CUTTING EDGE:

Cutting Edge: C-C Chemokine Receptor 6 Is Essential for Arrest of a Subset of Memory T Cells on Activated Dermal Microvascular Endothelial Cells Under Physiologic Flow Conditions In Vitro

David J. Fitzhugh, Shubhada Naik, S. Wright Caughman, and Sam T. Hwang
J Immunol 2000 165: 6677-6681. [Abstract] [Full Text] [PDF]  

Cutting Edge: Naturally Occurring Soluble Form of Mouse Toll-Like Receptor 4 Inhibits Lipopolysaccharide Signaling

Ken-ichiro Iwami, Tetsuya Matsuguchi, Akio Masuda, Takeshi Kikuchi, Tipayaratn Musikacharoen, and Yasunobu Yoshikai
J Immunol 2000 165: 6682-6686. [Abstract] [Full Text] [PDF]  

Cutting Edge: Chromatin Remodeling at the IL-4/IL-13 Intergenic Regulatory Region for Th2-Specific Cytokine Gene Cluster

Naofumi Takemoto, Yumiko Kamogawa, Hyun Jun Lee, Hirokazu Kurata, Ken-ichi Arai, Anne O’Garra, Naoko Arai, and Shoichiro Miyatake
J Immunol 2000 165: 6687-6691. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

CDK4 Expression and Activity Are Required for Cytokine Responsiveness in T Cells

Jaime F. Modiano, Jocelyne Mayor, Carrie Ball, Maren K. Fuentes, and D. Scott Linthicum
J Immunol 2000 165: 6693-6702. [Abstract] [Full Text] [PDF]  

CD30 Shedding from Karpas 299 Lymphoma Cells Is Mediated by TNF--Converting Enzyme

Hinrich P. Hansen, Sebastian Dietrich, Tatiana Kisseleva, Thilo Mokros, Rolf Mentlein, Hans H. Lange, Gillian Murphy, and Hilmar Lemke
J Immunol 2000 165: 6703-6709. [Abstract] [Full Text] [PDF]  

MHC Recognition in Thymic Development: Distinct, Parallel Pathways for Survival and Lineage Commitment

David Chang, Patricia Valdez, Thomas Ho, and Ellen Robey
J Immunol 2000 165: 6710-6715. [Abstract] [Full Text] [PDF]  

Intestinal CD8 and CD8ß Intraepithelial Lymphocytes Are Thymus Derived and Exhibit Subtle Differences in TCRß Repertoires

Beat A. Imhof, Dominique Dunon, David Courtois, Marko Luhtala, and Olli Vainio
J Immunol 2000 165: 6716-6722. [Abstract] [Full Text] [PDF]  

Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes

Elisa Apolloni, Vincenzo Bronte, Alessandra Mazzoni, Paolo Serafini, Anna Cabrelle, David M. Segal, Howard A. Young, and Paola Zanovello
J Immunol 2000 165: 6723-6730. [Abstract] [Full Text] [PDF]  

Reversal of CD8⁺ T Cell Ignorance and Induction of Anti-Tumor Immunity by Peptide-Pulsed APC

Nava Dalyot-Herman, Oliver F. Bathe, and Thomas R. Malek
J Immunol 2000 165: 6731-6737. [Abstract] [Full Text] [PDF]  

Targeting Weak Antigens to CD64 Elicits Potent Humoral Responses in Human CD64 Transgenic Mice

Tibor Keler, Paul M. Guyre, Laura A. Vitale, Karuna Sundarapandiyan, Jan G. J. van de Winkel, Yashwant M. Deo, and Robert F. Graziano
J Immunol 2000 165: 6738-6742. [Abstract] [Full Text] [PDF]  

Dendritic Cell Migration Controlled by _1b-Adrenergic Receptors

Georges J. M. Maestroni
J Immunol 2000 165: 6743-6747. [Abstract] [Full Text] [PDF]  

Early Th1 Response in Unprimed Nonobese Diabetic Mice to the Tyrosine Phosphatase-Like Insulinoma-Associated Protein 2, an Autoantigen in Type 1 Diabetes

