The JI -- Table of Contents (163 [9])

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PRESIDENTIAL ADDRESS:

Presidential Address to The American Association of Immunologists : Stimulating Naive T Cells: Jonathan Sprent
J Immunol 1999 163: 4629-4636. [Abstract] [Full Text] [PDF]

CUTTING EDGE:

Cutting Edge: Ig Heavy Chain 3' HS1–4 Directs Correct Spatial Position-Independent Expression of a Linked Transgene to B Lineage Cells: Christine Chauveau, Emmelie Å. Jansson, Susanne Müller, Michel Cogné, and Sven Pettersson
J Immunol 1999 163: 4637-4641. [Abstract] [Full Text] [PDF]

Cutting Edge: Role of C-C Chemokine Receptor 5 in Organ-Specific and Innate Immunity to Cryptococcus neoformans: Gary B. Huffnagle, Lisa K. McNeil, Roderick A. McDonald, Juneann W. Murphy, Galen B. Toews, Nobuyo Maeda, and William A. Kuziel
J Immunol 1999 163: 4642-4646. [Abstract] [Full Text] [PDF]

Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells: Claude Carnaud, Daniel Lee, Olivier Donnars, Se-Ho Park, Andrew Beavis, Yasuhiko Koezuka, and Albert Bendelac
J Immunol 1999 163: 4647-4650. [Abstract] [Full Text] [PDF]

Cutting Edge: KAP10, a Novel Transmembrane Adapter Protein Genetically Linked to DAP12 but with Unique Signaling Properties: Chiwen Chang, Jes Dietrich, Ailsa G. Harpur, Jonathan A. Lindquist, Anja Haude, Y. W. Loke, Ashley King, Marco Colonna, John Trowsdale, and Michael J. Wilson
J Immunol 1999 163: 4651-4654. [Abstract] [Full Text] [PDF]

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Mitochondria Connects the Antigen Receptor to Effector Caspases During B Cell Receptor-Induced Apoptosis in Normal Human B Cells: Marion Berard, Paul Mondière, Montserrat Casamayor-Pallejà, Ana Hennino, Chantal Bella, and Thierry Defrance
J Immunol 1999 163: 4655-4662. [Abstract] [Full Text] [PDF]

Paired Stat6 C-Terminal Transcription Activation Domains Required Both for Inhibition of an IFN-Responsive Promoter and Trans-Activation: Shreevrat Goenka, Jeehee Youn, Linda M. Dzurek, Ulrike Schindler, Li-yuan Yu-Lee, and Mark Boothby
J Immunol 1999 163: 4663-4672. [Abstract] [Full Text] [PDF]

T_H Cells Primed During Influenza Virus Infection Provide Help for Qualitatively Distinct Antibody Responses to Subsequent Immunization: Dana Marshall, Robert Sealy, Mark Sangster, and Christopher Coleclough
J Immunol 1999 163: 4673-4682. [Abstract] [Full Text] [PDF]

Granzyme B-Induced Loss of Mitochondrial Inner Membrane Potential ( ${Delta}$ ${Psi}$ _m) and Cytochrome c Release Are Caspase Independent: Jeffrey A. Heibein, Michele Barry, Bruce Motyka, and R. Chris Bleackley
J Immunol 1999 163: 4683-4693. [Abstract] [Full Text] [PDF]

Natural Killing of Xenogeneic Cells Mediated by the Mouse Ly-49D Receptor: Mary C. Nakamura, Christian Naper, Eréne C. Niemi, Steven C. Spusta, Bent Rolstad, Geoffrey W. Butcher, William E. Seaman, and James C. Ryan
J Immunol 1999 163: 4694-4700. [Abstract] [Full Text] [PDF]

Antigen Presentation Determines the Fate of the T Memory Response In Vivo After Sublethal Gamma-Irradiation: Joan M. G. Sechler, Susan A. Hansal, Diane I. Morris, Hugh I. McFarland, and Amy S. Rosenberg
J Immunol 1999 163: 4701-4706. [Abstract] [Full Text] [PDF]

