CUTTING EDGE:

Cutting Edge: Paradigm Revisited: Antibody Provides Resistance to Listeria Infection

Brian T. Edelson, Pascale Cossart, and Emil R. Unanue
J Immunol 1999 163: 4087-4090. [Abstract] [Full Text] [PDF]  

Cutting Edge: NKT Cell Development Is Selectively Impaired in Fyn- Deficient Mice

Gérard Eberl, Bente Lowin-Kropf, and H. Robson MacDonald
J Immunol 1999 163: 4091-4094. [Abstract] [Full Text] [PDF]  

Cutting Edge: Bacterial DNA and LPS Act in Synergy in Inducing Nitric Oxide Production in RAW 264.7 Macrophages

Jian Jun Gao, Eleanor G. Zuvanich, Qiao Xue, David L. Horn, Richard Silverstein, and David C. Morrison
J Immunol 1999 163: 4095-4099. [Abstract] [Full Text] [PDF]  

Cutting Edge: TCRß⁺ CD8⁺ T Cells Are Found in Intestinal Intraepithelial Lymphocytes of Mice That Lack Classical MHC Class I Molecules

Laurent Gapin, Hilde Cheroutre, and Mitchell Kronenberg
J Immunol 1999 163: 4100-4104. [Abstract] [Full Text] [PDF]  

Cutting Edge: A Dominant Negative Form of TNF- Converting Enzyme Inhibits ProTNF and TNFRII Secretion

Kimberly A. Solomon, Nancy Pesti, Guoxin Wu, and Robert C. Newton
J Immunol 1999 163: 4105-4108. [Abstract] [Full Text] [PDF]  

Cutting Edge: Differentiation of Antitumor CTL In Vivo Requires Host Expression of Stat1

Francesca Fallarino and Thomas F. Gajewski
J Immunol 1999 163: 4109-4113. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

A Caspase-Independent Pathway of MHC Class II Antigen-Mediated Apoptosis of Human B Lymphocytes

Bernard Drénou, Vincent Blancheteau, David H. Burgess, Renée Fauchet, Dominique J. Charron, and Nuala A. Mooney
J Immunol 1999 163: 4115-4124. [Abstract] [Full Text] [PDF]  

Induction and Visualization of Mucosal Memory CD8 T Cells Following Systemic Virus Infection

Sung-Kwon Kim, Kimberly S. Schluns, and Leo Lefrançois
J Immunol 1999 163: 4125-4132. [Abstract] [Full Text] [PDF]  

Cell Surface Expression of the Endoplasmic Reticular Heat Shock Protein gp96 Is Phylogenetically Conserved

Jacques Robert, Antoine Ménoret, and Nicholas Cohen
J Immunol 1999 163: 4133-4139. [Abstract] [Full Text] [PDF]  

Adenosine Inhibits Macrophage Colony-Stimulating Factor-Dependent Proliferation of Macrophages Through the Induction of p27^kip-1 Expression

Jordi Xaus, Annabel F. Valledor, Marina Cardó, Laura Marquès, Jorge Beleta, José M. Palacios, and Antonio Celada
J Immunol 1999 163: 4140-4149. [Abstract] [Full Text] [PDF]  

Expression, Regulation, and Function of B Cell-Expressed CD154 in Germinal Centers

Amrie C. Grammer, Richard D. McFarland, Jonathan Heaney, Bonnie F. Darnell, and Peter E. Lipsky
J Immunol 1999 163: 4150-4159. [Abstract] [Full Text] [PDF]  

Cytokine Requirements for Production of a Novel Anti-CD8-Resistant CTL Population

Esi S. N. Lamousé-Smith, David S. Dougall, and Susan A. McCarthy
J Immunol 1999 163: 4160-4167. [Abstract] [Full Text] [PDF]  

Estrogen Receptor Is Necessary in Thymic Development and Estradiol-Induced Thymic Alterations

