CUTTING EDGE:

Cutting Edge: Differential Signaling Requirements for Activation of Assembled Cyclin D3-cdk4 Complexes in B-1 and B-2 Lymphocyte Subsets

Debra A. Tanguay, Thomas P. Colarusso, Cheryl Doughty, Sandra Pavlovic-Ewers, Thomas L. Rothstein, and Thomas C. Chiles
J Immunol 2001 166: 4273-4277. [Abstract] [Full Text] [PDF]  

Cutting Edge: In Vivo Identification of TCR Redistribution and Polarized IL-2 Production by Naive CD4 T Cells

Peter Reichert, R. Lee Reinhardt, Elizabeth Ingulli, and Marc K. Jenkins
J Immunol 2001 166: 4278-4281. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Antigen-Independent Th2 Cell Differentiation by Stimulation of CD28: Regulation Via IL-4 Gene Expression and Mitogen-Activated Protein Kinase Activation

Alla Skapenko, Peter E. Lipsky, Hans-Georg Kraetsch, Joachim R. Kalden, and Hendrik Schulze-Koops
J Immunol 2001 166: 4283-4292. [Abstract] [Full Text] [PDF]  

Stromal Cell-Derived Factor-1-Induced LFA-1 Activation During In Vivo Migration of T Cell Hybridoma Cells Requires G_q/11, RhoA, and Myosin, as well as G_i and Cdc42

Ron D. M. Soede, Ingrid S. Zeelenberg, Yvonne M. Wijnands, Marga Kamp, and Ed Roos
J Immunol 2001 166: 4293-4301. [Abstract] [Full Text] [PDF]  

Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells

Katrien Van Beneden, Frederik Stevenaert, An De Creus, Veronique Debacker, Jozef De Boever, Jean Plum, and Georges Leclercq
J Immunol 2001 166: 4302-4311. [Abstract] [Full Text] [PDF]  

Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions

Silvia Corinti, Cristina Albanesi, Andrea la Sala, Saveria Pastore, and Giampiero Girolomoni
J Immunol 2001 166: 4312-4318. [Abstract] [Full Text] [PDF]  

Identification of an IL-2 Binding Protein in the Saliva of the Lyme Disease Vector Tick, Ixodes scapularis

R. Dean Gillespie, Marc C. Dolan, Joseph Piesman, and Richard G. Titus
J Immunol 2001 166: 4319-4326. [Abstract] [Full Text] [PDF]  

T Cells Are Needed for Ocular Immune Privilege and Corneal Graft Survival

Molly E. Skelsey, Jessamee Mellon, and Jerry Y. Niederkorn
J Immunol 2001 166: 4327-4333. [Abstract] [Full Text] [PDF]  

In Vivo Neutralization of Human IL-6 (hIL-6) Achieved by Immunization of hIL-6-Transgenic Mice with a hIL-6 Receptor Antagonist

Fabrizio De Benedetti, Patrizia Pignatti, Marina Vivarelli, Cristina Meazza, Gennaro Ciliberto, Rocco Savino, and Alberto Martini
J Immunol 2001 166: 4334-4340. [Abstract] [Full Text] [PDF]  

Biological Activity of Soluble CD100. I. The Extracellular Region of CD100 Is Released from the Surface of T Lymphocytes by Regulated Proteolysis

Abdellah Elhabazi, Stéphanie Delaire, Armand Bensussan, Laurence Boumsell, and Georges Bismuth
J Immunol 2001 166: 4341-4347. [Abstract] [Full Text] [PDF]  

Biological Activity of Soluble CD100. II. Soluble CD100, Similarly to H-SemaIII, Inhibits Immune Cell Migration

Stéphanie Delaire, Christian Billard, Rafaèle Tordjman, Alain Chédotal, Abdellah Elhabazi, Armand Bensussan, and Laurence Boumsell
J Immunol 2001 166: 4348-4354. [Abstract] [Full Text] [PDF]  

Multiple Antigen-Specific Processing Pathways for Activating Naive CD8⁺ T Cells In Vivo