Switching to IgG3, IgG2b, and IgA Is Division Linked and Independent, Revealing a Stochastic Framework for Describing Differentiation: Elissa K. Deenick, Jhagvaral Hasbold, and Philip D. Hodgkin
J Immunol 1999 163: 4707-4714. [Abstract] [Full Text] [PDF]

Macrophage Inflammatory Protein-3ß Enhances IL-10 Production by Activated Human Peripheral Blood Monocytes and T Cells: Heather D. Byrnes, Heather Kaminski, Asra Mirza, Gregory Deno, Daniel Lundell, and Jay S. Fine
J Immunol 1999 163: 4715-4720. [Abstract] [Full Text] [PDF]

In Vivo Priming by DNA Injection Occurs Predominantly by Antigen Transfer: Maripat Corr, Amila von Damm, Delphine J. Lee, and Helen Tighe
J Immunol 1999 163: 4721-4727. [Abstract] [Full Text] [PDF]

Normal Induction of Oral Tolerance in the Absence of a Functional IL-12-Dependent IFN- ${gamma}$ Signaling Pathway: Allan McI. Mowat, Margaret Steel, Andrew J. Leishman, and Paul Garside
J Immunol 1999 163: 4728-4736. [Abstract] [Full Text] [PDF]

Protein Kinase C Inhibits CD95 (Fas/APO-1)-Mediated Apoptosis by at Least Two Different Mechanisms in Jurkat T Cells: Carmen Ruiz-Ruiz, Gema Robledo, Jovita Font, Manuel Izquierdo, and Abelardo López-Rivas
J Immunol 1999 163: 4737-4746. [Abstract] [Full Text] [PDF]

Age-Associated Rapid and Stat6-Independent IL-4 Production by NK1^-CD4⁺8^- Thymus T Lymphocytes: Yi-Ting Chen, Fen-Ling Chen, and John T. Kung
J Immunol 1999 163: 4747-4753. [Abstract] [Full Text] [PDF]

Presence of CpG DNA and the Local Cytokine Milieu Determine the Efficacy of Suppressive DNA Vaccination in Experimental Autoimmune Encephalomyelitis: Anna Lobell, Robert Weissert, Sana Eltayeb, Cecilia Svanholm, Tomas Olsson, and Hans Wigzell
J Immunol 1999 163: 4754-4762. [Abstract] [Full Text] [PDF]

p38 Mitogen-Activated Protein Kinase Regulates Human T Cell IL-5 Synthesis: Akio Mori, Osamu Kaminuma, Keiji Miyazawa, Koji Ogawa, Hirokazu Okudaira, and Kazuo Akiyama
J Immunol 1999 163: 4763-4771. [Abstract] [Full Text] [PDF]

Selective Up-Regulation of Phosphatidylinositol 3'-Kinase Activity in Th2 Cells Inhibits Caspase-8 Cleavage at the Death-Inducing Complex: A Mechanism for Th2 Resistance from Fas-Mediated Apoptosis: Arun S. Varadhachary, Marcus E. Peter, Somia N. Perdow, Peter H. Krammer, and Padmini Salgame
J Immunol 1999 163: 4772-4779. [Abstract] [Full Text] [PDF]

Visualization, Fate, and Pathogenicity of Antigen-Specific CD8⁺ T Cells in the Graft-Versus-Host Reaction: Xue-Zhong Yu, Sasha Bidwell, Paul J. Martin, and Claudio Anasetti
J Immunol 1999 163: 4780-4787. [Abstract] [Full Text] [PDF]

Emergence of T, B, and Myeloid Lineage-Committed as well as Multipotent Hemopoietic Progenitors in the Aorta-Gonad- Mesonephros Region of Day 10 Fetuses of the Mouse: Koichiro Ohmura, Hiroshi Kawamoto, Shinji Fujimoto, Shoichi Ozaki, Kazuwa Nakao, and Yoshimoto Katsura
J Immunol 1999 163: 4788-4795. [Abstract] [Full Text] [PDF]

Peripheral CD4⁺ T Cell Maturation Recognized by Increased Expression of Thy-1/CD90 Bearing the 6C10 Carbohydrate Epitope: Ming Gui, David L. Wiest, Jin Li, Dietmar Kappes, Richard R. Hardy, and Kyoko Hayakawa
J Immunol 1999 163: 4796-4804. [Abstract] [Full Text] [PDF]