J. Erin Staples, Thomas A. Gasiewicz, Nancy C. Fiore, Dennis B. Lubahn, Kenneth S. Korach, and Allen E. Silverstone
J Immunol 1999 163: 4168-4174. [Abstract] [Full Text] [PDF]  

Integrating Signals from IFN- and IL-4 by B Cells: Positive and Negative Effects on CD40 Ligand-Induced Proliferation, Survival, and Division-Linked Isotype Switching to IgG1, IgE, and IgG2a

Jhagvaral Hasbold, Jonathan Sui-Yin Hong, Marilyn R. Kehry, and Philip D. Hodgkin
J Immunol 1999 163: 4175-4181. [Abstract] [Full Text] [PDF]  

Nitric Oxide Suppresses Human T Lymphocyte Proliferation Through IFN--Dependent and IFN--Independent Induction of Apoptosis

Alessandra Allione, Paola Bernabei, Marita Bosticardo, Silvia Ariotti, Guido Forni, and Francesco Novelli
J Immunol 1999 163: 4182-4191. [Abstract] [Full Text] [PDF]  

Genetic Evidence for Lyn as a Negative Regulator of IL-4 Signaling

Michelle L. Janas, Philip Hodgkin, Margaret Hibbs, and David Tarlinton
J Immunol 1999 163: 4192-4198. [Abstract] [Full Text] [PDF]  

Characterization of RNA Binding Proteins Associated with CD40 Ligand (CD154) mRNA Turnover in Human T Lymphocytes

W. F. C. Rigby, M. G. Waugh, and B. J. Hamilton
J Immunol 1999 163: 4199-4206. [Abstract] [Full Text] [PDF]  

NK Cell Triggering by the Human Costimulatory Molecules CD80 and CD86

Julia L. Wilson, Jehad Charo, Alfonso Martín-Fontecha, Paolo Dellabona, Giulia Casorati, Benedict J. Chambers, Rolf Kiessling, Maria-Teresa Bejarano, and Hans-Gustaf Ljunggren
J Immunol 1999 163: 4207-4212. [Abstract] [Full Text] [PDF]  

VIP and PACAP Differentially Regulate the Costimulatory Activity of Resting and Activated Macrophages Through the Modulation of B7.1 and B7.2 Expression

Mario Delgado, Wei Sun, Javier Leceta, and Doina Ganea
J Immunol 1999 163: 4213-4223. [Abstract] [Full Text] [PDF]  

Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis

A. K. Johnsen, D. J. Templeton, M.-S. Sy, and C. V. Harding
J Immunol 1999 163: 4224-4231. [Abstract] [Full Text] [PDF]  

The Self-Directed T Cell Repertoire Against Mouse Lysozyme Reflects the Influence of the Hierarchy of Its Own Determinants and Can Be Engaged by a Foreign Lysozyme

Kamal D. Moudgil, Scott Southwood, Akio Ametani, Kasey Kim, Alessandro Sette, and Eli E. Sercarz
J Immunol 1999 163: 4232-4237. [Abstract] [Full Text] [PDF]  

CD2 and CD3 Associate Independently with CD5 and Differentially Regulate Signaling Through CD5 in Jurkat T Cells

Alexandre M. Carmo, Mónica A. A. Castro, and Fernando A. Arosa
J Immunol 1999 163: 4238-4245. [Abstract] [Full Text] [PDF]  

Role of IL-12 in the Induction and Potentiation of IFN- in Response to Bacillus Calmette-Guérin

Michael A. O’Donnell, Yi Luo, Xiaohong Chen, Akos Szilvasi, Sharon E. Hunter, and Steven K. Clinton
J Immunol 1999 163: 4246-4252. [Abstract] [Full Text] [PDF]  

LFA-1 to LFA-1 Signals Involve -Associated Protein-70 (ZAP-70) Tyrosine Kinase: Relevance for Invasion and Migration of a T Cell Hybridoma

