The Journal of Immunology: 195 (4)

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August 15, 2015; Volume 195,Issue 4

IN THIS ISSUE

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In This Issue
Gauging γδ T Cell Groupings See article p. 1449
Hostile NK Cells Educate Themselves See article p. 1506
HDAC3 Helps Teenage T Cells Mature See article p. 1578
Lysosomes and Lyme Arthritis See article p. 1647
Helping T Cells Remember Chlamydia See article p. 1665
Incognito IL-1R Antagonist See article p. 1705

J Immunol August 15, 2015, 195 (4) 1337-1338; DOI: https://doi.org/10.4049/jimmunol.1590015

LETTERS TO THE EDITOR

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Comment on “Aminoacyl tRNA Synthetase–Interacting Multifunctional Protein 1 Acts as a Novel B Cell–Activating Factor In Vitro and In Vivo”
Philip L. Cohen

J Immunol August 15, 2015, 195 (4) 1339; DOI: https://doi.org/10.4049/jimmunol.1501167

TRANSLATING IMMUNOLOGY

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G-CSF and GM-CSF in Neutropenia
Hrishikesh M. Mehta, Michael Malandra and Seth J. Corey

J Immunol August 15, 2015, 195 (4) 1341-1349; DOI: https://doi.org/10.4049/jimmunol.1500861

BRIEF REVIEWS

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T Cell Adolescence: Maturation Events Beyond Positive Selection
Kristin A. Hogquist, Yan Xing, Fan-Chi Hsu and Virginia Smith Shapiro

J Immunol August 15, 2015, 195 (4) 1351-1357; DOI: https://doi.org/10.4049/jimmunol.1501050

CUTTING EDGE

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Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α
Jennie Chan, Maninjay Atianand, Zhaozhao Jiang, Susan Carpenter, Daniel Aiello, Roland Elling, Katherine A. Fitzgerald and Daniel R. Caffrey

J Immunol August 15, 2015, 195 (4) 1359-1363; DOI: https://doi.org/10.4049/jimmunol.1500264
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Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells
Hannah G. Polikowsky, Cara E. Wogsland, Kirsten E. Diggins, Kanutte Huse and Jonathan M. Irish

J Immunol August 15, 2015, 195 (4) 1364-1367; DOI: https://doi.org/10.4049/jimmunol.1500904
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Cutting Edge: Retinoic Acid Signaling in B Cells Is Essential for Oral Immunization and Microflora Composition
Eirini Pantazi, Ellen Marks, Emilie Stolarczyk, Nils Lycke, Randolph J. Noelle and Raul Elgueta

J Immunol August 15, 2015, 195 (4) 1368-1371; DOI: https://doi.org/10.4049/jimmunol.1500989
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Cutting Edge: Hypoxia-Inducible Factor 1 Negatively Regulates Th1 Function
Hussein Shehade, Valérie Acolty, Muriel Moser and Guillaume Oldenhove

J Immunol August 15, 2015, 195 (4) 1372-1376; DOI: https://doi.org/10.4049/jimmunol.1402552

ALLERGY AND OTHER HYPERSENSITIVITIES

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Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation
Hiam Abdala-Valencia, Paul J. Bryce, Robert P. Schleimer, Joshua B. Wechsler, Lucas F. Loffredo, Joan M. Cook-Mills, Chia-Lin Hsu and Sergejs Berdnikovs

J Immunol August 15, 2015, 195 (4) 1377-1387; DOI: https://doi.org/10.4049/jimmunol.1302874
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Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells
Kondababu Kurakula, Mariska Vos, Adrian Logiantara, Joris J. Roelofs, Maartje A. Nieuwenhuis, Gerard H. Koppelman, Dirkje S. Postma, Leonie S. van Rijt and Carlie J. M. de Vries

J Immunol August 15, 2015, 195 (4) 1388-1398; DOI: https://doi.org/10.4049/jimmunol.1401714

AUTOIMMUNITY

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Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3-Independent T Cells with Suppressive Properties
Inna V. Grishkan, Dominique M. Tosi, Melissa D. Bowman, Maya Harary, Peter A. Calabresi and Anne R. Gocke

J Immunol August 15, 2015, 195 (4) 1399-1407; DOI: https://doi.org/10.4049/jimmunol.1403024
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IL-17–Producing Vγ4⁺ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions
Yasuhiro Maeda, Noriyasu Seki, Hirotoshi Kataoka, Kana Takemoto, Hiroyuki Utsumi, Atsushi Fukunari, Kunio Sugahara and Kenji Chiba

