CUTTING EDGE:

Commentary: Is CTLA-4 a master switch for peripheral T cell tolerance?

JA Bluestone
J Immunol 1997 158: 1989-1993. [Abstract] [PDF]  

Commentary: Down-modulation of c-myc expression induces apoptosis of B lymphocyte models of tolerance via clonal deletion

GE Sonenshein
J Immunol 1997 158: 1994-1997. [Abstract] [PDF]  

ARTICLES:

Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones

A Anel, S Gamen, MA Alava, AM Schmitt-Verhulst, A Pineiro, and J Naval
J Immunol 1997 158: 1999-2006. [Abstract] [PDF]  

Biochemical analysis of p120/130: a protein-tyrosine kinase substrate restricted to T and myeloid cells

AJ da Silva, JM Rosenfield, I Mueller, A Bouton, H Hirai, and CE Rudd
J Immunol 1997 158: 2007-2016. [Abstract] [PDF]  

Sequestration of p56(lck) by gp120, a model for TCR desensitization

F Goldman, J Crabtree, C Hollenback, and G Koretzky
J Immunol 1997 158: 2017-2024. [Abstract] [PDF]  

B7.2 expressed by T cells does not induce CD28-mediated costimulatory activity but retains CTLA4 binding: implications for induction of antitumor immunity to T cell tumors

EA Greenfield, E Howard, T Paradis, K Nguyen, F Benazzo, P McLean, P Hollsberg, G Davis, DA Hafler, AH Sharpe, GJ Freeman, and VK Kuchroo
J Immunol 1997 158: 2025-2034. [Abstract] [PDF]  

Phosphorylation of the NC-1.1 receptor and regulation of natural cytotoxicity by protein kinase C and cyclic GMP-dependent protein kinase

SP Holmgreen, X Wang, GR Clarke, RS Noltorp, TK Roberts, RC Burton, PJ Robinson, and YC Smart
J Immunol 1997 158: 2035-2041. [Abstract] [PDF]  

B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens

A Keane-Myers, WC Gause, PS Linsley, SJ Chen, and M Wills-Karp
J Immunol 1997 158: 2042-2049. [Abstract] [PDF]  

Overexpression of c-fos inhibits down-regulation of a cyclin-dependent kinase-2 inhibitor p27Kip1 in splenic B cells activated by surface Ig cross-linking

K Kobayashi, J Phuchareon, K Inada, Y Tomita, T Koizumi, M Hatano, S Miyatake, and T Tokuhisa
J Immunol 1997 158: 2050-2056. [Abstract] [PDF]  

Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses

DM La Face, C Couture, K Anderson, G Shih, J Alexander, A Sette, T Mustelin, A Altman, and HM Grey
J Immunol 1997 158: 2057-2064. [Abstract] [PDF]  

TGF-beta suppresses IFN-gamma induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression

YJ Lee, Y Han, HT Lu, V Nguyen, H Qin, PH Howe, BA Hocevar, JM Boss, RM Ransohoff, and EN Benveniste
J Immunol 1997 158: 2065-2075. [Abstract] [PDF]  

Phenotypes and invariant alpha beta TCR expression of peripheral V alpha 14+ NK T cells

K Masuda, Y Makino, J Cui, T Ito, T Tokuhisa, Y Takahama, H Koseki, K Tsuchida, T Koike, H Moriya, M Amano, and M Taniguchi
J Immunol 1997 158: 2076-2082. [Abstract] [PDF]  

The DNA-dependent protein kinase catalytic subunit (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells

KR McConnell, WS Dynan, and JA Hardin
J Immunol 1997 158: 2083-2089. [Abstract] [PDF]  

Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma

T Nakamura, RK Lee, SY Nam, BK Al-Ramadi, PA Koni, K Bottomly, ER Podack, and RA Flavell
J Immunol 1997 158: 2090-2098. [Abstract] [PDF]  

Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells

D Picarella, P Hurlbut, J Rottman, X Shi, E Butcher, and DJ Ringler
J Immunol 1997 158: 2099-2106. [Abstract] [PDF]  