Ron D. M. Soede, Mariëtte H. E. Driessens, Lisette Ruuls-Van Stalle, Paula E. M. Van Hulten, Arjen Brink, and Ed Roos
J Immunol 1999 163: 4253-4261. [Abstract] [Full Text] [PDF]  

Failure of Rearranged TCR Transgenes to Prevent Age-Associated Thymic Involution

H. Daniel Lacorazza, Jose A. Guevara Patiño, Marc E. Weksler, and Dorel Radu
J Immunol 1999 163: 4262-4268. [Abstract] [Full Text] [PDF]  

Systemic Expression of Rat Soluble Retinal Antigen Induces Resistance to Experimental Autoimmune Uveoretinitis

Scott W. McPherson, Josh P. Roberts, and Dale S. Gregerson
J Immunol 1999 163: 4269-4276. [Abstract] [Full Text] [PDF]  

A Soluble Factor Produced by Lamina Propria Mononuclear Cells Is Required for TNF- Enhancement of IFN- Production by T Cells

John L. Prehn, Carol J. Landers, and Stephan R. Targan
J Immunol 1999 163: 4277-4283. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Derived IL-12 Promotes B Cell Induction of Th2 Differentiation: A Feedback Regulation of Th1 Development

Jane Skok, Johanne Poudrier, and David Gray
J Immunol 1999 163: 4284-4291. [Abstract] [Full Text] [PDF]  

Inhibition of CD28 Expression by Oligonucleotide Decoys to the Regulatory Element in Exon 1 of the CD28 Gene

Robert C. Tam, Catherine J. Lin, Charmaine Lim, Bharati Pai, and Vesna Stoisavljevic
J Immunol 1999 163: 4292-4299. [Abstract] [Full Text] [PDF]  

Naive and Memory T Lymphocytes Migrate in Comparable Numbers Through Normal Rat Liver: Activated T Cells Accumulate in the Periportal Field

Birgit Luettig, Lars Pape, Ulrike Bode, Eric B. Bell, Sheila M. Sparshott, Siegfried Wagner, and Jürgen Westermann
J Immunol 1999 163: 4300-4307. [Abstract] [Full Text] [PDF]  

Cerebral Endothelial Cells Release TNF- After Stimulation with Cell Walls of Streptococcus pneumoniae and Regulate Inducible Nitric Oxide Synthase and ICAM-1 Expression Via Autocrine Loops

Dorette Freyer, Rahel Manz, Andreas Ziegenhorn, Markus Weih, Klemens Angstwurm, Wolf-Dietrich Döcke, Andreas Meisel, Ralf R. Schumann, Gilbert Schönfelder, Ulrich Dirnagl, and Joerg R. Weber
J Immunol 1999 163: 4308-4314. [Abstract] [Full Text] [PDF]  

Contrasting the In Situ Behavior of a Memory B Cell Clone During Primary and Secondary Immune Responses

Kalpit A. Vora, Kathleen Tumas-Brundage, and Tim Manser
J Immunol 1999 163: 4315-4327. [Abstract] [Full Text] [PDF]  

Ligation of CD28 In Vivo Induces CD40 Ligand Expression and Promotes B Cell Survival

Deling Yin, Liying Zhang, Ruoxiang Wang, Laszlo Radvanyi, Christian Haudenschild, Qiding Fang, Marilyn R. Kehry, and Yufang Shi
J Immunol 1999 163: 4328-4334. [Abstract] [Full Text] [PDF]  

Comparing the Relative Role of Perforin/Granzyme Versus Fas/Fas Ligand Cytotoxic Pathways in CD8⁺ T Cell-Mediated Insulin-Dependent Diabetes Mellitus

Huub T. C. Kreuwel, David J. Morgan, Troy Krahl, Alice Ko, Nora Sarvetnick, and Linda A. Sherman
J Immunol 1999 163: 4335-4341. [Abstract] [Full Text] [PDF]  

Specificity of CTL Interactions with Peptide-MHC Class I Tetrameric Complexes Is Temperature Dependent