J Immunol August 15, 2015, 195 (4) 1408-1416; DOI: https://doi.org/10.4049/jimmunol.1500599

CLINICAL AND HUMAN IMMUNOLOGY

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Circulating Human CD27⁻IgA⁺ Memory B Cells Recognize Bacteria with Polyreactive Igs
Magdalena A. Berkowska, Jean-Nicolas Schickel, Christina Grosserichter-Wagener, Dick de Ridder, Yen Shing Ng, Jacques J. M. van Dongen, Eric Meffre and Menno C. van Zelm

J Immunol August 15, 2015, 195 (4) 1417-1426; DOI: https://doi.org/10.4049/jimmunol.1402708
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The B Cell–Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell–Dependent Bone Loss in Experimental Murine Periodontitis
Toshiharu Abe, Mohammed AlSarhan, Manjunatha R. Benakanakere, Tomoki Maekawa, Denis F. Kinane, Michael P. Cancro, Jonathan M. Korostoff and George Hajishengallis

J Immunol August 15, 2015, 195 (4) 1427-1435; DOI: https://doi.org/10.4049/jimmunol.1500496

IMMUNE REGULATION

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Adenosine Modulates NR4A Orphan Nuclear Receptors To Attenuate Hyperinflammatory Responses in Monocytic Cells
Daniel Crean, Eoin P. Cummins, Bojlul Bahar, Helen Mohan, Jason P. McMorrow and Evelyn P. Murphy

J Immunol August 15, 2015, 195 (4) 1436-1448; DOI: https://doi.org/10.4049/jimmunol.1402039
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Adaptive Immune-like γ/δ T Lymphocytes Share Many Common Features with Their α/β T Cell Counterparts
Amélie Lombes, Aurélie Durand, Céline Charvet, Matthieu Rivière, Nelly Bonilla, Cédric Auffray, Bruno Lucas and Bruno Martin

J Immunol August 15, 2015, 195 (4) 1449-1458; DOI: https://doi.org/10.4049/jimmunol.1500375
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A Subset of CD8αβ⁺ Invariant NKT Cells in a Humanized Mouse Model
Xiangshu Wen, Seil Kim, Ran Xiong, Michelle Li, Agnieszka Lawrenczyk, Xue Huang, Si-Yi Chen, Ping Rao, Gurdyal S. Besra, Paolo Dellabona, Giulia Casorati, Steven A. Porcelli, Omid Akbari, Mark A. Exley and Weiming Yuan

J Immunol August 15, 2015, 195 (4) 1459-1469; DOI: https://doi.org/10.4049/jimmunol.1500574
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mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function
Steven A. Schaffert, Christina Loh, Song Wang, Christopher P. Arnold, Robert C. Axtell, Evan W. Newell, Garry Nolan, K. Mark Ansel, Mark M. Davis, Lawrence Steinman and Chang-Zheng Chen

J Immunol August 15, 2015, 195 (4) 1470-1479; DOI: https://doi.org/10.4049/jimmunol.1401587
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Dual Function of the IRF8 Transcription Factor in Autoimmune Uveitis: Loss of IRF8 in T Cells Exacerbates Uveitis, Whereas Irf8 Deletion in the Retina Confers Protection
Sung-Hye Kim, Jenna Burton, Cheng-Rong Yu, Lin Sun, Chang He, Hongsheng Wang, Herbert C. Morse and Charles E. Egwuagu

J Immunol August 15, 2015, 195 (4) 1480-1488; DOI: https://doi.org/10.4049/jimmunol.1500653
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Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression
Andrew Jones, Adeleye Opejin, Jacob G. Henderson, Cindy Gross, Rajan Jain, Jonathan A. Epstein, Richard A. Flavell and Daniel Hawiger

J Immunol August 15, 2015, 195 (4) 1489-1497; DOI: https://doi.org/10.4049/jimmunol.1500174
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DC-SCRIPT Regulates IL-10 Production in Human Dendritic Cells by Modulating NF-κBp65 Activation
Jonas Nørskov Søndergaard, Susanna Poghosyan, Saartje Hontelez, Pauline Louche, Maaike W. G. Looman, Marleen Ansems and Gosse J. Adema

J Immunol August 15, 2015, 195 (4) 1498-1505; DOI: https://doi.org/10.4049/jimmunol.1402924

