Full Text] [PDF]  

IL-12 Administration Accelerates Autoimmune Diabetes in Both Wild-Type and IFN--Deficient Nonobese Diabetic Mice, Revealing Pathogenic and Protective Effects of IL-12-Induced IFN-

Sylvie Trembleau, Giuseppe Penna, Silvia Gregori, Nadia Giarratana, and Luciano Adorini
J Immunol 2003 170: 5491-5501. [Abstract] [Full Text] [PDF]  

Lung CD25 CD4 Regulatory T Cells Suppress Type 2 Immune Responses But Not Bronchial Hyperreactivity

Husein Hadeiba and Richard M. Locksley
J Immunol 2003 170: 5502-5510. [Abstract] [Full Text] [PDF]  

Selective Induction of Dendritic Cells Using Granulocyte Macrophage-Colony Stimulating Factor, But Not fms-Like Tyrosine Kinase Receptor 3-Ligand, Activates Thyroglobulin-Specific CD4⁺/CD25⁺ T Cells and Suppresses Experimental Autoimmune Thyroiditis

Chenthamarakshan Vasu, Rukiye-Nazan E. Dogan, Mark J. Holterman, and Bellur S. Prabhakar
J Immunol 2003 170: 5511-5522. [Abstract] [Full Text] [PDF]  

Thyroid-Specific Expression of IFN- Limits Experimental Autoimmune Thyroiditis by Suppressing Lymphocyte Activation in Cervical Lymph Nodes

Jobert G. Barin, Marina Afanasyeva, Monica V. Talor, Noel R. Rose, C. Lynne Burek, and Patrizio Caturegli
J Immunol 2003 170: 5523-5529. [Abstract] [Full Text] [PDF]  

Absence of Allograft ICAM-1 Attenuates Alloantigen-Specific T Cell Priming, But Not Primed T Cell Trafficking into the Graft, to Mediate Acute Rejection

Qi-Wei Zhang, Danielle D. Kish, and Robert L. Fairchild
J Immunol 2003 170: 5530-5537. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Notch Signaling Induces Multilineage Myeloid Differentiation and Up-Regulates PU.1 Expression

Timm Schroeder, Hella Kohlhof, Nikolaus Rieber, and Ursula Just
J Immunol 2003 170: 5538-5548. [Abstract] [Full Text] [PDF]  

Yin Yang 1 Is a Lipopolysaccharide-Inducible Activator of the Murine 3' Igh Enhancer, hs3

Steven J. Gordon, Shireen Saleque, and Barbara K. Birshtein
J Immunol 2003 170: 5549-5557. [Abstract] [Full Text] [PDF]  

Normal Somatic Hypermutation of Ig Genes in the Absence of 8-Hydroxyguanine-DNA Glycosylase

David B. Winter, Quy H. Phung, Xianmin Zeng, Erling Seeberg, Deborah E. Barnes, Tomas Lindahl, and Patricia J. Gearhart
J Immunol 2003 170: 5558-5562. [Abstract] [Full Text] [PDF]  

Uncoupling of Promitogenic and Antiapoptotic Functions of IL-2 by Smad-Dependent TGF- Signaling

Brad H. Nelson, Timothy P. Martyak, Lucas J. Thompson, James J. Moon, and Tongwen Wang
J Immunol 2003 170: 5563-5570. [Abstract] [Full Text] [PDF]  

IL-18 Receptor -Induced Changes in the Presentation of IL-18 Binding Sites Affect Ligand Binding and Signal Transduction

Chengbin Wu, Paul Sakorafas, Renee Miller, Donna McCarthy, Susanne Scesney, Richard Dixon, and Tariq Ghayur
J Immunol 2003 170: 5571-5577. [Abstract] [Full Text] [PDF]  

Novel Variants of the IL-10 Receptor 1 Affect Inhibition of Monocyte TNF- Production

Christoph Gasche, Paul Grundtner, Petra Zwirn, Walter Reinisch, Sarah H. Shaw, Alexander Zdanov, Usha Sarma, Lynn M. Williams, Brian M. Foxwell, and Alfred Gangl
J Immunol 2003 170: 5578-5582. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Wound Healing and Expression of Antimicrobial Peptides/Polypeptides in Human Keratinocytes, a Consequence of Common Growth Factors

Ole E. Sørensen, Jack B. Cowland, Kim Theilgaard-Mönch, Lide Liu, Tomas Ganz, and Niels Borregaard
J Immunol 2003 170: 5583-5589. [Abstract] [Full Text] [PDF]  

Mast Cell Activation by Mycobacterium tuberculosis: Mediator Release and Role of CD48

Samira Muñoz, Rogelio Hernández-Pando, Soman N. Abraham, and Jose Antonio Enciso
J Immunol 2003 170: 5590-5596. [Abstract] [Full Text] [PDF]  

Renewal of Peripheral CD8⁺ Memory T Cells During Secondary Viral Infection of Antibody-Sufficient Mice