Christopher C. Norbury, Michael F. Princiotta, Igor Bacik, Randy R. Brutkiewicz, Philip Wood, Tim Elliott, Jack R. Bennink, and Jonathan W. Yewdell
J Immunol 2001 166: 4355-4362. [Abstract] [Full Text] [PDF]  

Endogenous Oocyte Antigens Are Required for Rapid Induction and Progression of Autoimmune Ovarian Disease Following Day-3 Thymectomy

Pascale Alard, Claire Thompson, Sally S. Agersborg, Jayant Thatte, Yulius Setiady, Eileen Samy, and Kenneth S. K. Tung
J Immunol 2001 166: 4363-4369. [Abstract] [Full Text] [PDF]  

Quantitative Analysis of the Immune Response to Mouse Non-MHC Transplantation Antigens In Vivo: The H60 Histocompatibility Antigen Dominates Over All Others

Eun Young Choi, Yoshitaka Yoshimura, Gregory J. Christianson, Thomas J. Sproule, Subramaniam Malarkannan, Nilabh Shastri, Sebastian Joyce, and Derry C. Roopenian
J Immunol 2001 166: 4370-4379. [Abstract] [Full Text] [PDF]  

Diversity of the Killer Cell Ig-Like Receptors of Rhesus Monkeys

Karen L. Hershberger, Richa Shyam, Ayako Miura, and Norman L. Letvin
J Immunol 2001 166: 4380-4390. [Abstract] [Full Text] [PDF]  

IL-9 and IL-13 Production by Activated Mast Cells Is Strongly Enhanced in the Presence of Lipopolysaccharide: NF-B Is Decisively Involved in the Expression of IL-9

Michael Stassen, Christian Müller, Martina Arnold, Lothar Hültner, Stefan Klein-Hessling, Christine Neudörfl, Tanja Reineke, Edgar Serfling, and Edgar Schmitt
J Immunol 2001 166: 4391-4398. [Abstract] [Full Text] [PDF]  

Regulation of Activator Protein-1 and NF-B in CD8⁺ T Cells Exposed To Peripheral Self-Antigens

Sylvie Guerder, Mercedes Rincòn, and Anne-Marie Schmitt-Verhulst
J Immunol 2001 166: 4399-4407. [Abstract] [Full Text] [PDF]  

p62^dok Negatively Regulates CD2 Signaling in Jurkat Cells

Jean-Guy Némorin, Pierre Laporte, Geneviève Bérubé, and Pascale Duplay
J Immunol 2001 166: 4408-4415. [Abstract] [Full Text] [PDF]  

Nuclear Shuttling of Mitogen-Activated Protein (MAP) Kinase (Extracellular Signal-Regulated Kinase (ERK) 2) Was Dynamically Controlled by MAP/ERK Kinase After Antigen Stimulation in RBL-2H3 Cells

Tadahide Furuno, Naohide Hirashima, Shinobu Onizawa, Noriko Sagiya, and Mamoru Nakanishi
J Immunol 2001 166: 4416-4421. [Abstract] [Full Text] [PDF]  

The NK Cell MHC Class I Receptor Ly49A Detects Mutations on H-2D^d Inside and Outside of the Peptide Binding Groove

Naoki Matsumoto, Wayne M. Yokoyama, Somei Kojima, and Kazuo Yamamoto
J Immunol 2001 166: 4422-4428. [Abstract] [Full Text] [PDF]  

A Role for Accessibility to Self-Peptide-Self-MHC Complexes in Intrathymic Negative Selection

Christophe Viret, Derek B. Sant’Angelo, Xin He, Hemavathi Ramaswamy, and Charles A. Janeway, Jr.
J Immunol 2001 166: 4429-4437. [Abstract] [Full Text] [PDF]  

Distinguishing Self from Nonself: Immunogenicity of the Murine H47 Locus Is Determined by a Single Amino Acid Substitution in an Unusual Peptide