IMMUNE SYSTEM DEVELOPMENT

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Prenatal Allospecific NK Cell Tolerance Hinges on Instructive Allorecognition through the Activating Receptor during Development
Amir M. Alhajjat, Beverly S. Strong, Amanda E. Lee, Lucas E. Turner, Ram K. Wadhwani, John R. Ortaldo, Jonathan W. Heusel and Aimen F. Shaaban

J Immunol August 15, 2015, 195 (4) 1506-1516; DOI: https://doi.org/10.4049/jimmunol.1500463
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Restriction of Nonpermissive RUNX3 Protein Expression in T Lymphocytes by the Kozak Sequence
Byungil Kim, Yo Sasaki and Takeshi Egawa

J Immunol August 15, 2015, 195 (4) 1517-1523; DOI: https://doi.org/10.4049/jimmunol.1501039
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VprBP Is Required for Efficient Editing and Selection of Igκ⁺ B Cells, but Is Dispensable for Igλ⁺ and Marginal Zone B Cell Maturation and Selection
Victoria L. Palmer, Razia Aziz-Seible, Michele D. Kassmeier, Mary Rothermund, Greg A. Perry and Patrick C. Swanson

J Immunol August 15, 2015, 195 (4) 1524-1537; DOI: https://doi.org/10.4049/jimmunol.1500952
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Histone Arginine Methylation by PRMT7 Controls Germinal Center Formation via Regulating Bcl6 Transcription
Zhengzhou Ying, Mei Mei, Peizhun Zhang, Chunyi Liu, Huacheng He, Fei Gao and Shilai Bao

J Immunol August 15, 2015, 195 (4) 1538-1547; DOI: https://doi.org/10.4049/jimmunol.1500224
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Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells
Susann Hüttl, Kathrin Kläsener, Michaela Schweizer, Janna Schneppenheim, Hans-Heinrich Oberg, Dieter Kabelitz, Michael Reth, Paul Saftig and Bernd Schröder

J Immunol August 15, 2015, 195 (4) 1548-1563; DOI: https://doi.org/10.4049/jimmunol.1403171
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Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance
Kyle Leonard O’Hagan, Jinyong Choi, Olga Pryshchep, Jonathan Chernoff and Hyewon Phee

J Immunol August 15, 2015, 195 (4) 1564-1577; DOI: https://doi.org/10.4049/jimmunol.1500843
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Histone Deacetylase 3 Is Required for T Cell Maturation
Fan-Chi Hsu, Paul J. Belmonte, Megan M. Constans, Meibo W. Chen, Douglas C. McWilliams, Scott W. Hiebert and Virginia Smith Shapiro

J Immunol August 15, 2015, 195 (4) 1578-1590; DOI: https://doi.org/10.4049/jimmunol.1500435
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Persistent Antigen and Prolonged AKT–mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells
Yingzhong Li, Chase Shen, Bingdong Zhu, Feng Shi, Herman N. Eisen and Jianzhu Chen

J Immunol August 15, 2015, 195 (4) 1591-1598; DOI: https://doi.org/10.4049/jimmunol.1500451

IMMUNOGENETICS

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Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy
Jin Li, Irene Fung, Joseph T. Glessner, Rahul Pandey, Zhi Wei, Marina Bakay, Frank D. Mentch, Renata Pellegrino, Tiancheng Wang, Cecilia Kim, Cuiping Hou, Fengxiang Wang, Rosetta M. Chiavacci, Kelly A. Thomas, Jonathan M. Spergel, Hakon Hakonarson and Patrick M. A. Sleiman

J Immunol August 15, 2015, 195 (4) 1599-1607; DOI: https://doi.org/10.4049/jimmunol.1402310
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An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development
Christophe Pedros, Guillaume Gaud, Isabelle Bernard, Sahar Kassem, Marianne Chabod, Dominique Lagrange, Olivier Andréoletti, Anne S. Dejean, Renaud Lesourne, Gilbert J. Fournié and Abdelhadi Saoudi

J Immunol August 15, 2015, 195 (4) 1608-1616; DOI: https://doi.org/10.4049/jimmunol.1402562

IMMUNOTHERAPY AND VACCINES

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Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination
Giuseppe Lofano, Francesca Mancini, Giulia Salvatore, Rocco Cantisani, Elisabetta Monaci, Corrado Carrisi, Simona Tavarini, Chiara Sammicheli, Silvia Rossi Paccani, Elisabetta Soldaini, Donatello Laera, Oretta Finco, Sandra Nuti, Rino Rappuoli, Ennio De Gregorio, Fabio Bagnoli and Sylvie Bertholet