Joseph A. Whelan, P. Rod Dunbar, David A. Price, Marco A. Purbhoo, Franziska Lechner, Graham S. Ogg, Gillian Griffiths, Rodney E. Phillips, Vincenzo Cerundolo, and Andrew K. Sewell
J Immunol 1999 163: 4342-4348. [Abstract] [Full Text] [PDF]  

Role of IL-12 in Intrathymic Negative Selection

Björn R. Lúdvíksson, Rolf O. Ehrhardt, and Warren Strober
J Immunol 1999 163: 4349-4359. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Monoclonal Antibodies That Distinguish Between Two Related Digitalis Glycosides, Ouabain and Digoxin

Behnaz Parhami-Seren, Charles Bell, Michael N. Margolies, and Garner T. Haupert, Jr.
J Immunol 1999 163: 4360-4366. [Abstract] [Full Text] [PDF]  

Amplitude and Frequency Modulation of Metabolic Signals in Leukocytes: Synergistic Role of IFN- in IL-6- and IL-2-Mediated Cell Activation

Yoshiyuki Adachi, Andrei L. Kindzelskii, Naohito Ohno, Toshiro Yadomae, and Howard R. Petty
J Immunol 1999 163: 4367-4374. [Abstract] [Full Text] [PDF]  

Transcriptional Regulation of the Ig Gene by Promoter-Proximal Pausing of RNA Polymerase II

Eva E. Raschke, Thomas Albert, and Dirk Eick
J Immunol 1999 163: 4375-4382. [Abstract] [Full Text] [PDF]  

Functional Synergism of STAT6 with Either NF-B or PU.1 to Mediate IL-4-Induced Activation of IgE Germline Gene Transcription

Adrian M. Stütz and Maximilian Woisetschläger
J Immunol 1999 163: 4383-4391. [Abstract] [Full Text] [PDF]  

A Recurrent Breakpoint in the Most Common Deletion of the Ig Heavy Chain Locus (del A1-GP-G2-G4-E )

Alfredo Brusco, Silvia Saviozzi, Fernanda Cinque, Andrea Bottaro, and Mario DeMarchi
J Immunol 1999 163: 4392-4398. [Abstract] [Full Text] [PDF]  

The Human Antibody Response to Porcine Xenoantigens Is Encoded by IGHV3-11 and IGHV3-74 IgV_H Germline Progenitors

Mary Kearns-Jonker, Joyce Swensson, Cristina Ghiuzeli, Wilson Chu, Yuka Osame, Vaughn Starnes, and Donald V. Cramer
J Immunol 1999 163: 4399-4412. [Abstract] [Full Text] [PDF]  

Thermolabile H-2K^b Molecules Expressed by Transporter Associated with Antigen Processing-Deficient RMA-S Cells Are Occupied by Low-Affinity Peptides

A. Dharshan De Silva, Alina Boesteanu, Rui Song, Nancy Nagy, Edward Harhaj, Clifford V. Harding, and Sebastian Joyce
J Immunol 1999 163: 4413-4420. [Abstract] [Full Text] [PDF]  

An Antibody-Avidin Fusion Protein Specific for the Transferrin Receptor Serves as a Delivery Vehicle for Effective Brain Targeting: Initial Applications in Anti-HIV Antisense Drug Delivery to the Brain

Manuel L. Penichet, Young-Sook Kang, William M. Pardridge, Sherie L. Morrison, and Seung-Uon Shin
J Immunol 1999 163: 4421-4426. [Abstract] [Full Text] [PDF]  

An Extensive Region of an MHC Class I 2 Domain Loop Influences Interaction with the Assembly Complex

Yik Y. L. Yu, Heth R. Turnquist, Nancy B. Myers, Ganesaratnam K. Balendiran, Ted H. Hansen, and Joyce C. Solheim
J Immunol 1999 163: 4427-4433. [Abstract] [Full Text] [PDF]  

