PRESIDENTIAL ADDRESS:

Presidential Address to The American Association of Immunologists : The Road Less Traveled by: The Role of Innate Immunity in the Adaptive Immune Response

Charles A. Janeway, Jr.
J Immunol 1998 161: 539-544. [Full Text] [PDF]  

IN MEMORIAM:

In Memoriam Marian Koshland 1921–1997

Jim Allison
J Immunol 1998 161: 545-546. [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: The Chemokine Receptor CCR8 Is Preferentially Expressed in Th2 But Not Th1 Cells

Alessandra Zingoni, Hortensia Soto, Joseph A. Hedrick, Antonella Stoppacciaro, Clelia T. Storlazzi, Francesco Sinigaglia, Daniele D’Ambrosio, Anne O’Garra, Douglas Robinson, Mariano Rocchi, Angela Santoni, Albert Zlotnik, and Monica Napolitano
J Immunol 1998 161: 547-551. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

The Efficiency of Antigen Recognition by CD8⁺ CTL Clones Is Determined by the Frequency of Serial TCR Engagement

Denis Hudrisier, Benedikt Kessler, Salvatore Valitutti, Clotilde Horvath, Jean-Charles Cerottini, and Immanuel F. Luescher
J Immunol 1998 161: 553-562. [Abstract] [Full Text] [PDF]  

Loss of Endogenous Mouse Mammary Tumor Virus Superantigen Increases Tumor Resistance

Volker Schirrmacher, Ulrich Beutner, Marianna Bucur, Victor Umansky, Marian Rocha, and Paul von Hoegen
J Immunol 1998 161: 563-570. [Abstract] [Full Text] [PDF]  

Direct Binding and Functional Transfer of NK Cell Inhibitory Receptors Reveal Novel Patterns of HLA-C Allotype Recognition

Christine C. Winter, Jenny E. Gumperz, Peter Parham, Eric O. Long, and Nicolai Wagtmann
J Immunol 1998 161: 571-577. [Abstract] [Full Text] [PDF]  

A Novel Type II Complement C2 Deficiency Allele in an African-American Family

Zeng-Bian Zhu, T. Prescott Atkinson, and John E. Volanakis
J Immunol 1998 161: 578-584. [Abstract] [Full Text] [PDF]  

TCR Transgenic Mice in Which Usage of Transgenic - and ß-Chains Is Highly Dependent on the Level of Selecting Ligand

Gilbert J. Kersh, David L. Donermeyer, Katherine E. Frederick, J. Michael White, Benjamin L. Hsu, and Paul M. Allen
J Immunol 1998 161: 585-593. [Abstract] [Full Text] [PDF]  

The Clonal Composition of a Peptide-Specific Oligoclonal CTL Repertoire Selected in Response to Persistent EBV Infection Is Stable Over Time

Victor Levitsky, Pedro-Otavio de Campos-Lima, Teresa Frisan, and Maria G. Masucci
J Immunol 1998 161: 594-601. [Abstract] [Full Text] [PDF]  

Cardiac Allografts from IL-4 Knockout Recipients: Assessment of Transplant Arteriosclerosis and Peripheral Tolerance

Patricia L. Mottram, Anne Räisänen-Sokolowski, Troels Glysing-Jensen, Alicia N. Stein-Oakley, and Mary E. Russell2
J Immunol 1998 161: 602-609. [Abstract] [Full Text] [PDF]  

Norepinephrine Accelerates HIV Replication Via Protein Kinase A-Dependent Effects on Cytokine Production

Steve W. Cole, Yael D. Korin, John L. Fahey, and Jerome A. Zack
J Immunol 1998 161: 610-616. [Abstract] [Full Text] [PDF]  

Relationship Between Peptide Selectivities of Human Transporters Associated with Antigen Processing and HLA Class I Molecules

Soizic Daniel, Vladimir Brusic, Sophie Caillat-Zucman, Nicolai Petrovsky, Leonard Harrison, Daniela Riganelli, Francesco Sinigaglia, Fabio Gallazzi, Jürgen Hammer, and Peter M. van Endert
J Immunol 1998 161: 617-624. [Abstract] [Full Text] [PDF]  

Growth Factor Receptor-Bound Protein 2 (Grb2) Association with Hemopoietic Specific Protein 1: Linkage Between Lck and Grb2

Yoshihiro Takemoto, Masaaki Furuta, Mitsuru Sato, Paul R. Findell, Wendy Ramble, and Yasuhiro Hashimoto
J Immunol 1998 161: 625-630. [Abstract] [Full Text] [PDF]  