MUC18/MCAM (CD146), an activation antigen of human T lymphocytes

WF Pickl, O Majdic, GF Fischer, P Petzelbauer, I Fae, M Waclavicek, J Stockl, C Scheinecker, T Vidicki, H Aschauer, JP Johnson, and W Knapp
J Immunol 1997 158: 2107-2115. [Abstract] [PDF]  

The nonpolymorphic MHC class II isotype, HLA-DQA2, is expressed on the surface of B lymphoblastoid cells

GB Rudy and AM Lew
J Immunol 1997 158: 2116-2125. [Abstract] [PDF]  

Lack of type 2 T cell-independent B cell responses and defect in isotype switching in TNF-lymphotoxin alpha-deficient mice

B Ryffel, F Di Padova, MH Schreier, M Le Hir, HP Eugster, and VF Quesniaux
J Immunol 1997 158: 2126-2133. [Abstract] [PDF]  

Dendritic cells that process and present nominal antigens to naive T lymphocytes are derived from CD2+ precursors

M Takamizawa, A Rivas, F Fagnoni, C Benike, J Kosek, H Hyakawa, and EG Engleman
J Immunol 1997 158: 2134-2142. [Abstract] [PDF]  

Nonclassical behavior of the mouse CD1 class I-like molecule

M Teitell, HR Holcombe, L Brossay, A Hagenbaugh, MJ Jackson, L Pond, SP Balk, C Terhorst, PA Peterson, and M Kronenberg
J Immunol 1997 158: 2143-2149. [Abstract] [PDF]  

Direct thymic involvement in anterior chamber-associated immune deviation: evidence for a nondeletional mechanism of centrally induced tolerance to extrathymic antigens in adult mice

Y Wang, I Goldschneider, D Foss, DY Wu, J O'Rourke, and RE Cone
J Immunol 1997 158: 2150-2155. [Abstract] [PDF]  

Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway

ES Woodle, DM Smith, JA Bluestone, WM Kirkman, 3rd, DR Green, and EW Skowronski
J Immunol 1997 158: 2156-2164. [Abstract] [PDF]  

Activation of the aryl hydrocarbon receptor/transcription factor and bone marrow stromal cell-dependent preB cell apoptosis

K Yamaguchi, RI Near, RA Matulka, A Shneider, P Toselli, AF Trombino, and DH Sherr
J Immunol 1997 158: 2165-2173. [Abstract] [PDF]  

Both resting and activated B lymphocytes expressing engineered peptide- Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients

ET Zambidis, RK Barth, and DW Scott
J Immunol 1997 158: 2174-2182. [Abstract] [PDF]  

Dominance of a single peptide bound to the class I(B) molecule, Qa-1b

A DeCloux, AS Woods, RJ Cotter, MJ Soloski, and J Forman
J Immunol 1997 158: 2183-2191. [Abstract] [PDF]  

Structural consequences of humanizing an antibody

MA Holmes and J Foote
J Immunol 1997 158: 2192-2201. [Abstract] [PDF]  

Definition of a large region of RAG1 that is important for coimmunoprecipitation of RAG2

CJ McMahan, MJ Sadofsky, and DG Schatz
J Immunol 1997 158: 2202-2210. [Abstract] [PDF]  

Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1

C Medesan, D Matesoi, C Radu, V Ghetie, and ES Ward
J Immunol 1997 158: 2211-2217. [Abstract] [PDF]  

A three-domain T cell receptor is biologically active and specifically stains cell surface MHC/peptide complexes

D Plaksin, K Polakova, P McPhie, and DH Margulies
J Immunol 1997 158: 2218-2227. [Abstract] [PDF]  

Chromatin structure of the lymphocyte Fc epsilon receptor gene (CD23): identification of an upstream transcriptional enhancer

WH Schubach, G Horvath, C LeVea, and J Tierney
J Immunol 1997 158: 2228-2235. [Abstract] [PDF]  

Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing

JC Solheim, MR Harris, CS Kindle, and TH Hansen
J Immunol 1997 158: 2236-2241. [Abstract] [PDF]  

Conjugation of human Fc gamma in closed-hinge or open-hinge configuration to Fab'gamma and analogous ligands

GT Stevenson, VA Anderson, KS Kan, and AT Worth
J Immunol 1997 158: 2242-2250. [Abstract] [PDF]  

AML1A and AML1B can transactivate the human IL-3 promoter

H Uchida, J Zhang, and SD Nimer
J Immunol 1997 158: 2251-2258. [Abstract] [PDF]  

Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice

WJ Dai, G Kohler, and F Brombacher
J Immunol 1997 158: 2259-2267. [Abstract] [PDF]  

Predominant appearance of NK1.1+ T cells producing IL-4 may be involved in the increased susceptibility of mice with the beige mutation during Salmonella infection

A Enomoto, H Nishimura, and Y Yoshikai
J Immunol 1997 158: 2268-2277. [Abstract] [PDF]  

Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization

DM Feltquate, S Heaney, RG Webster, and HL Robinson
J Immunol 1997 158: 2278-2284. [Abstract] [PDF]  

The role of the CD28/B7 interaction in the regulation of NK cell responses during infection with Toxoplasma gondii

CA Hunter, L Ellis-Neyer, KE Gabriel, MK Kennedy, KH Grabstein, PS Linsley, and JS Remington
J Immunol 1997 158: 2285-2293. [Abstract] [PDF]  

Early T cell unresponsiveness in mice with candidiasis and reversal by IL-2: effect on T helper cell development

R Spaccapelo, G Del Sero, P Mosci, F Bistoni, and L Romani
J Immunol 1997 158: 2294-2302. [Abstract] [PDF]  

Lethal effect of recombinant human Fas ligand in mice pretreated with Propionibacterium acnes

M Tanaka, T Suda, T Yatomi, N Nakamura, and S Nagata
J Immunol 1997 158: 2303-2309. [Abstract] [PDF]  

Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis

BL Gruber, RR Kew, A Jelaska, MJ Marchese, J Garlick, S Ren, LB Schwartz, and JH Korn
J Immunol 1997 158: 2310-2317. [Abstract] [PDF]  

Regulation of brain-derived T cells during acute central nervous system inflammation

DN Irani, KI Lin, and DE Griffin
J Immunol 1997 158: 2318-2326. [Abstract] [PDF]  

Cytokine and chemokine regulation of proMMP-9 and TIMP-1 production by human peripheral blood lymphocytes

RN Johnatty, DD Taub, SP Reeder, SM Turcovski-Corrales, DW Cottam, TJ Stephenson, and RC Rees
J Immunol 1997 158: 2327-2333. [Abstract] [PDF]  

Substance P-induced IL-12 production by murine macrophages

T Kincy-Cain and KL Bost
J Immunol 1997 158: 2334-2339. [Abstract] [PDF]  

Contrasting responses to multiple chemotactic stimuli in transendothelial migration: heterologous desensitization in neutrophils and augmentation of migration in eosinophils

J Kitayama, MW Carr, SJ Roth, J Buccola, and TA Springer
J Immunol 1997 158: 2340-2349. [Abstract] [PDF]  

Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells

H Nishizumi and T Yamamoto
J Immunol 1997 158: 2350-2355. [Abstract] [PDF]  

An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasis

L Romani, A Mencacci, E Cenci, G Del Sero, F Bistoni, and P Puccetti
J Immunol 1997 158: 2356-2362. [Abstract] [PDF]  

Regulation of IFN-alpha/beta, MxA, 2',5'-oligoadenylate synthetase, and HLA gene expression in influenza A-infected human lung epithelial cells

T Ronni, S Matikainen, T Sareneva, K Melen, J Pirhonen, P Keskinen, and I Julkunen
J Immunol 1997 158: 2363-2374. [Abstract] [PDF]  