Binding of Longer Peptides to the H-2K^b Heterodimer Is Restricted to Peptides Extended at Their C Terminus: Refinement of the Inherent MHC Class I Peptide Binding Criteria

Heidi Hörig, Aideen C. M. Young, Nicholas J. Papadopoulos, Teresa P. DiLorenzo, and Stanley G. Nathenson
J Immunol 1999 163: 4434-4441. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

The Epithelial Cell Response to Rotavirus Infection

Ellen E. Rollo, K. Prasanna Kumar, Nancy C. Reich, Jean Cohen, Juana Angel, Harry B. Greenberg, Riten Sheth, Joseph Anderson, Brian Oh, Scott J. Hempson, Erich R. Mackow, and Robert D. Shaw
J Immunol 1999 163: 4442-4452. [Abstract] [Full Text] [PDF]  

The NF-B Family Member RelB Is Required for Innate and Adaptive Immunity to Toxoplasma gondii

Jorge Caamaño, James Alexander, Linden Craig, Rodrigo Bravo, and Christopher A. Hunter
J Immunol 1999 163: 4453-4461. [Abstract] [Full Text] [PDF]  

Tumor Regression After Adoptive Transfer of Effector T Cells Is Independent of Perforin or Fas Ligand (APO-1L/CD95L)

Hauke Winter, Hong-Ming Hu, Walter J. Urba, and Bernard A. Fox
J Immunol 1999 163: 4462-4472. [Abstract] [Full Text] [PDF]  

Up-Regulation of NK Cytotoxic Activity Via IL-15 Induction by Different Viruses: A Comparative Study

Lama M. Fawaz, Ehsan Sharif-Askari, and José Menezes
J Immunol 1999 163: 4473-4480. [Abstract] [Full Text] [PDF]  

Protective Immunity Using Recombinant Human IL-12 and Alum as Adjuvants in a Primate Model of Cutaneous Leishmaniasis

Richard T. Kenney, David L. Sacks, Joseph P. Sypek, Luciano Vilela, Albert A. Gam, and Kamela Evans-Davis
J Immunol 1999 163: 4481-4488. [Abstract] [Full Text] [PDF]  

TNF Is Essential for the Cell-Mediated Protective Immunity Induced by the Radiation-Attenuated Schistosome Vaccine

Miyoko Street, Patricia S. Coulson, Clare Sadler, Lorna J. Warnock, Deborah McLaughlin, Horst Bluethmann, and R. Alan Wilson
J Immunol 1999 163: 4489-4494. [Abstract] [Full Text] [PDF]  

Surfactant Protein A Down-Regulates Proinflammatory Cytokine Production Evoked by Candida albicans in Human Alveolar Macrophages and Monocytes

Simone Rosseau, Peter Hammerl, Ulrich Maus, Andreas Günther, Werner Seeger, Friedrich Grimminger, and Jürgen Lohmeyer
J Immunol 1999 163: 4495-4502. [Abstract] [Full Text] [PDF]  

IL-15 Prolongs the Duration of CD8⁺ T Cell-Mediated Immunity in Mice Infected with a Vaccine Strain of Toxoplasma gondii

Imtiaz A. Khan and Lori Casciotti
J Immunol 1999 163: 4503-4509. [Abstract] [Full Text] [PDF]  

Effective DNA Vaccination Against Listeriosis by Prime/Boost Inoculation with the Gene Gun

Joachim Fensterle, Leander Grode, Jürgen Hess, and Stefan H. E. Kaufmann
J Immunol 1999 163: 4510-4518. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Nitric Oxide Participates in the Recovery of Normal Jejunal Epithelial Ion Transport Following Exposure to the Superantigen, Staphylococcus aureus Enterotoxin B

Derek M. McKay, Jun Lu, Sean Jedrzkiewicz, Winnie Ho, and Keith A. Sharkey
J Immunol 1999 163: 4519-4526. [Abstract] [Full Text] [PDF]  