Lisa M. Mendoza, Gilbert Villaflor, Peter Eden, Derry Roopenian, and Nilabh Shastri
J Immunol 2001 166: 4438-4445. [Abstract] [Full Text] [PDF]  

Inducible Expression of Stat4 in Dendritic Cells and Macrophages and Its Critical Role in Innate and Adaptive Immune Responses

Taro Fukao, David M. Frucht, George Yap, Massimo Gadina, John J. O’Shea, and Shigeo Koyasu
J Immunol 2001 166: 4446-4455. [Abstract] [Full Text] [PDF]  

B Cell-Deficient (µMT) Mice Have Alterations in the Cytokine Microenvironment of the Gut-Associated Lymphoid Tissue (GALT) and a Defect in the Low Dose Mechanism of Oral Tolerance

Patricia A. Gonnella, Hans Peter Waldner, and Howard L. Weiner
J Immunol 2001 166: 4456-4464. [Abstract] [Full Text] [PDF]  

Spontaneous and Continuous Cyclooxygenase-2-Dependent Prostaglandin E₂ Production by Stromal Cells in the Murine Small Intestine Lamina Propria: Directing the Tone of the Intestinal Immune Response

Rodney D. Newberry, Jacquelyn S. McDonough, William F. Stenson, and Robin G. Lorenz
J Immunol 2001 166: 4465-4472. [Abstract] [Full Text] [PDF]  

GIF Inhibits Th Effector Generation by Acting on Antigen-Presenting B Cells

Katsuji Sugie and Jianyong Huang
J Immunol 2001 166: 4473-4480. [Abstract] [Full Text] [PDF]  

IFN-/TNF- Synergism as the Final Effector in Autoimmune Diabetes: A Key Role for STAT1/IFN Regulatory Factor-1 Pathway in Pancreatic Cell Death

Kyoungho Suk, Sunshin Kim, Yun-Hee Kim, Kyoung-Ah Kim, Inik Chang, Hideo Yagita, Minho Shong, and Myung-Shik Lee
J Immunol 2001 166: 4481-4489. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Nonobese Diabetic Mice Display Elevated Levels of Class II-Associated Invariant Chain Peptide Associated with I-A^g7 on the Cell Surface

Aparna Bhatnagar, Peter J. Milburn, Mario Lobigs, Robert V. Blanden, and Anand M. Gautam
J Immunol 2001 166: 4490-4497. [Abstract] [Full Text] [PDF]  

Suppression of IL-12 Transcription in Macrophages Following Fc Receptor Ligation

Maria Grazia Cappiello, Fayyaz S. Sutterwala, Giorgio Trinchieri, David M. Mosser, and Xiaojing Ma
J Immunol 2001 166: 4498-4506. [Abstract] [Full Text] [PDF]  

STAT6 Mediates Eotaxin-1 Expression in IL-4 or TNF--Induced Fibroblasts

Jutta Hoeck and Maximilian Woisetschläger
J Immunol 2001 166: 4507-4515. [Abstract] [Full Text] [PDF]  

NF-B and STAT5 Play Important Roles in the Regulation of Mouse Toll-Like Receptor 2 Gene Expression

Tipayaratn Musikacharoen, Tetsuya Matsuguchi, Takeshi Kikuchi, and Yasunobu Yoshikai
J Immunol 2001 166: 4516-4524. [Abstract] [Full Text] [PDF]  

The TCR Repertoire of an Immunodominant CD8⁺ T Lymphocyte Population

Zheng W. Chen, Yunyuan Li, Xuejun Zeng, Marcelo J. Kuroda, Jöern E. Schmitz, Yun Shen, Xioamin Lai, Ling Shen, and Norman L. Letvin
J Immunol 2001 166: 4525-4533. [Abstract] [Full Text] [PDF]  

Differential Expression of Fas Ligand in Th1 and Th2 Cells Is Regulated by Early Growth Response Gene and NF-AT Family Members

Robin Dzialo-Hatton, Jeffrey Milbrandt, Richard D. Hockett, Jr., and Casey T. Weaver
J Immunol 2001 166: 4534-4542. [Abstract] [Full Text] [PDF]  