Sylvie Trembleau, Giuseppe Penna, Silvia Gregori, Giovanni Magistrelli, Antonella Isacchi, and Luciano Adorini
J Immunol 2000 165: 6748-6755. [Abstract] [Full Text] [PDF]  

Resistance to TNF-Induced Cytotoxicity Correlates with an Abnormal Cleavage of Cytosolic Phospholipase A₂

Nour-Eddine El Mahdani, Maya Ameyar, Zhenzi Cai, Odile Colard, Joëlle Masliah, and Salem Chouaib
J Immunol 2000 165: 6756-6761. [Abstract] [Full Text] [PDF]  

The Development, Maturation, and Turnover Rate of Mouse Spleen Dendritic Cell Populations

Arun T. Kamath, Joanne Pooley, Meredith A. O’Keeffe, David Vremec, Yifan Zhan, Andrew M. Lew, Angela D’Amico, Li Wu, David F. Tough, and Ken Shortman
J Immunol 2000 165: 6762-6770. [Abstract] [Full Text] [PDF]  

Exposure to Cigarette Tar Inhibits Ribonucleotide Reductase and Blocks Lymphocyte Proliferation

Jesica M. McCue, Karen L. Link, Sandra S. Eaton, and Brian M. Freed
J Immunol 2000 165: 6771-6775. [Abstract] [Full Text] [PDF]  

HLA-B2702 (77–83/83–77) Peptide Binds to ß-Tubulin on Human NK Cells and Blocks Their Cytotoxic Capacity

Raquel Tarazona, Guillermo López-Lluch, Maria-Dolores Galiani, Enrique Aguado, Fernando Barahona, Rafael Solana, and José Peña
J Immunol 2000 165: 6776-6782. [Abstract] [Full Text] [PDF]  

CD4⁺ Th1 and CD8⁺ Type 1 Cytotoxic T Cells Both Play a Crucial Role in the Full Development of Contact Hypersensitivity

Binghe Wang, Hiroshi Fujisawa, Lihua Zhuang, Irwin Freed, Brandon G. Howell, Shabana Shahid, Gulnar M. Shivji, Tak W. Mak, and Daniel N. Sauder
J Immunol 2000 165: 6783-6790. [Abstract] [Full Text] [PDF]  

Functional Equivalency of B7-1 and B7-2 for Costimulating Plasmid DNA Vaccine-Elicited CTL Responses

Sampa Santra, Dan H. Barouch, Shawn S. Jackson, Marcelo J. Kuroda, Joern E. Schmitz, Michelle A. Lifton, Arlene H. Sharpe, and Norman L. Letvin
J Immunol 2000 165: 6791-6795. [Abstract] [Full Text] [PDF]  

Ig Light Chain Receptor Editing in Anergic B Cells

Lina E. Tze, Elizabeth A. Baness, Keli L. Hippen, and Timothy W. Behrens
J Immunol 2000 165: 6796-6802. [Abstract] [Full Text] [PDF]  

Stat4 Regulates Multiple Components of IFN--Inducing Signaling Pathways

Victoria A. Lawless, Shangming Zhang, Osman N. Ozes, Heather A. Bruns, India Oldham, Timothy Hoey, Michael J. Grusby, and Mark H. Kaplan
J Immunol 2000 165: 6803-6808. [Abstract] [Full Text] [PDF]  

Ligation of CD27 on Murine B Cells Responding to T-Dependent and T-Independent Stimuli Inhibits the Generation of Plasma Cells

Vanitha S. Raman, Vineeta Bal, Satyajit Rath, and Anna George
J Immunol 2000 165: 6809-6815. [Abstract] [Full Text] [PDF]  

Diminution of the AML1 Transcription Factor Function Causes Differential Effects on the Fates of CD4 and CD8 Single-Positive T Cells

Keitaro Hayashi, Waka Natsume, Toshio Watanabe, Natsumi Abe, Naomi Iwai, Hitoshi Okada, Yoshiaki Ito, Masahide Asano, Yoichiro Iwakura, Sonoko Habu, Yousuke Takahama, and Masanobu Satake
J Immunol 2000 165: 6816-6824. [Abstract] [Full Text] [PDF]  