Murine Graft-Versus-Host Disease in an F₁-Hybrid Model Using IFN- Gene Knockout Donors

Cynthia A. Ellison, Jacqie M. M. Fischer, Kent T. HayGlass, and John G. Gartner
J Immunol 1998 161: 631-640. [Abstract] [Full Text] [PDF]  

Alterations in Cell Surface Carbohydrates on T Cells from Virally Infected Mice Can Distinguish Effector/Memory CD8⁺ T Cells from Naive Cells

Marisa Galvan, Kaja Murali-Krishna, Lisa Lau Ming, Linda Baum, and Rafi Ahmed
J Immunol 1998 161: 641-648. [Abstract] [Full Text] [PDF]  

Inhibition of CD28/CD3-Mediated Costimulation of Naive and Memory Human T Lymphocytes by Intracellular Incorporation of Polyclonal Antibodies Specific for the Activator Protein-1 Transcriptional Complex

Darren G. Woodside and Bradley W. McIntyre
J Immunol 1998 161: 649-658. [Abstract] [Full Text] [PDF]  

Isolation and Analysis of a T Cell Clone Variant Exhibiting Constitutively Phosphorylated Ser¹³³ cAMP Response Element-Binding Protein

Stanley M. Belkowski, Charles S. Rubin, and Michael B. Prystowsky
J Immunol 1998 161: 659-665. [Abstract] [Full Text] [PDF]  

Deletion of a Recombined Ig Heavy Chain Transgene in B-Lineage Cells of Transgenic Mice

Andy Heinzelmann, Subbiah Kumar, Scott Noggle, Ine Goedegebuur, K. Morgan Sauer, Satyajit Rath, and Jeannine M. Durdik
J Immunol 1998 161: 666-673. [Abstract] [Full Text] [PDF]  

Qualitative Differences Between Naive and Memory T Cells Make a Major Contribution to the More Rapid and Efficient Memory CD8⁺ T Cell Response

Ross M. Kedl and Matthew F. Mescher
J Immunol 1998 161: 674-683. [Abstract] [Full Text] [PDF]  

B Cell Antigen Receptor (BCR)-Mediated Formation of a SHP-2-pp120 Complex and Its Inhibition by FeRIIB1-BCR Coligation

Kazuhiro Nakamura and John C. Cambier
J Immunol 1998 161: 684-691. [Abstract] [Full Text] [PDF]  

Antigen-Dependent Intrathecal Antibody Synthesis in the Normal Rat Brain: Tissue Entry and Local Retention of Antigen-Specific B Cells

Paul M. Knopf, Christine J. Harling-Berg, Helen F. Cserr, Devraj Basu, Erik J. Sirulnick, Scott C. Nolan, Joel T. Park, Geoffrey Keir, Edward J. Thompson, and William F. Hickey
J Immunol 1998 161: 692-701. [Abstract] [Full Text] [PDF]  

Carrier-Induced, Hapten-Specific Suppression: A Problem of Antigen Presentation?

Ximena Renjifo, Stanley Wolf, Paul-Pierre Pastoret, Hervé Bazin, Jacques Urbain, Oberdan Leo, and Muriel Moser
J Immunol 1998 161: 702-706. [Abstract] [Full Text] [PDF]  

The Role of IL-7 in Thymic and Extrathymic Development of TCR Cells

K. Laky, L. Lefrançois, U. von Freeden-Jeffry, R. Murray, and L. Puddington
J Immunol 1998 161: 707-713. [Abstract] [Full Text] [PDF]  

Following Antigen Challenge, T Cells Up-Regulate Cell Surface Expression of CD4 In Vitro and In Vivo

William Ridgway, Marcella Fassò, and C. Garrison Fathman
J Immunol 1998 161: 714-720. [Abstract] [Full Text] [PDF]  

Role of Maternal Ig in the Induction of C-Specific CD8⁺ T Cell Tolerance

Dominique Rueff-Juy, Mathias Faure, Anne-Marie Drapier, and Pierre-André Cazenave
J Immunol 1998 161: 721-728. [Abstract] [Full Text] [PDF]  

Anti-CD40L Accelerates Renal Disease and Adenopathy in MRL-lpr Mice in Parallel with Decreased Thymocyte Apoptosis

Jennifer Q. Russell, Thomas Mooney, Philip L. Cohen, Bruce MacPherson, Randolph J. Noelle, and Ralph C. Budd
J Immunol 1998 161: 729-739. [Abstract] [Full Text] [PDF]  