CD40 Ligand Blockade Induces CD4⁺ T Cell Tolerance and Linked Suppression: Karen Honey, Stephen P. Cobbold, and Herman Waldmann
J Immunol 1999 163: 4805-4810. [Abstract] [Full Text] [PDF]

Differential Requirements for CD4 in TCR-Ligand Interactions: Karine Vidal, Claude Daniel, Mark Hill, Dan R. Littman, and Paul M. Allen
J Immunol 1999 163: 4811-4818. [Abstract] [Full Text] [PDF]

Mutual Regulation Between B7-1 (CD80) Expressed on T Cells and IL-4: A. Nicola Schweitzer and Arlene H. Sharpe
J Immunol 1999 163: 4819-4825. [Abstract] [Full Text] [PDF]

Defective CD8⁺ T Cell Activation and Cytolytic Function in the Absence of LFA-1 Cannot Be Restored by Increased TCR Signaling: Peter Shier, Karen Ngo, and Wai-Ping Fung-Leung
J Immunol 1999 163: 4826-4832. [Abstract] [Full Text] [PDF]

Analysis of 4-1BB Ligand (4-1BBL)-Deficient Mice and of Mice Lacking Both 4-1BBL and CD28 Reveals a Role for 4-1BBL in Skin Allograft Rejection and in the Cytotoxic T Cell Response to Influenza Virus: Mark A. DeBenedette, Tao Wen, Martin F. Bachmann, Pamela S. Ohashi, Brian H. Barber, Kim L. Stocking, Jacques J. Peschon, and Tania H. Watts
J Immunol 1999 163: 4833-4841. [Abstract] [Full Text] [PDF]

The Th1/Th2 Nature of Concurrent Immune Responses to Unrelated Antigens Can Be Independent: Nahed Ismail and Peter A. Bretscher
J Immunol 1999 163: 4842-4850. [Abstract] [Full Text] [PDF]

Thymocyte Antigens Do Not Induce Tolerance in the CD4⁺ T Cell Compartment: Kanchan G. Jhaver, Phillip Chandler, Elizabeth Simpson, and Andrew L. Mellor
J Immunol 1999 163: 4851-4858. [Abstract] [Full Text] [PDF]

4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses: Joyce T. Tan, Jason K. Whitmire, Rafi Ahmed, Thomas C. Pearson, and Christian P. Larsen
J Immunol 1999 163: 4859-4868. [Abstract] [Full Text] [PDF]

CD34⁺ Cell-Derived CD14⁺ Precursor Cells Develop into Langerhans Cells in a TGF-ß1-Dependent Manner: Silvia Jaksits, Ernst Kriehuber, Anne Sophie Charbonnier, Klemens Rappersberger, Georg Stingl, and Dieter Maurer
J Immunol 1999 163: 4869-4877. [Abstract] [Full Text] [PDF]

T Cell Infiltration into Class II MHC-Disparate Allografts and Acute Rejection Is Dependent on the IFN- ${gamma}$ -Induced Chemokine Mig: Shoji Koga, Michael B. Auerbach, Tara M. Engeman, Andrew C. Novick, Hiroshi Toma, and Robert L. Fairchild
J Immunol 1999 163: 4878-4885. [Abstract] [Full Text] [PDF]

A "Stealth Effect": Adenocarcinoma Cells Engineered to Express TRAIL Elude Tumor-Specific and Allogeneic T Cell Reactions: Mirella Giovarelli, Piero Musiani, Gianni Garotta, Reinhard Ebner, Emma Di Carlo, Yunsoo Kim, Paola Cappello, Laura Rigamonti, Paola Bernabei, Francesco Novelli, Andrea Modesti, Anna Coletti, Ann Kim Ferrie, Pier-Luigi Lollini, Steve Ruben, Theodora Salcedo, and Guido Forni
J Immunol 1999 163: 4886-4893. [Abstract] [Full Text] [PDF]