Genetic Analyses of NFKB1 and OCA-B Function: Defects in B Cells, Serum IgM Level, and Antibody Responses in Nfkb1^-/-Oca-b^-/- Mice

Unkyu Kim, Cary S. Gunther, and Robert G. Roeder
J Immunol 2000 165: 6825-6832. [Abstract] [Full Text] [PDF]  

Early Programming of T Cell Populations Responding to Bacterial Infection

Roberto Mercado, Sujata Vijh, S. Elise Allen, Kristen Kerksiek, Ingrid M. Pilip, and Eric G. Pamer
J Immunol 2000 165: 6833-6839. [Abstract] [Full Text] [PDF]  

B7 Requirements for Primary and Secondary Protein- and Polysaccharide-Specific Ig Isotype Responses to Streptococcus pneumoniae

Zheng-Qi Wu, Abdul Q. Khan, Yi Shen, Jerome Schartman, Robert Peach, Andrew Lees, James J. Mond, William C. Gause, and Clifford M. Snapper
J Immunol 2000 165: 6840-6848. [Abstract] [Full Text] [PDF]  

Genetic Characterization of Strain Differences in the Ability to Mediate CD40/CD28-Independent Rejection of Skin Allografts

Matthew A. Williams, Joel Trambley, Jongwon Ha, Andrew B. Adams, Megan M. Durham, Phyllis Rees, Shannon R. Cowan, Thomas C. Pearson, and Christian P. Larsen
J Immunol 2000 165: 6849-6857. [Abstract] [Full Text] [PDF]  

Reactivity and Regulatory Properties of Human Anti-Idiotypic Antibodies Induced by T Cell Vaccination

Jian Hong, Ying C. Q. Zang, Maria V. Tejada-Simon, Sufang Li, Victor M. Rivera, James Killian, and Jingwu Z. Zhang
J Immunol 2000 165: 6858-6864. [Abstract] [Full Text] [PDF]  

Evidence for Protein Kinase C-Dependent and -Independent Activation of Mitogen-Activated Protein Kinase in T Cells: Potential Role of Additional Diacylglycerol Binding Proteins

Lawrence G. Puente, James C. Stone, and Hanne L. Ostergaard
J Immunol 2000 165: 6865-6871. [Abstract] [Full Text] [PDF]  

The c-Abl Tyrosine Kinase Is Regulated Downstream of the B Cell Antigen Receptor and Interacts with CD19

Patricia A. Zipfel, Matthew Grove, Kevin Blackburn, Manabu Fujimoto, Thomas F. Tedder, and Ann Marie Pendergast
J Immunol 2000 165: 6872-6879. [Abstract] [Full Text] [PDF]  

Expression and Function of IL-12 and IL-18 Receptors on Human Tonsillar B Cells

Irma Airoldi, Giorgia Gri, Jason D. Marshall, Anna Corcione, Paola Facchetti, Roberta Guglielmino, Giorgio Trinchieri, and Vito Pistoia
J Immunol 2000 165: 6880-6888. [Abstract] [Full Text] [PDF]  

CpG DNA Induces Maturation of Dendritic Cells with Distinct Effects on Nascent and Recycling MHC-II Antigen-Processing Mechanisms

David Askew, Rose S. Chu, Arthur M. Krieg, and Clifford V. Harding
J Immunol 2000 165: 6889-6895. [Abstract] [Full Text] [PDF]  

Negative Regulation of CD8⁺ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR

Suzanne Kadereit, Hui Xu, Tara M. Engeman, Yi-Li Yang, Robert L. Fairchild, and Bryan R. G. Williams
J Immunol 2000 165: 6896-6901. [Abstract] [Full Text] [PDF]  

Receptor Revision in Peripheral T Cells Creates a Diverse Vß Repertoire

Catherine J. McMahan and Pamela J. Fink
J Immunol 2000 165: 6902-6907. [Abstract] [Full Text] [PDF]  

Costimulation Light: Activation of CD4⁺ T Cells with CD80 or CD86 Rather Than Anti-CD28 Leads to a Th2 Cytokine Profile