Nitric oxide, an autocrine regulator of wound fibroblast synthetic function

MR Schaffer, PA Efron, FJ Thornton, K Klingel, SS Gross, and A Barbul
J Immunol 1997 158: 2375-2381. [Abstract] [PDF]  

Increased secretion of TNF-alpha by costimulation of mast cells via CD28 and Fc epsilon RI

M Tashiro, Y Kawakami, R Abe, W Han, D Hata, K Sugie, L Yao, and T Kawakami
J Immunol 1997 158: 2382-2389. [Abstract] [PDF]  

Activation of the phosphatidylinositol 3-kinase serine kinase by IFN- alpha

S Uddin, EN Fish, DA Sher, C Gardziola, MF White, and LC Platanias
J Immunol 1997 158: 2390-2397. [Abstract] [PDF]  

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

T Weiss, M Grell, B Hessabi, S Bourteele, G Muller, P Scheurich, and H Wajant
J Immunol 1997 158: 2398-2404. [Abstract] [PDF]  

Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern

D Diaz-Sanchez, A Tsien, J Fleming, and A Saxon
J Immunol 1997 158: 2406-2413. [Abstract] [PDF]  

IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice

CJ Fox and JS Danska
J Immunol 1997 158: 2414-2424. [Abstract] [PDF]  

Down-regulation of poison ivy/oak-induced contact sensitivity by treatment with a class II MHC binding peptide:hapten conjugate

C Gelber, L Gemmell, D McAteer, M Homola, P Swain, A Liu, KJ Wilson, and M Gefter
J Immunol 1997 158: 2425-2434. [Abstract] [PDF]  

Patterns of hemopoietic reconstitution in nonobese diabetic mice: dichotomy of allogeneic resistance versus competitive advantage of disease-resistant marrow

CL Kaufman, H Li, and ST Ildstad
J Immunol 1997 158: 2435-2442. [Abstract] [PDF]  

Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4

FG Lakkis, BT Konieczny, S Saleem, FK Baddoura, PS Linsley, DZ Alexander, RP Lowry, TC Pearson, and CP Larsen
J Immunol 1997 158: 2443-2448. [Abstract] [PDF]  

Proinflammatory cytokines inhibit HIV-1(SF162) expression in acutely infected human brain cell cultures

JR Lokensgard, G Gekker, LC Ehrlich, S Hu, CC Chao, and PK Peterson
J Immunol 1997 158: 2449-2455. [Abstract] [PDF]  

Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection

N Oyaizu, Y Adachi, F Hashimoto, TW McCloskey, N Hosaka, N Kayagaki, H Yagita, and S Pahwa
J Immunol 1997 158: 2456-2463. [Abstract] [PDF]  

alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity

SL Peng, JM McNiff, MP Madaio, J Ma, MJ Owen, RA Flavell, AC Hayday, and J Craft
J Immunol 1997 158: 2464-2470. [Abstract] [PDF]  

Modulation of the immune response in multiple sclerosis: production of monoclonal antibodies specific to HLA/myelin basic protein

J Puri, R Arnon, E Gurevich, and D Teitelbaum
J Immunol 1997 158: 2471-2476. [Abstract] [PDF]  

VHDJH gene sequences and antigen reactivity of monoclonal antibodies produced by human B-1 cells: evidence for somatic selection

EW Schettino, SK Chai, MT Kasaian, HW Schroeder, Jr, and P Casali
J Immunol 1997 158: 2477-2489. [Abstract] [PDF]  

Eosinophils are not required for the rejection of neovascularized fetal pig proislet xenografts in mice

CJ Simeonovic, MJ Townsend, JD Wilson, KU McKenzie, AJ Ramsay, KI Matthaei, DA Mann, and IG Young
J Immunol 1997 158: 2490-2499. [Abstract] [PDF]  

Dichotomy of blood- and skin-derived IL-4-producing allergen-specific T cells and restricted V beta repertoire in nickel-mediated contact dermatitis

T Werfel, M Hentschel, A Kapp, and H Renz
J Immunol 1997 158: 2500-2505. [Abstract] [PDF]  

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