Identification of CD68⁺lin^- Peripheral Blood Cells with Dendritic Precursor Characteristics

Herbert Strobl, Clemens Scheinecker, Elisabeth Riedl, Bettina Csmarits, Concha Bello-Fernandez, Winfried F. Pickl, Otto Majdic, and Walter Knapp
J Immunol 1998 161: 740-748. [Abstract] [Full Text] [PDF]  

Engagement of CD99 Induces Up-Regulation of TCR and MHC Class I and II Molecules on the Surface of Human Thymocytes

Eun Young Choi, Weon Seo Park, Kyeong Cheon Jung, Soon Ha Kim, You Young Kim, Wang Jae Lee, and Seong Hoe Park
J Immunol 1998 161: 749-754. [Abstract] [Full Text] [PDF]  

NK Cells Can Recognize Different Forms of Class I MHC

Ruey-Chyi Su, Sam K. P. Kung, Jean Gariépy, Brian H. Barber, and Richard G. Miller
J Immunol 1998 161: 755-766. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Anti-MUC1 Antibodies React Directly with MUC1 Peptides Presented by Class I H2 and HLA Molecules

Vasso Apostolopoulos, Gareth Chelvanayagam, Pei-Xiang Xing, and Ian F. C. McKenzie
J Immunol 1998 161: 767-775. [Abstract] [Full Text] [PDF]  

HIV-Tat Protein Activates c-Jun N-Terminal Kinase and Activator Protein-1

Ashok Kumar, Sunil K. Manna, Subhash Dhawan, and Bharat B. Aggarwal
J Immunol 1998 161: 776-781. [Abstract] [Full Text] [PDF]  

Somatic Hypermutation of an Artificial Test Substrate Within an Ig Transgene

Emily L. Klotz, John Hackett, Jr., and Ursula Storb
J Immunol 1998 161: 782-790. [Abstract] [Full Text] [PDF]  

Regulatory Elements in the Promoter of a Murine TCRD V Gene Segment

Laura J. Kienker, Maya R. Ghosh, and Philip W. Tucker
J Immunol 1998 161: 791-804. [Abstract] [Full Text] [PDF]  

The Chemokine Monocyte Chemotactic Protein 1 Triggers Janus Kinase 2 Activation and Tyrosine Phosphorylation of the CCR2B Receptor

M. Mellado, J. M. Rodríguez-Frade, A. Aragay, G. del Real, A. M. Martín, A. J. Vila-Coro, A. Serrano, F. Mayor, Jr., and C. Martínez-A.
J Immunol 1998 161: 805-813. [Abstract] [Full Text] [PDF]  

HLA Class II Expression in Uninducible Hepatocarcinoma Cells After Transfection of AIR-1 Gene Product CIITA: Acquisition of Antigen Processing and Presentation Capacity

Silvia Sartoris, Maria Teresa Valle, Andrea De Lerma Barbaro, Giovanna Tosi, Tiziana Cestari, Antonella D’Agostino, Anna Maria Megiovanni, Fabrizio Manca, and Roberto S. Accolla2
J Immunol 1998 161: 814-820. [Abstract] [Full Text] [PDF]  

Expression Screening of a Yeast Artificial Chromosome Contig Refines the Location of the Mouse H3a Minor Histocompatibility Antigen Gene

Aamir R. Zuberi, Gregory J. Christianson, Sonal B. Dave, Julie A. Bradley, and Derry C. Roopenian
J Immunol 1998 161: 821-828. [Abstract] [Full Text] [PDF]  

Mapping Quantitative Trait Loci for Immune Capacity in the Pig

Inger Edfors-Lilja, Eva Wattrang, Lena Marklund, Maria Moller, Lena Andersson-Eklund, Leif Andersson, and Caroline Fossum
J Immunol 1998 161: 829-835. [Abstract] [Full Text] [PDF]  

Molecular Regulation of the Interaction Between Leukocyte Function-Associated Antigen-1 and Soluble ICAM-1 by Divalent Metal Cations

Mark E. Labadia, Deborah Durham Jeanfavre, Gary O. Caviness, and Maurice M. Morelock
J Immunol 1998 161: 836-842. [Abstract] [Full Text] [PDF]  

Potentiation by Thyroid Hormone of Human IFN--Induced HLA-DR Expression

Hung-Yun Lin, Leon J. Martino, Brian D. Wilcox, Faith B. Davis, Jennifer K. Gordinier, and Paul J. Davis
J Immunol 1998 161: 843-849. [Abstract] [Full Text] [PDF]  