Chris P. M. Broeren, Gary S. Gray, Beatriz M. Carreno, and Carl H. June
J Immunol 2000 165: 6908-6914. [Abstract] [Full Text] [PDF]  

A Role for CD21/CD35 and CD19 in Responses to Acute Septic Peritonitis: A Potential Mechanism for Mast Cell Activation

Jennifer L. Gommerman, David Y. Oh, Xiaoning Zhou, Thomas F. Tedder, Marcus Maurer, Stephen J. Galli, and Michael C. Carroll
J Immunol 2000 165: 6915-6921. [Abstract] [Full Text] [PDF]  

Mapping the Ligand of the NK Inhibitory Receptor Ly49A on Living Cells

Doo Hyun Chung, Kannan Natarajan, Lisa F. Boyd, José Tormo, Roy A. Mariuzza, Wayne M. Yokoyama, and David H. Margulies
J Immunol 2000 165: 6922-6932. [Abstract] [Full Text] [PDF]  

The Physical Association of Protein Kinase C with a Lipid Raft-Associated Inhibitor of B Factor Kinase (IKK) Complex Plays a Role in the Activation of the NF-B Cascade by TCR and CD28

Ali Khoshnan, David Bae, Charles A. Tindell, and Andre E. Nel
J Immunol 2000 165: 6933-6940. [Abstract] [Full Text] [PDF]  

Peroxisome Proliferator Activator Receptor- Agonists and 15-Deoxy-^12,1412,14-PGJ₂ Induce Apoptosis in Normal and Malignant B-Lineage Cells

Josué Padilla, Kuljeet Kaur, H. James Cao, Terry J. Smith, and Richard P. Phipps
J Immunol 2000 165: 6941-6948. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Crystal Structure of an Antibody Bound to an Immunodominant Peptide Epitope: Novel Features in Peptide-Antibody Recognition

Deepak T. Nair, Kavita Singh, Naresh Sahu, Kanury V. S. Rao, and Dinakar M. Salunke
J Immunol 2000 165: 6949-6955. [Abstract] [Full Text] [PDF]  

The Transcription Factor Bright Associates with Bruton’s Tyrosine Kinase, the Defective Protein in Immunodeficiency Disease

Carol F. Webb, Yoshio Yamashita, Neil Ayers, Seth Evetts, Yolene Paulin, Mary Ellen Conley, and Elizabeth A. Smith
J Immunol 2000 165: 6956-6965. [Abstract] [Full Text] [PDF]  

Identification of Fetal Liver Tyrosine Kinase 3 (Flt3) Ligand Domain Required for Receptor Binding and Function Using Naturally Occurring Ligand Isoforms

Waithaka Mwangi, Wendy C. Brown, and Guy H. Palmer
J Immunol 2000 165: 6966-6974. [Abstract] [Full Text] [PDF]  

The Murine IL-2 Promoter Contains Distal Regulatory Elements Responsive to the Ah Receptor, a Member of the Evolutionarily Conserved bHLH-PAS Transcription Factor Family

Myung-Shin Jeon and Charlotte Esser
J Immunol 2000 165: 6975-6983. [Abstract] [Full Text] [PDF]  

Conservation of Mhc Class III Region Synteny Between Zebrafish and Human as Determined by Radiation Hybrid Mapping

Holger Sültmann, Akie Sato, Brent W. Murray, Naoko Takezaki, Robert Geisler, Gerd-Jörg Rauch, and Jan Klein
J Immunol 2000 165: 6984-6993. [Abstract] [Full Text] [PDF]  

Distinct T Cell Interactions with HLA Class II Tetramers Characterize a Spectrum of TCR Affinities in the Human Antigen-Specific T Cell Response

Sandra Reichstetter, Ruth A. Ettinger, Andrew W. Liu, John A. Gebe, Gerald T. Nepom, and William W. Kwok
J Immunol 2000 165: 6994-6998. [Abstract] [Full Text] [PDF]  

Antibody Repertoire Development in Fetal and Neonatal Piglets. II. Characterization of Heavy Chain Complementarity-Determining Region 3 Diversity in the Developing Fetus