J Immunol August 15, 2015, 195 (4) 1617-1627; DOI: https://doi.org/10.4049/jimmunol.1402604

INFECTIOUS DISEASE AND HOST RESPONSE

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Natural Anti-Infective Pulmonary Proteins: In Vivo Cooperative Action of Surfactant Protein SP-A and the Lung Antimicrobial Peptide SP-B^N
Juan Manuel Coya, Henry T. Akinbi, Alejandra Sáenz, Li Yang, Timothy E. Weaver and Cristina Casals

J Immunol August 15, 2015, 195 (4) 1628-1636; DOI: https://doi.org/10.4049/jimmunol.1500778
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Sirtuin 1 Regulates Dendritic Cell Activation and Autophagy during Respiratory Syncytial Virus–Induced Immune Responses
Anna B. Owczarczyk, Matthew A. Schaller, Michelle Reed, Andrew J. Rasky, David B. Lombard and Nicholas W. Lukacs

J Immunol August 15, 2015, 195 (4) 1637-1646; DOI: https://doi.org/10.4049/jimmunol.1500326
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β-Glucuronidase, a Regulator of Lyme Arthritis Severity, Modulates Lysosomal Trafficking and MMP-9 Secretion in Response to Inflammatory Stimuli
Kenneth K. C. Bramwell, Kelton Mock, Ying Ma, John H. Weis, Cory Teuscher and Janis J. Weis

J Immunol August 15, 2015, 195 (4) 1647-1656; DOI: https://doi.org/10.4049/jimmunol.1500212
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Adaptive Immunity against Streptococcus pyogenes in Adults Involves Increased IFN-γ and IgG3 Responses Compared with Children
Rasmus Mortensen, Thomas Nørrelykke Nissen, Thomas Blauenfeldt, Jan P. Christensen, Peter Andersen and Jes Dietrich

J Immunol August 15, 2015, 195 (4) 1657-1664; DOI: https://doi.org/10.4049/jimmunol.1500804
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An Excess of the Proinflammatory Cytokines IFN-γ and IL-12 Impairs the Development of the Memory CD8⁺ T Cell Response to Chlamydia trachomatis
Xuqing Zhang and Michael N. Starnbach

J Immunol August 15, 2015, 195 (4) 1665-1675; DOI: https://doi.org/10.4049/jimmunol.1500457
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NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation
Manuela Moraru, Laurel E. Black, Aura Muntasell, Francisca Portero, Miguel López-Botet, Hugh T. Reyburn, Janardan P. Pandey and Carlos Vilches

J Immunol August 15, 2015, 195 (4) 1676-1684; DOI: https://doi.org/10.4049/jimmunol.1500872

INNATE IMMUNITY AND INFLAMMATION

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Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
Gregory M. Orlowski, Jeff D. Colbert, Shruti Sharma, Matthew Bogyo, Stephanie A. Robertson and Kenneth L. Rock

J Immunol August 15, 2015, 195 (4) 1685-1697; DOI: https://doi.org/10.4049/jimmunol.1500509
Open Access
Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1
Author Choice Article

Rada Ellegård, Elisa Crisci, Jonas Andersson, Esaki M. Shankar, Sofia Nyström, Jorma Hinkula and Marie Larsson

J Immunol August 15, 2015, 195 (4) 1698-1704; DOI: https://doi.org/10.4049/jimmunol.1500618
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IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation
Peleg Rider, Yaron Carmi, Rami Yossef, Ofer Guttman, Hadar Eini, Tania Azam, Charles A. Dinarello and Eli C. Lewis

J Immunol August 15, 2015, 195 (4) 1705-1712; DOI: https://doi.org/10.4049/jimmunol.1501168
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Differential TGF-β Signaling in Glial Subsets Underlies IL-6–Mediated Epileptogenesis in Mice
Nitzan Levy, Dan Z. Milikovsky, Gytis Baranauskas, Ekaterina Vinogradov, Yaron David, Maya Ketzef, Shai Abutbul, Itai Weissberg, Lyn Kamintsky, Ilya Fleidervish, Alon Friedman and Alon Monsonego

J Immunol August 15, 2015, 195 (4) 1713-1722; DOI: https://doi.org/10.4049/jimmunol.1401446
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Opposing Roles of Dectin-1 Expressed on Human Plasmacytoid Dendritic Cells and Myeloid Dendritic Cells in Th2 Polarization
HyeMee Joo, Katherine Upchurch, Wei Zhang, Ling Ni, Dapeng Li, Yaming Xue, Xiao-Hua Li, Toshiyuki Hori, Sandra Zurawski, Yong-Jun Liu, Gerard Zurawski and SangKon Oh