Cysteinylation of MHC Class II Ligands: Peptide Endocytosis and Reduction Within APC Influences T Cell Recognition

M. Azizul Haque, John W. Hawes, and Janice S. Blum
J Immunol 2001 166: 4543-4551. [Abstract] [Full Text] [PDF]  

NF-B p50-Dependent In Vivo Footprints at Ig S3 DNA Are Correlated with µ3 Switch Recombination

Robert A. Wuerffel, Limei Ma, and Amy L. Kenter
J Immunol 2001 166: 4552-4559. [Abstract] [Full Text] [PDF]  

HIV-1 Tat Inhibits IL-2 Gene Transcription Through Qualitative and Quantitative Alterations of the Cooperative Rel/AP1 Complex Bound to the CD28RE/AP1 Composite Element of the IL-2 Promoter

Esther González, Carmen Punzón, Manuel González, and Manuel Fresno
J Immunol 2001 166: 4560-4569. [Abstract] [Full Text] [PDF]  

Novel Androgen-Dependent Promoters Direct Expression of the C4b-Binding Protein -Chain Gene in Epididymis

Mayumi I. Nonaka, Guixian Wang, Takao Mori, Hidechika Okada, and Masaru Nonaka
J Immunol 2001 166: 4570-4577. [Abstract] [Full Text] [PDF]  

Regulation of Transcriptional Activity of the Murine CD40 Ligand Promoter in Response to Signals Through TCR and the Costimulatory Molecules CD28 and CD2

Hanna Lindgren, Karol Axcrona, and Tomas Leanderson
J Immunol 2001 166: 4578-4585. [Abstract] [Full Text] [PDF]  

Identification of a Novel Lipopolysaccharide-Inducible Gene with Key Features of Both a Kinase Anchor Proteins and chs1/beige Proteins

Jia-Wang Wang, Julie Howson, Edward Haller, and William G. Kerr
J Immunol 2001 166: 4586-4595. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Antigen-Specific Th1 But Not Th2 Cells Provide Protection from Lethal Trypanosoma cruzi Infection in Mice

Sudesh Kumar and Rick L. Tarleton
J Immunol 2001 166: 4596-4603. [Abstract] [Full Text] [PDF]  

Depletion of Alveolar Macrophages Exerts Protective Effects in Pulmonary Tuberculosis in Mice

Jaklien C. Leemans, Nicole P. Juffermans, Sandrine Florquin, Nico van Rooijen, Margriet J. Vervoordeldonk, Annelies Verbon, Sander J. H. van Deventer, and Tom van der Poll
J Immunol 2001 166: 4604-4611. [Abstract] [Full Text] [PDF]  

Cancer Vaccine Design: A Novel Bacterial Adjuvant for Peptide-Specific CTL Induction

Isabelle Miconnet, Isabelle Coste, Friedrich Beermann, Jean-François Haeuw, Jean-Charles Cerottini, Jean-Yves Bonnefoy, Pedro Romero, and Toufic Renno
J Immunol 2001 166: 4612-4619. [Abstract] [Full Text] [PDF]  

Toll-Like Receptor 4 Mediates Intracellular Signaling Without TNF- Release in Response to Cryptococcus neoformans Polysaccharide Capsule

Shmuel Shoham, Chao Huang, Jian-Min Chen, Douglas T. Golenbock, and Stuart M. Levitz
J Immunol 2001 166: 4620-4626. [Abstract] [Full Text] [PDF]  

Diversity of Epitope and Cytokine Profiles for Primary and Secondary Influenza A Virus-Specific CD8⁺ T Cell Responses

Gabrielle T. Belz, Weidong Xie, and Peter C. Doherty
J Immunol 2001 166: 4627-4633. [Abstract] [Full Text] [PDF]  

CXC Chemokine Receptor-2 Ligands Are Required for Neutrophil-Mediated Host Defense in Experimental Brain Abscesses¹

Tammy Kielian, Brenda Barry, and William F. Hickey
J Immunol 2001 166: 4634-4643. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