J. E. Butler, P. Weber, M. Sinkora, J. Sun, S. J. Ford, and R. K. Christenson
J Immunol 2000 165: 6999-7010. [Abstract] [Full Text] [PDF]  

Delineation of the Human Systemic Lupus Erythematosus Anti-Smith Antibody Response Using Phage-Display Combinatorial Libraries

Inmaculada del Rincon, Maria Zeidel, Elena Rey, John B. Harley, Judith A. James, Michael Fischbach, and Iñaki Sanz
J Immunol 2000 165: 7011-7016. [Abstract] [Full Text] [PDF]  

Activation of MHC Class I, II, and CD40 Gene Expression by Histone Deacetylase Inhibitors

William J. Magner, A. Latif Kazim, Carleton Stewart, Michelle A. Romano, Geoffrey Catalano, Catherine Grande, Nicholas Keiser, Frank Santaniello, and Thomas B. Tomasi
J Immunol 2000 165: 7017-7024. [Abstract] [Full Text] [PDF]  

Factors Controlling the Trafficking and Processing of a Leader-Derived Peptide Presented by Qa-1

Ailin Bai, Carla J. Aldrich, and James Forman
J Immunol 2000 165: 7025-7034. [Abstract] [Full Text] [PDF]  

HIV-1 Tat Represses Transcription from the Mannose Receptor Promoter

Robert L. Caldwell, Brian S. Egan, and Virginia L. Shepherd
J Immunol 2000 165: 7035-7041. [Abstract] [Full Text] [PDF]  

Two Different Epitopes of the Signal Transducer gp130 Sequentially Cooperate on IL-6-Induced Receptor Activation

Stefan Pflanz, Ingo Kurth, Joachim Grötzinger, Peter C. Heinrich, and Gerhard Müller-Newen
J Immunol 2000 165: 7042-7049. [Abstract] [Full Text] [PDF]  

Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives

Reinhilde Schoonjans, An Willems, Steve Schoonooghe, Walter Fiers, Johan Grooten, and Nico Mertens
J Immunol 2000 165: 7050-7057. [Abstract] [Full Text] [PDF]  

Induced Receptor Editing Shows No Allelic Preference in a Mouse Pre-B Cell Line

Xiangdong Liu, Michael Linden, and Brian Van Ness
J Immunol 2000 165: 7058-7063. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Immunization with a Recombinant Stage-Regulated Surface Protein from Leishmania donovani Induces Protection Against Visceral Leishmaniasis

Simona Stäger, Deborah F. Smith, and Paul M. Kaye
J Immunol 2000 165: 7064-7071. [Abstract] [Full Text] [PDF]  

A Mechanism for the Impaired IFN- Production in C-C Chemokine Receptor 2 (CCR2) Knockout Mice: Role of CCR2 in Linking the Innate and Adaptive Immune Responses

Wendy Peters, Marc Dupuis, and Israel F. Charo
J Immunol 2000 165: 7072-7077. [Abstract] [Full Text] [PDF]  

The Importance of Exogenous Antigen in Priming the Human CD8⁺ T Cell Response: Lessons from the EBV Nuclear Antigen EBNA1

Neil Blake, Tracey Haigh, Ghadeer Shaka’a, Debbie Croom-Carter, and Alan Rickinson
J Immunol 2000 165: 7078-7087. [Abstract] [Full Text] [PDF]  

Human CD8⁺ CTL Specific for the Mycobacterial Major Secreted Antigen 85A

Steven M. Smith, Roger Brookes, Michèl R. Klein, Adam S. Malin, Pauline T. Lukey, Abigail S. King, Graham S. Ogg, Adrian V. S. Hill, and Hazel M. Dockrell
J Immunol 2000 165: 7088-7095. [Abstract] [Full Text] [PDF]  

Synergy and Cross-Tolerance Between Toll-Like Receptor (TLR) 2- and TLR4-Mediated Signaling Pathways

Shintaro Sato, Fumiko Nomura, Taro Kawai, Osamu Takeuchi, Peter F. Mühlradt, Kiyoshi Takeda, and Shizuo Akira
J Immunol 2000 165: 7096-7101. [Abstract] [Full Text] [PDF]  