Activation of p90^RSK and cAMP Response Element Binding Protein in Stimulated Neutrophils: Novel Effects of the Pyridinyl Imidazole SB 203580 on Activation of the Extracellular Signal-Regulated Kinase Cascade

Jian P. Lian, RiYun Huang, Dwight Robinson, and John A. Badwey
J Immunol 1999 163: 4527-4536. [Abstract] [Full Text] [PDF]  

Posttranscriptional Regulation of Acute Phase Serum Amyloid A2 Expression by the 5'- and 3'-Untranslated Regions of Its mRNA

Daniel B. Longley, Diana M. Steel, and Alexander S. Whitehead
J Immunol 1999 163: 4537-4545. [Abstract] [Full Text] [PDF]  

Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction

Erik Lubberts, Leo A. B. Joosten, Liduine van den Bersselaar, Monique M. A. Helsen, Andrew C. Bakker, Joyce B. J. van Meurs, Frank L. Graham, Carl D. Richards, and Wim B. van den Berg
J Immunol 1999 163: 4546-4556. [Abstract] [Full Text] [PDF]  

Activated Lymphocytes Promote Endothelial Cell Detachment from Matrix: A Role for Modulation of Endothelial Cell ß₁ Integrin Affinity

Cecile Phan, Alan W. McMahon, Randall C. Nelson, John F. Elliott, and Allan G. Murray
J Immunol 1999 163: 4557-4563. [Abstract] [Full Text] [PDF]  

Ectosomes Released by Human Neutrophils Are Specialized Functional Units

Christoph Hess, Salima Sadallah, Andreas Hefti, Regine Landmann, and Jürg-Alfred Schifferli
J Immunol 1999 163: 4564-4573. [Abstract] [Full Text] [PDF]  

Protein Kinase C (PKC) Isoforms Translocate to Triton-Insoluble Fractions in Stimulated Human Neutrophils: Correlation of Conventional PKC with Activation of NADPH Oxidase

Jennifer B. Nixon and Linda C. McPhail
J Immunol 1999 163: 4574-4582. [Abstract] [Full Text] [PDF]  

Novel Path to Activation of Vascular Smooth Muscle Cells: Up-Regulation of gp130 Creates an Autocrine Activation Loop by IL-6 and Its Soluble Receptor

Mariam Klouche, Sucharit Bhakdi, Monika Hemmes, and Stefan Rose-John
J Immunol 1999 163: 4583-4589. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Nephritogenic Light Chain Dimer: A Unique Human Miniautoantibody Against Complement Factor H

T. Sakari Jokiranta, Alan Solomon, Michael K. Pangburn, Peter F. Zipfel, and Seppo Meri
J Immunol 1999 163: 4590-4596. [Abstract] [Full Text] [PDF]  

CC Chemokine Receptor 5 Cell-Surface Expression in Relation to CC Chemokine Receptor 5 Genotype and the Clinical Course of HIV-1 Infection

Ana-Maria de Roda Husman, Hetty Blaak, Margreet Brouwer, and Hanneke Schuitemaker
J Immunol 1999 163: 4597-4603. [Abstract] [Full Text] [PDF]  

Isolation, Characterization and Sequence Analysis of Five IgG Monoclonal Anti-ß₂-Glycoprotein-1 and Anti-Prothrombin Antigen-Binding Fragments Generated by Phage Display

Reginald U. Chukwuocha, Elie T. Hsiao, Peter Shaw, Joseph L. Witztum, and Pojen P. Chen
J Immunol 1999 163: 4604-4611. [Abstract] [Full Text] [PDF]  

C1q-Containing Immune Complexes Purified from Sera of Juvenile Rheumatoid Arthritis Patients Mediate IL-8 Production by Human Synoviocytes: Role of C1q Receptors

Zhila Khalkhali-Ellis, Gary A. Bulla, Larry S. Schlesinger, Dawn A. Kirschmann, Terry L. Moore, and Mary J. C. Hendrix
J Immunol 1999 163: 4612-4620. [Abstract] [Full Text] [PDF]  

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