J Immunol August 15, 2015, 195 (4) 1723-1731; DOI: https://doi.org/10.4049/jimmunol.1402276
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Differential Tissue-Specific Function of Adora2b in Cardioprotection
Seong-wook Seo, Michael Koeppen, Stephanie Bonney, Merit Gobel, Molly Thayer, Patrick N. Harter, Katya Ravid, Holger K. Eltzschig, Michel Mittelbronn, Lori Walker and Tobias Eckle

J Immunol August 15, 2015, 195 (4) 1732-1743; DOI: https://doi.org/10.4049/jimmunol.1402288
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IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine
Armanda J. Onderdijk, Ewout M. Baerveldt, Dorota Kurek, Marius Kant, Edwin F. Florencia, Reno Debets and Errol P. Prens

J Immunol August 15, 2015, 195 (4) 1744-1752; DOI: https://doi.org/10.4049/jimmunol.1401740
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Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production
Magdalena Niedzielska, Faizal A. M. Raffi, Jurjen Tel, Sandra Muench, Katrin Jozefowski, Nour Alati, Katharina Lahl, Jörg Mages, Ulrike Billmeier, Matthias Schiemann, Uwe K. Appelt, Stefan Wirtz, Tim Sparwasser, Hubertus Hochrein, Carl G. Figdor, Stephen M. Keyse and Roland Lang

J Immunol August 15, 2015, 195 (4) 1753-1762; DOI: https://doi.org/10.4049/jimmunol.1400658
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Langerhans Cell–Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1
Linda M. van den Berg, Sylvain Cardinaud, Angelic M. G. van der Aar, Joris K. Sprokholt, Marein A. W. P. de Jong, Esther M. Zijlstra-Willems, Arnaud Moris and Teunis B. H. Geijtenbeek

J Immunol August 15, 2015, 195 (4) 1763-1773; DOI: https://doi.org/10.4049/jimmunol.1402356
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Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development
Chie Sugimoto, Atsuhiko Hasegawa, Yohei Saito, Yayoi Fukuyo, Kevin B. Chiu, Yanhui Cai, Matthew W. Breed, Kazuyasu Mori, Chad J. Roy, Andrew A. Lackner, Woong-Ki Kim, Elizabeth S. Didier and Marcelo J. Kuroda

J Immunol August 15, 2015, 195 (4) 1774-1781; DOI: https://doi.org/10.4049/jimmunol.1500522
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pVHL Negatively Regulates Antiviral Signaling by Targeting MAVS for Proteasomal Degradation
Juan Du, Dawei Zhang, Wei Zhang, Gang Ouyang, Jing Wang, Xing Liu, Shun Li, Wei Ji, Wei Liu and Wuhan Xiao

J Immunol August 15, 2015, 195 (4) 1782-1790; DOI: https://doi.org/10.4049/jimmunol.1500588

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Foxo1 Is a T Cell–Intrinsic Inhibitor of the RORγt-Th17 Program
Alexandra Lainé, Bruno Martin, Marine Luka, Lucile Mir, Cédric Auffray, Bruno Lucas, Georges Bismuth and Céline Charvet

J Immunol August 15, 2015, 195 (4) 1791-1803; DOI: https://doi.org/10.4049/jimmunol.1500849
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STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRγ Locus
Keisuke Wagatsuma, Shizue Tani-ichi, Bingfei Liang, Soichiro Shitara, Ko Ishihara, Manabu Abe, Hitoshi Miyachi, Satsuki Kitano, Takahiro Hara, Masanobu Nanno, Hiromichi Ishikawa, Kenji Sakimura, Mitsuyoshi Nakao, Hiroshi Kimura and Koichi Ikuta

J Immunol August 15, 2015, 195 (4) 1804-1814; DOI: https://doi.org/10.4049/jimmunol.1302456

MUCOSAL IMMUNOLOGY

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Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury
Sandra Hoegl, Kelley S. Brodsky, Michael R. Blackburn, Harry Karmouty-Quintana, Bernhard Zwissler and Holger K. Eltzschig

J Immunol August 15, 2015, 195 (4) 1815-1824; DOI: https://doi.org/10.4049/jimmunol.1401957
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Identification of Teleost Skin CD8α⁺ Dendritic-like Cells, Representing a Potential Common Ancestor for Mammalian Cross-Presenting Dendritic Cells
Aitor G. Granja, Esther Leal, Jaime Pignatelli, Rosario Castro, Beatriz Abós, Goshi Kato, Uwe Fischer and Carolina Tafalla