Granulysin, a T Cell Product, Kills Bacteria by Altering Membrane Permeability

William A. Ernst, Sybille Thoma-Uszynski, Rachel Teitelbaum, Christine Ko, Dennis A. Hanson, Carol Clayberger, Alan M. Krensky, Matthias Leippe, Barry R. Bloom, Tomas Ganz, and Robert L. Modlin
J Immunol 2000 165: 7102-7108. [Abstract] [Full Text] [PDF]  

IL-12-Activated NK Cells Reduce Lung Eosinophilia to the Attachment Protein of Respiratory Syncytial Virus But Do Not Enhance the Severity of Illness in CD8 T Cell-Immunodeficient Conditions

Tracy Hussell and Peter J. M. Openshaw
J Immunol 2000 165: 7109-7115. [Abstract] [Full Text] [PDF]  

T Cell-Mediated Tumor Rejection Displays Diverse Dependence Upon Perforin and IFN- Mechanisms That Cannot Be Predicted From In Vitro T Cell Characteristics

Liaomin Peng, John C. Krauss, Gregory E. Plautz, Shigehiko Mukai, Suyu Shu, and Peter A. Cohen
J Immunol 2000 165: 7116-7124. [Abstract] [Full Text] [PDF]  

Evidence for an Accessory Protein Function for Toll-Like Receptor 1 in Anti-Bacterial Responses

D. H. Wyllie, E. Kiss-Toth, A. Visintin, S. C. Smith, S. Boussouf, D. M. Segal, G. W. Duff, and S. K. Dower
J Immunol 2000 165: 7125-7132. [Abstract] [Full Text] [PDF]  

V9V2 T Cells Impair Intracellular Multiplication of Brucella suis in Autologous Monocytes Through Soluble Factor Release and Contact-Dependent Cytotoxic Effect

Florence Ottones, Jacques Dornand, Aroem Naroeni, Jean-Pierre Liautard, and Jean Favero
J Immunol 2000 165: 7133-7139. [Abstract] [Full Text] [PDF]  

T Cell Expression Cloning of a Mycobacterium tuberculosis Gene Encoding a Protective Antigen Associated with the Early Control of Infection

Yasir A. W. Skeiky, Pamela J. Ovendale, Shyian Jen, Mark R. Alderson, Davin C. Dillon, Sherilyn Smith, Christopher B. Wilson, Ian M. Orme, Steven G. Reed, and Antonio Campos-Neto
J Immunol 2000 165: 7140-7149. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Inhibition of TNF- Produced by Kupffer Cells Protects Against the Nonspecific Liver Toxicity of Immunotoxin Anti-Tac(Fv)-PE38, LMB-2

Masanori Onda, Mark Willingham, Qing-cheng Wang, Robert J. Kreitman, Yasuo Tsutsumi, Satoshi Nagata, and Ira Pastan
J Immunol 2000 165: 7150-7156. [Abstract] [Full Text] [PDF]  

Molecular Mechanisms of High-Dose Antigen Therapy in Experimental Autoimmune Encephalomyelitis: Rapid Induction of Th1-Type Cytokines and Inducible Nitric Oxide Synthase

Andreas Weishaupt, Sebastian Jander, Wolfgang Brück, Tanja Kuhlmann, Martina Stienekemeier, Thomas Hartung, Klaus V. Toyka, Guido Stoll, and Ralf Gold
J Immunol 2000 165: 7157-7163. [Abstract] [Full Text] [PDF]  

L-Selectin Facilitates Emigration and Extravascular Locomotion of Leukocytes During Acute Inflammatory Responses In Vivo

Michael J. Hickey, Melanie Forster, Debra Mitchell, Jaswinder Kaur, Catherine De Caigny, and Paul Kubes
J Immunol 2000 165: 7164-7170. [Abstract] [Full Text] [PDF]  

Tat Protein Is an HIV-1-Encoded ß-Chemokine Homolog That Promotes Migration and Up-Regulates CCR3 Expression on Human FcRI⁺ Cells