Influence of Lymphocytes on the Presence and Organization of Dendritic Cell Subsets in the Spleen: Mary T. Crowley, Christina R. Reilly, and David Lo
J Immunol 1999 163: 4894-4900. [Abstract] [Full Text] [PDF]

A Novel Role for H-Ras in the Regulation of Very Late Antigen-4 Integrin and VCAM-1 Via c-Myc-Dependent and -Independent Mechanisms: Zhao-Jun Liu, Yoshiya Tanaka, Hiroko Fujimoto, Shinichiro Mine, Akio Morinobu, Hideo Yagita, Ko Okumura, Isao Oishi, Jun Udagawa, Hirohei Yamamura, and Yasuhiro Minami
J Immunol 1999 163: 4901-4908. [Abstract] [Full Text] [PDF]

In Vivo Evidence That Caspase-3 Is Required for Fas-Mediated Apoptosis of Hepatocytes: Minna Woo, Anne Hakem, Andrew J. Elia, Razqallah Hakem, Gordon S. Duncan, Bruce J. Patterson, and Tak W. Mak
J Immunol 1999 163: 4909-4916. [Abstract] [Full Text] [PDF]

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

CD44-Deficient Mice Develop Normally with Changes in Subpopulations and Recirculation of Lymphocyte Subsets: Ursula Protin, Tamas Schweighoffer, Wolfram Jochum, and Frank Hilberg
J Immunol 1999 163: 4917-4923. [Abstract] [Full Text] [PDF]

Distinct Mechanisms Target Stress and Extracellular Signal-Activated Kinase 1 and Jun N-Terminal Kinase During Infection of Macrophages with Salmonella: Katarzyna J. Procyk, Maria Rita Rippo, Roberto Testi, Fred Hoffmann, Peter J. Parker, and Manuela Baccarini
J Immunol 1999 163: 4924-4930. [Abstract] [Full Text] [PDF]

Cloning and Characterization of a Novel Activating Ly49 Closely Related to Ly49A ^,2 ^,3: Andrew P. Makrigiannis, Pierre Gosselin, Llewellyn H. Mason, Lynn S. Taylor, Daniel W. McVicar, John R. Ortaldo, and Stephen K. Anderson
J Immunol 1999 163: 4931-4938. [Abstract] [Full Text] [PDF]

Quantitative Alleles of CR1: Coding Sequence Analysis and Comparison of Haplotypes in Two Ethnic Groups: Lianbin Xiang, Jennifer R. Rundles, Derrick R. Hamilton, and James G. Wilson
J Immunol 1999 163: 4939-4945. [Abstract] [Full Text] [PDF]

Systematic Mutagenesis of TCR Complementarity-Determining Region 3 Residues: A Single Conservative Substitution Dramatically Improves Response to Both Multiple HLA-DR Alleles and Peptide Variants: James V. Brawley and Patrick Concannon
J Immunol 1999 163: 4946-4952. [Abstract] [Full Text] [PDF]

Molecular Defects in Variant Forms of Mannose-Binding Protein Associated with Immunodeficiency: Russell Wallis and Jason Y. T. Cheng
J Immunol 1999 163: 4953-4959. [Abstract] [Full Text] [PDF]

Immune-Associated Nucleotide-1 (IAN-1) Is a Thymic Selection Marker and Defines a Novel Gene Family Conserved in Plants: Ghislaine M. C. Poirier, Graham Anderson, Arne Huvar, Pamela C. Wagaman, John Shuttleworth, Eric Jenkinson, Michael R. Jackson, Per A. Peterson, and Mark G. Erlander
J Immunol 1999 163: 4960-4969. [Abstract] [Full Text] [PDF]

HOST DEFENSE:

An Essential Role for Antibody in Neutrophil and Eosinophil Recruitment to the Cornea: B Cell-Deficient (µMT) Mice Fail to Develop Th2-Dependent, Helminth-Mediated Keratitis: Laurie R. Hall, Jonathan H. Lass, Eugenia Diaconu, Ellen R. Strine, and Eric Pearlman
J Immunol 1999 163: 4970-4975. [Abstract] [Full Text] [PDF]