The ₄₁ (Very Late Antigen (VLA)-4, CD49d/CD29) and ₅₁ (VLA-5, CD49e/CD29) Integrins Mediate ₂ (CD11/CD18) Integrin-Independent Neutrophil Recruitment to Endotoxin-Induced Lung Inflammation

J. Adam Burns, Thomas B. Issekutz, Hideo Yagita, and Andrew C. Issekutz
J Immunol 2001 166: 4644-4649. [Abstract] [Full Text] [PDF]  

Human Leukocyte Subpopulations from Inflamed Gut Bind to Joint Vasculature Using Distinct Sets of Adhesion Molecules

Marko Salmi and Sirpa Jalkanen
J Immunol 2001 166: 4650-4657. [Abstract] [Full Text] [PDF]  

Granulocyte Macrophage-Colony-Stimulating Factor mRNA Is Stabilized in Airway Eosinophils and Peripheral Blood Eosinophils Activated by TNF- Plus Fibronectin

Stéphane Esnault and James S. Malter
J Immunol 2001 166: 4658-4663. [Abstract] [Full Text] [PDF]  

Evidence for a Role for SAM68 in the Responses of Human Neutrophils to Ligation of CD32 and to Monosodium Urate Crystals

Caroline Gilbert, Frédéric Barabé, Emmanuelle Rollet-Labelle, Sylvain G. Bourgoin, Shaun R. McColl, Bassam B. Damaj, and Paul H. Naccache
J Immunol 2001 166: 4664-4671. [Abstract] [Full Text] [PDF]  

An Increase in Circulating Mast Cell Colony-Forming Cells in Asthma

Hadija Hemed Mwamtemi, Kenichi Koike, Tatsuya Kinoshita, Susumu Ito, Shuichi Ishida, Yozo Nakazawa, Yumi Kurokawa, Koji Shinozaki, Kazuo Sakashita, Kouichi Takeuchi, Masaaki Shiohara, Takehiko Kamijo, Yozo Yasui, Akira Ishiguro, Yoshifumi Kawano, Kiyoshi Kitano, Hiroshi Miyazaki, Takashi Kato, Shozo Sakuma, and Atsushi Komiyama
J Immunol 2001 166: 4672-4677. [Abstract] [Full Text] [PDF]  

Two Proteins Modulating Transendothelial Migration of Leukocytes Recognize Novel Carboxylated Glycans on Endothelial Cells

Geetha Srikrishna, Krishnasamy Panneerselvam, Vibeke Westphal, Violet Abraham, Ajit Varki, and Hudson H. Freeze
J Immunol 2001 166: 4678-4688. [Abstract] [Full Text] [PDF]  

The Expression of Prostaglandin E Receptors EP₂ and EP₄ and Their Different Regulation by Lipopolysaccharide in C3H/HeN Peritoneal Macrophages

Reiko Ikegami, Yukihiko Sugimoto, Eri Segi, Masato Katsuyama, Hisae Karahashi, Fumio Amano, Takayuki Maruyama, Hana Yamane, Soken Tsuchiya, and Atsushi Ichikawa
J Immunol 2001 166: 4689-4696. [Abstract] [Full Text] [PDF]  

Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice

Matthias Mack, Josef Cihak, Christopher Simonis, Bruno Luckow, Amanda E. I. Proudfoot, Hilke Brühl, Michael Frink, Hans-Joachim Anders, Volker Vielhauer, Jochen Pfirstinger, Manfred Stangassinger, and Detlef Schlöndorff
J Immunol 2001 166: 4697-4704. [Abstract] [Full Text] [PDF]  

A Comparison of Mediators Released or Generated by IFN--Treated Human Mast Cells Following Aggregation of FcRI or FcRI

Yoshimichi Okayama, David D. Hagaman, and Dean D. Metcalfe
J Immunol 2001 166: 4705-4712. [Abstract] [Full Text] [PDF]  

Lipopolysaccharide Activates Akt in Human Alveolar Macrophages Resulting in Nuclear Accumulation and Transcriptional Activity of -Catenin