Use of Complete Eluted Peptide Sequence Data from HLA-DR and -DQ Molecules to Predict T Cell Epitopes, and the Influence of the Nonbinding Terminal Regions of Ligands in Epitope Selection

Andrew J. Godkin, Miles P. Davenport, Anthony Willis, Derek P. Jewell, and Adrian V. S. Hill
J Immunol 1998 161: 850-858. [Abstract] [Full Text] [PDF]  

Regulation of Apoptosis by Tyrosine-Containing Domains of IL-4R: Y497 and Y713, But Not the STAT6-Docking Tyrosines, Signal Protection from Apoptosis

José Zamorano and Achsah D. Keegan
J Immunol 1998 161: 859-867. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Human Dendritic Cell (DC)-Based Anti-Infective Therapy: Engineering DCs to Secrete Functional IFN- and IL-12

Seema S. Ahuja, Srinivas Mummidi, Harry L. Malech, and Sunil K. Ahuja
J Immunol 1998 161: 868-876. [Abstract] [Full Text] [PDF]  

Stringent Allele/Epitope Requirements for MART-1/Melan A Immunodominance: Implications for Peptide-Based Immunotherapy

Maria P. Bettinotti, Christina J. Kim, Kang-Hun Lee, Matthew Roden, Janice N. Cormier, Monica Panelli, Kenneth K. Parker, and Francesco M. Marincola
J Immunol 1998 161: 877-889. [Abstract] [Full Text] [PDF]  

IL-2 and IL-4 Double Knockout Mice Reject Islet Allografts: A Role for Novel T Cell Growth Factors in Allograft Rejection

Xian Chang Li, Prabir Roy-Chaudhury, Wayne W. Hancock, Roberto Manfro, Martin S. Zand, Yongsheng Li, Xin Xiao Zheng, Peter W. Nickerson, Jurg Steiger, Thomas R. Malek, and Terry B. Strom
J Immunol 1998 161: 890-896. [Abstract] [Full Text] [PDF]  

T Cell-Mediated, IFN--Facilitated Rejection of Murine B16 Melanomas

Waltraud Böhm, Stefan Thoma, Frank Leithäuser, Peter Möller, Reinhold Schirmbeck, and Jörg Reimann
J Immunol 1998 161: 897-908. [Abstract] [Full Text] [PDF]  

T Cells Specific for a Polymorphic Segment of CD45 Induce Graft-Versus-Host Disease with Predominant Pulmonary Vasculitis

Wei Chen, Gurkamal S. Chatta, William D. Rubin, Joan G. Clark, Robert C. Hackman, David K. Madtes, Denny H. Ligitt, Yoichiro Kusunoki, Paul J. Martin, and Martin A. Cheever
J Immunol 1998 161: 909-918. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Resistance to Antigen-Induced Airway Hyperresponsiveness Requires Endogenous Production of IL-12

Andrea Keane-Myers, Maria Wysocka, Giorgio Trinchieri, and Marsha Wills-Karp
J Immunol 1998 161: 919-926. [Abstract] [Full Text] [PDF]  

The CXC Chemokines IP-10 and Mig Are Necessary for IL-12-Mediated Regression of the Mouse RENCA Tumor

Charles S. Tannenbaum, Raymond Tubbs, David Armstrong, James H. Finke, Ronald M. Bukowski, and Thomas A. Hamilton
J Immunol 1998 161: 927-932. [Abstract] [Full Text] [PDF]  

Phosphorylation of the Cytoplasmic Domain of E-Selectin Is Regulated During Leukocyte-Endothelial Adhesion

Masayuki Yoshida, Brian E. Szente, Jeanne-Marie Kiely, Anthony Rosenzweig, and Michael A. Gimbrone, Jr.
J Immunol 1998 161: 933-941. [Abstract] [Full Text] [PDF]  

Macrophage Activation by Polycyclic Aromatic Hydrocarbons: Evidence for the Involvement of Stress-Activated Protein Kinases, Activator Protein-1, and Antioxidant Response Elements

David Ng, Niels Kokot, Timothy Hiura, Mary Faris, Andrew Saxon, and Andre Nel
J Immunol 1998 161: 942-951. [Abstract] [Full Text] [PDF]  

Secondary Lymphoid-Tissue Chemokine (SLC) Stimulates Integrin ₄ß₇-Mediated Adhesion of Lymphocytes to Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1) Under Flow

Russell K. Pachynski, Steve W. Wu, Michael D. Gunn, and David J. Erle
J Immunol 1998 161: 952-956. [Abstract] [Full Text] [PDF]  