Linda S. Cauley, Tres Cookenham, Robert J. Hogan, Sherry R. Crowe, and David L. Woodland
J Immunol 2003 170: 5597-5606. [Abstract] [Full Text] [PDF]  

Subversion and Utilization of the Host Cell Cyclic Adenosine 5'-Monophosphate/Protein Kinase A Pathway by Brucella During Macrophage Infection

Antoine Gross, Monsif Bouaboula, Pierre Casellas, Jean-Pierre Liautard, and Jacques Dornand
J Immunol 2003 170: 5607-5614. [Abstract] [Full Text] [PDF]  

Hepatitis C Virus Core and Nonstructural Protein 3 Proteins Induce Pro- and Anti-inflammatory Cytokines and Inhibit Dendritic Cell Differentiation

Angela Dolganiuc, Karen Kodys, Andrea Kopasz, Christopher Marshall, Twan Do, Laszlo Romics, Jr., Pranoti Mandrekar, Maria Zapp, and Gyongyi Szabo
J Immunol 2003 170: 5615-5624. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Based Immunotherapy Combined with Antimony-Based Chemotherapy Cures Established Murine Visceral Leishmaniasis

Monidipa Ghosh, Chiranjib Pal, Mitali Ray, Sudipta Maitra, Labanya Mandal, and Santu Bandyopadhyay
J Immunol 2003 170: 5625-5629. [Abstract] [Full Text] [PDF]  

IKK Plays an Essential Role in the Phosphorylation of RelA/p65 on Serine 536 Induced by Lipopolysaccharide

Fan Yang, Eric Tang, Kunliang Guan, and Cun-Yu Wang
J Immunol 2003 170: 5630-5635. [Abstract] [Full Text] [PDF]  

Effective Mucosal Immunity to Anthrax: Neutralizing Antibodies and Th Cell Responses Following Nasal Immunization with Protective Antigen

Prosper N. Boyaka, Angela Tafaro, Romy Fischer, Stephen H. Leppla, Kohtaro Fujihashi, and Jerry R. McGhee
J Immunol 2003 170: 5636-5643. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Urokinase-Type Plasminogen Activator Potentiates Lipopolysaccharide-Induced Neutrophil Activation

Edward Abraham, Margaret R. Gyetko, Katherine Kuhn, John Arcaroli, Derek Strassheim, Jong Sung Park, Sreerama Shetty, and Steven Idell
J Immunol 2003 170: 5644-5651. [Abstract] [Full Text] [PDF]  

Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions

Michael Glogauer, Christophe C. Marchal, Fei Zhu, Aelaf Worku, Björn E. Clausen, Irmgard Foerster, Peter Marks, Gregory P. Downey, Mary Dinauer, and David J. Kwiatkowski
J Immunol 2003 170: 5652-5657. [Abstract] [Full Text] [PDF]  

CC Chemokine Ligand 5/RANTES Chemokine Antagonists Aggravate Glomerulonephritis Despite Reduction of Glomerular Leukocyte Infiltration

Hans-Joachim Anders, Michael Frink, Yvonne Linde, Bernard Banas, Markus Wörnle, Clemens D. Cohen, Volker Vielhauer, Peter J. Nelson, Hermann-Josef Gröne, and Detlef Schlöndorff
J Immunol 2003 170: 5658-5666. [Abstract] [Full Text] [PDF]  

Tryptase Precursors Are Preferentially and Spontaneously Released, Whereas Mature Tryptase Is Retained by HMC-1 Cells, Mono-Mac-6 Cells, and Human Skin-Derived Mast Cells

Lawrence B. Schwartz, Hae-Ki Min, Shunlin Ren, Han-Zhang Xia, Jiang Hu, Wei Zhao, George Moxley, and Yoshihiro Fukuoka
J Immunol 2003 170: 5667-5673. [Abstract] [Full Text] [PDF]  

IFN Regulatory Factor-1 Is Required for the Up-Regulation of the CD40-NF-B Activator 1 Axis During Airway Inflammation

Zhendong Zhao, Youcun Qian, Dave Wald, Yi-Feng Xia, Jian-Guo Geng, and Xiaoxia Li
J Immunol 2003 170: 5674-5680. [Abstract] [Full Text] [PDF]  

Regulation of Airway Epithelial Cell NF-B-Dependent Gene Expression by Protein Kinase C

Kristen Page, Jing Li, Limei Zhou, Svetlana Iasvoyskaia, Kevin C. Corbit, Jae-Won Soh, I. Bernard Weinstein, Allan R. Brasier, Anning Lin, and Marc B. Hershenson
J Immunol 2003 170: 5681-5689. [Abstract] [Full Text] [PDF]  

Neutrophil Serine Proteinases Activate Human Nonepithelial Cells to Produce Inflammatory Cytokines Through Protease-Activated Receptor 2

Akiko Uehara, Koji Muramoto, Haruhiko Takada, and Shunji Sugawara
J Immunol 2003 170: 5690-5696. [Abstract] [Full Text] [PDF]  