Nitric Oxide and the Th2 Response Combine to Prevent Severe Hepatic Damage During Schistosoma mansoni Infection: L. Rosa Brunet, M. Beall, D. W. Dunne, and E. J. Pearce
J Immunol 1999 163: 4976-4984. [Abstract] [Full Text] [PDF]

Neutralization of Endogenous Granulocyte-Macrophage Colony-Stimulating Factor Subverts the Protective Immune Response to Histoplasma capsulatum: George S. Deepe, Jr., Reta Gibbons, and Erin Woodward
J Immunol 1999 163: 4985-4993. [Abstract] [Full Text] [PDF]

A Cyclophilin B Gene Encodes Antigenic Epitopes Recognized by HLA-A24-Restricted and Tumor-Specific CTLs: Shinya Gomi, Masanobu Nakao, Fumihiko Niiya, Yutaka Imamura, Kouichiro Kawano, Shinya Nishizaka, Akihiko Hayashi, Yuji Sobao, Kotaro Oizumi, and Kyogo Itoh
J Immunol 1999 163: 4994-5004. [Abstract] [Full Text] [PDF]

Nematode Infection Enhances Survival of Activated T Cells by Modulating Accessory Cell Function: Robert S. Liwski and Timothy D. G. Lee
J Immunol 1999 163: 5005-5012. [Abstract] [Full Text] [PDF]

Neutrophil Dysfunctions, IL-8, and Soluble L-Selectin Plasma Levels in Rapidly Progressive Versus Adult and Localized Juvenile Periodontitis: Variations According to Disease Severity and Microbial Flora: Jean Gainet, Pham M. C. Dang, Sylvie Chollet-Martin, Monique Brion, Michel Sixou, Jacques Hakim, Marie-Anne Gougerot-Pocidalo, and Carole Elbim
J Immunol 1999 163: 5013-5019. [Abstract] [Full Text] [PDF]

T Cell-Derived IL-10 Promotes Lung Cancer Growth by Suppressing Both T Cell and APC Function: Sherven Sharma, Marina Stolina, Ying Lin, Brian Gardner, Patrice W. Miller, Mitchell Kronenberg, and Steven M. Dubinett
J Immunol 1999 163: 5020-5028. [Abstract] [Full Text] [PDF]

INFLAMMATION:

Relative Contribution of LFA-1 and Mac-1 to Neutrophil Adhesion and Migration: Zhi-Ming Ding, Julia E. Babensee, Scott I. Simon, Huifang Lu, Jerry L. Perrard, Daniel C. Bullard, Xiao Y. Dai, Shannon K. Bromley, Michael L. Dustin, Mark L. Entman, C. Wayne Smith, and Christie M. Ballantyne
J Immunol 1999 163: 5029-5038. [Abstract] [Full Text] [PDF]

A Novel LPS-Inducible C-Type Lectin Is a Transcriptional Target of NF-IL6 in Macrophages: Makoto Matsumoto, Takashi Tanaka, Tsuneyasu Kaisho, Hideki Sanjo, Neal G. Copeland, Debra J. Gilbert, Nancy A. Jenkins, and Shizuo Akira
J Immunol 1999 163: 5039-5048. [Abstract] [Full Text] [PDF]

IL-1 ${alpha}$ ß Blockade Prevents Cartilage and Bone Destruction in Murine Type II Collagen-Induced Arthritis, Whereas TNF- ${alpha}$ Blockade Only Ameliorates Joint Inflammation: Leo A. B. Joosten, Monique M. A. Helsen, Tore Saxne, Fons A. J. van de Loo, and Wim B. van den Berg
J Immunol 1999 163: 5049-5055. [Abstract] [Full Text] [PDF]

C1q and C4b Bind Simultaneously to CR1 and Additively Support Erythrocyte Adhesion: Sander W. Tas, Lloyd B. Klickstein, Sergei F. Barbashov, and Anne Nicholson-Weller
J Immunol 1999 163: 5056-5063. [Abstract] [Full Text] [PDF]

Proteinase-Activated Receptor-2-Activating Peptides Induce Leukocyte Rolling, Adhesion, and Extravasation In Vivo: Nathalie Vergnolle
J Immunol 1999 163: 5064-5069. [Abstract] [Full Text] [PDF]