The IL-1ß-Converting Enzyme (Caspase-1) Inhibits Apoptosis of Inflammatory Neutrophils Through Activation of IL-1ß

R. William, G. Watson, Ori D. Rotstein, Jean Parodo, Richard Bitar, and John C. Marshall
J Immunol 1998 161: 957-962. [Abstract] [Full Text] [PDF]  

CD4⁺ T Cells Migrate into Inflamed Skin Only If They Express Ligands for E- and P-Selectin

Wolfgang Tietz, Yvonne Allemand, Eric Borges, Dorothea von Laer, Ruppert Hallmann, Dietmar Vestweber, and Alf Hamann
J Immunol 1998 161: 963-970. [Abstract] [Full Text] [PDF]  

Differential Regulation of Eosinophil Adhesion and Transmigration by Pulmonary Microvascular Endothelial Cells

Hideaki Yamamoto, Julie B. Sedgwick, and William W. Busse
J Immunol 1998 161: 971-977. [Abstract] [Full Text] [PDF]  

Inhibition of Inducible Nitric Oxide Synthase by Peroxisome Proliferator-Activated Receptor Agonists: Correlation with Induction of Heme Oxygenase 1

Paul R. Colville-Nash, Saima S. Qureshi, Dean Willis, and Derek A. Willoughby
J Immunol 1998 161: 978-984. [Abstract] [Full Text] [PDF]  

The Covalent Binding Reaction of Complement Component C3

Mihaela Gadjeva, Alister W. Dodds, Aiko Taniguchi-Sidle, Antony C. Willis, David E. Isenman, and S. K. Alex Law
J Immunol 1998 161: 985-990. [Abstract] [Full Text] [PDF]  

IL-12 Modulates Expression of Hypersensitivity Pneumonitis

Gunnar Gudmundsson, Martha M. Monick, and Gary W. Hunninghake
J Immunol 1998 161: 991-999. [Abstract] [Full Text] [PDF]  

Regulation of the High Affinity Receptor for IgE on Human Epidermal Langerhans Cells

Stefan Kraft, Jörg H. M. Weßendorf, Daniel Hanau, and Thomas Bieber
J Immunol 1998 161: 1000-1006. [Abstract] [Full Text] [PDF]  

Respiratory Syncytial Virus-Induced RANTES Production from Human Bronchial Epithelial Cells Is Dependent on Nuclear Factor-B Nuclear Binding and Is Inhibited by Adenovirus-Mediated Expression of Inhibitor of B

L. H. Thomas, J. S. Friedland, M. Sharland, and S. Becker
J Immunol 1998 161: 1007-1016. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Resistance to Apoptosis and Elevated Expression of Bcl-2 in Clonally Expanded CD4⁺CD28^- T Cells from Rheumatoid Arthritis Patients

Michael Schirmer, Abbe N. Vallejo, Cornelia M. Weyand, and Jörg J. Goronzy
J Immunol 1998 161: 1018-1025. [Abstract] [Full Text] [PDF]  

Monocytes from Wiskott-Aldrich Patients Display Reduced Chemotaxis and Lack of Cell Polarization in Response to Monocyte Chemoattractant Protein-1 and Formyl-Methionyl-Leucyl-Phenylalanine

Raffaele Badolato, Silvano Sozzani, Fabio Malacarne, Susanna Bresciani, Maurilia Fiorini, Alessandro Borsatti, Alberto Albertini, Alberto Mantovani, Alberto G. Ugazio, and Luigi D. Notarangelo
J Immunol 1998 161: 1026-1033. [Abstract] [Full Text] [PDF]  

Immunity to T Cell Receptor Peptides in Multiple Sclerosis. III. Preferential Immunogenicity of Complementarity-Determining Region 2 Peptides from Disease-Associated T Cell Receptor BV Genes

Dennis N. Bourdette, Yuan K. Chou, Ruth H. Whitham, Jane Buckner, Hi Jong Kwon, Gerald T. Nepom, Abigail Buenafe, Shelley A. Cooper, Mark Allegretta, George A. Hashim, Halina Offner, and Arthur A. Vandenbark
J Immunol 1998 161: 1034-1044. [Abstract] [Full Text] [PDF]  

Bacille Calmette-Guérin Vaccination Enhances Human T Cell Responsiveness to Mycobacteria Suggestive of a Memory-Like Phenotype

Daniel F. Hoft, Robin M. Brown, and Stanford T. Roodman
J Immunol 1998 161: 1045-1054. [Abstract] [Full Text] [PDF]  

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