Amato de Paulis, Raffaele De Palma, Luisa Di Gioia, Maria Carfora, Nella Prevete, Giovanna Tosi, Roberto S. Accolla, and Gianni Marone
J Immunol 2000 165: 7171-7179. [Abstract] [Full Text] [PDF]  

Vitamin C Inhibits NF-B Activation by TNF Via the Activation of p38 Mitogen-Activated Protein Kinase

Andrew G. Bowie and Luke A. J. O’Neill
J Immunol 2000 165: 7180-7188. [Abstract] [Full Text] [PDF]  

Endotoxin Activation of Macrophages Does Not Induce ATP Release and Autocrine Stimulation of P2 Nucleotide Receptors

Reza D. Beigi and George R. Dubyak
J Immunol 2000 165: 7189-7198. [Abstract] [Full Text] [PDF]  

Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-B But Not C/EBPß or c-Jun

Constantinos Georganas, Hongtao Liu, Harris Perlman, Alexander Hoffmann, Bayar Thimmapaya, and Richard M. Pope
J Immunol 2000 165: 7199-7206. [Abstract] [Full Text] [PDF]  

The Efficacy of Immunotherapy in an Experimental Murine Model of Allergic Asthma Is Related to the Strength and Site of T Cell Activation During Immunotherapy

Edith M. Janssen, Antoon J. M. van Oosterhout, Frans P. Nijkamp, Willem van Eden, and Marca H. M. Wauben
J Immunol 2000 165: 7207-7214. [Abstract] [Full Text] [PDF]  

Chemokine Production by G Protein-Coupled Receptor Activation in a Human Mast Cell Line: Roles of Extracellular Signal-Regulated Kinase and NFAT

Hydar Ali, Jasimuddin Ahamed, Cristina Hernandez-Munain, Jonathan L. Baron, Michael S. Krangel, and Dhavalkumar D. Patel
J Immunol 2000 165: 7215-7223. [Abstract] [Full Text] [PDF]  

Basophil Responses to Chemokines Are Regulated by Both Sequential and Cooperative Receptor Signaling

Akos Heinemann, Adele Hartnell, Victoria E. L. Stubbs, Kazuki Murakami, Dulce Soler, Gregory LaRosa, Philip W. Askenase, Timothy J. Williams, and Ian Sabroe
J Immunol 2000 165: 7224-7233. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Up-Regulation of the IL-12 Receptor ß2 Chain in Crohn’s Disease

Tiziana Parrello, Giovanni Monteleone, Salvatore Cucchiara, Ivan Monteleone, Ladislava Sebkova, Patrizia Doldo, Francesco Luzza, and Francesco Pallone
J Immunol 2000 165: 7234-7239. [Abstract] [Full Text] [PDF]  

Evaluation of TNF- and IL-1 Blockade in Collagen-Induced Arthritis and Comparison with Combined Anti-TNF-/Anti-CD4 Therapy

Richard O. Williams, Lilia Marinova-Mutafchieva, Marc Feldmann, and Ravinder N. Maini
J Immunol 2000 165: 7240-7245. [Abstract] [Full Text] [PDF]  

Adenoviral Transfer of Cyclin-Dependent Kinase Inhibitor Genes Suppresses Collagen-Induced Arthritis in Mice

Kimio Nasu, Hitoshi Kohsaka, Yoshinori Nonomura, Yoshio Terada, Hiroshi Ito, Katsuiku Hirokawa, and Nobuyuki Miyasaka
J Immunol 2000 165: 7246-7252. [Abstract] [Full Text] [PDF]  

Efficient Simultaneous Presentation of NY-ESO-1/LAGE-1 Primary and Nonprimary Open Reading Frame-Derived CTL Epitopes in Melanoma

Donata Rimoldi, Verena Rubio-Godoy, Valerie Dutoit, Danielle Lienard, Suzanne Salvi, Philippe Guillaume, Daniel Speiser, Elisabeth Stockert, Giulio Spagnoli, Catherine Servis, Jean-Charles Cerottini, Ferdy Lejeune, Pedro Romero, and Danila Valmori
J Immunol 2000 165: 7253-7261. [Abstract] [Full Text] [PDF]  

Early Requirement for B Cells for Development of Spontaneous Autoimmune Thyroiditis in NOD.H-2h4 Mice