L-Selectin Ligands Expressed by Human Leukocytes Are HECA-452 Antibody-Defined Carbohydrate Epitopes Preferentially Displayed by P-Selectin Glycoprotein Ligand-1: LiLi Tu, Patricia G. Murphy, Xuan Li, and Thomas F. Tedder
J Immunol 1999 163: 5070-5078. [Abstract] [Full Text] [PDF]

Src-Regulated Extracellular Signal-Related Kinase and Syk-Regulated c-Jun N-Terminal Kinase Pathways Act in Conjunction to Induce IL-1 Synthesis in Response to Microtubule Disruption in HL60 Cells: Béatrice Cambien, Marie-Ange Millet, Heidy Schmid-Antomarchi, Nicole Brossette, Bernard Rossi, and Annie Schmid-Alliana
J Immunol 1999 163: 5079-5085. [Abstract] [Full Text] [PDF]

Tissue Specificity of E- and P-Selectin Ligands in Th1-Mediated Chronic Inflammation: Alvina Chu, Kenneth Hong, Ellen L. Berg, and Rolf O. Ehrhardt
J Immunol 1999 163: 5086-5093. [Abstract] [Full Text] [PDF]

Role of IL-6 in the Pleurisy and Lung Injury Caused by Carrageenan: Salvatore Cuzzocrea, Lidia Sautebin, Giovambattista De Sarro, Giuseppina Costantino, Laura Rombolà, Emanuela Mazzon, Armando Ialenti, Angela De Sarro, Gennaro Ciliberto, Massimo Di Rosa, Achille P. Caputi, and Christoph Thiemermann
J Immunol 1999 163: 5094-5104. [Abstract] [Full Text] [PDF]

Recombinant Human (rh)IL-4-Mediated Apoptosis and Recombinant Human IL-6-Mediated Protection of Recombinant Human Stem Cell Factor-Dependent Human Mast Cells Derived from Cord Blood Mononuclear Cell Progenitors: Carole A. Oskeritzian, Zhiliang Wang, Jarema P. Kochan, Margaret Grimes, Zhongmin Du, Hyeun-Wook Chang, Steven Grant, and Lawrence B. Schwartz
J Immunol 1999 163: 5105-5115. [Abstract] [Full Text] [PDF]

Preferential Role for NF- ${kappa}$ B/Rel Signaling in the Type 1 But Not Type 2 T Cell-Dependent Immune Response In Vivo: Mark A. Aronica, Ana L. Mora, Daphne B. Mitchell, Patricia W. Finn, Joyce E. Johnson, James R. Sheller, and Mark R. Boothby
J Immunol 1999 163: 5116-5124. [Abstract] [Full Text] [PDF]

CLINICAL IMMUNOLOGY:

Granulocyte-Colony Stimulating Factor Treatment of Lupus Autoimmune Disease in MRL-lpr/lpr Mice: Flora Zavala, Annie Masson, Karine Hadaya, Sophie Ezine, Elke Schneider, Olivier Babin, and Jean-François Bach
J Immunol 1999 163: 5125-5132. [Abstract] [Full Text] [PDF]

B Cell Repertoire Diversity and Clonal Expansion in Multiple Sclerosis Brain Lesions: Sergio E. Baranzini, Matthew C. Jeong, Catalin Butunoi, Ronald S. Murray, Claude C. A. Bernard, and Jorge R. Oksenberg
J Immunol 1999 163: 5133-5144. [Abstract] [Full Text] [PDF]

Photochemical Treatment with S-59 Psoralen and Ultraviolet A Light to Control the Fate of Naive or Primed T Lymphocytes In Vivo After Allogeneic Bone Marrow Transplantation: Robert L. Truitt, Bryon D. Johnson, Carrie Hanke, Sohel Talib, and John E. Hearst
J Immunol 1999 163: 5145-5156. [Abstract] [Full Text] [PDF]

Induction of Experimental Autoimmune Graves’ Disease in BALB/c Mice: Shashi Kaithamana, Jilao Fan, Yutaka Osuga, Shan-Guang Liang, and Bellur S. Prabhakar
J Immunol 1999 163: 5157-5164. [Abstract] [Full Text] [PDF]