J Immunol August 15, 2015, 195 (4) 1825-1837; DOI: https://doi.org/10.4049/jimmunol.1500322

TRANSPLANTATION

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Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8⁺ T Cell Hyporesponsiveness to Alloantigen
Emmy L. D. de Mare-Bredemeijer, Xiao-lei Shi, Shanta Mancham, Rogier van Gent, Marieke van der Heide-Mulder, Renate de Boer, Mirjam H. M. Heemskerk, Jeroen de Jonge, Luc J. W. van der Laan, Herold J. Metselaar and Jaap Kwekkeboom

J Immunol August 15, 2015, 195 (4) 1838-1848; DOI: https://doi.org/10.4049/jimmunol.1500440
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Valproic Acid Ameliorates Graft-versus-Host Disease by Downregulating Th1 and Th17 Cells
Jun Long, Li Chang, Yan Shen, Wen-Hui Gao, Yue-Nv Wu, Han-Bo Dou, Meng-Meng Huang, Ying Wang, Wei-Yue Fang, Jie-Hui Shan, Yue-Ying Wang, Jiang Zhu, Zhu Chen and Jiong Hu

J Immunol August 15, 2015, 195 (4) 1849-1857; DOI: https://doi.org/10.4049/jimmunol.1500578

TUMOR IMMUNOLOGY

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Galectin-3 Binding Protein Secreted by Breast Cancer Cells Inhibits Monocyte-Derived Fibrocyte Differentiation
Michael J. V. White, David Roife and Richard H. Gomer

J Immunol August 15, 2015, 195 (4) 1858-1867; DOI: https://doi.org/10.4049/jimmunol.1500365
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H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance
Amy V. Paschall, Dafeng Yang, Chunwan Lu, Jeong-Hyeon Choi, Xia Li, Feiyan Liu, Mario Figueroa, Nicholas H. Oberlies, Cedric Pearce, Wendy B. Bollag, Asha Nayak-Kapoor and Kebin Liu

J Immunol August 15, 2015, 195 (4) 1868-1882; DOI: https://doi.org/10.4049/jimmunol.1402243
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Innate Response to Human Cancer Cells with or without IL-2 Receptor Common γ-Chain Function in NOD Background Mice Lacking Adaptive Immunity
Chiyoko Nishime, Kenji Kawai, Takehiro Yamamoto, Ikumi Katano, Makoto Monnai, Nobuhito Goda, Tomoko Mizushima, Hiroshi Suemizu, Masato Nakamura, Mitsuru Murata, Makoto Suematsu and Masatoshi Wakui

J Immunol August 15, 2015, 195 (4) 1883-1890; DOI: https://doi.org/10.4049/jimmunol.1402103
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The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors
Claire Chevaleyre, Nadine Benhamouda, Emmanuel Favry, Elizabeth Fabre, Anais Mhoumadi, Hervé Nozach, Elodie Marcon, Guillaume Cosler, Emeline Vinatier, Stephane Oudard, Stephane Hans, Françoise Le Pimpec-Barthes, Anne-Sophie Bats, Florence A. Castelli, Eric Tartour and Bernard Maillère

J Immunol August 15, 2015, 195 (4) 1891-1901; DOI: https://doi.org/10.4049/jimmunol.1402548

LETTERS OF RETRACTION

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Retraction: TLR4-Dependent NF-κB Activation and Mitogen- and Stress-Activated Protein Kinase 1-Triggered Phosphorylation Events Are Central to Helicobacter pylori Peptidyl Prolyl cis-, trans-Isomerase (HP0175)-Mediated Induction of IL-6 Release from Macrophages
Joyoti Basu and Manikuntala Kundu

J Immunol August 15, 2015, 195 (4) 1902; DOI: https://doi.org/10.4049/jimmunol.1501299

CORRECTIONS

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Correction: miR-182 Is Largely Dispensable for Adaptive Immunity: Lack of Correlation between Expression and Function
Joseph N. Pucella, Wei-Feng Yen, Myoungjoo V. Kim, Joris van der Veeken, Nicholas D. Socci, Yukiko Naito, Ming O. Li, Naoharu Iwai and Jayanta Chaudhuri

J Immunol August 15, 2015, 195 (4) 1903; DOI: https://doi.org/10.4049/jimmunol.1501331

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