Helen Braley-Mullen and Shiguang Yu
J Immunol 2000 165: 7262-7269. [Abstract] [Full Text] [PDF]  

Highly Autoproliferative T Cells Specific for 60-kDa Heat Shock Protein Produce IL-4/IL-10 and IFN- and Are Protective in Adjuvant Arthritis

Alberta G. A. Paul, Peter J. S. van Kooten, Willem van Eden, and Ruurd van der Zee
J Immunol 2000 165: 7270-7277. [Abstract] [Full Text] [PDF]  

The Influence of HLA Class I Alleles and Heterozygosity on the Outcome of Human T Cell Lymphotropic Virus Type I Infection

Katie J. M. Jeffery, Asna A. Siddiqui, Mike Bunce, Alun L. Lloyd, Alison M. Vine, Aviva D. Witkover, Shuji Izumo, Koichiro Usuku, Kenneth I. Welsh, Mitsuhiro Osame, and Charles R. M. Bangham
J Immunol 2000 165: 7278-7284. [Abstract] [Full Text] [PDF]  

Direct Detection and Magnetic Isolation of Chlamydia trachomatis Major Outer Membrane Protein-Specific CD8⁺ CTLs with HLA Class I Tetramers

Seon-Kyeong Kim, Lesley Devine, Mark Angevine, Robert DeMars, and Paula B. Kavathas
J Immunol 2000 165: 7285-7292. [Abstract] [Full Text] [PDF]  

IL-12 Treatment of Endogenously Arising Murine Brain Tumors

Edward J. Roy, Ute Gawlick, Brent A. Orr, Laurie A. Rund, Andrew G. Webb, and David M. Kranz
J Immunol 2000 165: 7293-7299. [Abstract] [Full Text] [PDF]  

Human and Murine CD4 T Cell Reactivity to a Complex Antigen: Recognition of the Synthetic Random Polypeptide Glatiramer Acetate

Petra W. Duda, Jeffrey I. Krieger, Mascha C. Schmied, Courtney Balentine, and David A. Hafler
J Immunol 2000 165: 7300-7307. [Abstract] [Full Text] [PDF]  

Adoptive T Cell Immunotherapy of Human Uveal Melanoma Targeting gp100

Roger P. M. Sutmuller, Luc R. H. M. Schurmans, Leonie M. van Duivenvoorde, John A. Tine, Ellen I. H. van der Voort, René E. M. Toes, Cornelis J. M. Melief, Martine J. Jager, and Rienk Offringa
J Immunol 2000 165: 7308-7315. [Abstract] [Full Text] [PDF]  

CD40 Signaling Replaces CD4⁺ Lymphocytes and Its Blocking Prevents Chronic Rejection of Heart Transplants

Michael P. Fischbein, Abbas Ardehali, James Yun, Stephen Schoenberger, Hillel Laks, Yoshihito Irie, Paul Dempsey, Genhong Cheng, Michael C. Fishbein, and Benjamin Bonavida
J Immunol 2000 165: 7316-7322. [Abstract] [Full Text] [PDF]  

Tyrosinase Family Proteins Are Antigens Specific to Vogt-Koyanagi-Harada Disease

Kunihiko Yamaki, Kiyoko Gocho, Koichi Hayakawa, Isao Kondo, and Shozo Sakuragi
J Immunol 2000 165: 7323-7329. [Abstract] [Full Text] [PDF]  

A Mechanism for IL-10-Mediated Diabetes in the Nonobese Diabetic (NOD) Mouse: ICAM-1 Deficiency Blocks Accelerated Diabetes

Balaji Balasa, Antonio La Cava, Kurt Van Gunst, Lorraine Mocnik, Deepika Balakrishna, Nancy Nguyen, Lee Tucker, and Nora Sarvetnick
J Immunol 2000 165: 7330-7337. [Abstract] [Full Text] [PDF]  

AD HOC REVIEWERS

J Immunol 2000 165: 7342-7348. [Full Text] [PDF]  

ERRATA:

Correction for vol. 165, p. 5352

J Immunol 2000 165: 7338. [Full Text] [PDF]  

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