IL-1, Innate Immunity, and Skin Carcinogenesis: The Effect of Constitutive Expression of IL-1 in Epidermis on Chemical Carcinogenesis

Jo-Ellen Murphy, Romeo E. Morales, Jordan Scott, and Thomas S. Kupper
J Immunol 2003 170: 5697-5703. [Abstract] [Full Text] [PDF]  

Synergistic Effect of TNF- in Soluble VCAM-1-Induced Angiogenesis Through ₄ Integrins

Shintaro Nakao, Takashi Kuwano, Tatsuro Ishibashi, Michihiko Kuwano, and Mayumi Ono
J Immunol 2003 170: 5704-5711. [Abstract] [Full Text] [PDF]  

T Cells of Atopic Asthmatics Preferentially Infiltrate Into Human Bronchial Xenografts in SCID Mice

Kaori Tsumori, Hirotsugu Kohrogi, Eisuke Goto, Naomi Hirata, Susumu Hirosako, Kazuhiko Fujii, Makoto Ando, Osamu Kawano, and Hiroshi Mizuta
J Immunol 2003 170: 5712-5718. [Abstract] [Full Text] [PDF]  

Localization of MHC Class II/Human Cartilage Glycoprotein-39 Complexes in Synovia of Rheumatoid Arthritis Patients Using Complex-Specific Monoclonal Antibodies

Peter G. A. Steenbakkers, Dominique Baeten, Eric Rovers, Eric M. Veys, Antonius W. M. Rijnders, Jan Meijerink, Filip De Keyser, and Annemieke M. H. Boots
J Immunol 2003 170: 5719-5727. [Abstract] [Full Text] [PDF]  

P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1 Release

Philip A. Verhoef, Mark Estacion, William Schilling, and George R. Dubyak
J Immunol 2003 170: 5728-5738. [Abstract] [Full Text] [PDF] Data Supplement  

Regulation of Lipopolysaccharide Sensitivity by IFN Regulatory Factor-2

Natalia Cuesta, Cindy A. Salkowski, Karen E. Thomas, and Stefanie N. Vogel
J Immunol 2003 170: 5739-5747. [Abstract] [Full Text] [PDF]  

Expression of a Novel Murine Type I IFN in the Pancreatic Islets Induces Diabetes in Mice

Galya Vassileva, Shu-Cheng Chen, Ming Zeng, Susan Abbondanzo, Kristian Jensen, Daniel Gorman, Bahige M. Baroudy, Ying Jiang, Nicholas Murgolo, and Sergio A. Lira
J Immunol 2003 170: 5748-5755. [Abstract] [Full Text] [PDF]  

Marked Airway Eosinophilia Prevents Development of Airway Hyper-responsiveness During an Allergic Response in IL-5 Transgenic Mice

Takao Kobayashi, Koji Iijima, and Hirohito Kita
J Immunol 2003 170: 5756-5763. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Complement C5a Receptor-Mediated Signaling May Be Involved in Neurodegeneration in Alzheimer’s Disease

Imre Farkas, Mitsuo Takahashi, Atsuo Fukuda, Naoki Yamamoto, Hiroyasu Akatsu, Lajos Baranyi, Hisashi Tateyama, Takayuki Yamamoto, Noriko Okada, and Hidechika Okada
J Immunol 2003 170: 5764-5771. [Abstract] [Full Text] [PDF]  

Impaired Secretion of IL-10 by T Cells from Patients with Common Variable Immunodeficiency–Involvement of Protein Kinase A Type I

Are Martin Holm, Pål Aukrust, Einar Martin Aandahl, Fredrik Müller, Kjetil Taskén, and Stig S. Frøland
J Immunol 2003 170: 5772-5777. [Abstract] [Full Text] [PDF]  

Allospecific T Cell Epitope Sharing Reveals Extensive Conservation of the Antigenic Features of Peptide Ligands Among HLA-B27 Subtypes Differentially Associated with Spondyloarthritis

Veronica Montserrat, Mercè Martí, and José A. López de Castro
J Immunol 2003 170: 5778-5785. [Abstract] [Full Text] [PDF]  

HIV-1 Replication Increases HIV-Specific CD4⁺ T Cell Frequencies but Limits Proliferative Capacity in Chronically Infected Children

Zachary A. Scott, Coreen M. Beaumier, Mark Sharkey, Mario Stevenson, and Katherine Luzuriaga
J Immunol 2003 170: 5786-5792. [Abstract] [Full Text] [PDF]  

Retinoic Acid Reduces Autoimmune Renal Injury and Increases Survival in NZB/W F₁ Mice

Koji Kinoshita, Byun-Suk Yoo, Yuji Nozaki, Masafumi Sugiyama, Shinya Ikoma, Motoki Ohno, Masanori Funauchi, and Akihisa Kanamaru
J Immunol 2003 170: 5793-5798. [Abstract] [Full Text] [PDF]  

CORRECTION:

J Immunol 2003 170: 5799. [Full Text] [PDF]  

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