Martha M. Monick, A. Brent Carter, Pamela K. Robeff, Dawn M. Flaherty, Michael W. Peterson, and Gary W. Hunninghake
J Immunol 2001 166: 4713-4720. [Abstract] [Full Text] [PDF]  

Requirement of A1-a for Bacillus Calmette-Guérin-Mediated Protection of Macrophages Against Nitric Oxide-Induced Apoptosis

Santhanam Kausalya, Robert Somogyi, Amos Orlofsky, and Michael B. Prystowsky
J Immunol 2001 166: 4721-4727. [Abstract] [Full Text] [PDF]  

Macrophages Transfected with Adenovirus to Express IL-4 Reduce Inflammation in Experimental Glomerulonephritis

David C. Kluth, Clare V. Ainslie, Wayne P. Pearce, Sian Finlay, Daniel Clarke, Ignacio Anegon, and Andrew J. Rees
J Immunol 2001 166: 4728-4736. [Abstract] [Full Text] [PDF]  

Reduced Early Alcohol-Induced Liver Injury in CD14-Deficient Mice

Ming Yin, Blair U. Bradford, Michael D. Wheeler, Takehiko Uesugi, Matthias Froh, Sanna M. Goyert, and Ronald G. Thurman
J Immunol 2001 166: 4737-4742. [Abstract] [Full Text] [PDF]  

Nonphlogistic Clearance of Late Apoptotic Neutrophils by Macrophages: Efficient Phagocytosis Independent of ₂ Integrins

Yi Ren, Lynda Stuart, Frederik P. Lindberg, Alexander R. Rosenkranz, Yongmei Chen, Tanya N. Mayadas, and John Savill
J Immunol 2001 166: 4743-4750. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

T Cells of Multiple Sclerosis Patients Target a Common Environmental Peptide that Causes Encephalitis in Mice

Shawn Winer, Igor Astsaturov, Roy K. Cheung, Katrin Schrade, Lakshman Gunaratnam, Denise D. Wood, Mario A. Moscarello, Paul O’Connor, Colin McKerlie, Dorothy J. Becker, and Hans-Michael Dosch
J Immunol 2001 166: 4751-4756. [Abstract] [Full Text] [PDF]  

Frequencies of Neuroantigen-Specific T Cells in the Central Nervous System Versus the Immune Periphery During the Course of Experimental Allergic Encephalomyelitis

Oleg S. Targoni, Jan Baus, Harald H. Hofstetter, Maike D. Hesse, Alexey Y. Karulin, Bernhard O. Boehm, Thomas G. Forsthuber, and Paul V. Lehmann
J Immunol 2001 166: 4757-4764. [Abstract] [Full Text] [PDF]  

Persistence of Pathogenic CD4⁺ Th1-Like Cells In Vivo in the Absence of IL-12 but in the Presence of Autoantigen

Kenneth Hong, Ellen L. Berg, and Rolf O. Ehrhardt
J Immunol 2001 166: 4765-4772. [Abstract] [Full Text] [PDF]  

Specific Immunotherapy by Genetically Engineered APCs: The "Guided Missile" Strategy

Bo Wu, Jian-Ming Wu, Alexei Miagkov, Robert N. Adams, Hyam I. Levitsky, and Daniel B. Drachman
J Immunol 2001 166: 4773-4779. [Abstract] [Full Text] [PDF]  

Reactivity of Anti-Proliferating Cell Nuclear Antigen (PCNA) Murine Monoclonal Antibodies and Human Autoantibodies to the PCNA Multiprotein Complexes Involved in Cell Proliferation

Yoshinari Takasaki, Toshiaki Kogure, Ken Takeuchi, Kazuhiko Kaneda, Tetsuro Yano, Kaoru Hirokawa, Sachiko Hirose, Toshikazu Shirai, and Hiroshi Hashimoto
J Immunol 2001 166: 4780-4787. [Abstract] [Full Text] [PDF]  

ERRATA:

Correction

J Immunol 2001 166: 4788. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.